PL2913394T3 - Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych - Google Patents

Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych

Info

Publication number
PL2913394T3
PL2913394T3 PL15161369.2T PL15161369T PL2913394T3 PL 2913394 T3 PL2913394 T3 PL 2913394T3 PL 15161369 T PL15161369 T PL 15161369T PL 2913394 T3 PL2913394 T3 PL 2913394T3
Authority
PL
Poland
Prior art keywords
monocytes
differentiation
activation
dendritic cells
allogeneic donors
Prior art date
Application number
PL15161369.2T
Other languages
English (en)
Inventor
Alex Karlsson-Parra
Bengt Andersson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2913394T3 publication Critical patent/PL2913394T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/40Nucleotides, nucleosides, bases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2304Interleukin-4 (IL-4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/24Interferons [IFN]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
    • C12N2506/115Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL15161369.2T 2012-12-18 2013-12-18 Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych PL2913394T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12197687 2012-12-18

Publications (1)

Publication Number Publication Date
PL2913394T3 true PL2913394T3 (pl) 2016-12-30

Family

ID=47427250

Family Applications (2)

Application Number Title Priority Date Filing Date
PL15161369.2T PL2913394T3 (pl) 2012-12-18 2013-12-18 Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych
PL13814106T PL2788474T3 (pl) 2012-12-18 2013-12-18 Wspólne różnicowanie monocytów od dawców allogenicznych

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL13814106T PL2788474T3 (pl) 2012-12-18 2013-12-18 Wspólne różnicowanie monocytów od dawców allogenicznych

Country Status (16)

Country Link
US (2) US9714413B2 (pl)
EP (2) EP2788474B1 (pl)
JP (1) JP6529439B2 (pl)
KR (1) KR102148051B1 (pl)
CN (2) CN110042081B (pl)
AU (1) AU2013360793B2 (pl)
BR (1) BR112015014270B1 (pl)
CA (1) CA2895280C (pl)
DK (2) DK2913394T3 (pl)
ES (2) ES2548229T3 (pl)
HU (2) HUE027619T2 (pl)
MX (1) MX357491B (pl)
PL (2) PL2913394T3 (pl)
RU (1) RU2668816C2 (pl)
SI (2) SI2788474T1 (pl)
WO (1) WO2014096033A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE047540T2 (hu) 2017-09-20 2020-04-28 Immunicum Ab Javított allogén dendritikus sejtek rák kezelésében történõ alkalmazásra
CN112243382A (zh) * 2018-01-18 2021-01-19 南佛罗里达大学 死抗原刺激的未成熟异源性树突细胞作为疾病治疗剂
CN108660125A (zh) * 2018-05-14 2018-10-16 武汉博百欧生物科技有限公司 一种从人体输血废弃物中提取中性粒细胞嗜天青颗粒的方法
WO2020154424A1 (en) * 2019-01-22 2020-07-30 The Brigham And Women's Hospital, Inc. Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2394831A1 (en) * 2000-01-11 2001-07-19 Maxygen, Inc. Monocyte-derived dendritic cell subsets
WO2003010292A2 (en) * 2001-07-25 2003-02-06 Northwest Biotherapeutics, Inc. Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors
WO2003103707A1 (en) 2002-06-06 2003-12-18 Immunicum Ab New method and composition for producing a cellular allogeneic vaccine
KR100585456B1 (ko) * 2003-09-30 2006-06-07 국립암센터 동종 종양-관련 항원이 탑재된 수지상세포, 이의 제조방법및 이를 유효성분으로 하는 암 치료용 백신 조성물
CA2504451A1 (en) * 2004-08-10 2006-02-10 Geron Corporation Dendritic cell vaccines for treating cancer made from embryonic stem cells
JP5954918B2 (ja) * 2005-12-08 2016-07-20 ノースウエスト バイオセラピューティクス, インコーポレイテッド 未成熟な単球性樹状細胞の活性化を誘導するための組成物および方法
EP1806395A1 (en) * 2006-01-06 2007-07-11 Stichting Sanquin Bloedvoorziening Maturation of dendritic cells
EP1840206A1 (en) * 2006-03-28 2007-10-03 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Compositions for the preparation of mature dendritic cells
KR20120093978A (ko) * 2009-10-27 2012-08-23 이뮤니쿰 에이비 항원 특이적 t 세포의 증식 방법
RU2565542C2 (ru) * 2010-02-10 2015-10-20 Иммуникум Аб Улучшенная композиция для ингибирования пролиферации опухолевых клеток
CN103533955A (zh) * 2011-04-13 2014-01-22 因缪尼卡姆股份公司 用于激发t细胞的方法
EP2697367B1 (en) * 2011-04-13 2018-12-19 Immunicum AB Method for proliferation of antigen-specific t cells

Also Published As

Publication number Publication date
HUE027619T2 (en) 2016-10-28
EP2788474A1 (en) 2014-10-15
CN105452449B (zh) 2019-05-07
MX2015007800A (es) 2016-01-12
US20150329823A1 (en) 2015-11-19
PL2788474T3 (pl) 2015-12-31
CA2895280C (en) 2021-04-06
US10626371B2 (en) 2020-04-21
CN110042081A (zh) 2019-07-23
EP2788474B1 (en) 2015-06-24
BR112015014270B1 (pt) 2018-12-04
KR20150122624A (ko) 2015-11-02
WO2014096033A1 (en) 2014-06-26
RU2668816C2 (ru) 2018-10-02
CN105452449A (zh) 2016-03-30
US9714413B2 (en) 2017-07-25
SI2788474T1 (sl) 2016-01-29
DK2913394T3 (en) 2016-09-19
JP6529439B2 (ja) 2019-06-12
ES2591230T3 (es) 2016-11-25
JP2016501529A (ja) 2016-01-21
ES2548229T3 (es) 2015-10-15
KR102148051B1 (ko) 2020-08-25
AU2013360793B2 (en) 2019-01-31
US20170321189A1 (en) 2017-11-09
CA2895280A1 (en) 2014-06-26
RU2015119164A (ru) 2017-01-26
SI2913394T1 (sl) 2017-01-31
CN110042081B (zh) 2023-09-01
BR112015014270A2 (pt) 2015-11-03
EP2913394A1 (en) 2015-09-02
AU2013360793A1 (en) 2015-06-11
DK2788474T3 (en) 2015-09-28
EP2913394B1 (en) 2016-06-22
MX357491B (es) 2018-07-11
HUE028895T2 (en) 2017-02-28

Similar Documents

Publication Publication Date Title
IL264455A (en) Progenitor cells of mesodermal lineage
IL237479A0 (en) Methods and compositions relating to eukaryotic cell modulators
IL233980A0 (en) Compositions and methods for producing a persistent population of t cells useful for the treatment of cancer
EP2836224A4 (en) COMPOSITIONS OF BIOZOOSE AND RELATED METHODS
SG11201408697QA (en) Methods and compositions for natural killer cells
EP2879778A4 (en) HIGHLY EFFICIENT SEPARATION AND MANIPULATION OF PARTICLES AND CELLS
EP2761291A4 (en) SYSTEM AND METHOD FOR SEPARATING CELLS AND / OR PARTICLES
SG10201705024PA (en) Methods and compositions for separating or enriching cells
ZA201404483B (en) Improvements in or relating to the encapsulation of perfumes
IL238943B (en) Controlled release preparations and methods of using them
PL3057604T3 (pl) Kompozycje nanocząstek i sposoby jako nośniki czynników nutraceutycznych przez błony komórkowe i bariery biologiczne
SI3321355T1 (sl) Postopki in sestavki za klinično izpeljavo alogenske celice in terapevtske uporabe
HK1209155A1 (en) Generation of functional and durable endothelial cells from human amniotic fluid-derived cells
EP2825635A4 (en) SYSTEMS AND SUBSTANCES FOR THE CRYOPRESERVATION OF VIABLE CELLS
GB201200458D0 (en) Methods of preparing cells and compositions
SI2913394T1 (sl) Ko-diferenciacija in aktivacija monocitov iz alogenskih darovalcev za zagotovitev proinflamatornih dendričnih celic
EP2878666A4 (en) INDUSTRIAL PREPARATION OF NATURAL KILLING CELLS (NKS) AND INJECTION USING HUMAN ALLOGENIC CARYOCYTES
IL222343A0 (en) Compositions comprising allogeneic th1 cells and uses thereof
SG11201500139SA (en) Derivation and self-renewal of isi1+ cells and uses thereof
ZA201400696B (en) Progenitor cells of mesodermal lineage
GB201205051D0 (en) Improvements in or relating to the encapsulation of perfumes