PL2913394T3 - Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych - Google Patents
Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznychInfo
- Publication number
- PL2913394T3 PL2913394T3 PL15161369.2T PL15161369T PL2913394T3 PL 2913394 T3 PL2913394 T3 PL 2913394T3 PL 15161369 T PL15161369 T PL 15161369T PL 2913394 T3 PL2913394 T3 PL 2913394T3
- Authority
- PL
- Poland
- Prior art keywords
- monocytes
- differentiation
- activation
- dendritic cells
- allogeneic donors
- Prior art date
Links
- 230000004913 activation Effects 0.000 title 1
- 230000000735 allogeneic effect Effects 0.000 title 1
- 210000004443 dendritic cell Anatomy 0.000 title 1
- 210000001616 monocyte Anatomy 0.000 title 1
- 230000000770 proinflammatory effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/40—Nucleotides, nucleosides, bases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2304—Interleukin-4 (IL-4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
- C12N2506/115—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12197687 | 2012-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2913394T3 true PL2913394T3 (pl) | 2016-12-30 |
Family
ID=47427250
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15161369.2T PL2913394T3 (pl) | 2012-12-18 | 2013-12-18 | Wspólne różnicowanie i aktywowanie monocytów od dawców allogenicznych dla dostarczenia prozapalnych komórek dendrytycznych |
PL13814106T PL2788474T3 (pl) | 2012-12-18 | 2013-12-18 | Wspólne różnicowanie monocytów od dawców allogenicznych |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL13814106T PL2788474T3 (pl) | 2012-12-18 | 2013-12-18 | Wspólne różnicowanie monocytów od dawców allogenicznych |
Country Status (16)
Country | Link |
---|---|
US (2) | US9714413B2 (pl) |
EP (2) | EP2788474B1 (pl) |
JP (1) | JP6529439B2 (pl) |
KR (1) | KR102148051B1 (pl) |
CN (2) | CN110042081B (pl) |
AU (1) | AU2013360793B2 (pl) |
BR (1) | BR112015014270B1 (pl) |
CA (1) | CA2895280C (pl) |
DK (2) | DK2913394T3 (pl) |
ES (2) | ES2548229T3 (pl) |
HU (2) | HUE027619T2 (pl) |
MX (1) | MX357491B (pl) |
PL (2) | PL2913394T3 (pl) |
RU (1) | RU2668816C2 (pl) |
SI (2) | SI2788474T1 (pl) |
WO (1) | WO2014096033A1 (pl) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE047540T2 (hu) | 2017-09-20 | 2020-04-28 | Immunicum Ab | Javított allogén dendritikus sejtek rák kezelésében történõ alkalmazásra |
CN112243382A (zh) * | 2018-01-18 | 2021-01-19 | 南佛罗里达大学 | 死抗原刺激的未成熟异源性树突细胞作为疾病治疗剂 |
CN108660125A (zh) * | 2018-05-14 | 2018-10-16 | 武汉博百欧生物科技有限公司 | 一种从人体输血废弃物中提取中性粒细胞嗜天青颗粒的方法 |
WO2020154424A1 (en) * | 2019-01-22 | 2020-07-30 | The Brigham And Women's Hospital, Inc. | Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2394831A1 (en) * | 2000-01-11 | 2001-07-19 | Maxygen, Inc. | Monocyte-derived dendritic cell subsets |
WO2003010292A2 (en) * | 2001-07-25 | 2003-02-06 | Northwest Biotherapeutics, Inc. | Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors |
WO2003103707A1 (en) | 2002-06-06 | 2003-12-18 | Immunicum Ab | New method and composition for producing a cellular allogeneic vaccine |
KR100585456B1 (ko) * | 2003-09-30 | 2006-06-07 | 국립암센터 | 동종 종양-관련 항원이 탑재된 수지상세포, 이의 제조방법및 이를 유효성분으로 하는 암 치료용 백신 조성물 |
CA2504451A1 (en) * | 2004-08-10 | 2006-02-10 | Geron Corporation | Dendritic cell vaccines for treating cancer made from embryonic stem cells |
JP5954918B2 (ja) * | 2005-12-08 | 2016-07-20 | ノースウエスト バイオセラピューティクス, インコーポレイテッド | 未成熟な単球性樹状細胞の活性化を誘導するための組成物および方法 |
EP1806395A1 (en) * | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation of dendritic cells |
EP1840206A1 (en) * | 2006-03-28 | 2007-10-03 | Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh | Compositions for the preparation of mature dendritic cells |
KR20120093978A (ko) * | 2009-10-27 | 2012-08-23 | 이뮤니쿰 에이비 | 항원 특이적 t 세포의 증식 방법 |
RU2565542C2 (ru) * | 2010-02-10 | 2015-10-20 | Иммуникум Аб | Улучшенная композиция для ингибирования пролиферации опухолевых клеток |
CN103533955A (zh) * | 2011-04-13 | 2014-01-22 | 因缪尼卡姆股份公司 | 用于激发t细胞的方法 |
EP2697367B1 (en) * | 2011-04-13 | 2018-12-19 | Immunicum AB | Method for proliferation of antigen-specific t cells |
-
2013
- 2013-12-18 SI SI201330066T patent/SI2788474T1/sl unknown
- 2013-12-18 WO PCT/EP2013/077139 patent/WO2014096033A1/en active Application Filing
- 2013-12-18 BR BR112015014270-2A patent/BR112015014270B1/pt not_active IP Right Cessation
- 2013-12-18 ES ES13814106.4T patent/ES2548229T3/es active Active
- 2013-12-18 CN CN201910284719.5A patent/CN110042081B/zh active Active
- 2013-12-18 EP EP13814106.4A patent/EP2788474B1/en active Active
- 2013-12-18 DK DK15161369.2T patent/DK2913394T3/en active
- 2013-12-18 CN CN201380066722.0A patent/CN105452449B/zh active Active
- 2013-12-18 ES ES15161369.2T patent/ES2591230T3/es active Active
- 2013-12-18 PL PL15161369.2T patent/PL2913394T3/pl unknown
- 2013-12-18 DK DK13814106.4T patent/DK2788474T3/en active
- 2013-12-18 JP JP2015547082A patent/JP6529439B2/ja active Active
- 2013-12-18 MX MX2015007800A patent/MX357491B/es active IP Right Grant
- 2013-12-18 RU RU2015119164A patent/RU2668816C2/ru active
- 2013-12-18 CA CA2895280A patent/CA2895280C/en active Active
- 2013-12-18 PL PL13814106T patent/PL2788474T3/pl unknown
- 2013-12-18 US US14/653,184 patent/US9714413B2/en active Active
- 2013-12-18 AU AU2013360793A patent/AU2013360793B2/en active Active
- 2013-12-18 SI SI201330281A patent/SI2913394T1/sl unknown
- 2013-12-18 EP EP15161369.2A patent/EP2913394B1/en active Active
- 2013-12-18 KR KR1020157015766A patent/KR102148051B1/ko active IP Right Grant
- 2013-12-18 HU HUE13814106A patent/HUE027619T2/en unknown
- 2013-12-18 HU HUE15161369A patent/HUE028895T2/en unknown
-
2017
- 2017-06-15 US US15/623,530 patent/US10626371B2/en active Active
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