PL2858671T3 - Formulacja przeciwciała - Google Patents

Formulacja przeciwciała

Info

Publication number
PL2858671T3
PL2858671T3 PL13744818T PL13744818T PL2858671T3 PL 2858671 T3 PL2858671 T3 PL 2858671T3 PL 13744818 T PL13744818 T PL 13744818T PL 13744818 T PL13744818 T PL 13744818T PL 2858671 T3 PL2858671 T3 PL 2858671T3
Authority
PL
Poland
Prior art keywords
antibody formulation
antibody
formulation
Prior art date
Application number
PL13744818T
Other languages
English (en)
Inventor
Marta Cosenza
Christoph Stark
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48914378&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2858671(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2858671T3 publication Critical patent/PL2858671T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL13744818T 2012-06-12 2013-06-11 Formulacja przeciwciała PL2858671T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261658472P 2012-06-12 2012-06-12
EP13744818.9A EP2858671B1 (en) 2012-06-12 2013-06-11 Antibody formulation
PCT/IB2013/054777 WO2013186700A1 (en) 2012-06-12 2013-06-11 Antibody formulation

Publications (1)

Publication Number Publication Date
PL2858671T3 true PL2858671T3 (pl) 2020-01-31

Family

ID=48914378

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13744818T PL2858671T3 (pl) 2012-06-12 2013-06-11 Formulacja przeciwciała

Country Status (36)

Country Link
US (4) US9216219B2 (pl)
EP (2) EP2858671B1 (pl)
JP (1) JP6265978B2 (pl)
KR (1) KR102124820B1 (pl)
CN (1) CN104363920B (pl)
AR (1) AR091413A1 (pl)
AU (1) AU2013276112B2 (pl)
BR (1) BR112014030820B1 (pl)
CA (1) CA2875386C (pl)
CL (1) CL2014003370A1 (pl)
CO (1) CO7151487A2 (pl)
CY (1) CY1122181T1 (pl)
DK (1) DK2858671T3 (pl)
EA (1) EA033373B1 (pl)
EC (1) ECSP15017314A (pl)
ES (1) ES2751659T3 (pl)
GT (1) GT201400285A (pl)
HK (1) HK1203146A1 (pl)
HR (1) HRP20191827T1 (pl)
HU (1) HUE045523T2 (pl)
IL (1) IL235966B (pl)
LT (1) LT2858671T (pl)
MA (1) MA37616A1 (pl)
MX (1) MX363380B (pl)
MY (1) MY179818A (pl)
NZ (1) NZ630885A (pl)
PE (1) PE20150200A1 (pl)
PH (1) PH12014502778A1 (pl)
PL (1) PL2858671T3 (pl)
PT (1) PT2858671T (pl)
SG (1) SG11201408174UA (pl)
SI (1) SI2858671T1 (pl)
TN (1) TN2014000488A1 (pl)
TW (1) TWI653983B (pl)
WO (1) WO2013186700A1 (pl)
ZA (1) ZA201408547B (pl)

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US9216219B2 (en) * 2012-06-12 2015-12-22 Novartis Ag Anti-BAFFR antibody formulation
TWI595007B (zh) 2012-09-10 2017-08-11 Neotope Biosciences Ltd 抗ｍｃａｍ抗體及相關使用方法
WO2014152232A2 (en) 2013-03-15 2014-09-25 Dyax Corp. Anti-plasma kallikrein antibodies
US10513555B2 (en) * 2013-07-04 2019-12-24 Prothena Biosciences Limited Antibody formulations and methods
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WO2015136472A1 (en) 2014-03-12 2015-09-17 Prothena Biosciences Limited Anti-laminin4 antibodies specific for lg4-5
KR20160127825A (ko) 2014-03-12 2016-11-04 프로테나 바이오사이언시즈 리미티드 항-mcam 항체 및 관련된 사용 방법
KR101597037B1 (ko) 2014-06-26 2016-02-24 엘지디스플레이 주식회사 구동소자의 전기적 특성 편차를 보상할 수 있는 유기발광 표시장치
US10464999B2 (en) 2015-01-28 2019-11-05 Prothena Biosciences Limited Anti-transthyretin antibodies
IL305207A (en) * 2015-03-30 2023-10-01 Takeda Pharmaceuticals Co Plasma kallikrein inhibitors and their uses to prevent the outbreak of hereditary angioedema
JP2018530540A (ja) * 2015-09-16 2018-10-18 プロセナ バイオサイエンシーズ リミテッド 巨細胞動脈炎、リウマチ性多発筋痛症又は高安動脈炎の処置又は予防のための抗ｍｃａｍ抗体の使用
US11058769B2 (en) * 2015-12-07 2021-07-13 Merck Patent Gmbh Aqueous pharmaceutical formulation comprising anti-PD-L1 antibody Avelumab
AU2016366557B2 (en) 2015-12-11 2024-01-25 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
SG11201805123XA (en) * 2015-12-18 2018-07-30 Astellas Pharma Inc Pharmaceutical composition comprising anti-human tslp receptor antibody
BR112018075785A2 (pt) * 2016-06-16 2019-04-02 Janssen Vaccines & Prevention B.V. formulação de vacina para o hiv
CA3041254A1 (en) 2016-10-19 2018-04-26 Invenra Inc. Antibody constructs
KR102312222B1 (ko) 2016-12-22 2021-10-12 우니베르시따 델리 스투디 만냐 그레챠 카탄차로 Ｃｄ43의 독특한 시알로글리코실화된 암-연관 에피토프를 표적으로 하는 모노클로날 항체
CN110366429A (zh) * 2017-03-01 2019-10-22 免疫医疗有限公司 单克隆抗体的配制品
AU2018229724A1 (en) * 2017-03-06 2019-10-31 Merck Patent Gmbh Aqueous anti-PD-L1 antibody formulation
WO2018193471A1 (en) * 2017-04-18 2018-10-25 Dr. Reddy's Laboratories Limited Stable liquid pharmaceutical composition
JP7079844B2 (ja) * 2017-07-27 2022-06-02 アレクシオン ファーマシューティカルズ， インコーポレイテッド 高濃度抗ｃ５抗体製剤
CA3073066A1 (en) * 2017-08-22 2019-02-28 Biogen Ma Inc. Pharmaceutical compositions containing anti-beta amyloid antibodies
BR112020010483A2 (pt) * 2017-11-29 2020-10-20 Prothena Biosciences Limited formulação liofilizada de um anticorpo monoclonal contra transtirretina
CA3102349A1 (en) 2018-06-05 2019-12-12 King's College London Btnl3/8 targeting constructs for delivery of payloads to the gastrointestinal system
JOP20210152A1 (ar) * 2018-12-18 2023-01-30 Novartis Ag صياغة محلول بروتيني محتوية على تركيز عالٍ من جسم مضاد لـ vegf
CA3129901A1 (en) 2019-02-18 2020-08-27 Eli Lilly And Company Therapeutic antibody formulation
JP2022521624A (ja) * 2019-02-26 2022-04-11 イノベント バイオロジックス （スウツォウ） カンパニー，リミテッド 抗ｃｄ４７抗体を含む製剤、その調製方法および使用
JP2023501781A (ja) 2019-11-06 2023-01-19 ノバルティス アーゲー シェーグレン症候群の処置
WO2021136274A1 (zh) * 2019-12-30 2021-07-08 百奥泰生物制药股份有限公司 含抗Trop2抗体-药物偶联物的制剂及其制备方法和应用
CA3168600A1 (en) * 2020-01-21 2021-07-29 Innovent Biologics (Suzhou) Co., Ltd. Recombinant fully human anti-tigit monoclonal antibody formulation, method for preparing same and use thereof
IL300086A (en) 2020-08-04 2023-03-01 Novartis Ag Treatment of B-cell malignancies
CN115073598B (zh) * 2021-03-15 2024-02-20 盛禾(中国)生物制药有限公司 一种抗baffr抗体及其应用
CN117203240A (zh) 2021-05-04 2023-12-08 诺华股份有限公司 使用抗baffr抗体治疗狼疮肾炎
EP4334351A1 (en) 2021-05-04 2024-03-13 Novartis AG Treatment for systemic lupus erythematosus using anti-baffr antibodies
TW202330604A (zh) * 2021-09-29 2023-08-01 美商蜻蜓醫療公司 靶向ｂａｆｆ—ｒ的抗體及其用途

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Also Published As

Publication number Publication date
KR102124820B1 (ko) 2020-06-22
WO2013186700A1 (en) 2013-12-19
US9216219B2 (en) 2015-12-22
US20130344088A1 (en) 2013-12-26
CN104363920A (zh) 2015-02-18
SG11201408174UA (en) 2015-01-29
US20180051092A1 (en) 2018-02-22
SI2858671T1 (sl) 2019-11-29
CA2875386A1 (en) 2013-12-19
US9751951B2 (en) 2017-09-05
JP2015521593A (ja) 2015-07-30
HRP20191827T1 (hr) 2019-12-27
BR112014030820A2 (pt) 2017-07-25
ES2751659T3 (es) 2020-04-01
NZ630885A (en) 2016-01-29
CY1122181T1 (el) 2020-11-25
MY179818A (en) 2020-11-16
TW201402144A (zh) 2014-01-16
TWI653983B (zh) 2019-03-21
CL2014003370A1 (es) 2015-02-06
EP2858671B1 (en) 2019-07-24
KR20150029683A (ko) 2015-03-18
PH12014502778B1 (en) 2015-02-02
AU2013276112B2 (en) 2015-07-09
BR112014030820B1 (pt) 2023-02-07
CA2875386C (en) 2022-09-13
CO7151487A2 (es) 2014-12-29
MX363380B (es) 2019-03-21
DK2858671T3 (da) 2019-10-21
JP6265978B2 (ja) 2018-01-24
EA033373B1 (ru) 2019-10-31
HK1203146A1 (en) 2015-10-23
US10689451B2 (en) 2020-06-23
CN104363920B (zh) 2018-05-04
AR091413A1 (es) 2015-02-04
MX2014015262A (es) 2015-06-23
US20180251564A1 (en) 2018-09-06
AU2013276112A1 (en) 2014-12-18
EP2858671A1 (en) 2015-04-15
GT201400285A (es) 2015-10-15
ECSP15017314A (es) 2018-06-30
IL235966B (en) 2020-05-31
EA201492292A1 (ru) 2015-04-30
HUE045523T2 (hu) 2020-01-28
TN2014000488A1 (en) 2016-03-30
PT2858671T (pt) 2019-10-28
PH12014502778A1 (en) 2015-02-02
PE20150200A1 (es) 2015-02-08
LT2858671T (lt) 2019-10-25
ZA201408547B (en) 2015-12-23
MA37616A1 (fr) 2017-08-31
US20160145341A1 (en) 2016-05-26
EP3593814A1 (en) 2020-01-15
IL235966A0 (en) 2015-01-29

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