PL2744772T3 - Sposób wytwarzania sewofluranu - Google Patents

Sposób wytwarzania sewofluranu

Info

Publication number
PL2744772T3
PL2744772T3 PL12762694T PL12762694T PL2744772T3 PL 2744772 T3 PL2744772 T3 PL 2744772T3 PL 12762694 T PL12762694 T PL 12762694T PL 12762694 T PL12762694 T PL 12762694T PL 2744772 T3 PL2744772 T3 PL 2744772T3
Authority
PL
Poland
Prior art keywords
sevoflurane
manufacturing
Prior art date
Application number
PL12762694T
Other languages
English (en)
Inventor
Linas Kudzma
Ronald Bell
Yongxian Zeng
Leonid A Rozov
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of PL2744772T3 publication Critical patent/PL2744772T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/18Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/34Separation; Purification; Stabilisation; Use of additives
    • C07C41/38Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/34Separation; Purification; Stabilisation; Use of additives
    • C07C41/40Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
    • C07C41/42Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04Saturated ethers
    • C07C43/12Saturated ethers containing halogen
    • C07C43/123Saturated ethers containing halogen both carbon chains are substituted by halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
PL12762694T 2011-08-15 2012-08-03 Sposób wytwarzania sewofluranu PL2744772T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/210,272 US8729313B2 (en) 2011-08-15 2011-08-15 Process for the manufacturing of sevoflurane
EP12762694.3A EP2744772B1 (en) 2011-08-15 2012-08-03 Process for the manufacturing of sevoflurane
PCT/US2012/049558 WO2013025377A1 (en) 2011-08-15 2012-08-03 Process for the manufacturing of sevoflurane

Publications (1)

Publication Number Publication Date
PL2744772T3 true PL2744772T3 (pl) 2015-11-30

Family

ID=46924518

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12762694T PL2744772T3 (pl) 2011-08-15 2012-08-03 Sposób wytwarzania sewofluranu

Country Status (9)

Country Link
US (1) US8729313B2 (pl)
EP (1) EP2744772B1 (pl)
JP (1) JP5926802B2 (pl)
CN (1) CN103635451B (pl)
AU (1) AU2012295410B2 (pl)
BR (1) BR112013033851A2 (pl)
MX (1) MX353760B (pl)
PL (1) PL2744772T3 (pl)
WO (1) WO2013025377A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9102604B1 (en) * 2010-02-15 2015-08-11 Baxter International Inc. Methods for cleaning distilling columns
CA3014020C (en) 2016-02-23 2021-01-05 Sagetech Medical Equipment Limited Improvements to the manufacture and remanufacture of volatile anaesthetic agents using supercritical fluids
US10035745B1 (en) 2016-07-30 2018-07-31 Baxter International Inc. Methods of purifying crude sevoflurane
JP6299905B1 (ja) * 2017-02-06 2018-03-28 セントラル硝子株式会社 セボフルランの製造方法
CN108689808B (zh) * 2017-04-06 2021-11-16 江苏恒瑞医药股份有限公司 一种氯甲基六氟异丙醚的制备方法
CN113943214B (zh) * 2021-11-11 2023-12-19 福建海西联合药业有限公司 一种运用于七氟烷生产的工艺

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3476860A (en) 1966-12-08 1969-11-04 Air Reduction Halomethyl fluoroisopropyl ethers as anesthetic agents
US3527814A (en) 1968-03-08 1970-09-08 Air Reduction Halomethyl fluoroisopropyl ethers
US4250334A (en) 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4469898A (en) 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US5233098A (en) 1990-05-30 1993-08-03 Central Glass Company, Limited Method for removing and recovering fluorinated alcohol from waste gas
JP2865554B2 (ja) 1994-04-08 1999-03-08 セントラル硝子株式会社 フルオロメチル−1,1,1,3,3,3−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
GB9600072D0 (en) 1996-01-04 1996-03-06 Ici Plc Process for the production of fluoromethylhexafluoroisopropylether
JP3441735B2 (ja) 1996-02-21 2003-09-02 セントラル硝子株式会社 フルオロメチル−1,1,1,3,3,3−ヘキサフルオロイソプロピルエーテルの製造方法
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
US6100434A (en) 1999-03-26 2000-08-08 Abbott Laboratories Method for synthesizing sevoflurane and an intermediate thereof
US6469219B1 (en) 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
GB0031301D0 (en) 2000-12-21 2001-01-31 Ici Plc Process for the production of fluoromethyl hexafluoroisopropyl ether
GB0031310D0 (en) 2000-12-21 2001-01-31 Ici Plc Process for the purification of fluoromethyl hexafluoroisopropyl ether
US6987204B2 (en) 2003-01-14 2006-01-17 Baxter International Inc. Process for recovery of 1,1,1,3,3,3-hexafluoroisopropanol from the waste stream of sevoflurane synthesis
PL380525A1 (pl) 2004-01-05 2007-02-19 Halocarbon Products Corporation Chromatograficzna metoda analizy zarówno w sposobie wytwarzania sewofluranu, jak też w końcowym sewofluranie
JP4875626B2 (ja) * 2004-11-17 2012-02-15 ピラマル クリティカル ケアー インコーポレイテッド セボフルランの調製のための方法
WO2008037040A2 (en) * 2006-09-29 2008-04-03 Cristália Produtos Químicos Farmacêuticos Ltda. Process for the preparation of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether
CN101337863B (zh) * 2007-07-06 2012-04-25 江苏恒瑞医药股份有限公司 一种制备七氟烷的方法
CN101314560B (zh) * 2008-07-02 2011-06-15 鲁南制药集团股份有限公司 七氟烷的合成方法

Also Published As

Publication number Publication date
MX353760B (es) 2018-01-26
US20130046117A1 (en) 2013-02-21
MX2014001828A (es) 2014-02-27
JP2014525409A (ja) 2014-09-29
AU2012295410B2 (en) 2014-10-30
JP5926802B2 (ja) 2016-05-25
AU2012295410A1 (en) 2013-05-02
US8729313B2 (en) 2014-05-20
WO2013025377A1 (en) 2013-02-21
EP2744772B1 (en) 2015-07-01
BR112013033851A2 (pt) 2017-02-07
CN103635451A (zh) 2014-03-12
CN103635451B (zh) 2016-08-24
EP2744772A1 (en) 2014-06-25

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