PL2665734T3 - Sposób wytwarzania związków zawierających grupę alfa-oksyfosforową - Google Patents

Sposób wytwarzania związków zawierających grupę alfa-oksyfosforową

Info

Publication number
PL2665734T3
PL2665734T3 PL12701856.2T PL12701856T PL2665734T3 PL 2665734 T3 PL2665734 T3 PL 2665734T3 PL 12701856 T PL12701856 T PL 12701856T PL 2665734 T3 PL2665734 T3 PL 2665734T3
Authority
PL
Poland
Prior art keywords
alpha
manufacture
compounds containing
phosphorus group
oxy phosphorus
Prior art date
Application number
PL12701856.2T
Other languages
English (en)
Inventor
Sebastian R. W. Burck
Samuel Corentin Cogels
Patrick Notté
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2665734T3 publication Critical patent/PL2665734T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • C07F9/53Organo-phosphine oxides; Organo-phosphine thioxides
    • C07F9/5325Aromatic phosphine oxides or thioxides (P-C aromatic linkage)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • C07F9/5728Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505Phosphonic acids containing oxirane groups; esters thereof
PL12701856.2T 2011-01-21 2012-01-23 Sposób wytwarzania związków zawierających grupę alfa-oksyfosforową PL2665734T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11151659 2011-01-21

Publications (1)

Publication Number Publication Date
PL2665734T3 true PL2665734T3 (pl) 2016-12-30

Family

ID=43971513

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12701856.2T PL2665734T3 (pl) 2011-01-21 2012-01-23 Sposób wytwarzania związków zawierających grupę alfa-oksyfosforową

Country Status (3)

Country Link
EP (1) EP2665734B1 (pl)
PL (1) PL2665734T3 (pl)
WO (1) WO2012098255A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
RU2016118639A (ru) * 2013-10-25 2017-11-30 Страйтмарк Холдинг Аг Способ синтеза алкан-1-гидрокси-1,1-дифосфоновой кислоты
RU2016118638A (ru) * 2013-10-25 2017-11-28 Страйтмарк Холдинг Аг Способ синтеза этан-1-гидрокси-1,1-дифосфоновой кислоты

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1212931A (en) 1967-03-30 1970-11-18 Stauffer Chemical Co Phosphorus compounds containing phosphorus to carbon linkages
HUP0300227A2 (hu) * 2003-01-28 2004-09-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás nagy tisztaságú 2-szubsztituált -1-(hidroxi-etilidén)-1,1-biszfoszfonsavak és sóik előállítására
ES2324015T1 (es) * 2005-05-06 2009-07-29 Medichem, S.A. Proceso de sintesis de acidos bisfosfonicos geminales o de sus sales farmaceuticamente aceptables o de sus hidratos.
CL2008003539A1 (es) 2007-11-28 2009-07-03 Procedimiento para la produccion de p4o6 que comprende mezclar o2 o una mezcla de o2 mas un gas inerte y fosforo en donde el producto obtenido se mantiene dentro de una unidad de reaccion a una temperatura entre los 1600 y 2000 k durante por lo menos 1 segundo.
CN102448973A (zh) * 2009-05-28 2012-05-09 施里特马克控股公司 用于制备二烷基亚磷酸盐的方法

Also Published As

Publication number Publication date
EP2665734B1 (en) 2016-06-29
EP2665734A1 (en) 2013-11-27
WO2012098255A1 (en) 2012-07-26

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