PL2648702T3 - Stabilne musujące formulacje bisfosfonianowe z cechą szybkiej solubilizacji - Google Patents

Stabilne musujące formulacje bisfosfonianowe z cechą szybkiej solubilizacji

Info

Publication number
PL2648702T3
PL2648702T3 PL11846465T PL11846465T PL2648702T3 PL 2648702 T3 PL2648702 T3 PL 2648702T3 PL 11846465 T PL11846465 T PL 11846465T PL 11846465 T PL11846465 T PL 11846465T PL 2648702 T3 PL2648702 T3 PL 2648702T3
Authority
PL
Poland
Prior art keywords
rapid solubilization
solubilization characteristics
bisphosphonate formulations
stable effervescent
effervescent bisphosphonate
Prior art date
Application number
PL11846465T
Other languages
English (en)
Inventor
Marshall A. Hayward
Timo Schmidt
Original Assignee
Effrx Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Effrx Pharmaceuticals Sa filed Critical Effrx Pharmaceuticals Sa
Publication of PL2648702T3 publication Critical patent/PL2648702T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
PL11846465T 2010-12-06 2011-12-05 Stabilne musujące formulacje bisfosfonianowe z cechą szybkiej solubilizacji PL2648702T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41997210P 2010-12-06 2010-12-06
EP11846465.0A EP2648702B1 (en) 2010-12-06 2011-12-05 Stable effervescent bisphosphonate formulations with rapid solubilization characteristics
PCT/US2011/063341 WO2012078528A2 (en) 2010-12-06 2011-12-05 Stable effervescent bisphosphonate formulations with rapid solubilization characteristics

Publications (1)

Publication Number Publication Date
PL2648702T3 true PL2648702T3 (pl) 2019-07-31

Family

ID=46207670

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11846465T PL2648702T3 (pl) 2010-12-06 2011-12-05 Stabilne musujące formulacje bisfosfonianowe z cechą szybkiej solubilizacji

Country Status (17)

Country Link
US (1) US9592195B2 (pl)
EP (1) EP2648702B1 (pl)
KR (3) KR20180115254A (pl)
CN (1) CN103140220A (pl)
AU (1) AU2011338674B2 (pl)
BR (1) BR112013010476B1 (pl)
CA (1) CA2820019A1 (pl)
DK (1) DK2648702T3 (pl)
ES (1) ES2716525T3 (pl)
IL (1) IL224367B (pl)
MY (1) MY166971A (pl)
PL (1) PL2648702T3 (pl)
PT (1) PT2648702T (pl)
RU (1) RU2608724C2 (pl)
TR (1) TR201903835T4 (pl)
WO (1) WO2012078528A2 (pl)
ZA (1) ZA201302093B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104382004A (zh) * 2013-08-19 2015-03-04 宣城柏维力生物工程有限公司 一种针叶樱桃vc泡腾片
CN103919890A (zh) * 2014-04-03 2014-07-16 中国计量学院 常山胡柚果皮果渣提取物的泡腾片的制备方法
CN103961372B (zh) * 2014-05-27 2018-07-10 湖北凤凰白云山药业有限公司 一种中性磷酸盐粉剂
AU2015316552C1 (en) 2014-09-17 2018-08-23 Steerlife India Private Limited Effervescent composition and method of making it
US11219594B2 (en) 2015-12-12 2022-01-11 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
KR20220084089A (ko) * 2019-10-17 2022-06-21 아이에스피 인베스트먼츠 엘엘씨 안정한 발포성 공동-처리 부형제 조성물 및 그의 제조 방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1195993B (it) 1984-01-12 1988-11-03 Gentili Ist Spa Forme farmaceutiche a base di difosfonati
US4687662A (en) * 1985-08-30 1987-08-18 Warner-Lambert Company Therapeutic effervescent composition
US4922007A (en) 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
US5019651A (en) 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof
JP3517233B2 (ja) * 1991-07-01 2004-04-12 ゲルゲリイ、ゲルハルト 反応注入した発泡システム
US5510517A (en) 1993-08-25 1996-04-23 Merck & Co., Inc. Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids
US5646134A (en) 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
EP0998292B1 (en) * 1997-07-22 2001-11-21 Merck & Co., Inc. (a New Jersey corp.) Method for inhibiting bone resorption
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
CA2495886C (en) * 2002-03-06 2011-05-03 Lifizz, Inc. Effervescent compositions comprising bisphosphonates and methods related thereto
US20050214425A1 (en) * 2004-03-23 2005-09-29 Roma Vazirani Sugar substitute prepared with nutritive and high-intensity sweeteners
TR200900879A2 (tr) 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Aktif maddelerin tek bir dozaj formunda kombine edildiği farmasötik bileşimler
US9208302B2 (en) 2012-09-28 2015-12-08 Intel Corporation Multi-factor authentication using biometric data

Also Published As

Publication number Publication date
BR112013010476A2 (pt) 2016-08-02
KR20140075638A (ko) 2014-06-19
CA2820019A1 (en) 2012-06-14
KR102011505B1 (ko) 2019-08-16
KR20170104664A (ko) 2017-09-15
ES2716525T3 (es) 2019-06-13
IL224367B (en) 2020-05-31
AU2011338674B2 (en) 2017-03-30
EP2648702B1 (en) 2019-03-06
KR20180115254A (ko) 2018-10-22
WO2012078528A3 (en) 2012-08-02
RU2013109765A (ru) 2014-09-10
EP2648702A2 (en) 2013-10-16
AU2011338674A1 (en) 2013-07-04
RU2608724C2 (ru) 2017-01-23
MY166971A (en) 2018-07-26
US20130287706A1 (en) 2013-10-31
TR201903835T4 (tr) 2019-04-22
PT2648702T (pt) 2019-03-29
CN103140220A (zh) 2013-06-05
WO2012078528A2 (en) 2012-06-14
EP2648702A4 (en) 2016-07-20
BR112013010476B1 (pt) 2021-07-06
ZA201302093B (en) 2013-11-27
DK2648702T3 (en) 2019-04-08
US9592195B2 (en) 2017-03-14

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