PL253821A1 - Method of obtaining derivatives of 1,4-dihydropyridine - Google Patents

Method of obtaining derivatives of 1,4-dihydropyridine

Info

Publication number
PL253821A1
PL253821A1 PL25382185A PL25382185A PL253821A1 PL 253821 A1 PL253821 A1 PL 253821A1 PL 25382185 A PL25382185 A PL 25382185A PL 25382185 A PL25382185 A PL 25382185A PL 253821 A1 PL253821 A1 PL 253821A1
Authority
PL
Poland
Prior art keywords
dihydropyridine
obtaining derivatives
derivatives
obtaining
Prior art date
Application number
PL25382185A
Inventor
David Alker
Simon F Campbell
Peter E Cross
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848414520A external-priority patent/GB8414520D0/en
Priority claimed from GB858508736A external-priority patent/GB8508736D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of PL253821A1 publication Critical patent/PL253821A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL25382185A 1984-06-07 1985-06-05 Method of obtaining derivatives of 1,4-dihydropyridine PL253821A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848414520A GB8414520D0 (en) 1984-06-07 1984-06-07 Dihydropyridines
GB858508736A GB8508736D0 (en) 1985-04-03 1985-04-03 Dihydropyridines

Publications (1)

Publication Number Publication Date
PL253821A1 true PL253821A1 (en) 1986-07-01

Family

ID=26287832

Family Applications (1)

Application Number Title Priority Date Filing Date
PL25382185A PL253821A1 (en) 1984-06-07 1985-06-05 Method of obtaining derivatives of 1,4-dihydropyridine

Country Status (14)

Country Link
US (1) US4618609A (en)
EP (1) EP0164247B1 (en)
JP (1) JPH0641464B2 (en)
AU (1) AU556496B2 (en)
DE (1) DE3567460D1 (en)
DK (1) DK170402B1 (en)
ES (1) ES8700857A1 (en)
FI (1) FI852222L (en)
GR (1) GR851383B (en)
HU (1) HUT41404A (en)
IE (1) IE57816B1 (en)
IL (1) IL75411A0 (en)
PL (1) PL253821A1 (en)
PT (1) PT80597B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
EP0233228A1 (en) * 1985-08-06 1987-08-26 Boehringer Mannheim Italia S.P.A. Pharmaceutically active 2-thiomethyl-substituted-1,4-dihydropyridines
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents
US4761420A (en) * 1986-06-13 1988-08-02 Laboratoires Syntex S.A. Antihypertensive dihydropyridine derivatives
US4920134A (en) * 1987-08-07 1990-04-24 Takeda Chemical Industries, Ltd. 2-O-pyrimidinyl glycerol derivatives
US5691360A (en) * 1993-12-08 1997-11-25 Alcon Laboratories, Inc. Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
US5424321A (en) * 1993-12-08 1995-06-13 Alcon Laboratories, Inc. Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
AU2004315596B2 (en) * 2003-08-29 2011-11-24 President And Fellows Of Harvard College Inhibitors of cellular necrosis
WO2010075290A1 (en) * 2008-12-22 2010-07-01 President And Fellows Of Harvard College Unsaturated heterocyclic inhibitors of necroptosis
CA2772760A1 (en) 2008-12-23 2010-07-01 President And Fellows Of Harvard College Small molecule inhibitors of necroptosis
WO2014145022A1 (en) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Hybrid necroptosis inhibitors
US9944628B2 (en) 2014-12-11 2018-04-17 President And Fellows Of Harvard College Inhibitors of cellular necrosis and related methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2951945A1 (en) * 1979-12-22 1981-07-02 Ibm Deutschland Gmbh, 7000 Stuttgart CIRCUIT ARRANGEMENT FOR CAPACITIVE READING SIGNAL AMPLIFICATION IN AN INTEGRATED SEMICONDUCTOR STORAGE WITH AN INTEGRATED SEMICONDUCTOR STORAGE WITH STORAGE CELLS IN MTL TECHNOLOGY
ATE20064T1 (en) * 1982-07-22 1986-06-15 Pfizer ANTI-ISCHEMIC AND ANTI-HYPERTENSIVE DIHYDROPYRIDIN DERIVATIVES.
PT77842B (en) * 1982-12-21 1986-05-05 Pfizer Process for preparing dihydropyridines
US4515799A (en) * 1983-02-02 1985-05-07 Pfizer Inc. Dihydropyridine anti-ischaemic and antihypertensive agents

Also Published As

Publication number Publication date
PT80597A (en) 1985-07-01
FI852222A0 (en) 1985-06-03
ES8700857A1 (en) 1986-11-16
AU556496B2 (en) 1986-11-06
DK253785A (en) 1985-12-08
ES543999A0 (en) 1986-11-16
IL75411A0 (en) 1985-10-31
DE3567460D1 (en) 1989-02-16
HUT41404A (en) 1987-04-28
IE851417L (en) 1985-12-07
DK253785D0 (en) 1985-06-06
PT80597B (en) 1987-04-23
EP0164247B1 (en) 1989-01-11
FI852222L (en) 1985-12-08
IE57816B1 (en) 1993-04-21
GR851383B (en) 1985-11-25
US4618609A (en) 1986-10-21
EP0164247A1 (en) 1985-12-11
JPS611685A (en) 1986-01-07
DK170402B1 (en) 1995-08-21
AU4334985A (en) 1985-12-12
JPH0641464B2 (en) 1994-06-01

Similar Documents

Publication Publication Date Title
PL256983A1 (en) Method of obtaining novel derivatives of cyclohexanodione-1,3
PL256985A1 (en) Method of obtaining novel derivatives of cyclohexanodione-1,3
PL254207A1 (en) Method of obtaining derivatives of ganglyosides
PL253108A1 (en) Method of obtaining novel derivatives of 1,4-dihydronaphtidrine and their salts
PL251972A1 (en) Method of obtaining derivatives of pleuromutiline
PL252773A1 (en) Method of obtaining novel derivatives of 1,4-dihydropyridine
PL256984A1 (en) Method of obtaining novel derivatives of cyclohexanodione-1,3
GB8515413D0 (en) 1 4-dihydropyridine derivatives
BG43865A3 (en) Method for preparing of 1, 3- disubstituted 2- oxyindols
PL268618A1 (en) The method of manufacture of 1,4-dihydropyridine derivatives
PL253821A1 (en) Method of obtaining derivatives of 1,4-dihydropyridine
PL253820A1 (en) Method of obtaining derivatives of 1,4-dihydropyridine
PL264492A1 (en) Method of obtaining 1,2,4,-triazolcarbaminates
PL251584A1 (en) Method of obtaining novel derivatives of 1,4-dihydropyridine
PL255723A1 (en) Method of obtaining derivatives of 1,6-phenoxyprostatrienic acid
PL253089A1 (en) Method of obtaining novel derivatives of iminotriazolidine
PL267418A1 (en) Method of obtaining derivatives of 2,3-dihydrofurene
PL257668A1 (en) Method of obtaining novel derivatives of 4,4-dialkylazethydinone
PL251456A1 (en) Method of obtaining derivatives of thioxantene
PL255399A1 (en) Method of obtaining 1,3-diacyl-2-ketoindoles
PL256694A1 (en) Method of obtaining derivatives of 1,4-dihydropyridine
PL266240A1 (en) Method of obtaining derivatives of 1,3,2-oxazaphosphorinate
PL257530A1 (en) Method of obtaining novel derivatives of 1,4-dihydropyridine
PL271920A1 (en) Method for manufacturing new derivatives of 1,4 - dihydropyridine
PL250146A1 (en) Method of obtaining derivatives of 1,2-dithiolate