PL2448600T3 - Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu - Google Patents

Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu

Info

Publication number
PL2448600T3
PL2448600T3 PL10727003.5T PL10727003T PL2448600T3 PL 2448600 T3 PL2448600 T3 PL 2448600T3 PL 10727003 T PL10727003 T PL 10727003T PL 2448600 T3 PL2448600 T3 PL 2448600T3
Authority
PL
Poland
Prior art keywords
cation
compounds targeting
phosphate receptor
independent mannose
mannose
Prior art date
Application number
PL10727003.5T
Other languages
English (en)
Inventor
Marcel Garcia
Alain Morere
Magali Gary-Bobo
Martine Cerutti
Cheikh Khaled El
Ilaria Basile
Philippe Nirde
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2448600T3 publication Critical patent/PL2448600T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549Sugars, nucleosides, nucleotides or nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL10727003.5T 2009-07-03 2010-07-02 Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu PL2448600T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09305647 2009-07-03

Publications (1)

Publication Number Publication Date
PL2448600T3 true PL2448600T3 (pl) 2016-10-31

Family

ID=41279432

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10727003.5T PL2448600T3 (pl) 2009-07-03 2010-07-02 Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu

Country Status (7)

Country Link
US (1) US8962573B2 (pl)
EP (1) EP2448600B1 (pl)
JP (1) JP5837486B2 (pl)
CA (1) CA2766614C (pl)
ES (1) ES2576853T3 (pl)
PL (1) PL2448600T3 (pl)
WO (1) WO2011000958A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102985538B (zh) 2010-04-23 2015-09-09 辛那杰瓦生物制药股份有限公司 溶酶体贮积病酶
RS53947B1 (en) 2010-09-09 2015-08-31 Synageva Biopharma Corp. Administration of Lysosomal Acid Lipase for the Treatment of Lysosomal Acid Lipase Deficiency in Patients
JP5665065B2 (ja) * 2011-04-28 2015-02-04 国立大学法人大阪大学 リソソーム病治療用医薬組成物
RU2014117291A (ru) * 2011-10-12 2015-11-20 Синаджева Биофарма Корп. Рекомбинантный человеческий белок naglu и его применение
CN104661684B (zh) 2012-08-16 2018-03-20 辉瑞公司 糖缀合方法和组合物
CN102993256B (zh) * 2012-12-31 2016-05-18 浙江大学 一种选择性脱除全三甲基硅基保护糖的伯位三甲基硅基的方法
US20160022826A1 (en) * 2013-03-15 2016-01-28 Newlink Genetics Corporation Carbohydrate-modified glycoproteins and uses thereof
FR3041345B1 (fr) * 2015-09-18 2019-06-14 Nanomedsyn Composes polysaccharides multi-fonctionnalises et leur utilisation pour cibler le recepteur du mannose 6-phosphate cation-independant
AU2016349528A1 (en) 2015-11-06 2018-05-17 Biomarin Pharmaceutical Inc. Cell-based assays for detection of antibodies or other factors that neutralize uptake of lysosomal enzymes
EP4356964A3 (en) * 2018-08-10 2024-06-19 New York University Use of igf-2 receptor agonist ligands for treatment of angelman syndrome and autism
AU2019320099A1 (en) * 2018-08-10 2021-04-01 New York University Use of mannose 6 phosphate and modifications thereof for memory enhancement and reducing memory impairment
CA3123086A1 (en) 2018-12-19 2020-06-25 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules for lysosomal targeting and related compositions and methods
CN110893236A (zh) * 2019-10-09 2020-03-20 中山大学 溶酶体靶向的抗体药物偶联物及其应用
FR3132634A1 (fr) * 2022-02-15 2023-08-18 Nanomedsyn Composés bifonctionnels ciblant le récepteur du mannose 6-phosphate cation-indépendant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2345932C (en) * 1998-10-08 2010-07-13 Stichting Voor De Technische Wetenschappen Peptide-based carrier devices for stellate cells
US7001994B2 (en) 2001-01-18 2006-02-21 Genzyme Corporation Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins
US7365178B2 (en) 2003-04-01 2008-04-29 Activx Biosciences, Inc. Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis
DK1495769T3 (da) 2003-07-11 2008-06-23 Lbr Medbiotech B V Mannose-6-phosphat-receptormedieret gentransfer til muskelceller
GB0326546D0 (en) * 2003-11-14 2003-12-17 Amersham Plc Inhibitor imaging agents
JP2008504531A (ja) * 2004-06-24 2008-02-14 ザ スクリップス リサーチ インスティテュート 切断可能なリンカーを有するアレイ
WO2008089339A2 (en) * 2007-01-18 2008-07-24 Genzyme Corporation Oligosaccharide conjugates for cellular targeting
NO2457920T3 (pl) 2007-01-18 2018-03-24
JP5069920B2 (ja) 2007-02-08 2012-11-07 公益財団法人東京都医学総合研究所 マンノース6−リン酸−ポリエチレングリコール結合体
AU2008237932C1 (en) * 2007-04-11 2014-04-24 Merck & Cie 18 F-labelled folates
EP2192924B1 (en) 2007-08-20 2017-10-11 Protalix Ltd. Saccharide-containing protein conjugates and uses thereof

Also Published As

Publication number Publication date
JP2012531458A (ja) 2012-12-10
EP2448600A1 (en) 2012-05-09
US8962573B2 (en) 2015-02-24
CA2766614A1 (en) 2011-01-06
EP2448600B1 (en) 2016-03-30
ES2576853T3 (es) 2016-07-11
WO2011000958A1 (en) 2011-01-06
US20120093795A1 (en) 2012-04-19
CA2766614C (en) 2018-06-19
JP5837486B2 (ja) 2015-12-24

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