PL2320739T3 - Kompozycje farmaceutyczne i sposoby ich stabilizowania - Google Patents

Kompozycje farmaceutyczne i sposoby ich stabilizowania

Info

Publication number
PL2320739T3
PL2320739T3 PL09803270T PL09803270T PL2320739T3 PL 2320739 T3 PL2320739 T3 PL 2320739T3 PL 09803270 T PL09803270 T PL 09803270T PL 09803270 T PL09803270 T PL 09803270T PL 2320739 T3 PL2320739 T3 PL 2320739T3
Authority
PL
Poland
Prior art keywords
stabilizing
methods
same
pharmaceutical compositions
pharmaceutical
Prior art date
Application number
PL09803270T
Other languages
English (en)
Inventor
Rajeshwar Motheram
Gopal Krishna
Ding Min
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of PL2320739T3 publication Critical patent/PL2320739T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
PL09803270T 2008-08-01 2009-07-30 Kompozycje farmaceutyczne i sposoby ich stabilizowania PL2320739T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8559408P 2008-08-01 2008-08-01
US9381008P 2008-09-03 2008-09-03
PCT/US2009/004399 WO2010014234A1 (en) 2008-08-01 2009-07-30 Pharmaceutical compositions and methods for stabilizing the same
EP09803270.9A EP2320739B1 (en) 2008-08-01 2009-07-30 Pharmaceutical compositions and methods for stabilizing the same

Publications (1)

Publication Number Publication Date
PL2320739T3 true PL2320739T3 (pl) 2020-06-01

Family

ID=41610652

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09803270T PL2320739T3 (pl) 2008-08-01 2009-07-30 Kompozycje farmaceutyczne i sposoby ich stabilizowania

Country Status (21)

Country Link
US (4) US20100105743A1 (pl)
EP (1) EP2320739B1 (pl)
JP (4) JP2011529879A (pl)
KR (4) KR20160095206A (pl)
CN (2) CN106377501A (pl)
AU (1) AU2009277100B2 (pl)
BR (1) BRPI0917562B8 (pl)
CA (1) CA2732692C (pl)
CY (1) CY1122526T1 (pl)
DK (1) DK2320739T3 (pl)
EA (1) EA201170287A1 (pl)
ES (1) ES2770178T3 (pl)
HR (1) HRP20200136T1 (pl)
HU (1) HUE047692T2 (pl)
LT (1) LT2320739T (pl)
MX (1) MX2011001241A (pl)
NZ (1) NZ591204A (pl)
PL (1) PL2320739T3 (pl)
PT (1) PT2320739T (pl)
SI (1) SI2320739T1 (pl)
WO (1) WO2010014234A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102665413A (zh) * 2009-09-30 2012-09-12 微剂量治疗技术公司 治疗雷诺氏现象的方法和组合物
BR112013008601B1 (pt) * 2010-10-12 2020-03-31 Chiesi Farmaceutici S.P.A. Formulações de emulsão de clevidipina contendo agentes antimicrobianos
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EP2694063A1 (en) * 2011-04-01 2014-02-12 The Medicines Company Short -acting dihydropyridines (clevidipine) for use in reducing stroke damage
CN103134891A (zh) * 2011-11-30 2013-06-05 天津金耀集团有限公司 一种丁酸氯维地平含量和有关物质的测定方法
ES2671639T3 (es) 2012-10-26 2018-06-07 Chiesi Farmaceutici S.P.A. Métodos para controlar la presión arterial y reducir la disnea en la insuficiencia cardiaca
CN103520104B (zh) * 2013-10-25 2015-08-26 北京蓝丹医药科技有限公司 丁酸氯维地平脂肪乳注射液及其制备方法
CN109776405A (zh) * 2019-03-07 2019-05-21 重庆安格龙翔医药科技有限公司 一种丁酸氯维地平杂质的制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756779A (fr) * 1969-09-30 1971-03-01 Warner Lambert Pharmaceutical Solutions stables de cardenolides sensibles a l'oxydation
US4150744A (en) * 1976-02-27 1979-04-24 Smith & Nephew Pharmaceuticals Ltd. Packaging
DE3532129A1 (de) * 1985-09-10 1987-03-12 Bayer Ag Ss-carotin enthaltende gelatine
US5651991A (en) * 1987-10-28 1997-07-29 Nippon Shinyaku Co. Ltd. Drug carriers
CA2013755C (en) * 1989-04-05 1993-11-30 Simon Benita Medicinal emulsions
SE9303744D0 (sv) 1993-11-12 1993-11-12 Astra Ab Pharmaceutical emulsion
SE9804002D0 (sv) 1998-11-23 1998-11-23 Astra Ab New manufacturing process
JP2000247883A (ja) * 1999-02-23 2000-09-12 Fujisawa Pharmaceut Co Ltd ジヒドロピリジン系化合物を含有する内服用液剤
US20030102246A1 (en) * 1999-03-20 2003-06-05 Lts Lohmann Therapie-Systeme Ag Method for improving the stability of stored and/or used light-sensitive therapeutic systems or components thereof
US6956048B2 (en) * 1999-03-31 2005-10-18 Pharmacia & Upjohn Company Pharmaceutical emulsions for retroviral protease inhibitors
US6680334B2 (en) * 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
JP2003104888A (ja) * 2001-09-28 2003-04-09 Taiyo Yakuhin Kogyo Kk ジヒドロピリジン誘導体の錠剤
DE10224612A1 (de) * 2002-06-04 2003-12-24 Lohmann Therapie Syst Lts Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung
ATE375349T1 (de) * 2002-08-02 2007-10-15 Merck & Co Inc Substituierte furo(2,3-b)pyridin derivate
WO2004110368A2 (en) * 2003-06-06 2004-12-23 Merck & Co., Inc. Combination therapy for the treatment of hypertension
TW200613275A (en) * 2004-08-24 2006-05-01 Recordati Ireland Ltd Lercanidipine salts
US20080095841A1 (en) * 2004-10-06 2008-04-24 Eisai R&D Management Co., Ltd. Pharmaceutical Composition, Method for Producing the Same, and Method for Stabilizing Dihydropyridine Compound in the Pharmaceutical Composition
US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
CA2616806A1 (en) * 2005-07-28 2007-02-08 Reliant Pharmaceuticals, Inc. Treatment with dihydropyridine calcium channel blockers and omega-3 fatty acids and a combination product thereof
MX2008013405A (es) * 2006-04-18 2009-03-09 Ekr Therapeutics Inc Composiciones farmaceuticas premezcladas listas para uso.

Also Published As

Publication number Publication date
PT2320739T (pt) 2020-02-18
JP2011529879A (ja) 2011-12-15
HRP20200136T1 (hr) 2020-08-21
AU2009277100B2 (en) 2015-05-28
BRPI0917562B1 (pt) 2021-04-06
LT2320739T (lt) 2020-01-27
US20190117660A1 (en) 2019-04-25
US20100105743A1 (en) 2010-04-29
US20230302002A1 (en) 2023-09-28
SI2320739T1 (sl) 2020-03-31
AU2009277100A1 (en) 2010-02-04
KR101946977B1 (ko) 2019-05-21
JP2015098472A (ja) 2015-05-28
CY1122526T1 (el) 2021-01-27
EP2320739B1 (en) 2019-11-27
DK2320739T3 (da) 2020-02-24
EP2320739A1 (en) 2011-05-18
ES2770178T3 (es) 2020-06-30
CN106377501A (zh) 2017-02-08
KR20170051542A (ko) 2017-05-11
WO2010014234A1 (en) 2010-02-04
BRPI0917562A8 (pt) 2017-12-12
HUE047692T2 (hu) 2020-05-28
BRPI0917562A2 (pt) 2017-06-20
US20120322836A1 (en) 2012-12-20
JP2016216501A (ja) 2016-12-22
CA2732692C (en) 2019-12-24
CN102186351A (zh) 2011-09-14
EP2320739A4 (en) 2011-08-24
EA201170287A1 (ru) 2011-10-31
KR20180059956A (ko) 2018-06-05
CA2732692A1 (en) 2010-02-04
JP6537538B2 (ja) 2019-07-03
BRPI0917562B8 (pt) 2021-05-25
KR20160095206A (ko) 2016-08-10
MX2011001241A (es) 2011-08-03
JP2017081980A (ja) 2017-05-18
NZ591204A (en) 2013-02-22
KR20110059843A (ko) 2011-06-07

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