PL2280961T3 - Związki 1,5-difenylo-pirolidyn-2-onu jako ligandy CB-1 - Google Patents

Związki 1,5-difenylo-pirolidyn-2-onu jako ligandy CB-1

Info

Publication number
PL2280961T3
PL2280961T3 PL09734415T PL09734415T PL2280961T3 PL 2280961 T3 PL2280961 T3 PL 2280961T3 PL 09734415 T PL09734415 T PL 09734415T PL 09734415 T PL09734415 T PL 09734415T PL 2280961 T3 PL2280961 T3 PL 2280961T3
Authority
PL
Poland
Prior art keywords
pyrrolidin
ligands
diphenyl
compounds
Prior art date
Application number
PL09734415T
Other languages
English (en)
Inventor
John Mehnert Schaus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL2280961T3 publication Critical patent/PL2280961T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL09734415T 2008-04-22 2009-04-02 Związki 1,5-difenylo-pirolidyn-2-onu jako ligandy CB-1 PL2280961T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4694308P 2008-04-22 2008-04-22
EP09734415A EP2280961B1 (en) 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-one compounds as cb-1 ligands
PCT/US2009/039293 WO2009131815A1 (en) 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-one compounds as cb-1 ligands

Publications (1)

Publication Number Publication Date
PL2280961T3 true PL2280961T3 (pl) 2012-12-31

Family

ID=40600096

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09734415T PL2280961T3 (pl) 2008-04-22 2009-04-02 Związki 1,5-difenylo-pirolidyn-2-onu jako ligandy CB-1

Country Status (17)

Country Link
US (1) US8420654B2 (pl)
EP (1) EP2280961B1 (pl)
JP (1) JP5539323B2 (pl)
KR (1) KR101283803B1 (pl)
CN (1) CN102007121B (pl)
AU (1) AU2009238445B2 (pl)
BR (1) BRPI0910775A2 (pl)
CA (1) CA2721542C (pl)
DK (1) DK2280961T3 (pl)
EA (1) EA019067B1 (pl)
ES (1) ES2390560T3 (pl)
HR (1) HRP20120680T1 (pl)
MX (1) MX2010011547A (pl)
PL (1) PL2280961T3 (pl)
PT (1) PT2280961E (pl)
SI (1) SI2280961T1 (pl)
WO (1) WO2009131815A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ534757A (en) * 2002-03-12 2006-07-28 Merck & Co Inc Substituted amides
TW200533657A (en) 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
ES2315851T3 (es) 2004-02-19 2009-04-01 Solvay Pharmaceuticals B.V. Derivados de imidazolina que tienen actividad antagonista cb1.
WO2007020502A2 (en) 2005-08-16 2007-02-22 Pharmacia & Upjohn Company Llc Cannabinoid receptor ligands and uses thereof
JP5269795B2 (ja) * 2006-09-29 2013-08-21 グリーン・クロス・コーポレイション カンナビノイドｃｂ１受容体アンタゴニストとしてのヘテロアリール−ピラゾール誘導体
PE20080926A1 (es) * 2006-10-23 2008-07-19 Lilly Co Eli Compuestos cb1

Also Published As

Publication number Publication date
KR101283803B1 (ko) 2013-07-15
KR20100124342A (ko) 2010-11-26
AU2009238445B2 (en) 2013-09-26
AU2009238445A1 (en) 2009-10-29
CN102007121B (zh) 2013-08-14
CA2721542C (en) 2016-03-29
CA2721542A1 (en) 2009-10-29
CN102007121A (zh) 2011-04-06
ES2390560T3 (es) 2012-11-14
EA019067B1 (ru) 2013-12-30
JP5539323B2 (ja) 2014-07-02
JP2011518220A (ja) 2011-06-23
EP2280961A1 (en) 2011-02-09
EA201071223A1 (ru) 2011-04-29
WO2009131815A1 (en) 2009-10-29
DK2280961T3 (da) 2012-08-27
MX2010011547A (es) 2010-11-09
BRPI0910775A2 (pt) 2015-09-29
US8420654B2 (en) 2013-04-16
US20110034484A1 (en) 2011-02-10
PT2280961E (pt) 2012-09-10
HRP20120680T1 (hr) 2012-10-31
SI2280961T1 (sl) 2012-11-30
EP2280961B1 (en) 2012-07-25

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