PL2152735T3 - Sposób wytwarzania dojrzałego VWF z propeptydu - Google Patents

Sposób wytwarzania dojrzałego VWF z propeptydu

Info

Publication number
PL2152735T3
PL2152735T3 PL08754504T PL08754504T PL2152735T3 PL 2152735 T3 PL2152735 T3 PL 2152735T3 PL 08754504 T PL08754504 T PL 08754504T PL 08754504 T PL08754504 T PL 08754504T PL 2152735 T3 PL2152735 T3 PL 2152735T3
Authority
PL
Poland
Prior art keywords
vwf
peptide
pro
producing mature
producing
Prior art date
Application number
PL08754504T
Other languages
English (en)
Inventor
Wolfgang Mundt
Artur Mitterer
Meinhard Hasslacher
Christa Mayer
Original Assignee
Baxalta Inc
Baxalta GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta Inc, Baxalta GmbH filed Critical Baxalta Inc
Publication of PL2152735T3 publication Critical patent/PL2152735T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08754504T 2007-05-18 2008-05-16 Sposób wytwarzania dojrzałego VWF z propeptydu PL2152735T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93089107P 2007-05-18 2007-05-18
EP08754504.2A EP2152735B1 (en) 2007-05-18 2008-05-16 Method for producing mature vwf from vwf pro-peptide
PCT/US2008/006291 WO2008143977A1 (en) 2007-05-18 2008-05-16 Method for producing mature vwf from vwf pro-peptide

Publications (1)

Publication Number Publication Date
PL2152735T3 true PL2152735T3 (pl) 2015-08-31

Family

ID=39666205

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08754504T PL2152735T3 (pl) 2007-05-18 2008-05-16 Sposób wytwarzania dojrzałego VWF z propeptydu

Country Status (17)

Country Link
US (1) US8058411B2 (pl)
EP (1) EP2152735B1 (pl)
JP (2) JP5053435B2 (pl)
KR (1) KR101156263B1 (pl)
CN (1) CN101679496B (pl)
AU (1) AU2008254522B2 (pl)
BR (1) BRPI0811649B8 (pl)
CA (1) CA2684151A1 (pl)
DK (1) DK2152735T3 (pl)
ES (1) ES2539284T3 (pl)
HK (1) HK1144577A1 (pl)
HU (1) HUE025257T2 (pl)
MX (1) MX2009012387A (pl)
NZ (1) NZ581582A (pl)
PL (1) PL2152735T3 (pl)
PT (1) PT2152735E (pl)
WO (1) WO2008143977A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012082933A1 (en) * 2010-12-15 2012-06-21 Baxter International, Inc. Eluate collection using conductivity gradient
US20140276101A1 (en) * 2013-03-14 2014-09-18 Boston Scientific Scimed, Inc. Medical device for detecting a target and related methods of use
AR102048A1 (es) * 2014-08-12 2017-02-01 Baxalta Inc Producción del factor x completamente procesado y funcional en un sistema de expresión de mamífero de secreción de furina
CA3068121A1 (en) 2017-06-23 2018-12-27 Baxalta Incorporated Purification of factor viii subspecies
JP2021519280A (ja) 2018-03-21 2021-08-10 バクスアルタ インコーポレイテッド クロマトグラフィー法によるvwfとvwfプロペプチドの分離

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
AT407750B (de) 1999-02-19 2001-05-25 Immuno Ag Verfahren zur herstellung einer vwf-präparation
ES2434035T3 (es) * 2004-12-27 2013-12-13 Baxter International Inc. Conjugados de polímero-factor von Willebrand

Also Published As

Publication number Publication date
DK2152735T3 (en) 2015-04-20
AU2008254522A1 (en) 2008-11-27
JP5053435B2 (ja) 2012-10-17
KR101156263B1 (ko) 2012-06-13
JP2012210226A (ja) 2012-11-01
US8058411B2 (en) 2011-11-15
JP2010527588A (ja) 2010-08-19
CN101679496B (zh) 2013-03-13
HUE025257T2 (en) 2016-03-29
HK1144577A1 (en) 2011-02-25
NZ581582A (en) 2012-02-24
PT2152735E (pt) 2015-07-21
KR20100028042A (ko) 2010-03-11
ES2539284T3 (es) 2015-06-29
BRPI0811649B1 (pt) 2020-11-17
AU2008254522A2 (en) 2010-02-18
EP2152735B1 (en) 2015-03-18
EP2152735A1 (en) 2010-02-17
MX2009012387A (es) 2010-02-10
BRPI0811649B8 (pt) 2021-05-25
CA2684151A1 (en) 2008-11-27
US20090029918A1 (en) 2009-01-29
AU2008254522B2 (en) 2012-07-12
BRPI0811649A2 (pt) 2014-11-11
WO2008143977A1 (en) 2008-11-27
CN101679496A (zh) 2010-03-24

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