PL1718651T3 - Pochodne 7H-pirolopirymidyny - Google Patents

Pochodne 7H-pirolopirymidyny

Info

Publication number
PL1718651T3
PL1718651T3 PL05715376T PL05715376T PL1718651T3 PL 1718651 T3 PL1718651 T3 PL 1718651T3 PL 05715376 T PL05715376 T PL 05715376T PL 05715376 T PL05715376 T PL 05715376T PL 1718651 T3 PL1718651 T3 PL 1718651T3
Authority
PL
Poland
Prior art keywords
derivatives
preparation
pharmaceutical compositions
pyrrolopyrimidine derivatives
pyrrolo
Prior art date
Application number
PL05715376T
Other languages
English (en)
Inventor
Giorgio Caravatti
Andrea Vaupel
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL1718651T3 publication Critical patent/PL1718651T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL05715376T 2004-02-18 2005-02-17 Pochodne 7H-pirolopirymidyny PL1718651T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0403606.7A GB0403606D0 (en) 2004-02-18 2004-02-18 Organic compounds
PCT/EP2005/001635 WO2005077951A2 (en) 2004-02-18 2005-02-17 7h-pyrrolopyrimidine derivatives
EP05715376A EP1718651B1 (en) 2004-02-18 2005-02-17 7h-pyrrolopyrimidine derivatives

Publications (1)

Publication Number Publication Date
PL1718651T3 true PL1718651T3 (pl) 2009-09-30

Family

ID=32039961

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05715376T PL1718651T3 (pl) 2004-02-18 2005-02-17 Pochodne 7H-pirolopirymidyny

Country Status (16)

Country Link
US (1) US7625894B2 (pl)
EP (1) EP1718651B1 (pl)
JP (1) JP2007523115A (pl)
KR (1) KR20060124705A (pl)
CN (1) CN1922184A (pl)
AT (1) ATE429435T1 (pl)
AU (1) AU2005212832B2 (pl)
BR (1) BRPI0507811A (pl)
CA (1) CA2553889A1 (pl)
DE (1) DE602005014087D1 (pl)
ES (1) ES2322814T3 (pl)
GB (1) GB0403606D0 (pl)
PL (1) PL1718651T3 (pl)
PT (1) PT1718651E (pl)
RU (1) RU2006133264A (pl)
WO (1) WO2005077951A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010006457A (es) 2007-12-19 2010-07-05 Amgen Inc Compuestos fusionados de piridina, pirimidina y triazina como inhibidores de ciclo celular.
US8389533B2 (en) 2008-04-07 2013-03-05 Amgen Inc. Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors
MY161199A (en) 2011-03-23 2017-04-14 Amgen Inc Fused tricyclic dual inhibitors of cdk 4/6 and flt3
MX2015002887A (es) 2012-09-06 2015-07-06 Plexxikon Inc Compuestos y metodos para la modulacion de cinasas, e indicaciones para ello.
CA2902755C (en) * 2013-03-11 2021-02-16 Merck Patent Gmbh 6-[4-(1h-imidazol-2-yl)piperidin-1-yl]pyrimidin-4-amine derivatives as modulators of kinase activity
WO2014145576A2 (en) 2013-03-15 2014-09-18 Northwestern University Substituted pyrrolo(2,3-d)pyrimidines for the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1441497A (en) * 1996-01-23 1997-08-20 Novartis Ag Pyrrolopyrimidines and processes for their preparation
PT938486E (pt) * 1996-08-23 2008-03-27 Novartis Ag Pirrolopirimidinas substituídas e processos para a sua preparação
PT970084E (pt) * 1997-03-19 2003-10-31 Abbott Gmbh & Co Kg Pirrolo¬2,3d|pirimidinas e sua utilizacao como inibidores da tirosina-cinase
PA8474101A1 (es) * 1998-06-19 2000-09-29 Pfizer Prod Inc Compuestos de pirrolo [2,3-d] pirimidina
GB0119249D0 (en) * 2001-08-07 2001-10-03 Novartis Ag Organic compounds
EP1441736A2 (en) * 2001-10-29 2004-08-04 Novartis AG Use of 7h-pyrrolo[2,3-d]pyrimidine derivatives in the treatment of solid tumor diseases
US7253166B2 (en) * 2003-04-22 2007-08-07 Irm Llc 6-phenyl-7H-pyrrolo[2,3-d]pyrimidine compounds that induce neuronal differentiation in embryonic stem cells
WO2005069865A2 (en) * 2004-01-13 2005-08-04 Ambit Biosciences Corporation Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
PE20051092A1 (es) * 2004-01-29 2006-01-20 Novartis Ag Derivados de pirrolo-pirimidina utiles para el tratamiento de enfermedades proliferativas

Also Published As

Publication number Publication date
GB0403606D0 (en) 2004-03-24
PT1718651E (pt) 2009-07-17
AU2005212832B2 (en) 2009-11-05
CN1922184A (zh) 2007-02-28
US7625894B2 (en) 2009-12-01
WO2005077951A3 (en) 2006-03-02
ATE429435T1 (de) 2009-05-15
WO2005077951A2 (en) 2005-08-25
BRPI0507811A (pt) 2007-07-10
EP1718651A2 (en) 2006-11-08
US20070135460A1 (en) 2007-06-14
KR20060124705A (ko) 2006-12-05
DE602005014087D1 (de) 2009-06-04
AU2005212832A1 (en) 2005-08-25
RU2006133264A (ru) 2008-04-10
CA2553889A1 (en) 2005-08-25
EP1718651B1 (en) 2009-04-22
JP2007523115A (ja) 2007-08-16
ES2322814T3 (es) 2009-06-29

Similar Documents

Publication Publication Date Title
HK1065483A1 (en) 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives
NZ543661A (en) Pyrazolo-quinazoline derivatives having antitumor activity and process for their preparation
GB0022438D0 (en) Organic Compounds
GB0215844D0 (en) Organic compounds
TW200615266A (en) Organic compounds
EP1633740A4 (en) CHEMICAL COMPOUNDS
TW200722081A (en) New therapeutic combinations for the treatment or prevention of depression
TW200633964A (en) Tetralin and indane derivatives and uses thereof
TW200502230A (en) Dual nk1/nk3 derivatives
TW200639156A (en) New compounds
TW200510392A (en) Chemical compounds
MY135850A (en) Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
TNSN07440A1 (en) Derivatives of pyrido [2,3 -d] pyrimidine, the preparation thereof, and the therapeutic application of the same
EP1812112A4 (en) CHEMICAL COMPOUNDS
TW200505452A (en) Chemical compounds
PT1869038E (pt) Compostos de 5,6,7,8-tetra-hidro-imidazo[1,2-a]piridin-2- ilamina substituída e sua utilização para produzir fármacos
PL1718651T3 (pl) Pochodne 7H-pirolopirymidyny
TW200626581A (en) Compounds, compositions containing them, preparation thereof and uses thereof
GEP20105095B (en) Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents
ZA201000581B (en) 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide and 2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]-diazepine-7-carboxamide derivatives,preparation and therapeutic use thereof
WO2003080617A8 (en) Pyrazolopyrimidine derivatives
TW200510370A (en) Urea derivatives
WO2007043094A3 (en) 6-vinyl pyrimidine and pyrimidinone derivatives and the use thereof
ZA200605653B (en) Proline derivatives used as pharmaceutical active ingredients for the treatment of tumours
TW200621750A (en) Compounds, compositions containing them, preparation thereof and uses thereof