PL164909B1 - Sposób wytwarzania nowych pochodnych izolndolonu PL PL - Google Patents

Sposób wytwarzania nowych pochodnych izolndolonu PL PL

Info

Publication number: PL164909B1
Authority: PL; Poland
Prior art keywords: kpa; solution; evaporated; 3ars; 7ars
Prior art date: 1989-11-23

Application number

PL90287910A

Other languages

English (en)

Polish (pl)

Inventor

Marie-Christine Dubroeucq

Claude Moutonnier

Jean-Francois Peyronel

Michel Tabart

Alain Truchon

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-23

Filing date

1990-11-23

Publication date

1994-10-31

1990-11-23 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1994-10-31 Publication of PL164909B1 publication Critical patent/PL164909B1/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Transplantation (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL90287910A 1989-11-23 1990-11-23 Sposób wytwarzania nowych pochodnych izolndolonu PL PL PL164909B1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8915406A FR2654725B1 (fr)	1989-11-23	1989-11-23	Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
PL164909B1 true PL164909B1 (pl)	1994-10-31

Family

ID=9387707

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
PL90292279A PL164892B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych izoindolonu PL PL
PL90292280A PL164904B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych Izoindolonu PL PL
PL90287910A PL164909B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych izolndolonu PL PL
PL90292278A PL164900B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych izolndolonu PL PL

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
PL90292279A PL164892B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych izoindolonu PL PL
PL90292280A PL164904B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych Izoindolonu PL PL

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL90292278A PL164900B1 (pl)	1989-11-23	1990-11-23	Sposób wytwarzania nowych pochodnych izolndolonu PL PL

Country Status (23)

Country	Link
US (1)	US5102667A (fr)
EP (1)	EP0429366B1 (fr)
JP (1)	JPH03176469A (fr)
KR (1)	KR910009659A (fr)
AT (1)	ATE102923T1 (fr)
AU (1)	AU635361B2 (fr)
CA (1)	CA2030569A1 (fr)
DE (1)	DE69007429T2 (fr)
DK (1)	DK0429366T3 (fr)
ES (1)	ES2062460T3 (fr)
FI (1)	FI905769A (fr)
FR (1)	FR2654725B1 (fr)
HU (1)	HUT56064A (fr)
IE (1)	IE904235A1 (fr)
IL (1)	IL96446A0 (fr)
NO (1)	NO174387C (fr)
NZ (1)	NZ236176A (fr)
PL (4)	PL164892B1 (fr)
PT (1)	PT95982A (fr)
RU (1)	RU2012559C1 (fr)
TW (1)	TW218378B (fr)
YU (1)	YU223490A (fr)
ZA (1)	ZA909369B (fr)

Families Citing this family (75)

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FR2676443B1 (fr) *	1991-05-17	1993-08-06	Rhone Poulenc Rorer Sa	Nouveaux derives de perhydroisoindole et leur preparation.
FR2676442B1 (fr) *	1991-05-17	1993-08-06	Rhone Poulenc Rorer Sa	Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
MY110227A (en) *	1991-08-12	1998-03-31	Ciba Geigy Ag	1-acylpiperindine compounds.
EP0533280B2 (fr) *	1991-09-20	2004-12-01	Glaxo Group Limited	Nouvelle indication médicale pour les antagonistes des tachykinines
FR2688219B1 (fr)	1992-03-03	1994-07-08	Sanofi Elf	Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
FR2689888B1 (fr) *	1992-04-10	1994-06-10	Rhone Poulenc Rorer Sa	Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689889B1 (fr) *	1992-04-10	1994-06-10	Rhone Poulenc Rorer Sa	Nouveaux derives de perhydroisoindole, et leur preparation.
US5830854A (en) *	1992-12-14	1998-11-03	Merck Sharp & Dohme, Limited	Method of treating cystic fibrosis using a tachykinin receptor antagonist
GB9305718D0 (en) *	1993-03-19	1993-05-05	Glaxo Group Ltd	Medicaments
FR2703679B1 (fr) *	1993-04-05	1995-06-23	Rhone Poulenc Rorer Sa	Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
TW365603B (en) *	1993-07-30	1999-08-01	Rhone Poulenc Rorer Sa	Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
FR2709752B1 (fr) *	1993-07-30	1995-10-06	Rhone Poulenc Rorer Sa	Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710913B1 (fr) *	1993-10-07	1995-11-24	Rhone Poulenc Rorer Sa	Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710842B1 (fr) *	1993-10-07	1995-11-24	Rhone Poulenc Rorer Sa	Nouvelle application thérapeutique de dérivés de perhydroisoindole.
US6403577B1 (en) *	1993-11-17	2002-06-11	Eli Lilly And Company	Hexamethyleneiminyl tachykinin receptor antagonists
US6869957B1 (en)	1993-11-17	2005-03-22	Eli Lilly And Company	Non-peptide tachykinin receptor antagonists
US5589489A (en) *	1993-12-15	1996-12-31	Zeneca Limited	Cyclic amide derivatives for treating asthma
US6203803B1 (en)	1994-12-14	2001-03-20	Societe L'oreal S.A.	Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained
FR2719476B1 (fr) *	1994-05-05	1997-05-23	Oreal	Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue.
FR2719474B1 (fr)	1994-05-05	1996-05-31	Oreal	Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue.
US5491140A (en) *	1994-06-30	1996-02-13	Eli Lilly And Company	Naphthyl tachykinin receptor antagonists to treat physiological conditions
TW397825B (en) *	1994-10-14	2000-07-11	Novartis Ag	Aroyl-piperidine derivatives
FR2725900B1 (fr) *	1994-10-21	1997-07-18	Sanofi Sa	Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
FR2728165A1 (fr)	1994-12-19	1996-06-21	Oreal	Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr)	1994-12-19	1996-06-21	Oreal	Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr)	1994-12-19	1996-06-21	Oreal	Composition topique contenant un antagoniste de substance p
FR2741262B1 (fr)	1995-11-20	1999-03-05	Oreal	Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
US7019142B2 (en) *	1998-01-16	2006-03-28	Pfizer Inc.	Process for preparing naphthyridones and intermediates
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ATE550019T1 (de)	2005-05-17	2012-04-15	Merck Sharp & Dohme	Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
CN101495184A (zh)	2005-07-15	2009-07-29	Amr科技公司	芳基和杂芳基取代的四氢苯并氮杂及其在阻断去甲肾上腺素多巴胺和血清素的重摄取中的应用
GB0603041D0 (en)	2006-02-15	2006-03-29	Angeletti P Ist Richerche Bio	Therapeutic compounds
DE102006007882A1 (de)	2006-02-21	2007-08-30	Bayer Cropscience Ag	Cycloalkyl-phenylsubstituierte cyclische Ketoenole
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
US8071623B2 (en)	2007-01-10	2011-12-06	Instituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa	Amide substituted indazoles as poly(ADP-ribose)polymerase(PARP) inhibitors
WO2008090117A1 (fr)	2007-01-24	2008-07-31	Glaxo Group Limited	Nouvelles compositions pharmaceutiques
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US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
UA105182C2 (ru)	2008-07-03	2014-04-25	Ньюрексон, Інк.	Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
WO2010114780A1 (fr)	2009-04-01	2010-10-07	Merck Sharp & Dohme Corp.	Inhibiteurs de l'activité akt
DK2429296T3 (en)	2009-05-12	2018-03-12	Albany Molecular Res Inc	7 - ([1,2,4,] TRIAZOLO [1,5, -A] PYRIDIN-6-YL) -4- (3,4-DICHLORPHENYL) -1,2,3,4- TETRAHYDROISOQUINOLINE AND USE thereof
JP5739415B2 (ja)	2009-05-12	2015-06-24	ブリストル−マイヤーズスクウィブカンパニー	（Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用
ES2446971T3 (es)	2009-05-12	2014-03-11	Albany Molecular Research, Inc.	Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
BR112012008849A2 (pt)	2009-10-14	2015-09-22	Schering Corp	composto, composição farmacêutica, e, uso de um composto
CN103068980B (zh)	2010-08-02	2017-04-05	瑟纳治疗公司	使用短干扰核酸（siNA）的RNA干扰介导的联蛋白（钙粘蛋白关联蛋白质），β1（CTNNB1）基因表达的抑制
JP2013537423A (ja)	2010-08-17	2013-10-03	メルク・シャープ・エンド・ドーム・コーポレイション	低分子干渉核酸（ｓｉＮＡ）を用いたＢ型肝炎ウイルス（ＨＢＶ）遺伝子発現のＲＮＡ干渉媒介性阻害
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WO2012030685A2 (fr)	2010-09-01	2012-03-08	Schering Corporation	Dérivés d'indazole utilisables en tant qu'inhibiteurs de la voie erk
WO2012036997A1 (fr)	2010-09-16	2012-03-22	Schering Corporation	Dérivés condensés de pyrazole utilisés comme nouveaux inhibiteurs erk
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WO2012087772A1 (fr)	2010-12-21	2012-06-28	Schering Corporation	Dérivés d'indazole utiles en tant qu'inhibiteurs de erk
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ES2672099T3 (es)	2011-07-04	2018-06-12	Irbm - Science Park S.P.A.	Antagonistas del receptor NK-1 para el tratamiento de la neovascularización corneal
US9023865B2 (en)	2011-10-27	2015-05-05	Merck Sharp & Dohme Corp.	Compounds that are ERK inhibitors
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PT2925888T (pt)	2012-11-28	2017-12-13	Merck Sharp & Dohme	Composições e métodos para tratamento do cancro
KR102196882B1 (ko)	2012-12-20	2020-12-30	머크 샤프 앤드 돔 코포레이션	Hdm2 억제제로서의 치환된 이미다조피리딘
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WO2018071283A1 (fr)	2016-10-12	2018-04-19	Merck Sharp & Dohme Corp.	Inhibiteurs de kdm5
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WO2019162519A1 (fr)	2018-02-26	2019-08-29	Ospedale San Raffaele S.R.L.	Antagonistes nk-1 destinés à être utilisés dans le traitement de la douleur oculaire
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE792374A (fr) *	1971-12-08	1973-06-06	Allen & Hanburys Ltd	Nouveaux derives d'isoindoline
US4042707A (en) *	1976-02-19	1977-08-16	E. I. Du Pont De Nemours And Company	3α-Arylhydroisoindoles

1989
- 1989-11-23 FR FR8915406A patent/FR2654725B1/fr not_active Expired - Lifetime
1990
- 1990-11-20 US US07/616,262 patent/US5102667A/en not_active Expired - Fee Related
- 1990-11-21 NZ NZ236176A patent/NZ236176A/xx unknown
- 1990-11-22 AU AU66838/90A patent/AU635361B2/en not_active Ceased
- 1990-11-22 HU HU907250A patent/HUT56064A/hu unknown
- 1990-11-22 CA CA002030569A patent/CA2030569A1/fr not_active Abandoned
- 1990-11-22 FI FI905769A patent/FI905769A/fi not_active IP Right Cessation
- 1990-11-22 NO NO905066A patent/NO174387C/no unknown
- 1990-11-22 RU SU904831707A patent/RU2012559C1/ru active
- 1990-11-22 DK DK90403299.2T patent/DK0429366T3/da active
- 1990-11-22 TW TW079109874A patent/TW218378B/zh active
- 1990-11-22 DE DE69007429T patent/DE69007429T2/de not_active Expired - Fee Related
- 1990-11-22 ES ES90403299T patent/ES2062460T3/es not_active Expired - Lifetime
- 1990-11-22 IE IE423590A patent/IE904235A1/en unknown
- 1990-11-22 AT AT90403299T patent/ATE102923T1/de not_active IP Right Cessation
- 1990-11-22 JP JP2320571A patent/JPH03176469A/ja active Pending
- 1990-11-22 EP EP90403299A patent/EP0429366B1/fr not_active Expired - Lifetime
- 1990-11-22 ZA ZA909369A patent/ZA909369B/xx unknown
- 1990-11-22 IL IL96446A patent/IL96446A0/xx unknown
- 1990-11-22 KR KR1019900019098A patent/KR910009659A/ko not_active Application Discontinuation
- 1990-11-23 PL PL90292279A patent/PL164892B1/pl unknown
- 1990-11-23 PL PL90292280A patent/PL164904B1/pl unknown
- 1990-11-23 PL PL90287910A patent/PL164909B1/pl unknown
- 1990-11-23 PT PT95982A patent/PT95982A/pt not_active Application Discontinuation
- 1990-11-23 PL PL90292278A patent/PL164900B1/pl unknown
- 1990-11-23 YU YU223490A patent/YU223490A/sh unknown

Also Published As

Publication number	Publication date
EP0429366A1 (fr)	1991-05-29
DE69007429T2 (de)	1994-07-07
PL164892B1 (pl)	1994-10-31
AU6683890A (en)	1991-05-30
PT95982A (pt)	1991-09-13
IL96446A0 (en)	1991-08-16
AU635361B2 (en)	1993-03-18
NO905066D0 (no)	1990-11-22
NZ236176A (en)	1993-05-26
IE904235A1 (en)	1991-06-05
EP0429366B1 (fr)	1994-03-16
PL164900B1 (pl)	1994-10-31
KR910009659A (ko)	1991-06-28
NO905066L (no)	1991-05-24
PL292280A1 (en)	1992-06-01
JPH03176469A (ja)	1991-07-31
CA2030569A1 (fr)	1991-05-24
ATE102923T1 (de)	1994-04-15
HU907250D0 (en)	1991-05-28
ZA909369B (en)	1991-10-30
HUT56064A (en)	1991-07-29
FR2654725A1 (fr)	1991-05-24
RU2012559C1 (ru)	1994-05-15
PL292278A1 (en)	1992-06-01
YU223490A (sh)	1993-05-28
DE69007429D1 (de)	1994-04-21
FR2654725B1 (fr)	1992-02-14
FI905769A (fi)	1991-05-24
NO174387C (no)	1994-04-27
US5102667A (en)	1992-04-07
TW218378B (fr)	1994-01-01
NO174387B (no)	1994-01-17
PL292279A1 (en)	1992-06-01
PL164904B1 (pl)	1994-10-31
ES2062460T3 (es)	1994-12-16
FI905769A0 (fi)	1990-11-22
DK0429366T3 (da)	1994-06-27

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