PH21444A - Erythro-(e)-7-(3'-c1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept- 6-enoic acids and derivatives thereof - Google Patents

Erythro-(e)-7-(3'-c1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept- 6-enoic acids and derivatives thereof

Info

Publication number: PH21444A
Authority: PH; Philippines
Prior art keywords: dihydroxyhept; 3alkyl; erythro; naphth; dimethylphenyl
Prior art date: 1984-07-24

Application number

PH32550A

Other languages

English (en)

Inventor

Paul L Anderson

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-24

Filing date

1985-07-22

Publication date

1987-10-20

1985-07-22 Application filed by Sandoz Ag filed Critical Sandoz Ag

1987-10-20 Publication of PH21444A publication Critical patent/PH21444A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
- C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Obesity (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pyrane Compounds (AREA)

PH32550A 1984-07-24 1985-07-22 Erythro-(e)-7-(3'-c1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept- 6-enoic acids and derivatives thereof PH21444A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US63380984A	1984-07-24	1984-07-24

Publications (1)

Publication Number	Publication Date
PH21444A true PH21444A (en)	1987-10-20

Family

ID=24541204

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH32550A PH21444A (en)	1984-07-24	1985-07-22	Erythro-(e)-7-(3'-c1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept- 6-enoic acids and derivatives thereof

Country Status (21)

Country	Link
JP (1)	JPS6137754A (it)
KR (1)	KR860001045A (it)
AU (1)	AU4522685A (it)
BE (1)	BE902914A (it)
DE (1)	DE3525256A1 (it)
DK (1)	DK333785A (it)
ES (1)	ES8705356A1 (it)
FI (1)	FI852851L (it)
FR (1)	FR2568248A1 (it)
GB (1)	GB2162179A (it)
GR (1)	GR851805B (it)
HU (1)	HUT39142A (it)
IL (1)	IL75874A0 (it)
IT (1)	IT1200095B (it)
LU (1)	LU86012A1 (it)
NL (1)	NL8502010A (it)
PH (1)	PH21444A (it)
PL (1)	PL254654A1 (it)
PT (1)	PT80845B (it)
SE (1)	SE8503556L (it)
ZA (1)	ZA855594B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4904646A (en) *	1987-05-22	1990-02-27	E. R. Squibb & Sons, Inc.	Phosphorus-containing HMG-COA reductase inhibitors
US5091378A (en) *	1987-05-22	1992-02-25	E. R. Squibb & Sons, Inc.	Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
DE3722807A1 (de) *	1987-07-10	1989-01-19	Hoechst Ag	Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US4792614A (en) *	1987-08-05	1988-12-20	American Home Products Corporation	Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
US4812583A (en) *	1987-09-11	1989-03-14	American Home Products Corporation	Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
DE3818570A1 (de) *	1988-06-01	1989-12-21	Boehringer Mannheim Gmbh	Neue 6-substituierte-4-hydroxy-tetrahydro-pyran -2-on-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen
US5506219A (en) *	1988-08-29	1996-04-09	E. R. Squibb & Sons, Inc.	Pyridine anchors for HMG-CoA reductase inhibitors
CA2185961A1 (en) *	1996-09-19	1998-03-20	K.S. Keshava Murthy	Process for producing simvastatin
US20010006644A1 (en)	1997-07-31	2001-07-05	David J. Bova	Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
KR100836960B1 (ko)	2007-09-07	2008-06-10	주식회사 서울제약	새로운 나이아신 제어방출형 제제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55132595A (en) *	1979-04-04	1980-10-15	Nec Corp	Semiconductor circuit

1985
- 1985-07-12 NL NL8502010A patent/NL8502010A/nl not_active Application Discontinuation
- 1985-07-12 HU HU852696A patent/HUT39142A/hu unknown
- 1985-07-15 DE DE19853525256 patent/DE3525256A1/de not_active Withdrawn
- 1985-07-16 FR FR8510988A patent/FR2568248A1/fr active Pending
- 1985-07-17 BE BE1/011302A patent/BE902914A/fr not_active IP Right Cessation
- 1985-07-22 GB GB08518490A patent/GB2162179A/en not_active Withdrawn
- 1985-07-22 PH PH32550A patent/PH21444A/en unknown
- 1985-07-22 FI FI852851A patent/FI852851L/fi not_active Application Discontinuation
- 1985-07-22 KR KR1019850005206A patent/KR860001045A/ko not_active Application Discontinuation
- 1985-07-22 IL IL75874A patent/IL75874A0/xx unknown
- 1985-07-22 AU AU45226/85A patent/AU4522685A/en not_active Abandoned
- 1985-07-22 GR GR851805A patent/GR851805B/el unknown
- 1985-07-22 ES ES545454A patent/ES8705356A1/es not_active Expired
- 1985-07-22 LU LU86012A patent/LU86012A1/fr unknown
- 1985-07-22 DK DK333785A patent/DK333785A/da not_active Application Discontinuation
- 1985-07-22 PT PT80845A patent/PT80845B/pt unknown
- 1985-07-22 SE SE8503556A patent/SE8503556L/xx not_active Application Discontinuation
- 1985-07-23 IT IT8548385A patent/IT1200095B/it active
- 1985-07-23 JP JP16278685A patent/JPS6137754A/ja active Pending
- 1985-07-23 PL PL25465485A patent/PL254654A1/xx unknown
- 1985-07-24 ZA ZA855594A patent/ZA855594B/xx unknown

Also Published As

Publication number	Publication date
LU86012A1 (fr)	1986-02-12
SE8503556L (sv)	1986-01-25
JPS6137754A (ja)	1986-02-22
DK333785A (da)	1986-01-25
ES8705356A1 (es)	1987-05-01
PT80845B (en)	1987-03-24
PT80845A (en)	1985-08-01
IT1200095B (it)	1989-01-05
GR851805B (it)	1985-11-26
IL75874A0 (en)	1985-11-29
FR2568248A1 (fr)	1986-01-31
PL254654A1 (en)	1986-08-26
IT8548385A0 (it)	1985-07-23
GB8518490D0 (en)	1985-08-29
AU4522685A (en)	1986-01-30
DE3525256A1 (de)	1986-01-30
ES545454A0 (es)	1987-05-01
NL8502010A (nl)	1986-02-17
FI852851A0 (fi)	1985-07-22
KR860001045A (ko)	1986-02-22
BE902914A (fr)	1986-01-17
FI852851L (fi)	1986-01-25
DK333785D0 (da)	1985-07-22
GB2162179A (en)	1986-01-29
HUT39142A (en)	1986-08-28
SE8503556D0 (sv)	1985-07-22
ZA855594B (en)	1987-02-25

Publication	Publication Date	Title
DE3665456D1 (en)	1989-10-12	Pyrimidine derivatives
GR3001555T3 (en)	1992-11-23	4(4-oxo-1,4-dihydropyridin-1-yl)phenyl derivatives
GB2158825B (en)	1989-01-25	1,4-dihydro-4-oxonaphthyridine derivatives and salts thereof
DE3473875D1 (en)	1988-10-13	Pyrimidine derivatives, preparation thereof and use thereof
EP0257850A3 (en)	1989-08-23	Pyrimidine derivatives
EP0169712A3 (en)	1986-12-03	New pyrimidine derivatives, processes for preparation thereof and composition containing the same
PT84010A (en)	1987-01-01	Pyrimidine derivatives
PH21444A (en)	1987-10-20	Erythro-(e)-7-(3'-c1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept- 6-enoic acids and derivatives thereof
EP0177287A3 (en)	1986-11-26	Pyrimidine derivatives, processes for preparation thereof and composition of the same
IL74133A0 (en)	1985-04-30	Azolyl-aryl-alkanol derivatives,processes for their preparation and their use
ZA869588B (en)	1988-07-27	5,6-dialkoxy-4-imino-2(1h)quinazolinone derivatives
ZA864888B (en)	1988-02-24	5-substituted-6-aminopyrimidine derivatives,composition and uses
HK1003112A1 (en)	1998-10-09	5-fluorouracil derivatives
EP0150984A3 (en)	1985-08-21	6-(substituted) methylenepenicillanic and 6-(substituted) hydroxymethylpenicillanic acids and derivatives thereof
ZA85682B (en)	1986-09-24	6-(substituted)methylenepenicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof
GB8417852D0 (en)	1984-08-15	Pyrimidine derivatives
ZA865426B (en)	1988-02-24	Antihypertensive agents
ZA856886B (en)	1986-05-28	Antihypertensive derivatives
EP0166564A3 (en)	1986-10-29	Pyrimidone derivatives, preparation thereof and use thereof
ZA841839B (en)	1984-10-31	Pyrimidine derivatives,preparation thereof and use thereof
GB8706972D0 (en)	1987-04-29	5-fluorouracil derivatives
GB8618196D0 (en)	1986-09-03	Antihypertensive agents
GR861916B (en)	1986-11-27	Antihypertensive agents
GB8505286D0 (en)	1985-04-03	Quinoxaline derivatives
ZA855369B (en)	1986-06-25	New pyrimidine derivatives,processes for preparation thereof and composition containing the same