PE96999A1 - 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto - Google Patents

1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto

Info

Publication number
PE96999A1
PE96999A1 PE1998000626A PE00062698A PE96999A1 PE 96999 A1 PE96999 A1 PE 96999A1 PE 1998000626 A PE1998000626 A PE 1998000626A PE 00062698 A PE00062698 A PE 00062698A PE 96999 A1 PE96999 A1 PE 96999A1
Authority
PE
Peru
Prior art keywords
preparation
termodinamicamente
metoxifenoxi
carbazoliloxi
etilamino
Prior art date
Application number
PE1998000626A
Other languages
English (en)
Inventor
Erhard Reinholz
Peter Beyer
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of PE96999A1 publication Critical patent/PE96999A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA FORMA CRISTALINA (FORMA I) TERMODINAMICAMENTE ESTABLE DE CARVEDILOL LIBRE DE FORMAS DE SIMILARES CARACTERISTICAS FISICAS; CARACTERIZADA POR a)SU PATRON DE DIFRACCION DE RAYOS X, b)SU ESPECTRO INFRARROJO, b)SU PUNTO DE FUSION DE 123�C-126�C. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION Y AISLAMIENTO. EL CARVEDILOL PUEDE SER UTIL PARA LA PROFILAXIS O EL TRATAMIENTO DE ENFERMEDADES CIRCULATORIAS Y CARDIACAS
PE1998000626A 1997-07-22 1998-07-15 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto PE96999A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97112491A EP0893440A1 (en) 1997-07-22 1997-07-22 Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it

Publications (1)

Publication Number Publication Date
PE96999A1 true PE96999A1 (es) 1999-10-12

Family

ID=8227094

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998000626A PE96999A1 (es) 1997-07-22 1998-07-15 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto

Country Status (32)

Country Link
EP (2) EP0893440A1 (es)
JP (1) JP2001510824A (es)
KR (1) KR100336229B1 (es)
CN (1) CN1125047C (es)
AR (1) AR015133A1 (es)
AT (1) ATE236123T1 (es)
AU (1) AU740453B2 (es)
BR (1) BR9810776A (es)
CA (1) CA2296637C (es)
CZ (1) CZ296947B6 (es)
DE (1) DE69812964T2 (es)
DK (1) DK1000027T3 (es)
ES (1) ES2195366T3 (es)
HK (1) HK1029339A1 (es)
HR (1) HRP980406A2 (es)
HU (1) HUP0003198A3 (es)
IL (1) IL133677A (es)
MA (1) MA26523A1 (es)
MY (1) MY117734A (es)
NO (1) NO313588B1 (es)
NZ (1) NZ502136A (es)
PE (1) PE96999A1 (es)
PL (1) PL191602B1 (es)
PT (1) PT1000027E (es)
RU (1) RU2202542C2 (es)
SI (1) SI1000027T1 (es)
TR (1) TR200000148T2 (es)
TW (1) TW505631B (es)
UY (1) UY25108A1 (es)
WO (1) WO1999005105A1 (es)
YU (1) YU2200A (es)
ZA (1) ZA986475B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2227206T3 (es) * 2000-04-03 2005-04-01 F. Hoffmann-La Roche Ag Soluciones concentradas de carvedilol.
MXPA02012795A (es) 2000-06-28 2004-07-30 Teva Pharma Carvedilol.
EP1655285A1 (en) * 2000-06-28 2006-05-10 Teva Pharmaceutical Industries Ltd. Method for preparation of a crystalline form of carvedilol (form II)
ATE328595T1 (de) * 2001-07-13 2006-06-15 Smithkline Beecham Corp Carvedilolpolymorph
EP1929998A3 (en) 2001-09-21 2008-11-26 Egalet A/S Controlled release solid dispersions of carvedilol
ES2291503T3 (es) * 2001-09-28 2008-03-01 F. Hoffmann-La Roche Ag Formas pseudopolimorficas de carvedilol.
MXPA04006909A (es) 2002-01-15 2005-04-19 Teva Pharma Solidos cristalinos de carvedilol y procesos para su preparacion.
WO2003092622A2 (en) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
EP1539140A4 (en) * 2002-06-27 2005-12-07 Sb Pharmco Inc CARVEDILOLHYDOBROMID
BR0312102A (pt) * 2002-06-27 2007-05-29 Sb Pharmco Inc sais de fosfato de carvedilol e/ou seus solvatos, composições correspondentes, e/ou métodos de tratamento
EP1562552A1 (en) * 2002-11-08 2005-08-17 Egalet A/S Controlled release carvedilol compositions
EP1610767B1 (en) 2003-03-26 2011-01-19 Egalet A/S Morphine controlled release system
WO2004094378A1 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of carvedilol form-ii
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
JP2007512372A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール塩、対応する組成物、送達および／または治療方法
PT1838670E (pt) * 2004-12-09 2009-12-18 Zach System Spa Processo para a preparação de carvedilol e seus enantiómeros
US20070043099A1 (en) * 2005-06-09 2007-02-22 Igor Lifshitz Crystalline forms of carvedilol and processes for their preparation
US8022094B2 (en) 2006-06-28 2011-09-20 Teva Pharmaceutical Industries Ltd. Carvedilol phosphate
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
EP2155167A2 (en) 2007-06-04 2010-02-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
AU2010265213B2 (en) 2009-06-24 2012-08-23 Egalet Ltd. Controlled release formulations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
EP1000027B1 (en) 2003-04-02
HUP0003198A3 (en) 2002-10-28
AR015133A1 (es) 2001-04-18
ZA986475B (en) 2000-01-21
TW505631B (en) 2002-10-11
MY117734A (en) 2004-07-31
CA2296637A1 (en) 1999-02-04
CA2296637C (en) 2005-11-15
AU740453B2 (en) 2001-11-01
CZ2000221A3 (cs) 2000-05-17
BR9810776A (pt) 2000-09-19
DE69812964T2 (de) 2004-03-04
IL133677A0 (en) 2001-04-30
TR200000148T2 (tr) 2000-07-21
NZ502136A (en) 2002-05-31
HUP0003198A2 (en) 2001-03-28
PL338432A1 (en) 2000-11-06
IL133677A (en) 2004-06-01
CZ296947B6 (cs) 2006-08-16
PL191602B1 (pl) 2006-06-30
NO313588B1 (no) 2002-10-28
CN1125047C (zh) 2003-10-22
KR20010022097A (ko) 2001-03-15
MA26523A1 (fr) 2004-12-20
NO20000301L (no) 2000-01-21
NO20000301D0 (no) 2000-01-21
HRP980406A2 (en) 1999-04-30
YU2200A (sh) 2002-03-18
DE69812964D1 (de) 2003-05-08
EP1000027A1 (en) 2000-05-17
WO1999005105A1 (en) 1999-02-04
ES2195366T3 (es) 2003-12-01
JP2001510824A (ja) 2001-08-07
ATE236123T1 (de) 2003-04-15
KR100336229B1 (ko) 2002-05-09
UY25108A1 (es) 2000-12-29
DK1000027T3 (da) 2003-07-21
EP0893440A1 (en) 1999-01-27
CN1264366A (zh) 2000-08-23
PT1000027E (pt) 2003-07-31
RU2202542C2 (ru) 2003-04-20
AU8631998A (en) 1999-02-16
HK1029339A1 (en) 2001-03-30
SI1000027T1 (en) 2003-10-31

Similar Documents

Publication Publication Date Title
PE96999A1 (es) 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto
AR001332A1 (es) Nuevos compuestos antagonistas de la taquicinina, proceso para obtenerlos y composiciones farmaceuticas que los contienen.
NO20050664L (no) 2,4 substituerte indoler og anvendelse derav som 5-HT6 modulatorer
ES2123149T3 (es) Derivados de perhidroisoindol como antagonistas de la substancia p.
MX9204625A (es) Composicion farmaceutica para el tratamiento de una especie de mamifero, que sufre de deficiencia cardiaca congestiva.
IL56369A (en) Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
NO831084L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kvartaere dibenzotiepin-n-alkyl-norskopinetere
PA8426801A1 (es) Composiciones farmaceuticas para el tratamiento de la rinitis.
AR021843A1 (es) Derivados de propanolamina sustituidos con heterociclos, procedimiento para su preparacion, y su utilizacion.
NO164472C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive substituerte 2-(monokondenserte (3,4- og 5,6)-pyridylalkylensulfinyl)-benzimidazoler.
NO167204C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive diacylderivater av 4-(trialkylbenzyl)-piperazinylforbindelser.
ES2177024T3 (es) Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer.
ES2075454T3 (es) Forma cristalina pura de rifapentina.
DK246180A (da) Fremgangsmaade til fremstilling af paromomycinderivater
IL60567A (en) 2-dihalomethylene-3-halo-3-carbalk-oxy-5-oxopyrrolidines,process for their manufacture and their use as fungicidal,bactericidal and algicidal compositions
NO20004545D0 (no) FremgangsmÕte for fremstilling av (R)-<alfa>-(2,3- dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol
IL65493A (en) 2-(4-benzylpiperidino)-1-(4-halophenyl)-propan-1-ol derivatives,their preparation and pharmaceutical compositions containing them
DK0812320T3 (da) Amorft piretanid, polymorfe former deraf, fremgangsmåde til fremstilling deraf og deres anvendelse
NO870228D0 (no) Benzimidazolderivater, fremgangsmaate til deres fremstilling og anvendelse av forbindelsene fremstilt ved fremgangsmaaten.
IT8247871A0 (it) Derivati di carbammati, composizioni insetticide, acaricide o nematocide che li contengono e procedimento per la loro produzione ed applicazione
BG106078A (en) Thio-oxindole derivatives
AR011178A1 (es) Compuesto de sal de sodio de (acido (e) 4,6-dicloro-3-(2-oxo-1- fenilpirrolidin-3-ilideno-metil)-1h-indol-2-carboxilico en su forma hidratada,proceso para su preparacion, composicion farmaceutica que lo contiene y metodo de tratamiento utilizando dicho compuesto
AR013803A1 (es) Forma cristalina del acido (r)-3-[[(4-fluorfenil)sulfonil]amino]-1,2,3,4- tetrahidro-9h-carbazol-9-propanoico (ramatroban), proceso para su preparacion,su uso para la manufactura de un medicamento y medicamento que la contiene
NO20005158L (no) FremgangsmÕte for fremstilling av R-(+)-6-karboksamido-3-N- metylamino-1,2,3,4-tetrahydrokarbazol
NO911465L (no) Fremgangsmaate for fremstilling av 4-(3-(4-oksotiazoldinyl))-butynylaminer og deres anvendelse som medikamenter.

Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed