PE96999A1 - 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto - Google Patents
1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuestoInfo
- Publication number
- PE96999A1 PE96999A1 PE1998000626A PE00062698A PE96999A1 PE 96999 A1 PE96999 A1 PE 96999A1 PE 1998000626 A PE1998000626 A PE 1998000626A PE 00062698 A PE00062698 A PE 00062698A PE 96999 A1 PE96999 A1 PE 96999A1
- Authority
- PE
- Peru
- Prior art keywords
- preparation
- termodinamicamente
- metoxifenoxi
- carbazoliloxi
- etilamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA FORMA CRISTALINA (FORMA I) TERMODINAMICAMENTE ESTABLE DE CARVEDILOL LIBRE DE FORMAS DE SIMILARES CARACTERISTICAS FISICAS; CARACTERIZADA POR a)SU PATRON DE DIFRACCION DE RAYOS X, b)SU ESPECTRO INFRARROJO, b)SU PUNTO DE FUSION DE 123�C-126�C. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION Y AISLAMIENTO. EL CARVEDILOL PUEDE SER UTIL PARA LA PROFILAXIS O EL TRATAMIENTO DE ENFERMEDADES CIRCULATORIAS Y CARDIACAS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97112491A EP0893440A1 (en) | 1997-07-22 | 1997-07-22 | Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it |
Publications (1)
Publication Number | Publication Date |
---|---|
PE96999A1 true PE96999A1 (es) | 1999-10-12 |
Family
ID=8227094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1998000626A PE96999A1 (es) | 1997-07-22 | 1998-07-15 | 1-(4-carbazoliloxi)-3-[2-(2-metoxifenoxi)etilamino]-2-propanol termodinamicamente estable, proceso para su preparacion y composiciones farmaceuticas que contienen dicho compuesto |
Country Status (32)
Country | Link |
---|---|
EP (2) | EP0893440A1 (es) |
JP (1) | JP2001510824A (es) |
KR (1) | KR100336229B1 (es) |
CN (1) | CN1125047C (es) |
AR (1) | AR015133A1 (es) |
AT (1) | ATE236123T1 (es) |
AU (1) | AU740453B2 (es) |
BR (1) | BR9810776A (es) |
CA (1) | CA2296637C (es) |
CZ (1) | CZ296947B6 (es) |
DE (1) | DE69812964T2 (es) |
DK (1) | DK1000027T3 (es) |
ES (1) | ES2195366T3 (es) |
HK (1) | HK1029339A1 (es) |
HR (1) | HRP980406A2 (es) |
HU (1) | HUP0003198A3 (es) |
IL (1) | IL133677A (es) |
MA (1) | MA26523A1 (es) |
MY (1) | MY117734A (es) |
NO (1) | NO313588B1 (es) |
NZ (1) | NZ502136A (es) |
PE (1) | PE96999A1 (es) |
PL (1) | PL191602B1 (es) |
PT (1) | PT1000027E (es) |
RU (1) | RU2202542C2 (es) |
SI (1) | SI1000027T1 (es) |
TR (1) | TR200000148T2 (es) |
TW (1) | TW505631B (es) |
UY (1) | UY25108A1 (es) |
WO (1) | WO1999005105A1 (es) |
YU (1) | YU2200A (es) |
ZA (1) | ZA986475B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2227206T3 (es) * | 2000-04-03 | 2005-04-01 | F. Hoffmann-La Roche Ag | Soluciones concentradas de carvedilol. |
MXPA02012795A (es) | 2000-06-28 | 2004-07-30 | Teva Pharma | Carvedilol. |
EP1655285A1 (en) * | 2000-06-28 | 2006-05-10 | Teva Pharmaceutical Industries Ltd. | Method for preparation of a crystalline form of carvedilol (form II) |
ATE328595T1 (de) * | 2001-07-13 | 2006-06-15 | Smithkline Beecham Corp | Carvedilolpolymorph |
EP1929998A3 (en) | 2001-09-21 | 2008-11-26 | Egalet A/S | Controlled release solid dispersions of carvedilol |
ES2291503T3 (es) * | 2001-09-28 | 2008-03-01 | F. Hoffmann-La Roche Ag | Formas pseudopolimorficas de carvedilol. |
MXPA04006909A (es) | 2002-01-15 | 2005-04-19 | Teva Pharma | Solidos cristalinos de carvedilol y procesos para su preparacion. |
WO2003092622A2 (en) * | 2002-04-30 | 2003-11-13 | Sb Pharmco Puerto Rico Inc. | Carvedilol monocitrate monohydrate |
EP1539140A4 (en) * | 2002-06-27 | 2005-12-07 | Sb Pharmco Inc | CARVEDILOLHYDOBROMID |
BR0312102A (pt) * | 2002-06-27 | 2007-05-29 | Sb Pharmco Inc | sais de fosfato de carvedilol e/ou seus solvatos, composições correspondentes, e/ou métodos de tratamento |
EP1562552A1 (en) * | 2002-11-08 | 2005-08-17 | Egalet A/S | Controlled release carvedilol compositions |
EP1610767B1 (en) | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphine controlled release system |
WO2004094378A1 (en) * | 2003-04-21 | 2004-11-04 | Matrix Laboratories Ltd | Process for the preparation of carvedilol form-ii |
SI21616A (sl) * | 2003-09-02 | 2005-04-30 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nove kristalne oblike karvedilola |
JP2007512372A (ja) * | 2003-11-25 | 2007-05-17 | エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド | カルベジロール塩、対応する組成物、送達および/または治療方法 |
PT1838670E (pt) * | 2004-12-09 | 2009-12-18 | Zach System Spa | Processo para a preparação de carvedilol e seus enantiómeros |
US20070043099A1 (en) * | 2005-06-09 | 2007-02-22 | Igor Lifshitz | Crystalline forms of carvedilol and processes for their preparation |
US8022094B2 (en) | 2006-06-28 | 2011-09-20 | Teva Pharmaceutical Industries Ltd. | Carvedilol phosphate |
US20080249317A1 (en) * | 2007-04-04 | 2008-10-09 | Apotex Inc. | Novel amorphous form of carvedilol phosphate and processes for the preparation thereof |
EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
AU2010265213B2 (en) | 2009-06-24 | 2012-08-23 | Egalet Ltd. | Controlled release formulations |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2815926A1 (de) * | 1978-04-13 | 1979-10-18 | Boehringer Mannheim Gmbh | Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3319027A1 (de) * | 1983-05-26 | 1984-11-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten |
-
1997
- 1997-07-22 EP EP97112491A patent/EP0893440A1/en not_active Withdrawn
-
1998
- 1998-07-15 PE PE1998000626A patent/PE96999A1/es not_active Application Discontinuation
- 1998-07-15 MY MYPI98003245A patent/MY117734A/en unknown
- 1998-07-18 CZ CZ20000221A patent/CZ296947B6/cs not_active IP Right Cessation
- 1998-07-18 ES ES98937576T patent/ES2195366T3/es not_active Expired - Lifetime
- 1998-07-18 PT PT98937576T patent/PT1000027E/pt unknown
- 1998-07-18 WO PCT/EP1998/004475 patent/WO1999005105A1/en active IP Right Grant
- 1998-07-18 IL IL13367798A patent/IL133677A/en not_active IP Right Cessation
- 1998-07-18 TR TR2000/00148T patent/TR200000148T2/xx unknown
- 1998-07-18 CN CN98807436A patent/CN1125047C/zh not_active Expired - Fee Related
- 1998-07-18 DK DK98937576T patent/DK1000027T3/da active
- 1998-07-18 RU RU2000103033/04A patent/RU2202542C2/ru not_active IP Right Cessation
- 1998-07-18 PL PL338432A patent/PL191602B1/pl unknown
- 1998-07-18 AU AU86319/98A patent/AU740453B2/en not_active Ceased
- 1998-07-18 HU HU0003198A patent/HUP0003198A3/hu unknown
- 1998-07-18 AT AT98937576T patent/ATE236123T1/de not_active IP Right Cessation
- 1998-07-18 SI SI9830442T patent/SI1000027T1/xx unknown
- 1998-07-18 CA CA002296637A patent/CA2296637C/en not_active Expired - Fee Related
- 1998-07-18 BR BR9810776-3A patent/BR9810776A/pt not_active Application Discontinuation
- 1998-07-18 YU YU2200A patent/YU2200A/sh unknown
- 1998-07-18 NZ NZ502136A patent/NZ502136A/en unknown
- 1998-07-18 JP JP2000504104A patent/JP2001510824A/ja active Pending
- 1998-07-18 DE DE69812964T patent/DE69812964T2/de not_active Expired - Fee Related
- 1998-07-18 TW TW087111738A patent/TW505631B/zh not_active IP Right Cessation
- 1998-07-18 EP EP98937576A patent/EP1000027B1/en not_active Expired - Lifetime
- 1998-07-18 KR KR1020007000667A patent/KR100336229B1/ko not_active IP Right Cessation
- 1998-07-20 MA MA25178A patent/MA26523A1/fr unknown
- 1998-07-21 AR ARP980103547A patent/AR015133A1/es unknown
- 1998-07-21 ZA ZA9806475A patent/ZA986475B/xx unknown
- 1998-07-22 UY UY25108A patent/UY25108A1/es not_active IP Right Cessation
- 1998-07-22 HR HR97112491.2A patent/HRP980406A2/hr not_active Application Discontinuation
-
2000
- 2000-01-21 NO NO20000301A patent/NO313588B1/no unknown
-
2001
- 2001-01-02 HK HK01100012A patent/HK1029339A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |