PE20190380A1 - Composiciones para activacion de nrf2 mejorada y sus metodos de uso - Google Patents

Composiciones para activacion de nrf2 mejorada y sus metodos de uso

Info

Publication number
PE20190380A1
PE20190380A1 PE2018000340A PE2018000340A PE20190380A1 PE 20190380 A1 PE20190380 A1 PE 20190380A1 PE 2018000340 A PE2018000340 A PE 2018000340A PE 2018000340 A PE2018000340 A PE 2018000340A PE 20190380 A1 PE20190380 A1 PE 20190380A1
Authority
PE
Peru
Prior art keywords
extract
luteolin
specified
enhanced
compositions
Prior art date
Application number
PE2018000340A
Other languages
English (en)
Inventor
Brooks Michael Hybertson
Joe Milton Mccord
Original Assignee
Pathways Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pathways Bioscience Llc filed Critical Pathways Bioscience Llc
Publication of PE20190380A1 publication Critical patent/PE20190380A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

SE REFIERE A UNA COMPOSICION QUE COMPRENDE: i) EXTRACTO DE ROMERO QUE ESTA ESPECIFICADO AL 5-10% DE CARNOSOL, ii) EXTRACTO DE JENGIBRE QUE ESTA ESPECIFICADO AL 10-20% DE 6-SHOGAOL, iii) LUTEOLINA QUE ESTA ESPECIFICADO AL 95-99% DE LUTEOLINA, iv) EXTRACTO DE CARDO LECHERO, Y v) EXTRACTO DE BACOPA MONNIERI; DONDE LA RELACION ENTRE LOS CINCO COMPONENTES ES DE 10:5:1:30:48 (P/P). DICHA COMPOSICION COMPRENDE DOS O MAS PRODUCTOS FITOQUIMICOS TALES COMO CARNOSOL, ACIDO CARNOSICO, SHOGAOL, GINGEROL, LUTEOLINA Y WITAFERINA A, EN UNA CANTIDAD EFICAZ PARA ACTIVAR LA VIA DE Nrf2 (FACTOR 2 RELACIONADO CON FACTOR NUCLEAR ERITROIDE 2), SIENDO UTIL PARA PREVENIR Y/O TRATAR CONDICIONES DE SALUD ASOCIADAS CON INFLAMACION O ESTRES OXIDATIVO
PE2018000340A 2015-09-03 2016-09-02 Composiciones para activacion de nrf2 mejorada y sus metodos de uso PE20190380A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562214175P 2015-09-03 2015-09-03
US201662355810P 2016-06-28 2016-06-28

Publications (1)

Publication Number Publication Date
PE20190380A1 true PE20190380A1 (es) 2019-03-08

Family

ID=58188643

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2018000340A PE20190380A1 (es) 2015-09-03 2016-09-02 Composiciones para activacion de nrf2 mejorada y sus metodos de uso

Country Status (9)

Country Link
US (1) US11413269B2 (es)
JP (1) JP6901787B2 (es)
CN (1) CN108136209A (es)
CL (1) CL2018000573A1 (es)
CO (1) CO2018003454A2 (es)
HK (1) HK1256480A1 (es)
MX (2) MX2018002743A (es)
PE (1) PE20190380A1 (es)
WO (1) WO2017041054A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3481409A4 (en) * 2016-07-11 2020-03-18 The State of Isreal, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) TREATMENT OF FOLLICULAR TONSILLITIS WITH PLANT EXTRACTS WITH CARNOSIC ACID
CN110545831A (zh) * 2017-04-27 2019-12-06 帝斯曼知识产权资产管理有限公司 Withania somnifera提取物提供针对空气污染相关疾病的保护的用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888514A (en) * 1997-05-23 1999-03-30 Weisman; Bernard Natural composition for treating bone or joint inflammation
US9265808B2 (en) * 2004-03-23 2016-02-23 Lifeline Nutraceuticals Corporation Compositions for alleviating inflammation and oxidative stress in a mammal
WO2006073042A1 (ja) * 2005-01-05 2006-07-13 Toagosei Co., Ltd. Ｎｒｆ２依存遺伝子の活性化剤
CA2648273A1 (en) * 2006-04-03 2007-10-11 Nestec S.A. Nutritional compositions for promotion of bone growth and maintenance of bone health and methods regarding same
EP2265126A4 (en) 2008-03-10 2011-06-29 Univ Louisville Res Found METHODS AND COMPOSITIONS FOR CONTROLLED DELIVERY OF PHYTOHEMICAL AGENTS
JP5608646B2 (ja) 2008-07-31 2014-10-15 シャクリー コーポレーション 向上した抗酸化活性を有するマスカダイン組成物
JP2011057654A (ja) 2009-09-14 2011-03-24 Iwate Univ メタボリックシンドローム治療又は予防薬、及び脂肪細胞分化抑制方法
WO2011075843A1 (en) 2009-12-24 2011-06-30 The Royal Institution For The Avancement Of Learning/Mcgill University Compositions and methods for preventing and treating diseases and environmentally induced health disorders
KR101254847B1 (ko) * 2010-05-27 2013-04-15 한림대학교 산학협력단 실리비닌(silibinin)을 포함하는 골다공증 치료 및 예방용 조성물
WO2012142511A2 (en) 2011-04-15 2012-10-18 Md Matrix Health Llc Dba Md Matrix Health Inc Orthomolecular compositions and their use in stabilizing the extracellular matrix
WO2013108056A1 (es) * 2012-01-16 2013-07-25 Velez-Rivera Hector De Jesus Fitocomposición para el tratamiento de dolores relacionados con enfermedades articulares
JP2013209351A (ja) * 2012-03-30 2013-10-10 Sunstar Inc 抗酸化機能亢進剤
US20140287071A1 (en) * 2013-01-17 2014-09-25 Lifevantage Corporation Veterinary supplements
WO2014151891A1 (en) 2013-03-14 2014-09-25 Walley Darlene Topical products
US10596115B2 (en) * 2013-07-17 2020-03-24 Council Of Scientific & Industrial Research Pharmaceutical composition for the treatment of diminution of bone tissue
WO2016037971A1 (en) 2014-09-08 2016-03-17 Bios Line S.P.A. Compositions comprising glucosinolates precursors of sulforaphane in combination with extracts of rosemary

Also Published As

Publication number Publication date
WO2017041054A1 (en) 2017-03-09
US20180250264A1 (en) 2018-09-06
CL2018000573A1 (es) 2019-01-11
CN108136209A (zh) 2018-06-08
HK1256480A1 (zh) 2019-09-27
CO2018003454A2 (es) 2018-08-31
MX2022009446A (es) 2022-09-05
MX2018002743A (es) 2018-06-06
US11413269B2 (en) 2022-08-16
JP2018529763A (ja) 2018-10-11
JP6901787B2 (ja) 2021-07-14

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