PE20171082A1 - PROCESS TO INCREASE THE STABILITY OF A COMPOSITION INCLUDING POLYINSATURATED OMEGA-6 FATTY ACIDS - Google Patents
PROCESS TO INCREASE THE STABILITY OF A COMPOSITION INCLUDING POLYINSATURATED OMEGA-6 FATTY ACIDSInfo
- Publication number
- PE20171082A1 PE20171082A1 PE2017001086A PE2017001086A PE20171082A1 PE 20171082 A1 PE20171082 A1 PE 20171082A1 PE 2017001086 A PE2017001086 A PE 2017001086A PE 2017001086 A PE2017001086 A PE 2017001086A PE 20171082 A1 PE20171082 A1 PE 20171082A1
- Authority
- PE
- Peru
- Prior art keywords
- composition
- weight
- omega
- fatty acids
- lysine
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 9
- 229940033080 omega-6 fatty acid Drugs 0.000 title abstract 4
- 235000020665 omega-6 fatty acid Nutrition 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 2
- 239000004472 Lysine Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012265 solid product Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B5/00—Preserving by using additives, e.g. anti-oxidants
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B5/00—Preserving by using additives, e.g. anti-oxidants
- C11B5/0021—Preserving by using additives, e.g. anti-oxidants containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B5/00—Preserving by using additives, e.g. anti-oxidants
- C11B5/0085—Substances of natural origin of unknown constitution, f.i. plant extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/18—Lipids
- A23V2250/186—Fatty acids
- A23V2250/1882—Polyunsaturated fatty acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Botany (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se refiere a un proceso para aumentar la estabilidad hacia la oxidacion de una composicion que comprende acidos grasos omega-6 poliinsaturados que comprende las siguientes etapas: (i) proporcionar una composicion de partida que comprende al menos un componente acido graso omega-6 poliinsaturado; (ii) proporcionar una composicion de lisina; (iii) mezclar soluciones acuosas, acuoso-alcoholicas o alcoholicas de composicion de partida y composicion de lisina, y someter posteriormente la mezcla resultante a condiciones de secado por pulverizacion, formando asi una composicion de producto solido que comprende al menos una sal de un cation derivado de lisina con un anion derivado a partir de un acido graso omega-6 poliinsaturado; la composicion del producto que presenta un contenido de disolvente SC seleccionado entre los siguientes: SC <5% en peso, SC <3% en peso, SC <1 %en peso, SC <0.5% en peso. Dichos compuestos obtenibles son utiles en el tratamiento de cancerIt refers to a process for increasing the oxidation stability of a composition comprising polyunsaturated omega-6 fatty acids comprising the following steps: (i) providing a starting composition comprising at least one polyunsaturated omega-6 fatty acid component; (ii) providing a lysine composition; (iii) mixing aqueous, aqueous-alcoholic or alcoholic solutions of the starting composition and lysine composition, and subsequently subjecting the resulting mixture to spray-drying conditions, thus forming a solid product composition comprising at least one salt of a cation derivative of lysine with an anion derived from a polyunsaturated omega-6 fatty acid; the composition of the product having a solvent content SC selected from the following: SC <5% by weight, SC <3% by weight, SC <1% by weight, SC <0.5% by weight. Said obtainable compounds are useful in the treatment of cancer
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14199976 | 2014-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20171082A1 true PE20171082A1 (en) | 2017-08-03 |
Family
ID=52344990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2017001086A PE20171082A1 (en) | 2014-12-23 | 2015-12-17 | PROCESS TO INCREASE THE STABILITY OF A COMPOSITION INCLUDING POLYINSATURATED OMEGA-6 FATTY ACIDS |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20170367394A1 (en) |
| EP (1) | EP3236783B1 (en) |
| JP (1) | JP6714000B2 (en) |
| KR (1) | KR20170094789A (en) |
| CN (1) | CN107105693B (en) |
| AU (1) | AU2015371457B2 (en) |
| BR (1) | BR112017013445B1 (en) |
| CA (1) | CA2969157C (en) |
| CL (1) | CL2017001613A1 (en) |
| CO (1) | CO2017005849A2 (en) |
| DK (1) | DK3236783T3 (en) |
| ES (1) | ES2776393T3 (en) |
| IL (1) | IL252482B (en) |
| MX (1) | MX2017008274A (en) |
| MY (1) | MY190506A (en) |
| NZ (1) | NZ732380A (en) |
| PE (1) | PE20171082A1 (en) |
| PH (1) | PH12017501144A1 (en) |
| PL (1) | PL3236783T3 (en) |
| RU (1) | RU2706072C2 (en) |
| SA (1) | SA517381762B1 (en) |
| SG (1) | SG11201704399RA (en) |
| TW (1) | TWI693893B (en) |
| WO (1) | WO2016102316A1 (en) |
| ZA (1) | ZA201704821B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3072658C (en) | 2017-08-15 | 2023-01-24 | Evonik Operations Gmbh | Tablets with high active ingredient content of omega-3 fatty acid amino acid salts |
| WO2019093708A1 (en) * | 2017-11-08 | 2019-05-16 | 김승수 | Method for producing odor-suppressing composition containing unsaturated oil and arginine |
| WO2021023857A1 (en) | 2019-08-08 | 2021-02-11 | Evonik Operations Gmbh | Solubility enhancement of poorly soluble actives |
| TW202120076A (en) * | 2019-08-08 | 2021-06-01 | 德商贏創運營有限公司 | Down streaming process for the production of polyunsaturated fatty acid salts |
| EP4009960A1 (en) | 2019-08-08 | 2022-06-15 | Evonik Operations GmbH | Method of preparing a solid dosage form and a binder |
| EP4009959A1 (en) | 2019-08-08 | 2022-06-15 | Evonik Operations GmbH | Method of preparing a solid dosage form and a lubricant |
| EP3804699A1 (en) | 2019-10-10 | 2021-04-14 | Evonik Operations GmbH | Method of preparing a solid dosage form and a binder |
| JP2023514505A (en) * | 2020-01-30 | 2023-04-06 | シリサイクル インコーポレイティド | Method for preparing basic amino acid solid salt of polyunsaturated fatty acid |
| US20230037453A1 (en) | 2020-04-01 | 2023-02-09 | Evonik Operations Gmbh | Preparation for use as vasorelaxant |
| EP4125438A1 (en) | 2020-04-01 | 2023-02-08 | Evonik Operations GmbH | Preparation for use as antioxidant |
| CN111635306B (en) * | 2020-06-12 | 2022-09-27 | 上海海益环保科技有限公司 | Erucic acid composite stabilizer and method for preparing stable erucic acid |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1264987B1 (en) * | 1993-12-14 | 1996-10-17 | Prospa Bv | SALTS OF A POLYUNSATURATED FATTY ACID AND PHARMACEUTICAL FORMULATIONS THAT CONTAIN THEM |
| AU2003284633B2 (en) * | 2002-11-22 | 2008-07-10 | Nippon Suisan Kaisha, Ltd. | External composition containing polyunsaturated fatty acid or its salt or ester |
| WO2004112777A1 (en) * | 2003-06-20 | 2004-12-29 | Mochida Pharmaceutical Co., Ltd. | Composition for prevention/treatment for varicose vein |
| CN101115404B (en) * | 2005-02-02 | 2013-06-05 | 帝斯曼知识产权资产管理有限公司 | Powder compositions |
| US20140199313A1 (en) * | 2005-03-02 | 2014-07-17 | Metanomics Gmbh | Process for the Production of Fine Chemicals |
| NZ573327A (en) * | 2006-06-05 | 2012-07-27 | Ocean Nutrition Canada Ltd | Microcapsules with improved shells |
| WO2008003064A2 (en) * | 2006-06-29 | 2008-01-03 | Martek Biosciences Corporation | Sweetened oil compositions and methods of making |
| CN101909467B (en) * | 2007-11-01 | 2013-04-24 | 恩兹默泰克有限公司 | Lipid mixture for infant nutrition |
| WO2012002464A1 (en) * | 2010-06-30 | 2012-01-05 | 持田製薬株式会社 | ω3 FATTY ACID COMPOUND PREPARATION |
-
2015
- 2015-12-17 SG SG11201704399RA patent/SG11201704399RA/en unknown
- 2015-12-17 MX MX2017008274A patent/MX2017008274A/en unknown
- 2015-12-17 PE PE2017001086A patent/PE20171082A1/en unknown
- 2015-12-17 CN CN201580070558.XA patent/CN107105693B/en active Active
- 2015-12-17 PL PL15820481T patent/PL3236783T3/en unknown
- 2015-12-17 JP JP2017533761A patent/JP6714000B2/en active Active
- 2015-12-17 CA CA2969157A patent/CA2969157C/en active Active
- 2015-12-17 RU RU2017125963A patent/RU2706072C2/en active
- 2015-12-17 AU AU2015371457A patent/AU2015371457B2/en active Active
- 2015-12-17 WO PCT/EP2015/080293 patent/WO2016102316A1/en active Application Filing
- 2015-12-17 KR KR1020177016895A patent/KR20170094789A/en not_active Application Discontinuation
- 2015-12-17 MY MYPI2017702257A patent/MY190506A/en unknown
- 2015-12-17 US US15/538,719 patent/US20170367394A1/en not_active Abandoned
- 2015-12-17 EP EP15820481.8A patent/EP3236783B1/en active Active
- 2015-12-17 BR BR112017013445-4A patent/BR112017013445B1/en active IP Right Grant
- 2015-12-17 ES ES15820481T patent/ES2776393T3/en active Active
- 2015-12-17 NZ NZ732380A patent/NZ732380A/en unknown
- 2015-12-17 DK DK15820481.8T patent/DK3236783T3/en active
- 2015-12-18 TW TW104142797A patent/TWI693893B/en active
-
2017
- 2017-05-24 IL IL252482A patent/IL252482B/en unknown
- 2017-06-14 CO CONC2017/0005849A patent/CO2017005849A2/en unknown
- 2017-06-18 SA SA517381762A patent/SA517381762B1/en unknown
- 2017-06-19 CL CL2017001613A patent/CL2017001613A1/en unknown
- 2017-06-19 PH PH12017501144A patent/PH12017501144A1/en unknown
- 2017-07-17 ZA ZA2017/04821A patent/ZA201704821B/en unknown
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