PE20110330A1 - Composicion topica para el tratamiento de queratosis actinica - Google Patents
Composicion topica para el tratamiento de queratosis actinicaInfo
- Publication number
- PE20110330A1 PE20110330A1 PE2010001215A PE2010001215A PE20110330A1 PE 20110330 A1 PE20110330 A1 PE 20110330A1 PE 2010001215 A PE2010001215 A PE 2010001215A PE 2010001215 A PE2010001215 A PE 2010001215A PE 20110330 A1 PE20110330 A1 PE 20110330A1
- Authority
- PE
- Peru
- Prior art keywords
- weight
- treatment
- group
- actinic keratosis
- same
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 208000009621 actinic keratosis Diseases 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title 1
- 150000001298 alcohols Chemical class 0.000 abstract 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 2
- -1 CARBOXYL ACIDS Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 229920002678 cellulose Chemical class 0.000 abstract 1
- 239000001913 cellulose Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229920001519 homopolymer Polymers 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
- 239000002599 prostaglandin synthase inhibitor Substances 0.000 abstract 1
- 102000027483 retinoid hormone receptors Human genes 0.000 abstract 1
- 108091008679 retinoid hormone receptors Proteins 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
- ORGHESHFQPYLAO-UHFFFAOYSA-N vinyl radical Chemical class C=[CH] ORGHESHFQPYLAO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION DE GEL TOPICA QUE COMPRENDE A) UN AGENTE ACTIVO PARA EL TRATAMIENTO DE LA QUERATOSIS ACTINICA QUE COMPRENDE 0,25 Y 4,5% EN PESO SELECCIONADO DEL GRUPO DE INHIBIDORES DE CICLOOXIGENASA, MODULADORES INMUNOLOGICOS TOPICOS, ANTIMETABOLITOS Y MEZCLAS DE LO MISMOS; B) UN AGENTE QUERATOLITICAMENTE ACTIVO QUE COMPRENDE ENTRE 0,025 Y 30% EN PESO SELECCIONADO ENTRE AGONISTAS DEL RECEPTOR RETINOIDE, UREA, ACIDOS ORGANICOS TALES COMO ACIDO GLICOLICO, ACIDO SALICILICO, ACIDO LACTICO, ENTRE OTROS, Y MEZCLAS DE LOS MISMOS; C) UN FORMADOR DE GEL QUE COMPRENDE ENTRE 1 Y 30% EN PESO SELECCIONADO DE HOMOPOLIMEROS Y COPOLIMEROS DE VINILO, DERIVADOS DE CELULOSA Y MEZCLAS DE LOS MISMOS; D) UN SOVENTE ORGANICO QUE COMPRENDE ENTRE 1 Y 90% EN PESO SELECCIONADO DEL GRUPO DE ALCOHOLES C1-C10, ESTERES DE ALCOHOLES C1-C10 CON ACIDOS CARBOXILICOS C1-C10 Y MEZCLAS DE LOS MISMOS. ADEMAS PUEDE CONTENER UN MEJORADOR DE PENETRACION DE LA PIEL SELECCIONADO DEL GRUPO DE ALCOHOLES POLIVALENTES ALIFATICOS C2-C10, POLIALQUILENGLICOLES, ETERES NO ALCOXILADOS, ENTRE OTROS. DICHA COMPOSICION COMPRENDE MENOS QUE UN 5% EN PESO DE AGUA, TIENE UNA VISCOSIDAD ENTRE 300 A 1500 mPas A 20ºC, UTIL EN EL TRATAMIENTO DE QUERATOSIS ACTINICA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08012237A EP2143421A1 (en) | 2008-07-07 | 2008-07-07 | Topical composition for the treatment of actinic keratosis |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20110330A1 true PE20110330A1 (es) | 2011-06-11 |
Family
ID=40039993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2010001215A PE20110330A1 (es) | 2008-07-07 | 2009-06-29 | Composicion topica para el tratamiento de queratosis actinica |
Country Status (32)
Country | Link |
---|---|
US (1) | US8569320B2 (es) |
EP (2) | EP2143421A1 (es) |
JP (2) | JP5654987B2 (es) |
KR (1) | KR101689898B1 (es) |
CN (2) | CN102088957A (es) |
AR (1) | AR072685A1 (es) |
AU (1) | AU2009267471B2 (es) |
BR (1) | BRPI0915439B8 (es) |
CA (1) | CA2729974A1 (es) |
CL (1) | CL2010001642A1 (es) |
CO (1) | CO6351710A2 (es) |
CY (1) | CY1116111T1 (es) |
DK (1) | DK2315581T3 (es) |
EA (1) | EA019533B1 (es) |
EC (1) | ECSP11010762A (es) |
ES (1) | ES2532948T3 (es) |
HK (1) | HK1154793A1 (es) |
HR (1) | HRP20150222T1 (es) |
IL (1) | IL210134A (es) |
ME (1) | ME02147B (es) |
MX (1) | MX2011000054A (es) |
MY (1) | MY158428A (es) |
NZ (1) | NZ590288A (es) |
PE (1) | PE20110330A1 (es) |
PL (1) | PL2315581T3 (es) |
PT (1) | PT2315581E (es) |
RS (1) | RS53887B1 (es) |
SI (1) | SI2315581T1 (es) |
TW (1) | TWI433692B (es) |
UA (1) | UA101044C2 (es) |
WO (1) | WO2010003568A1 (es) |
ZA (1) | ZA201100653B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2775089C (en) * | 2009-10-08 | 2015-12-08 | Msd Consumer Care, Inc. | Low ether composition and delivery apparatus |
JP5950528B2 (ja) * | 2011-09-30 | 2016-07-13 | 小林製薬株式会社 | 皮膜形成性外用製剤 |
WO2013088380A1 (en) * | 2011-12-12 | 2013-06-20 | Leo Laboratories Limited | Gel compositions |
NZ606177A (en) * | 2012-01-30 | 2014-03-28 | Dolorgiet Gmbh & Co Kg | Compositions for the treatment of actinic keratosis |
GB201222405D0 (en) * | 2012-12-12 | 2013-01-23 | Leo Lab Ltd | Gel compositions |
RU2017106013A (ru) | 2014-07-31 | 2018-08-28 | Сан Фармасьютикал Индастриз Лимитед | Фармацевтическая композиция изотретиноина для перорального приема |
EP3338783B1 (en) | 2014-09-12 | 2024-01-24 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
GB201509326D0 (en) | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
RU2706234C2 (ru) | 2015-07-10 | 2019-11-15 | Инфектофарм Арцнаймиттель Унд Консилиум Гмбх | Применение гидроксида калия при лечении актинического кератоза |
GB201604484D0 (en) | 2016-03-16 | 2016-04-27 | Antibiotx Aps And Københavns Uni University Of Copenhagen | Topical antibacterial compositions |
WO2018165647A1 (en) | 2017-03-10 | 2018-09-13 | Athenex, Inc. | Methods of treating and/or preventing actinic keratosis |
US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
US20220175769A1 (en) * | 2020-12-08 | 2022-06-09 | Ankh Life Sciences Limited | Method of treatment of actinic keratoses |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2802005A (en) | 1957-08-06 | S-eluorourace | ||
US4234599A (en) * | 1978-10-04 | 1980-11-18 | Scott Eugene J Van | Treatment of skin keratoses with α-hydroxy acids and related compounds |
US5091171B2 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use |
US5167649A (en) * | 1988-08-22 | 1992-12-01 | Zook Gerald P | Drug delivery system for the removal of dermal lesions |
US5093360A (en) * | 1989-04-07 | 1992-03-03 | Yu Ruey J | Retinal, derivatives and their therapeutic use |
GB9023701D0 (en) * | 1990-10-31 | 1990-12-12 | Efamol Holdings | Medical treatment |
JP3117502B2 (ja) * | 1991-08-27 | 2000-12-18 | 株式会社資生堂 | 皮膚外用剤 |
US5627187A (en) | 1995-04-12 | 1997-05-06 | Katz; Bruce E. | 5-FU for treating actinic kerotoses |
KR20030097619A (ko) * | 1996-06-20 | 2003-12-31 | 라비팜 에스.아. | 여드름의 국소 치료 제형 |
US5993787A (en) * | 1996-09-13 | 1999-11-30 | Johnson & Johnson Consumer Products, Inc. | Composition base for topical therapeutic and cosmetic preparations |
US5955097A (en) * | 1996-10-18 | 1999-09-21 | Virotex Corporation | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
US6462071B1 (en) * | 2000-03-02 | 2002-10-08 | Vitreo-Retinal Technologies, Inc. | Agents for intravitreal administration to treat or prevent disorders of the eye |
ES2223277B1 (es) * | 2003-06-19 | 2006-03-01 | Fernando Bouffard Fita | Composicion anestesica para administracion topica. |
CA2776692C (en) * | 2003-08-25 | 2014-12-30 | Foamix Ltd. | Penetrating pharmaceutical foam |
WO2005027977A2 (en) * | 2003-09-22 | 2005-03-31 | Agis Industries (1983) Ltd. | Diclofenac compositions for the treatment of skin disorders |
WO2006012146A2 (en) * | 2004-06-24 | 2006-02-02 | Idexx Laboratories, Inc. | Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same |
US20070053984A1 (en) | 2005-03-03 | 2007-03-08 | Monique Spann-Wade | Topical gels compositions |
WO2006134406A1 (en) * | 2005-06-14 | 2006-12-21 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable pharmaceutical gel of diclofenac sodium |
US7851431B2 (en) * | 2005-07-27 | 2010-12-14 | Prescription Dispensing Laboratories | Treatment of actinic keratoses with calcium channel blockers |
US20070264317A1 (en) * | 2006-05-15 | 2007-11-15 | Perrigo Israel Pharmaceuticals Ltd. | Imiquimod cream formulation |
WO2008047857A1 (fr) * | 2006-10-18 | 2008-04-24 | Fujifilm Corporation | Procédé de production d'une composition comprenant un composé difficilement soluble dans l'eau incorporé dans une matrice hydrophile et préparation pour une utilisation externe comprenant un agent ou médicament anticancéreux ayant un coefficient de partage octanol/eau (log p) de -3,0 ou plus mais pas plus de 3,0, incorporé |
-
2008
- 2008-07-07 EP EP08012237A patent/EP2143421A1/en not_active Withdrawn
-
2009
- 2009-06-29 SI SI200931142T patent/SI2315581T1/sl unknown
- 2009-06-29 UA UAA201101405A patent/UA101044C2/ru unknown
- 2009-06-29 WO PCT/EP2009/004682 patent/WO2010003568A1/en active Application Filing
- 2009-06-29 PE PE2010001215A patent/PE20110330A1/es not_active Application Discontinuation
- 2009-06-29 MX MX2011000054A patent/MX2011000054A/es active IP Right Grant
- 2009-06-29 AU AU2009267471A patent/AU2009267471B2/en active Active
- 2009-06-29 JP JP2011516999A patent/JP5654987B2/ja active Active
- 2009-06-29 ES ES09776876.6T patent/ES2532948T3/es active Active
- 2009-06-29 ME MEP-2015-38A patent/ME02147B/me unknown
- 2009-06-29 PL PL09776876T patent/PL2315581T3/pl unknown
- 2009-06-29 MY MYPI2011000028A patent/MY158428A/en unknown
- 2009-06-29 KR KR1020117002825A patent/KR101689898B1/ko active IP Right Grant
- 2009-06-29 CN CN2009801266635A patent/CN102088957A/zh active Pending
- 2009-06-29 PT PT97768766T patent/PT2315581E/pt unknown
- 2009-06-29 CA CA2729974A patent/CA2729974A1/en not_active Abandoned
- 2009-06-29 EA EA201100020A patent/EA019533B1/ru unknown
- 2009-06-29 NZ NZ590288A patent/NZ590288A/xx unknown
- 2009-06-29 RS RS20150185A patent/RS53887B1/en unknown
- 2009-06-29 US US13/002,971 patent/US8569320B2/en active Active
- 2009-06-29 DK DK09776876T patent/DK2315581T3/en active
- 2009-06-29 BR BRPI0915439A patent/BRPI0915439B8/pt active IP Right Grant
- 2009-06-29 CN CN201510185320.3A patent/CN104825384A/zh active Pending
- 2009-06-29 EP EP09776876.6A patent/EP2315581B1/en active Active
- 2009-07-03 AR ARP090102493A patent/AR072685A1/es unknown
- 2009-07-06 TW TW098122756A patent/TWI433692B/zh active
-
2010
- 2010-12-20 IL IL210134A patent/IL210134A/en active IP Right Grant
- 2010-12-30 CL CL2010001642A patent/CL2010001642A1/es unknown
-
2011
- 2011-01-17 EC ECSP11010762 patent/ECSP11010762A/es unknown
- 2011-01-26 ZA ZA2011/00653A patent/ZA201100653B/en unknown
- 2011-02-07 CO CO11013458A patent/CO6351710A2/es not_active Application Discontinuation
- 2011-08-29 HK HK11109094.3A patent/HK1154793A1/xx unknown
-
2014
- 2014-10-16 JP JP2014211989A patent/JP2015038129A/ja not_active Withdrawn
-
2015
- 2015-02-26 HR HRP20150222TT patent/HRP20150222T1/hr unknown
- 2015-03-13 CY CY20151100254T patent/CY1116111T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |