PE20030492A1 - LOW PEROXIDE CONCENTRATION FOR THE TREATMENT OR PREVENTION OF VAGINAL DISEASES - Google Patents
LOW PEROXIDE CONCENTRATION FOR THE TREATMENT OR PREVENTION OF VAGINAL DISEASESInfo
- Publication number
- PE20030492A1 PE20030492A1 PE2002001057A PE2002001057A PE20030492A1 PE 20030492 A1 PE20030492 A1 PE 20030492A1 PE 2002001057 A PE2002001057 A PE 2002001057A PE 2002001057 A PE2002001057 A PE 2002001057A PE 20030492 A1 PE20030492 A1 PE 20030492A1
- Authority
- PE
- Peru
- Prior art keywords
- treatment
- concentration
- prevention
- peroxide concentration
- peroxide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA DE LIBERACION PROLONGADA QUE COMPRENDE UNA MEZCLA SINERGICA DE UNA FUENTE DE PEROXIDO EN UNA CANTIDAD DE 0,01mg A 500mg SELECCIONADO DE PEROXIDO DE CARBAMIDA Y UN BIOADHESIVO TAL COMO UN POLIMERO POLICARBOXILICO, QUE SE HINCHA EN EL AGUA Y QUE ES SOLUBLE EN LA MISMA SELECCIONADO DE POLICARBOFILO, CARACTERIZADA PORQUE SE MANTIENE UNA MUY BAJA CONCENTRACION DE PEROXIDO QUE SE LIBERA DURANTE UN PERIODO PROLONGADO DE AL MENOS 12 HORAS, EN UNA CANTIDAD SUFICIENTE PARA AUMENTAR LA CONCENTRACION DEL OXIGENO EN LA VAGINA, PROPORCIONANDO BENEFICIOS AL DISMINUIR EL pH DE LA VAGINA SIN ESTERILIZACION O SIN ELIMINACION DE LA FLORA VAGINAL LOCAL NORMALMENTE DESEADA. LA COMPOSICION PUEDE SER UTIL PARA EL TRATAMIENTO DE INFECCIONES VAGINALESIT REFERS TO A LONG-RELEASE PHARMACEUTICAL COMPOSITION THAT INCLUDES A SYNERGIC MIXTURE OF A PEROXIDE SOURCE IN A SELECTED QUANTITY OF 0.01mg TO 500mg OF CARBAMIDE PEROXIDE AND A BIOADHESIVE SUCH AS A POLYMER POLYCARBOXYL IT IS SOLUBLE IN THE SAME SELECTED POLYCARBOPHYL, CHARACTERIZED BECAUSE IT MAINTAINS A VERY LOW PEROXIDE CONCENTRATION WHICH IS RELEASED DURING A LONG PERIOD OF AT LEAST 12 HOURS, IN A SUFFICIENT AMOUNT TO INCREASE THE CONCENTRATION OF THE BENEFICIAL OXYGENOUS DISSPORTION IN THE OXYGEN CONCENTRATION THE pH OF THE VAGINA WITHOUT STERILIZATION OR WITHOUT REMOVAL OF THE NORMALLY DESIRED LOCAL VAGINAL FLORA. THE COMPOSITION MAY BE USEFUL FOR THE TREATMENT OF VAGINAL INFECTIONS
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33068301P | 2001-10-29 | 2001-10-29 | |
US10/278,910 US7709026B2 (en) | 2001-10-29 | 2002-10-24 | Low concentration of peroxide for treating or preventing vaginal infections |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20030492A1 true PE20030492A1 (en) | 2003-06-16 |
Family
ID=26959335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2002001057A PE20030492A1 (en) | 2001-10-29 | 2002-10-28 | LOW PEROXIDE CONCENTRATION FOR THE TREATMENT OR PREVENTION OF VAGINAL DISEASES |
Country Status (31)
Country | Link |
---|---|
US (1) | US7709026B2 (en) |
EP (1) | EP1441769B1 (en) |
JP (2) | JP5153049B2 (en) |
KR (1) | KR101009146B1 (en) |
CN (1) | CN1578676A (en) |
AR (1) | AR037047A1 (en) |
AT (1) | ATE297222T1 (en) |
AU (1) | AU2002346897B2 (en) |
BR (1) | BR0213584A (en) |
CA (1) | CA2465133C (en) |
DE (1) | DE60204584T2 (en) |
DK (1) | DK1441769T3 (en) |
ES (1) | ES2243772T3 (en) |
HK (1) | HK1063290A1 (en) |
HR (1) | HRP20040480B1 (en) |
HU (1) | HU229487B1 (en) |
IL (2) | IL161512A0 (en) |
MA (1) | MA26289A1 (en) |
ME (1) | MEP34608A (en) |
MX (1) | MXPA04003977A (en) |
MY (1) | MY137791A (en) |
NO (1) | NO20042199L (en) |
NZ (1) | NZ532294A (en) |
PE (1) | PE20030492A1 (en) |
PL (2) | PL402550A1 (en) |
PT (1) | PT1441769E (en) |
RS (1) | RS51154B (en) |
RU (1) | RU2329829C2 (en) |
SI (1) | SI1441769T1 (en) |
WO (1) | WO2003037382A1 (en) |
ZA (1) | ZA200402943B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
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US8425892B2 (en) * | 2001-10-29 | 2013-04-23 | Columbia Laboratories, Inc. | Extended, controlled-release pharmaceutical compositions using charged polymers |
CH697081A5 (en) * | 2002-01-22 | 2008-04-30 | Andreas F Dr Schaub | Composition for supporting the birth of a human fetuses. |
US20040126369A1 (en) * | 2002-12-30 | 2004-07-01 | Richard Payne | Delivery of peroxide-generating enzymes to the vaginal tract |
DE10328942A1 (en) * | 2003-06-27 | 2005-01-27 | Lts Lohmann Therapie-Systeme Ag | Transmucosal dosage forms with reduced mucous membrane irritation |
ES2237298B1 (en) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | SEMISOLID MUCOADHESIVE FORMULATIONS. |
US20050276865A1 (en) * | 2004-05-20 | 2005-12-15 | Servet Buyuktimkin | Peroxide compounds for the prevention and treatment of sexual dysfunction in humans |
DE102004054552A1 (en) * | 2004-11-11 | 2006-05-18 | Hcb Happy Child Birth Holding Ag | New composition to facilitate human birth |
ES2344673B1 (en) | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | USE OF ESTRIOL IN THE PREPARATION OF A PHARMACEUTICAL FORMULATION FOR THE TREATMENT OF VAGINAL ATROPHY IN WOMEN WITH RISK OF POTOLOGIATUMORAL. |
US10383894B2 (en) * | 2010-03-17 | 2019-08-20 | Lutran Industries, Inc. | Human medicinal treatment using salt of peroxymonosulfuric acid |
US20120074014A1 (en) * | 2010-09-27 | 2012-03-29 | Lutran Industries, Inc. | Product typically based on salt of peroxymonosulfuric acid and suitable for medicinal usage, and associated product fabrication |
GB201108879D0 (en) * | 2011-05-25 | 2011-07-06 | Isis Innovation | Vector |
US9895311B2 (en) | 2014-09-25 | 2018-02-20 | Pharmiva Ab | Foam-forming compositions and methods for delivering an active to a body cavity |
CN110913849A (en) * | 2017-03-30 | 2020-03-24 | 科学派有限责任公司 | Methods of treating and preventing infections |
JP7364556B2 (en) | 2017-05-23 | 2023-10-18 | ファーミバ アーベー | Foam-forming compositions for delivering active substances to body cavities |
EP3870150A1 (en) * | 2018-10-26 | 2021-09-01 | Viramal Limited | Mucoadhesive gel composition |
US11850303B2 (en) | 2020-10-27 | 2023-12-26 | Uqora, Inc. | Gel and a suppository and methods to provide the gel and suppository |
Family Cites Families (48)
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US2798053A (en) | 1952-09-03 | 1957-07-02 | Goodrich Co B F | Carboxylic polymers |
BE535125A (en) | 1954-01-25 | |||
NL108604C (en) | 1957-08-27 | |||
US4127515A (en) * | 1974-10-21 | 1978-11-28 | Colgate-Palmolive Company | Waxing sponge |
US4607101A (en) * | 1981-08-27 | 1986-08-19 | Jaye-Boern Laboratories, Inc. | Method of treating acne vulgaris with a composition containing carbamide peroxide |
JPH0830004B2 (en) * | 1983-11-14 | 1996-03-27 | コロンビア ラボラトリーズ インコーポレイテッド | Bioadhesive composition and method of treatment therewith |
US4657935A (en) * | 1985-07-22 | 1987-04-14 | Carlos Teplicki | Real acne control (RAC) |
US4923677A (en) | 1985-08-07 | 1990-05-08 | Roy T. Witkin | Chemical sterilization |
US4997625A (en) | 1985-08-07 | 1991-03-05 | Simon Gilbert I | Chemical sterilization |
US4670256A (en) | 1985-09-23 | 1987-06-02 | V. Valhalla Corp. | Vaginal conditioning for sexual activity |
US4781923A (en) * | 1987-07-20 | 1988-11-01 | Pellico Michael A | Antiseptic gels |
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US6117859A (en) * | 1997-11-04 | 2000-09-12 | The Research Foundation Of State University Of New York | Method of relieving chronic inflammation by using 5-alkylsulfonylsalicylanilides |
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US6200551B1 (en) | 2000-01-27 | 2001-03-13 | Susan Ann Morgan | Treatment for dry mouth employing carbamide peroxide |
US6235314B1 (en) * | 2000-08-08 | 2001-05-22 | Sarfaraz K. Niazi | Analgesic, anti-inflammatory and skeletal muscle relaxant compositions |
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-
2002
- 2002-10-24 US US10/278,910 patent/US7709026B2/en not_active Expired - Lifetime
- 2002-10-28 WO PCT/EP2002/012043 patent/WO2003037382A1/en active IP Right Grant
- 2002-10-28 EP EP02783026A patent/EP1441769B1/en not_active Expired - Lifetime
- 2002-10-28 RU RU2004116312/15A patent/RU2329829C2/en not_active IP Right Cessation
- 2002-10-28 PL PL402550A patent/PL402550A1/en not_active Application Discontinuation
- 2002-10-28 AT AT02783026T patent/ATE297222T1/en active
- 2002-10-28 NZ NZ532294A patent/NZ532294A/en not_active IP Right Cessation
- 2002-10-28 MX MXPA04003977A patent/MXPA04003977A/en active IP Right Grant
- 2002-10-28 MY MYPI20024019A patent/MY137791A/en unknown
- 2002-10-28 PL PL369725A patent/PL216746B1/en not_active IP Right Cessation
- 2002-10-28 BR BR0213584-1A patent/BR0213584A/en not_active Application Discontinuation
- 2002-10-28 CA CA2465133A patent/CA2465133C/en not_active Expired - Lifetime
- 2002-10-28 CN CNA028215664A patent/CN1578676A/en active Pending
- 2002-10-28 DK DK02783026T patent/DK1441769T3/en active
- 2002-10-28 PT PT02783026T patent/PT1441769E/en unknown
- 2002-10-28 HU HU0401672A patent/HU229487B1/en unknown
- 2002-10-28 RS YUP-366/04A patent/RS51154B/en unknown
- 2002-10-28 PE PE2002001057A patent/PE20030492A1/en not_active Application Discontinuation
- 2002-10-28 JP JP2003539722A patent/JP5153049B2/en not_active Expired - Fee Related
- 2002-10-28 KR KR1020047006272A patent/KR101009146B1/en not_active IP Right Cessation
- 2002-10-28 AU AU2002346897A patent/AU2002346897B2/en not_active Ceased
- 2002-10-28 IL IL16151202A patent/IL161512A0/en unknown
- 2002-10-28 ES ES02783026T patent/ES2243772T3/en not_active Expired - Lifetime
- 2002-10-28 SI SI200230172T patent/SI1441769T1/en unknown
- 2002-10-28 ME MEP-346/08A patent/MEP34608A/en unknown
- 2002-10-28 AR ARP020104078A patent/AR037047A1/en not_active Application Discontinuation
- 2002-10-28 DE DE60204584T patent/DE60204584T2/en not_active Expired - Lifetime
-
2004
- 2004-04-19 ZA ZA2004/02943A patent/ZA200402943B/en unknown
- 2004-04-19 IL IL161512A patent/IL161512A/en not_active IP Right Cessation
- 2004-04-29 MA MA27664A patent/MA26289A1/en unknown
- 2004-05-26 NO NO20042199A patent/NO20042199L/en not_active Application Discontinuation
- 2004-05-27 HR HR20040480A patent/HRP20040480B1/en not_active IP Right Cessation
- 2004-08-12 HK HK04106057A patent/HK1063290A1/en not_active IP Right Cessation
-
2010
- 2010-07-02 JP JP2010152148A patent/JP2010248232A/en active Pending
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