PA8675801A1 - Anticuerpos anti-mcp-1, composiciones, metodos y usos - Google Patents

Anticuerpos anti-mcp-1, composiciones, metodos y usos

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Publication number
PA8675801A1
PA8675801A1 PA20068675801A PA8675801A PA8675801A1 PA 8675801 A1 PA8675801 A1 PA 8675801A1 PA 20068675801 A PA20068675801 A PA 20068675801A PA 8675801 A PA8675801 A PA 8675801A PA 8675801 A1 PA8675801 A1 PA 8675801A1
Authority
PA
Panama
Prior art keywords
mcp
methods
compositions
antibodies
plantes
Prior art date
Application number
PA20068675801A
Other languages
English (en)
Inventor
Anuk Das
Raymond Sweet
Ping Tsui
Michael Bardroff
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of PA8675801A1 publication Critical patent/PA8675801A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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Abstract

LA PRESENTE INVENCIÓN SE REFIERE A UN NUEVO ANTICUERPO ANTI-MCP-1, QUE INCLUYE ÁCIDOS NUCLEICOS AISLADOS QUE CODIFICAN POR LO MENOS UN ANTICUERPO ANTI-MCP-1, MCP-1, VECTORES, CÉLULAS HUÉSPED, ANIMALES O PLANTAS TRANSGÉNICAS, Y MÉTODOS PARA PREPARAR Y USAR A ESTOS, QUE INCLUYEN COMPOSICIONES, MÉTODOS Y DISPOSITIVOS TERAPÉUTICOS
PA20068675801A 2005-05-19 2006-05-18 Anticuerpos anti-mcp-1, composiciones, metodos y usos PA8675801A1 (es)

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EP2170387A4 (en) * 2007-06-29 2011-01-19 Centocor Ortho Biotech Inc ANTI-MCP-1 ANTIBODIES, COMPOSITIONS, METHODS AND USES
NZ591187A (en) * 2008-08-20 2012-07-27 Probiodrug Ag Antibodies directed against pyroglutamate monocyte chemoattractant protein-1 (mcp-1 n1pe)
MX2012002993A (es) 2009-09-11 2012-04-19 Probiodrug Ag Derivados heterociclicos como inhibidores de ciclasa glutaminilo.
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
JP5688745B2 (ja) 2010-03-10 2015-03-25 プロビオドルグ エージー グルタミニルシクラーゼ（ｑｃ、ｅｃ２．３．２．５）の複素環阻害剤
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ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
EP2852411A4 (en) * 2012-05-22 2016-01-13 Shire Human Genetic Therapies ANTI-CCL2 ANTIBODIES FOR THE TREATMENT OF SCLEROMERMIA
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DK3050574T3 (da) 2015-01-28 2020-01-20 Univ Bordeaux Anvendelse af plerixafor til behandling og/eller forebyggelse af akutte forværringer af kronisk obstruktiv lungesygdom
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CA3135694A1 (en) 2019-04-17 2020-10-22 Hiroshima University Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination
CA3164818A1 (en) * 2019-12-18 2021-06-24 F. Hoffmann-La Roche Ag Bispecific anti-ccl2 antibodies
CN112358547A (zh) * 2020-09-30 2021-02-12 浙江大学 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用
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JP2008546374A (ja) 2008-12-25
EA200702532A1 (ru) 2008-06-30
CN101511869A (zh) 2009-08-19
NZ563516A (en) 2011-04-29
AU2010202813A1 (en) 2010-07-22
AR053470A1 (es) 2007-05-09
CA2609349C (en) 2012-10-30
ES2438193T3 (es) 2014-01-16
WO2006125202A3 (en) 2009-05-07
KR20080012968A (ko) 2008-02-12
EA014229B1 (ru) 2010-10-29
AU2006247034B2 (en) 2010-12-02
CR9606A (es) 2010-08-18
CA2609349A1 (en) 2006-11-23
EP1888114A2 (en) 2008-02-20
MX2007014610A (es) 2008-04-14
WO2006125202A2 (en) 2006-11-23
AU2010202813B2 (en) 2011-11-03
BRPI0613164A2 (pt) 2010-12-21
EP1888114A4 (en) 2010-02-24
NO20076563L (no) 2008-02-05
IL187459A0 (en) 2008-03-20
EP1888114B1 (en) 2013-09-18
PE20110071A1 (es) 2011-01-31
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