PA8577201A1 - 3-fenil-propionamido, 3-fenil-acrilamido y derivados 3-fenil-propinamido como inhibidores de mao-b - Google Patents
3-fenil-propionamido, 3-fenil-acrilamido y derivados 3-fenil-propinamido como inhibidores de mao-bInfo
- Publication number
- PA8577201A1 PA8577201A1 PA20038577201A PA8577201A PA8577201A1 PA 8577201 A1 PA8577201 A1 PA 8577201A1 PA 20038577201 A PA20038577201 A PA 20038577201A PA 8577201 A PA8577201 A PA 8577201A PA 8577201 A1 PA8577201 A1 PA 8577201A1
- Authority
- PA
- Panama
- Prior art keywords
- phenyl
- propionamide
- derivatives
- acrylamid
- mao
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Abstract
3-FENIL-PROPIONAMIDO, 3-FENIL-ACRILAMIDO Y DERIVADOS DE 3-FENIL-PROPIONAMIDO, PROCESOS PARA SU PREPARACION, COMPOSICIONES QUE LOS CONTIENEN Y EL USO DE TALES DERIVADOS COMO INHIBIDORES DE MAO-B.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02015583 | 2002-07-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8577201A1 true PA8577201A1 (es) | 2004-02-07 |
Family
ID=30011071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20038577201A PA8577201A1 (es) | 2002-07-15 | 2003-07-10 | 3-fenil-propionamido, 3-fenil-acrilamido y derivados 3-fenil-propinamido como inhibidores de mao-b |
Country Status (20)
Country | Link |
---|---|
US (1) | US6900354B2 (es) |
EP (1) | EP1523469B1 (es) |
JP (1) | JP4108679B2 (es) |
KR (1) | KR20050029206A (es) |
CN (1) | CN1305838C (es) |
AR (1) | AR040489A1 (es) |
AT (1) | ATE410407T1 (es) |
AU (1) | AU2003281030B2 (es) |
BR (1) | BR0312658A (es) |
CA (1) | CA2493372A1 (es) |
DE (1) | DE60323981D1 (es) |
ES (1) | ES2314219T3 (es) |
MX (1) | MXPA05000583A (es) |
PA (1) | PA8577201A1 (es) |
PE (1) | PE20040667A1 (es) |
PL (1) | PL373390A1 (es) |
RU (1) | RU2318802C2 (es) |
TW (1) | TW200404760A (es) |
UY (1) | UY27894A1 (es) |
WO (1) | WO2004007429A1 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1588704A1 (en) * | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
MY149038A (en) * | 2004-05-26 | 2013-07-15 | Eisai R&D Man Co Ltd | Cinnamide compound |
KR20070083781A (ko) * | 2004-10-26 | 2007-08-24 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신나미드 화합물의 비정질체 |
RU2007129642A (ru) | 2005-02-25 | 2009-03-27 | Ф.Хоффманн-Ля Рош Аг (Ch) | Таблетки с улучшенным распределением лекарственного вещества |
WO2006127133A2 (en) | 2005-04-01 | 2006-11-30 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
US8138209B2 (en) * | 2005-07-13 | 2012-03-20 | Jenrin Discovery, Inc. | Substituted picolinamides as MAO-B inhibitors useful for treating obesity |
PL209602B1 (pl) | 2005-10-20 | 2011-09-30 | Inst Chemii Bioorg Pan | Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego |
JPWO2007058304A1 (ja) * | 2005-11-18 | 2009-05-07 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | シンナミド化合物の塩またはそれらの溶媒和物 |
EP1950211A4 (en) * | 2005-11-18 | 2011-08-31 | Eisai R&D Man Co Ltd | PROCESS FOR PREPARING A CINEMA ACID AMID DERIVATIVE |
CN101312965B (zh) * | 2005-11-24 | 2011-07-20 | 卫材R&D管理有限公司 | 吗啉型肉桂酰胺化合物 |
BRPI0618814A2 (pt) * | 2005-11-24 | 2014-04-29 | Eisai R&D Man Co Ltd | Composto ou um sal farmacologicamente aceitável do mesmo, e, agente farmacêutico |
TWI370130B (en) * | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
AR062095A1 (es) * | 2006-07-28 | 2008-10-15 | Eisai R&D Man Co Ltd | Profarmaco de compuesto cinamida |
US20080207900A1 (en) * | 2007-02-28 | 2008-08-28 | Teiji Kimura | Two cyclic oxomorphorin derivatives |
CA2687262A1 (en) * | 2007-05-16 | 2008-11-20 | Naoyuki Shimomura | One-pot production process for cinnamide derivative |
US7986144B2 (en) * | 2007-07-26 | 2011-07-26 | Schlumberger Technology Corporation | Sensor and insulation layer structure for well logging instruments |
CL2008002542A1 (es) | 2007-08-31 | 2009-01-02 | Eisai R&D Man Co Ltd | Compuestos derivados de imidazolil piridina ligados a un heterociclo mediante un vinilo, moduladores de la actividad de amiloide-beta; composicion farmaceutica que comprende a dichos compuestos; y su uso para el tratamiento de enfermedades tales como alzheimer, demencia, sindrome de down o amiloidosis. |
US7935815B2 (en) * | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
EP2239265A1 (en) * | 2008-01-28 | 2010-10-13 | Eisai R&D Management Co., Ltd. | Crystalline cinnamide compounds or salts thereof |
NL2005655A (en) | 2009-12-09 | 2011-06-14 | Asml Netherlands Bv | A lithographic apparatus and a device manufacturing method. |
CN104030941B (zh) * | 2014-06-23 | 2016-04-27 | 常州大学 | 一种3-(4-羟基苯基)丙酰胺的合成方法 |
CN107011313B (zh) * | 2016-01-27 | 2021-11-30 | 天士力医药集团股份有限公司 | 取代桂皮酰胺衍生物在制备抗焦虑药物中的应用 |
KR20200108015A (ko) | 2018-01-10 | 2020-09-16 | 브라이트씨드, 인크. | 대사를 조절하기 위한 방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2645019A1 (es) * | 1989-03-30 | 1990-10-05 | Fournier Innovation Synergie | |
US5679715A (en) | 1995-06-07 | 1997-10-21 | Harris; Richard Y. | Method for treating multiple sclerosis |
JP3258027B2 (ja) | 1996-03-15 | 2002-02-18 | サマーセット・ファーマシューティカルズ・インコーポレイテッド | セレジリン投与による末梢ニューロパシーの予防および治療方法 |
AU1359801A (en) | 1999-11-05 | 2001-06-06 | Vela Pharmaceuticals Inc. | Methods and compositions for treating reward deficiency syndrome |
-
2003
- 2003-07-03 US US10/613,785 patent/US6900354B2/en not_active Expired - Fee Related
- 2003-07-07 CA CA002493372A patent/CA2493372A1/en not_active Abandoned
- 2003-07-07 BR BR0312658-7A patent/BR0312658A/pt not_active IP Right Cessation
- 2003-07-07 JP JP2004520497A patent/JP4108679B2/ja not_active Expired - Fee Related
- 2003-07-07 WO PCT/EP2003/007231 patent/WO2004007429A1/en active Application Filing
- 2003-07-07 ES ES03740425T patent/ES2314219T3/es not_active Expired - Lifetime
- 2003-07-07 CN CNB038160579A patent/CN1305838C/zh not_active Expired - Fee Related
- 2003-07-07 MX MXPA05000583A patent/MXPA05000583A/es active IP Right Grant
- 2003-07-07 KR KR1020057000637A patent/KR20050029206A/ko not_active Application Discontinuation
- 2003-07-07 DE DE60323981T patent/DE60323981D1/de not_active Expired - Fee Related
- 2003-07-07 RU RU2005104104/04A patent/RU2318802C2/ru not_active IP Right Cessation
- 2003-07-07 PL PL03373390A patent/PL373390A1/xx unknown
- 2003-07-07 AT AT03740425T patent/ATE410407T1/de not_active IP Right Cessation
- 2003-07-07 AU AU2003281030A patent/AU2003281030B2/en not_active Ceased
- 2003-07-07 EP EP03740425A patent/EP1523469B1/en not_active Expired - Lifetime
- 2003-07-10 PA PA20038577201A patent/PA8577201A1/es unknown
- 2003-07-11 AR AR20030102502A patent/AR040489A1/es not_active Application Discontinuation
- 2003-07-14 UY UY27894A patent/UY27894A1/es not_active Application Discontinuation
- 2003-07-15 TW TW092119275A patent/TW200404760A/zh unknown
- 2003-07-15 PE PE2003000706A patent/PE20040667A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2318802C2 (ru) | 2008-03-10 |
PL373390A1 (en) | 2005-08-22 |
CN1665774A (zh) | 2005-09-07 |
PE20040667A1 (es) | 2004-09-25 |
US6900354B2 (en) | 2005-05-31 |
JP2005533092A (ja) | 2005-11-04 |
AU2003281030B2 (en) | 2009-05-28 |
DE60323981D1 (de) | 2008-11-20 |
BR0312658A (pt) | 2005-04-26 |
TW200404760A (en) | 2004-04-01 |
CA2493372A1 (en) | 2004-01-22 |
MXPA05000583A (es) | 2005-04-19 |
ATE410407T1 (de) | 2008-10-15 |
JP4108679B2 (ja) | 2008-06-25 |
AU2003281030A1 (en) | 2004-02-02 |
UY27894A1 (es) | 2003-12-31 |
WO2004007429A1 (en) | 2004-01-22 |
RU2005104104A (ru) | 2005-10-10 |
ES2314219T3 (es) | 2009-03-16 |
EP1523469A1 (en) | 2005-04-20 |
CN1305838C (zh) | 2007-03-21 |
AR040489A1 (es) | 2005-04-06 |
US20040034096A1 (en) | 2004-02-19 |
KR20050029206A (ko) | 2005-03-24 |
EP1523469B1 (en) | 2008-10-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY27894A1 (es) | Derivados de cinamida. | |
UY28342A1 (es) | Nuevos compuestos | |
ECSP077316A (es) | Compuestos imidazo-3-il-amina bicíclicos sustituidos | |
ECSP077271A (es) | Derivados de pirimidina | |
ECSP077259A (es) | Derivados de pirimidina | |
GT200500275A (es) | Nuevos herbicidas | |
CL2008002430A1 (es) | Compuestos derivados de bencenosulfonamida, inhibidores de catepsina c; composicion farmaceutica que los comprende; y su uso para el tratamiento de la epoc. | |
CO6321189A2 (es) | Compuestos de tiazol y oxazol de bencen-sulfonamida | |
NI201000055A (es) | 2' - fluoro - 2' - desoxitetrahidrouridinas como inhibidores de citidina desaminasa. | |
UY29781A1 (es) | Compuestos diazaspiro sustituidos, sales farmacéuticamente aceptables, composiciones farmacéuticas que contienen los compuestos o sales, métodos de preparación y usos | |
UY28572A1 (es) | Compuestos novedosos | |
ECSP055671A (es) | Nuevas quinazolinonas espirocondensadas y su uso como inhibidores de la fosfodiesteresa | |
CR9786A (es) | Compuestos de bencimidazol-tiofeno | |
ECSP034830A (es) | Derivados sustituidos de la ciclohexano-1,4- diamina | |
UY30976A1 (es) | Nuevos derivados de quinolina, composiciones farmaccuticas que los contienen, procesos de preparacion y aplicaciones. | |
UY29732A1 (es) | Derivados de benzotiazolonas, procesos de preparación, composiciones y combinaciones que los contienen y aplicaciones | |
HN1999000106A (es) | Compuestos heterociclicos como inhibidores de enzimas de rotamasa. | |
DOP2010000134A (es) | Algunos derivados de 2-pirazinona como inhibidores de elastasa de los neutrofilos | |
UY29607A1 (es) | Compuestos quimicos | |
ECSP11011344A (es) | Nuevos anticuerpos anti-?5?1 y sus usos | |
UY29003A1 (es) | Nuevos derivados de hidantoína, procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en terapia | |
ECSP088584A (es) | Nuevos derivados de benzimidazol como inhibidores del receptor vanilloide 1 (vrl) | |
GT201000047A (es) | Mejoras en compuestos organicos o relacionadas con los mismos | |
UY28670A1 (es) | Arilpirazoles sustituidos | |
GT200600123A (es) | Derivados de tetrahidronaftalina, procedimientos para su preparacion y su uso como inhibidor de la inflamacion |