OA21045A - Laminarin based formulation for agricultural applications - Google Patents
Laminarin based formulation for agricultural applications Download PDFInfo
- Publication number
- OA21045A OA21045A OA1202200411 OA21045A OA 21045 A OA21045 A OA 21045A OA 1202200411 OA1202200411 OA 1202200411 OA 21045 A OA21045 A OA 21045A
- Authority
- OA
- OAPI
- Prior art keywords
- composition
- laminarin
- polyol
- fongicides
- amount
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 128
- 239000005717 Laminarin Substances 0.000 title claims abstract description 71
- 229920001543 Laminarin Polymers 0.000 title claims abstract description 71
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 title claims abstract description 70
- 238000009472 formulation Methods 0.000 title description 13
- 229920005862 polyol Polymers 0.000 claims abstract description 48
- 150000003077 polyols Chemical class 0.000 claims abstract description 45
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 27
- 238000000034 method Methods 0.000 claims abstract description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 32
- 239000007788 liquid Substances 0.000 claims description 22
- 239000000417 fungicide Substances 0.000 claims description 18
- 230000000855 fungicidal effect Effects 0.000 claims description 16
- 235000011187 glycerol Nutrition 0.000 claims description 13
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 11
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims description 8
- 239000005864 Sulphur Substances 0.000 claims description 8
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 7
- 239000010949 copper Substances 0.000 claims description 7
- 229910052802 copper Inorganic materials 0.000 claims description 7
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 claims description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- DKVNPHBNOWQYFE-UHFFFAOYSA-N carbamodithioic acid Chemical compound NC(S)=S DKVNPHBNOWQYFE-UHFFFAOYSA-N 0.000 claims description 6
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 6
- 239000012990 dithiocarbamate Substances 0.000 claims description 6
- 239000003755 preservative agent Substances 0.000 claims description 6
- 239000004094 surface-active agent Substances 0.000 claims description 6
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 4
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 claims description 4
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 claims description 4
- NAYYNDKKHOIIOD-UHFFFAOYSA-N phthalamide Chemical compound NC(=O)C1=CC=CC=C1C(N)=O NAYYNDKKHOIIOD-UHFFFAOYSA-N 0.000 claims description 4
- NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical compound NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 claims description 4
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- 238000002156 mixing Methods 0.000 claims description 3
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- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- 229930195725 Mannitol Natural products 0.000 claims description 2
- ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 claims description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 2
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 claims description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 2
- 239000000594 mannitol Substances 0.000 claims description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 2
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- 235000010356 sorbitol Nutrition 0.000 claims description 2
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000000811 xylitol Substances 0.000 claims description 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 2
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- 238000003860 storage Methods 0.000 description 19
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- 239000000047 product Substances 0.000 description 7
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- 239000002253 acid Substances 0.000 description 5
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- 241000196324 Embryophyta Species 0.000 description 4
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- 150000001875 compounds Chemical class 0.000 description 4
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- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 3
- 241000199919 Phaeophyceae Species 0.000 description 3
- 240000003768 Solanum lycopersicum Species 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 239000003905 agrochemical Substances 0.000 description 3
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- 235000013399 edible fruits Nutrition 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
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- 239000002917 insecticide Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 3
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 description 2
- KJPRLNWUNMBNBZ-UHFFFAOYSA-N 3-phenylprop-2-enal Chemical compound O=CC=CC1=CC=CC=C1 KJPRLNWUNMBNBZ-UHFFFAOYSA-N 0.000 description 2
- PLLBRTOLHQQAQQ-UHFFFAOYSA-N 8-methylnonan-1-ol Chemical compound CC(C)CCCCCCCO PLLBRTOLHQQAQQ-UHFFFAOYSA-N 0.000 description 2
- 241001465180 Botrytis Species 0.000 description 2
- 235000002568 Capsicum frutescens Nutrition 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 244000304337 Cuminum cyminum Species 0.000 description 2
- 235000007129 Cuminum cyminum Nutrition 0.000 description 2
- 241000221785 Erysiphales Species 0.000 description 2
- 241000925440 Erysiphe sp. Species 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
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- AUZONCFQVSMFAP-UHFFFAOYSA-N disulfiram Chemical compound CCN(CC)C(=S)SSC(=S)N(CC)CC AUZONCFQVSMFAP-UHFFFAOYSA-N 0.000 description 2
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- LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 description 1
- YIKWKLYQRFRGPM-UHFFFAOYSA-N 1-dodecylguanidine acetate Chemical compound CC(O)=O.CCCCCCCCCCCCN=C(N)N YIKWKLYQRFRGPM-UHFFFAOYSA-N 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- OTWBGXPTCSGQEJ-UHFFFAOYSA-N 2-[(dimethylcarbamothioyldisulfanyl)carbothioylamino]ethylcarbamothioylsulfanyl n,n-dimethylcarbamodithioate Chemical compound CN(C)C(=S)SSC(=S)NCCNC(=S)SSC(=S)N(C)C OTWBGXPTCSGQEJ-UHFFFAOYSA-N 0.000 description 1
- AGNTUZCMJBTHOG-UHFFFAOYSA-N 3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]propane-1,2-diol Chemical compound OCC(O)COCC(O)COCC(O)CO AGNTUZCMJBTHOG-UHFFFAOYSA-N 0.000 description 1
- WOKDXPHSIQRTJF-UHFFFAOYSA-N 3-[3-[3-[3-[3-[3-[3-[3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]propane-1,2-diol Chemical compound OCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)CO WOKDXPHSIQRTJF-UHFFFAOYSA-N 0.000 description 1
- BFTGQIQVUVTBJU-UHFFFAOYSA-N 5,6-dihydroimidazo[2,1-c][1,2,4]dithiazole-3-thione Chemical compound C1CN2C(=S)SSC2=N1 BFTGQIQVUVTBJU-UHFFFAOYSA-N 0.000 description 1
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- 239000008103 glucose Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 150000001469 hydantoins Chemical class 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000012263 liquid product Substances 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- YKSNLCVSTHTHJA-UHFFFAOYSA-L maneb Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S YKSNLCVSTHTHJA-UHFFFAOYSA-L 0.000 description 1
- 229920000940 maneb Polymers 0.000 description 1
- HYVVJDQGXFXBRZ-UHFFFAOYSA-N metam Chemical compound CNC(S)=S HYVVJDQGXFXBRZ-UHFFFAOYSA-N 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 229920000257 metiram Polymers 0.000 description 1
- UQJQVUOTMVCFHX-UHFFFAOYSA-L nabam Chemical compound [Na+].[Na+].[S-]C(=S)NCCNC([S-])=S UQJQVUOTMVCFHX-UHFFFAOYSA-L 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- XKJCHHZQLQNZHY-UHFFFAOYSA-N phthalimide Chemical compound C1=CC=C2C(=O)NC(=O)C2=C1 XKJCHHZQLQNZHY-UHFFFAOYSA-N 0.000 description 1
- 239000000280 phytoalexin Substances 0.000 description 1
- 150000001857 phytoalexin derivatives Chemical class 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- KKMLIVYBGSAJPM-UHFFFAOYSA-L propineb Chemical compound [Zn+2].[S-]C(=S)NC(C)CNC([S-])=S KKMLIVYBGSAJPM-UHFFFAOYSA-L 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 235000021309 simple sugar Nutrition 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 108020001568 subdomains Proteins 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- LITQZINTSYBKIU-UHFFFAOYSA-F tetracopper;hexahydroxide;sulfate Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Cu+2].[Cu+2].[Cu+2].[Cu+2].[O-]S([O-])(=O)=O LITQZINTSYBKIU-UHFFFAOYSA-F 0.000 description 1
- JYKSTGLAIMQDRA-UHFFFAOYSA-N tetraglycerol Chemical compound OCC(O)CO.OCC(O)CO.OCC(O)CO.OCC(O)CO JYKSTGLAIMQDRA-UHFFFAOYSA-N 0.000 description 1
- 229960002447 thiram Drugs 0.000 description 1
- KUAZQDVKQLNFPE-UHFFFAOYSA-N thiram Chemical compound CN(C)C(=S)SSC(=S)N(C)C KUAZQDVKQLNFPE-UHFFFAOYSA-N 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Abstract
The present invention relates to a composition comprising water soluble actives such as laminarin. Particularly, the present invention relates to a stable composition comprising water soluble actives such as laminarin and a polyol. The present invention also relates to a process for the preparation of said composition and method of use thereof.
Description
LAMINARIN BASED FORULATION FOR AGRICULTURAL APPLICATIONS
Field of invention
The présent invention relates to a composition comprising water soluble actives.
The présent invention also relates to a proeess for the préparation of said s composition and method of use thereof.
Background of the invention
Laminarin is a polysaccharide derived from seaweed, a polymer of simple sugars linked together by glycosidic bonds. More specifically, it is a class of storage βglucans comprised of 8-(1-3)-linked glucose residues with some β-(1 -6)-intrachain 10 linkages, and some 6-0-branching in the main chain. D-mannitol occurs at 2-3% of reducing termini and these chains are referred to as M chains, while those with glucose at the reducing termini are known as G chains. The exact molecular structure of laminarin varies depending on environ mental factors such as water température, salinity and nutrient salts, waves, sea current and immersion depth. 15 Its Chemical formula is CibHsïOie (University of Hertfordshire 2014; ChEBI 2015;
Kadam, Tiwari and O'Donnell 2015).
Brown algae may contain up to 35% laminarin on a dry weight basis, depending on species, season, habitat and extraction method. Laminarin is generally 20 extracted from brown algae of the Pheophyceae type, and in particular the Focales or the Laminariales. Laminarin is known to use as a seed germination and plant growth accelerator (biostimulant).
Laminarin can be extracted starting from a raw matehal consistîng of brown algae, especially using the method disclosed in the French patent FR 9208387. The formulated product (Vacciplant) for laminarin (EPA registered) contains 3.51%
laminarin as the active ingrédient, surfactant (<10%) and two different preservatives (each <1%) that are permitted for use as food additives,
Various scientific publications describe the properties of laminarin, suggesting its use for enhancing plant defense reactions.
NETZER étal, reveal thatan infection with the pathogen S. oxysporum triggersthe induction of laminarinase (Biological abstracts, vol. 68, no. 1, 1979).
BONHOFF et al. reveal the properties of laminarin as an elicitor of phytoalexin and callose (Biological abstracts, vol. 86, no. 4, 1988).
KUROSAKI et al. (Biological abstracts, vol. 85, no. 2, 1988) and PEARCE 10 (Biological abstracts, vol. 74, no. 8, 1982) confirm the eliciting effects of laminarin, in particular in respect of lignification, while at the same time stating that these effects are weak compared with those of the known elicitors.
The challenge involved in developing commercially acceptable products containing agriculturally active compounds continues to increase due to the rapid emergence 15 of more complex customer and regulatory requirements. These agricultural compositions must exhibit excellent chemioal stability and must also maintain a high level of physical stability under a severe range of storage and use conditions. Handling of a liquid product in bulk storage facilities represents a spécial challenge because the product can be subject to high shear forces at both high and low 20 températures. This emerging area of performance is critioal to customer satisfaction and commercial success with a product. At the same time the demand on the agrochemical composition performance has been încreasing, the number of auxiliary Chemicals approved for use in agrochemical compositions by the various regulatory authorities has been decreasing due to more stringent 25 standards for the toxicological and ecological properties of these materials.
The agrochemical compositions are generally prepared using one or more adjuvants sometimes in spécifie combinations to provide optimum biological activity. Sometimes the stability of the formulation may be disturbed, and one or more component séparâtes oui, for example as a discrète phase. 1n general, the 30 séparation of a discrète phase from an agrochemical is highly undesirable, particularly when the formulation is sold in bulk containers. In these circumstances
it is virtuafly impossible to re-homogenize the formulation and to achieve even distribution of the components for application. Furthermore, the formulation must be stable in respect of storage for prolonged péri ods in both hot and cold climates. These ail factors présent formidable problems to the formulator.
s There is a need in the art for solvent system to develop a formulation that has both unique performance characteristics and a good physicochemical stability.
Advantages of the Invention:
It is an advantage of the présent invention to provide a composition comprisîng a water soluble active which is devoid of any haziness or phase séparation and 10 imparts good stability to the final product even at low températures.
Yet another advantage of the invention is a composition of water soluble active having enhanced bioefficacy.
Further advantage of the présent invention is a process for preparing a formulation comprisîng a water soluble active alone or in combination as described herein in 15 this spécification.
Yet another advantage of the présent invention a composition that exhibits excellent Chemical and physical stability under a severe range of storage and use conditions.
These and other advantages of the présent invention would be apparent from the 20 description of the invention set out hereinafter.
Summary of the Invention
Accordingly, in one aspect, the présent invention provides a composition comprisîng:
i) a water soluble active ingrédient; and ii) a polyol.
In another aspect the présent invention provides a composition comprisîng:
i) laminarin; and ii) a polyol.
In another aspect the présent invention provides a stable liquid composition comprising:
i) laminarin; and ii) a polyol.
In another aspect the présent invention provides an aqueous composition comprising:
i) laminarin; and ii) a polyol.
In another aspect, the présent invention relates te an improved composition comprising laminarin as a bio stimulant and process for preparing said composition.
In yet another aspect, the présent invention provides a method for use of said composition comprising applying a composition according to the présent invention at the desired location.
In another aspect, the présent invention provides a kit comprising stable composition according to the présent invention as a biopesticide.
Detailed Description of the Invention
For the purposes of the foilowing detailed description, it is to be understood that the invention may assume various alternative variations and step sequences, except where expressly specified to the contrary. Moreover, other than in any operating examples, or where otherwise indicated, ail numbers expressing, for example, quantifies of materials/ingredients used in the spécification are to be understood as being modified in ail instances by the term about.
Thus, before describing the présent invention in detail, it is to be understood that this invention is not limited to particularly exemplified Systems or process parameters that may of course, vary, It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this spécification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this spécification. Unless otherwise defined, ail technical and scientific terms used herein hâve the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including définitions will control.
It must be noted that, as used in this spécification, the singular forms “a, “an” and “the include plural referents unless the content clearly dictâtes otherwise. The terms preferred” and “preferably” refer to embodiments of the invention that may afford certain benefits, under certain circumstances.
As used herein, the terms “comprising “including,” “having, “containing,” “involving,” and the like are to be understood to be open-ended, i.e., to mean including but not limited to.
The present inventors hâve surprisingly found that when polyol as solvent present in the composition comprising a water soluble active provides stable formulation. Preferably, the composition according to the present invention is an aqueous formulation, Accordingly, the present invention provides a composition comprising water soluble active agent and polyol as solvent. It has been found that a composition comprising polyol as solvent along with active ingrédient is physicochemically stable even after a prolonged storage at different conditions.
Accordingly, in one aspect, the present invention provides a composition comprising;
i) a water soluble active ingrédient; and ii) a polyol.
In an embodiment the water soluble active is laminarin.
It has been known that laminarin and compositions in which it is present increase the production yield of agricultural products by exerting an accéléraiing action on plant growth, cell élongation and seed germination.
Advantageously, the composition may contain from 0.005 to 600 parts by weight of laminarin and preferably from 1 to 250 parts by weight when it is in solid form, and from 0.005 to 100 parts by weight of laminarin when it is in liquid form.
In an embodiment, the present invention provides a liquid composition comprising 5 from about 0.005 to 100 parts by weight of laminarin.
In an embodiment, the present invention provides a liquid composition comprising from about 0.5 to 100 parts by weight of laminarin.
In an embodiment, the present invention provides a liquid composition comprising from about 1 to 80 parts by weight of laminarin.
In an embodiment, the present invention provides a liquid composition comprising from about 10 to 50 parts by weight of laminarin.
In an embodiment, the parts refer to the parts by weight of the composition in grams.
In an embodiment, the present invention provides a liquid composition comprising 15 about 37g by weight of laminarin.
In an embodiment, the present invention provides a liquid composition comprising about 45g by weight of laminarin.
In an embodiment, the composition may comprise about 46.8% by total weight of laminarin.
In an embodiment, the composition may comprise about 57% by total weight of laminarin.
As used herein, the term polyol includes any compound having at least one hydroxyl group on each of two adjacent carbon atoms that are not in trans configuration relative to each other. The polyols can be acyclic or cyclic, substituted 25 or unsubstituted, or mixtures thereof, so long as the résultant complex is water soluble and agrochemically acceptable.
In an embodiment, the present composition comprises at least one polyol and the polyol is selected from acyclic polyol and cyclic polyol.
Examples of such polyol compounds include: sugars, sugar alcohols, sugar acids and uronic acids. Preferred polyols are sugars, sugar alcohols and sugar acids, including, but not limited to: mannitol, giycerin, xylitol and sorbitol. Especially preferred polyol is giycerin.
In an embodiment, polyol can be selected from ethylene glycol, propylene glycol, butylène glycol, diethylene glycol, triethylene glycol, dipropylene glycol, glycerol and trimethylolpropane.
Other polyols for example diglycerol, triglycerol, tetraglycerol, pentaglycerol, hexaglycerol, heptaglycerol, octaglycerol, nonaglycerol, decaglycerol, 10 pentadecaglycerol, eicosaglycerol and triacontaglycerol and the like may also be used.
In one embodiment the polyol used in the présent invention is glycerol.
In an embodiment, the polyol is used in an amount from about 0.005 to 90% w/w of total composition.
In an embodiment, the polyol is used in an amount from about 1 to 70% w/w of total composition.
In an embodiment, the polyol total composition.
In an embodiment, the polyol total composition.
In an embodiment, the polyol is is used in used in is used in an an an amount from amount from about 1 about 1 amount from about 1 to 50% w/w of to 40% w/w of to 30% w/w of total composition.
In a preferred embodiment, the polyol is used in an amount from about 10 to 40% w/w of total composition.
In an embodiment, the polyol is used in an amount of about 35% w/w of total composition.
Accordingly, the présent invention provides a composition comprising an effective amount of laminarin and polyol in an amount from about 0.005 to 90% w/w of total composition.
Accordingly, the présent invention provides a composition comprising from about 0.005 to 600 grams by weight of laminarin and polyol in an amount from about 0.005 to 90% w/w of total composition.
In one embodiment, the présent invention provides an aqueous composition S comprising from about 0.005 to 600 grams by weight of laminarin and polyol in an amount from about 0.005 to 90% w/w of total composition.
An important advantage of the présent invention is that when polyol for example glycérine is used in the formulation it acts as a preservative, as well as inhibits laminarin crystal growth under 60-70O.
It was found that use of glycerin in laminarin formulations unexpectedly improve the laminarin soiubility in water-based formulations.
According to the présent invention there is no need to add thickener into Vacciplant® formulations (containing laminarin) to suspend laminarin particles over time.
Therefore, in an embodiment, the composition of the présent invention is substantially free of a thickener.
In another embodiment, préparation of a composition containing an effective amount of laminarin, optionally incorporated with an agriculturally acceptable carrier or vehicle.
In another embodiment, the composition can be presented in solid form, especially in the form of powders or granules, or in liquid form, especially in the form of aqueous solutions.
In another embodiment, the composition also contains at least one additional substance selected from deficiency-correcting éléments, fongicides, insecticides, 25 herbicides, growth hormones, lipoamino acids and betaines.
Another embodiment of the présent invention provides a composition comprising:
i) a water soluble active ingrédient;
ii) a polyol; and iii) at least one additional substance selected from deficiency-correcting éléments, fongicides, insecticides, herbicides, growth hormones, lipoamino acids and betaines.
In an embodiment, the additional substance is afungicide.
In an embodiment, the fongicide is a multi-site fongicide. The molti-site contact fongicide may be selected from copper fongicides, dithiocarbamate fongicides, phthalamide fongicides, chloronitrile fongicides, sulfamide fongicides, guanidine fongicides, triazines fongicides and qoinone fongicides.
In an embodiment, the additional sobstance is a copper fungicide. The copper 10 fongicides of the présent invention are inorganic compoonds containing copper, typically in the copper (II) oxidation State and are preferably selected from copper oxychloride, copper sulfate, copper hydroxide and tribasic copper sulfate (Bordeaux mixture).
In an embodiment, the additional substance is sulfur. The sulfur fongicides of the 15 présent invention are inorganic Chemicals containing rings or chains of sulfur atoms and is preferably elemental sulfur.
In an embodiment, the additional substance is a dithiocarbamate. The dithiocarbamate fongicides of the présent invention contain a dithiocarbamate molecular moiety and are selected from amobam, asomate, azithiram, 2û carbamorph, cufraneb, cuprobam, disulfiram, ferbam, metam, nabam, tecoram, thiram, urbacide, zlram, dazomet, etem, milneb, mancopper, mancozeb, maneb, metiram, polycarbamate, propineb and zineb.
In an embodiment, the additional sobstance is a phthalimide fungicide. The phthalamide fongicides of the présent invention contain a phthalamide molecolar 25 moiety and are selected from folpet, captan and captafol.
In an embodiment, the additional substance is a chloronitrile fungicide. The chloronitrile fongicide of the présent invention comprises an aromatic ring substituted with chlore- and cyano-substituents and is preferably chlorothalonil.
In an embodiment, the additional substance is a sulfamide fungicide. The 30 sulfamide fongicides of the présent invention are preferably selected from dichlofluanid and tolylfloanid.
In an embodiment, the additional substance is a guanidine fongicide. The guanidine fongicides of the present invention are preferably selected from dodine, guazantine and iminoctaadine.
in an embodiment, the additional substance is a triazine fungicide. The triazine 5 fungicide of the present invention is preferably anilazine.
In an embodiment, the additional substance is a quinone fungicide, The quinone fungicide of the présent invention is preferably dithianon.
In an embodiment, the additional substance is a cinnamaldéhyde.
Other examples of fongicides which can be osed are compounds belonging to the 10 group comprising hydantoins, imidazoles.or triazoles.
Examples of herbicides which can be used are compounds belonging to the group comprising carbamates, cyclohexadiones, sulfonylureas, triazines or uracils.
In general terms, the compositions according to the invention are prepared by mixing laminarin, extracted in powder form, with customary additives, for example 15 solid fillers and/or solvents.
In an embodiment, the composition of the present invention may contain agriculturally acceptable adjuvants, carriers, diluents, surfactants, surface-active substances, emulsifiers, fillers, anti-foaming agents, anti-freezing agents, freezing agents, preservatives etc.
Examples of solid fillers which can be used for the préparation of wettable powders or granules are fînely divided kaolin or clay.
When presented in liquid form, these compositions will preferably be obtained by diluting the laminarin in water.
It is also possible to préparé spraying compositions based on oi) or emulsifiable 25 concentrale (EC), especially in the case of a mixture with additional substances which are insoluble in water.
In another aspect the present invention provides a process for préparation of composition comprising mixing laminarin with polyol and water, preferably at room température.
In an embodiment, the process comprises adding optionally preservative or antifoaming agent for example DrewPlus L-768 or surfactant; heating the mixture obtained and cooling down at room température to obtain the final product.
The surfactant may be non-ionic alkoxylates selected from Cw-12 alcohol (10 EO) Ethoxylate, Tridecyi alcohol (6EO) Ethoxylate, Cio alcohol (5 EO) Ethoxylate, Ce alcohol Ethoxylate (4 EO), C9-11 alcohol Ethoxylate (4 EO), Isodecyl alcohol (7 EO) Ethoxylate or combination thereof. Preferred surfactant may be Dodecan-1-o ethoxylated (23EO).
The preservatives are optionally added such as, dérivatives of benzoic acid, sorbic acid, formaldéhyde, in particular potassium sorbate, a combination of methyl parahydroxybenzoate or propyl parahydroxybenzoate, generally in an amount from about 0.1% to about 1.0% w/w.
The antifoams/defoamers are optionally added in an amount from about 0.01% to about 2% w/w, preferably from about 0.1% to about 1,5% w/w of total weight of the composition.
The composition according to the présent invention comprises at least 5% by weight, preferably at least 10% by weight and especially preferably at least 15% by weight of water based on the total weight of the composition.
The composition according to the invention comprises from about 5% to about 70% w/w, preferably from about 10% to about 60% w/w and especially preferably from about 15% to about 50% w/w of water, based on the total weight of the composition.
Examples of plants which can be treated successfully with laminarin within the framework of the use according to the invention are selected from the group comprising, but not iimited to, fruit crops such as apple trees, pear trees and vines; cereals such as wheat, maize and rice; oleaginous plants such as soya, sunflower and colza; vegetables such as carrots, tomatoes, cauliflowers and potatoes.
In general, laminarin can be used in doses of between 0.005 g and 100 g per liter for treating the leaves, and of between 1 g and 100 g per 100 kg for treating the seeds.
In an embodiment, laminarin is applied with one another fungicide or an insecticide.
In an embodiment, laminarin is applied with a fungicide selected from the group consisiting of a dithiocarbamate fungicide, copper, sulphur and cinnamaldéhyde.
However, it should be understood that scope of the présent invention is not limited 5 by the examples in any manner. It will be appreciated by any person skilled in this art that the présent invention includes aforesaid examples and further can be modified and - altered within the technical scope of the présent invention. Consequently, the use of ranges of numbers expressly includes any possible subdomains and any other individual numeric values included in this range, and any 10 numeric values in these ranges or sub domains, together with any fractions of the said numeric values or said whole numbers within these ranges, unless the context expressly indicated otherwise. This applies in ail cîrcumstances to ali number ranges and in any context throughout this application. For example, a range of numbers from 10 to 60% includes 15 to 55%, 20-50%, 25-45%, 30-40% and so on.
While the foregoing written description of the invention enables one of ordinary skill to make and use what is considered presently to be the best mode thereof, those of ordinary skill will understand and appreciate the existence of variations, its combinations, and équivalents of the spécifie embodiment, method, and examples herein. The invention should therefore not be limited by the above described 20 embodiment, method, and examples, but by ail embodiments and methods within the scope and spirit of the invention.
The invention will be illustrated with reference to the following examples.
EXAMPLES
Example 1
| Ingrédients | Amount in percentage (%) |
| Laminarin (75 g/L) | 46.8 |
| Glycerin | 38.4 |
| Water | Q. S. |
| Total | 100 |
1. In a double jacketed vessel, laminarin technical, is mixed at room température with glycerin, water for 15 min.
2. The vessel is heated at 50-55°C. The mixture is stirred for 30 min at 5055°C.
3. After cooling down at room température, the product is then packed.
Example 2
| Ingrédients | Amount in percentage (%) |
| Laminarin (75 g/L) | 57 |
| Glycerin | 37.83 |
| Water | Q. S. |
| Total | 100 |
1. In a double jacketed vessel, laminarin technical is mixed at room 10 température with glycerin, water for 15 min.
2. The vessel is heated at 50-55°C. The mixture is stirred for 30 min at 5055Ό.
3. After cooling down at room température, the product is then packed.
Example 3
The compositions as described in example 1 and example 2 were tested for storage stability. The CIPAC (Collaborative International Pesticides Analytical Council) method studies samples stored at 54°C over a period of 2 weeks, 12Months at 25°C, SMonths at 40=0, 3Months at -10°C and 7 days at OC.
| Parameters | Conditions | Example 1 | Example 2 |
| Active substance | before storage | 39,5 g/L | 46,0 g/L |
| content | after storage 2 weeks at 54 °C | 38,0 g/L | 44,1 g/L |
| Appearance | before storage | Clear liquid | Clear liquid |
| after storage 2 weeks at 54 °C | Clear liquid | Clear liquid | |
| after storage 12Months atas-C | Clear liquid | Clear liquid | |
| after storage 3Months at 40,:C | Clear liquid | Clear liquid | |
| after storage SMonths at -1Û°C | Clear liquid | Clear liquid | |
| pH | before storage | 3.2 | 3.2 |
| after storage 2 weeks at 54 C | 3.1 | 3.0 | |
| Dilution stabîlity | before storage | Sample is 100% soluble with no séparation | Sample îs 100% soluble with no séparation |
| after storage 2 weeks at 54°C | No séparation, 100% soluble | No séparation, 100% soluble | |
| Low température stabîlity | 7 days at 0 °C | No crystallization after 7 days at OO | No crystallization after 7 days at 0°C |
AH the compositions prepared accordîng to the process disclosed in the present invention were found to possess good stabîlity profile. Further the formulations were stable at ail the tested températures for the described storage durations.
Example 4
Field trials:
Trials hâve been conducted ta demonstrate the efficiency of the present composition on Tomato Botrytis.
Details of experiment:
Application of composition- ABCDEF, A= early flowering, B= full flowering, C= end of flowering, then every 7-10 days.
Spray interval : 7-10 days // Spray volume : 600Uha, foliar spray.
Assessment on leaves: severity and incidence (%) at 0 DAA, 10 DAB, 10 DAC, 10 15 DAD, 10DAF, 30DAF .
Assessment on fruits ; severity and incidence (%) at 0 DAA, 10 DAB, 10 DAD, 10DAF, 30DAF + two on post-harvest
Phytotoxicity symptoms (%) at 0 DAA, 10DAB.10DAD, 10DAF.
Table 1 : Percent disease dimension
| Foliage | Fruits | |||||||
| % Incidence | % Severity | Intensity | % Incidence | |||||
| Treatment/dose | 10 DAC | 10 DAD | 10 DAC | 10 DAD | 10 DAC | 10 DAD | 10 DAC | 10 DAD |
| Formulation-1 3l/ha | 16 | 37 | 10 | 26 | 2 | 9 | 0 | 9 |
| Formulation-1 0,81/ha | 20 | 45 | 8 | 29 | 2 | 13 | 0 | 9 |
| Untreated | 39 | 64 | 22 | 59 | 9 | 38 | 0 | 39 |
It has been observed that for ail test results set out in above tables, this 10 composition shows good efficiency for control of Tomato Botrytis.
Example 5
Field trials:
Trials hâve been conducted to demonstrate the efficiency of the présent composition also comprising of sulphur against powdery mildew (Erysiphe sp.) in 15 Cumin.
Details of experiment:
The trials were carried out at 4 locations, post-emergent applications were done at an interval of 10 days. The crop was in a végétative growth State at the time of application.
A- first application
B - second application
Spray interval : 7-10 days // Spray volume : 500L/ha, foliar spray.
Assessment: severity and incidence (%) at 5 DA-A, 10 DA-A, 5 DA-B, 10DA-B and
Disease Control (%) at 5 DA-A, 10 DA-A, 5 DA-B, 10DA-B.
Table 2: Percent disease dimension in Cumin
| Treatment details | al Dose rate(g/ ha) | Form. Dose rate | Applic ation | ERVSSP (PDI) | ERYSSP (PDC) | |||||||
| (ml or g/ ha) | Timin gs | 5 DAA | 10 DA- A | 5 DA- B | 10 OA- B | 5 DA’ A | 10 ΟΛ- Α | 5 DA- B | 10 DA- B | |||
| LIntreated check | - | - | - | 16. 5 | 30.1 | 44. 5 | 67 | 0 | 0 | 0 | 0 | |
| Laminarin 45 SL + Sulphur 80% WDG | 45 | 2000 | 1000 4 2600 | AB | 39 | 9-8 | 7,9 | 17.3 | 76 | 66 | 82 | 74 |
| Laminarin 45 SL 4 Sulphur 80% WDG | 90 | 2000 | 2000 42500 | AB | 39 | 9.1 | 7,3 | 16.6 | 76 | 70 | 84 | 75 |
| Laminarin 45 SL 4 Su lpt1 ur 80 % WDG | 90 | 1600 | 2000 4 2000 | AB | 4.3 | 10.9 | 8-6 | 18.4 | 74 | 64 | 80 | 73 |
Example 6
Field trials:
Trials hâve been conducted to demonstrate the efficiency of the présent composition also comprising of copper oxychloride against citrus canker Xanthomonas campestris p.v. citriin citrus fruits lemon and kinnow.
Details of experiment:
Age of the plants was between 8-12 years.
replicates were made for the experiment conducted at 4 different locations.
applications were made with an interval of 7 days.
A- first application
B - second application
C- third application
D- fourth application
Spray interval : 10 days /! Spray volume ; lOUtree, foliar spray.
Assessment: severity and incidence (%) at 7 DA-A, 7 DA-B, 7 DA-C, 7DA-D and Disease Control (%) at 7 DA-A, 7 DA-B, 7 DA-C, 7DA-D.
Table 3: Percent disease dimension in Citrus
| Treatment details | ai. Dose raie | Form. Dose rate | XANTCI (PDI) | XANTCI (PDG) | |||||||
| (g/ L water) | (ml or S/ L water) | 7 DA- A | 7 DA- B | 7 DA- C | 7 DA- D | 7 DA- A | 7 DA- B | 7 DA- C | 7 DA- D | ||
| Untreated check | -- | 3.33 | 18.87 | 32.93 | 5661 | - | - | - | - | ||
| Laminarin 4.5% SL * Copper oxychloride 50% WP | 0.09 | 1 | 2.0+2.0 | 0 | 3.33 | 5.92 | 9.62 | 100 | 82.35 | 82.02 | 83.01 |
| Laminarin 4.5% SL + Copper oxychloride 50% WP | 0.11 | 1 | 2.5+2.0 | 0 | 2.96 | 5.55 | 8.51 | 100 | 84.31 | 83.15 | 84.97 |
Example 7
Field trials:
Trials hâve been conducted to demonstrate the efficiency of the present 10 composition also comprising of sulphur against powdery mildew (Erysiphe sp.) in Chili.
Details of experiment:
The trials were carried out at 3 locations.
post-emergent applications were done at an interval of 7 days. The crop was in 15 a végétative growth state at the time of application.
A- first application
B- second application
C- third application
Spray interval : 7 H Spray volume : SDOUha, foliar spray.
Assessment: severity and incidence (%) at 7 DA-A, 7 DA-B, 7 DA-C and Disease Control (%) at 7 DA-A, 7 DA-B, 7 DA-C.
Table 4: Percent disease dimension in Chili
| Treatment details | a.i. Dose rate (g/ ha J | Form. Dose rate (ml or g/ ha) | PDI | PDG | |||||
| 7 DA- A | 7 DA- B | 7 DAC | 7 DA- A | 7 DA- B | 7 DAC | ||||
| Untreated check | * | - | -- | 7.4 | 22.2 | 43.5 | 0 | 0 | 0 |
| Laminarin 4.5%SL + Suiphur80 WDG | 90 | 2000 | 2000 + 2500 | 2.7 | 7.9 | 13.9 | 63.1 | 64.5 | 68 |
| Laminarin 4.5%SL + Sulphur 80 WDG | 135 | 1600 | 3000 + 2000 | 3 | 8.4 | 15.4 | 59.5 | 62 | 64.5 |
| Laminarin 4.5%SL + Sulphur 80 WDG | 113 | 2000 | 2500 + 2500 | 2.4 | 7.1 | 11.7 | 67.5 | 67.5 | 73.5 |
It is évident from the above examples that the compositions of the présent invention are effective in controlling diseases in crops.
Claims (25)
1, A composition comprising:
i) laminarin; and ii) a polyol.
2, The composition as claimed in claim 1, wherein the said polyol is selected from the group consisting of mannitol, glycerin, xylitol, sorbitol, ethylene glycol, propylene glycol, butylène glycol, diethylene glycol, triethylene glycol, dipropylene glycol, and trimethylolpropane.
3. The composition as claimed in claim 2, wherein the said polyol is glycerin.
4. The composition as claimed in claim 1, wherein the said composition comprises 0.005 to 600 parts by weight of laminarin.
5. The composition as claimed in claim 1, wherein the said composition is in a liquid form.
6. The composition as claimed in claim 5, wherein the said composition comprises 0.005 to 100 parts by weight of laminarin.
7. The composition as claimed in claim 5, wherein the said composition comprises 1 to 80 parts by weight of laminarin.
8. The composition as claimed in claim 5, wherein the said composition comprises 10 to 50 parts by weight of laminarin.
9. The composition as claimed in claim 1, wherein the said polyol is used in an amount from about 0.005 to 90% w/w of total composition.
10. The composition as claimed in claim 5, wherein the said polyol is used in an amount from about 1 to 70% w/w of total composition.
11. The composition as claimed in claim 5, wherein the said polyol is used in an amount from about 1 to 50% w/w of total composition.
12. The composition as claimed in claim 5, wherein the said polyol is used in an amount from about 1 to 40% w/w of total composition.
13. The composition as claimed in claim 5, wherein the said polyol is used in an amount from about 1 to 30% w/w of total composition.
14. A stable composition comprising
i) Laminarin; and ii) a polyol in an amount from about 0.005 to 90% w/w of total composition.
15. A liquid composition comprising
i) Laminarin; and ii) Glycerol
16. The composition as claimed in claim 15, wherein the said composition comprises 0.005 to 600 parts by weight of laminarin and about 0.005 to 90% w/w glycerol of total composition.
17. A composition comprising:
i) Laminarin;
ii) a polyol; and iii) at least one fongicide
18. The composition as claimed in claim 17, wherein the said polyol is a glycerol présent in about 0.005 to 90% w/w glycerol of total composition.
19. The composition as claimed in claim 17, wherein the said fongicide is a multi-site fungicide selected from copper fongicides, dithiocarbamate fongicides, phthalamide fongicides, chloronitrile fongicides, sulfamide fungicides, guanidine fongicides, triazines fungioides and quinone fungicides.
20. The composition as claimed in claim 19, wherein the said fungicide is a sulphur fungicide.
21. The composition as claimed in claim 19, wherein the said fongicide is a copper fungicide.
22. A process for préparation of a stable composition comprising mixing laminarin with polyol and water, preferably at room température.
23. The process as claimed in claim 22, wherein the said process further comprises adding at least one ingrédient selected from the group
5 consisting of a preservative, an antifoaming agent and a surfactant.
24. A method of treating a plant comprising applying at a locus a composition comprising laminarin and a polyol.
25. A kit-of-parts comprising a component of laminarin, a component of polyol and optionally, another fungicide.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN202011017328 | 2020-04-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA21045A true OA21045A (en) | 2023-10-09 |
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