NZ772098A - 4-methylsulfonyl-substituted piperidine urea compounds for the treatment of dilated cardiomyopathy (dcm) - Google Patents
4-methylsulfonyl-substituted piperidine urea compounds for the treatment of dilated cardiomyopathy (dcm)Info
- Publication number
- NZ772098A NZ772098A NZ772098A NZ77209816A NZ772098A NZ 772098 A NZ772098 A NZ 772098A NZ 772098 A NZ772098 A NZ 772098A NZ 77209816 A NZ77209816 A NZ 77209816A NZ 772098 A NZ772098 A NZ 772098A
- Authority
- NZ
- New Zealand
- Prior art keywords
- dcm
- treatment
- dilated cardiomyopathy
- substituted piperidine
- methylsulfonyl
- Prior art date
Links
- 206010056370 Congestive cardiomyopathy Diseases 0.000 title abstract 4
- 201000010046 Dilated cardiomyopathy Diseases 0.000 title abstract 4
- -1 4-methylsulfonyl-substituted piperidine urea compounds Chemical class 0.000 title 1
- 206010071436 Systolic dysfunction Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- MSCIISHDSZZFEH-UHFFFAOYSA-N piperidine;urea Chemical class NC(O)=N.C1CCNCC1 MSCIISHDSZZFEH-UHFFFAOYSA-N 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000002861 ventricular Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention provides novel 4-methylsulphone-substituted piperidine urea compounds that are useful for the treatment of dilated cardiomyopathy (DCM) and conditions associated with left and/or right ventricular systolic dysfunction or systolic reserve. The synthesis and characterization of the compounds is described, as well as methods for treating DCM and other forms of heart disease.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562106571P | 2015-01-22 | 2015-01-22 | |
| NZ734020A NZ734020B2 (en) | 2016-01-21 | 4-methylsulfonyl-substituted piperidine urea compounds for the treatment of dilated cardiomyopathy (dcm) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NZ772098A true NZ772098A (en) | 2023-10-27 |
| NZ772098B2 NZ772098B2 (en) | 2024-01-30 |
Family
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed |