NZ761611A - Single-chain trail-receptor agonist proteins - Google Patents
Single-chain trail-receptor agonist proteinsInfo
- Publication number
- NZ761611A NZ761611A NZ761611A NZ76161115A NZ761611A NZ 761611 A NZ761611 A NZ 761611A NZ 761611 A NZ761611 A NZ 761611A NZ 76161115 A NZ76161115 A NZ 76161115A NZ 761611 A NZ761611 A NZ 761611A
- Authority
- NZ
- New Zealand
- Prior art keywords
- receptor agonist
- agonist proteins
- trail
- chain trail
- trail receptor
- Prior art date
Links
- 229940123369 TRAIL receptor agonist Drugs 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 101100369992 Homo sapiens TNFSF10 gene Proteins 0.000 abstract 2
- 102000046283 TNF-Related Apoptosis-Inducing Ligand Human genes 0.000 abstract 2
- 108700012411 TNFSF10 Proteins 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 abstract 1
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 abstract 1
- 230000004931 aggregating effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461983152P | 2014-04-23 | 2014-04-23 | |
| NZ725476A NZ725476B2 (en) | 2015-04-23 | Single-chain trail-receptor agonist proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ761611A true NZ761611A (en) | 2023-05-26 |
Family
ID=86613245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ761611A NZ761611A (en) | 2014-04-23 | 2015-04-23 | Single-chain trail-receptor agonist proteins |
Country Status (1)
| Country | Link |
|---|---|
| NZ (1) | NZ761611A (en) |
-
2015
- 2015-04-23 NZ NZ761611A patent/NZ761611A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed |