NZ733080A - Pharmaceutical nanoparticles showing improved mucosal transport - Google Patents
Pharmaceutical nanoparticles showing improved mucosal transportInfo
- Publication number
- NZ733080A NZ733080A NZ733080A NZ73308013A NZ733080A NZ 733080 A NZ733080 A NZ 733080A NZ 733080 A NZ733080 A NZ 733080A NZ 73308013 A NZ73308013 A NZ 73308013A NZ 733080 A NZ733080 A NZ 733080A
- Authority
- NZ
- New Zealand
- Prior art keywords
- particles
- showing improved
- poloxamer
- pharmaceutical
- improved mucosal
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008177 pharmaceutical agent Substances 0.000 abstract 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 1
- 229920002511 Poloxamer 237 Polymers 0.000 abstract 1
- 229920002517 Poloxamer 338 Polymers 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- DMKSVUSAATWOCU-HROMYWEYSA-N loteprednol etabonate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)OCCl)(OC(=O)OCC)[C@@]1(C)C[C@@H]2O DMKSVUSAATWOCU-HROMYWEYSA-N 0.000 abstract 1
- 229960003744 loteprednol etabonate Drugs 0.000 abstract 1
- 210000003097 mucus Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001992 poloxamer 407 Polymers 0.000 abstract 1
- 229940044476 poloxamer 407 Drugs 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
Particles, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles with poloxamer 407, poloxamer 338 or poloxamer 237. The particles may comprise a pharmaceutical agent such as loteprednol etabonate. The pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261642313P | 2012-05-03 | 2012-05-03 | |
| US201261642261P | 2012-05-03 | 2012-05-03 | |
| US201261738949P | 2012-12-18 | 2012-12-18 | |
| US201361784701P | 2013-03-14 | 2013-03-14 | |
| NZ728721A NZ728721A (en) | 2012-05-03 | 2013-05-03 | Pharmaceutical nanoparticles showing improved mucosal transport |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ733080A true NZ733080A (en) | 2017-12-22 |
Family
ID=60669070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ733080A NZ733080A (en) | 2012-05-03 | 2013-05-03 | Pharmaceutical nanoparticles showing improved mucosal transport |
Country Status (1)
| Country | Link |
|---|---|
| NZ (1) | NZ733080A (en) |
-
2013
- 2013-05-03 NZ NZ733080A patent/NZ733080A/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 MAY 2019 BY DENNEMEYER + CO Effective date: 20180509 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 MAY 2020 BY DENNEMEYER + CO. Effective date: 20190419 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 MAY 2021 BY PETRA OLK Effective date: 20200421 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 MAY 2022 BY DENNEMEYER + CO. Effective date: 20210426 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 MAY 2023 BY DENNEMEYER + CO. Effective date: 20220425 |
|
| ASS | Change of ownership |
Owner name: ALCON INC, CH Effective date: 20221019 |
|
| LAPS | Patent lapsed |