NZ602758A - Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one lactic acid salts - Google Patents

Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one lactic acid salts

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Publication number
NZ602758A
NZ602758A NZ602758A NZ60275806A NZ602758A NZ 602758 A NZ602758 A NZ 602758A NZ 602758 A NZ602758 A NZ 602758A NZ 60275806 A NZ60275806 A NZ 60275806A NZ 602758 A NZ602758 A NZ 602758A
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NZ
New Zealand
Prior art keywords
benzimidazol
quinolin
fluoro
crystalline
amino
Prior art date
Application number
NZ602758A
Inventor
Augustus Okhamafe
Joyce Chou
Rampurna Gullapalli
Eric Harwood
David Ryckman
Shuguang Zhu
Xiao Shang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NZ602758A publication Critical patent/NZ602758A/en

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Abstract

Disclosed are crystalline or amorphous forms of a lactic acid salt of 4-amino-5-fluoro-3-[6-(4-methylpiperzin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one (Formula I), and solvates and hydrates thereof. The compound of formula I is a protein kinase inhibitor and is useful in the treatment of cancer.
NZ602758A 2005-05-23 2006-05-23 Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one lactic acid salts NZ602758A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68399905P 2005-05-23 2005-05-23
NZ59197606 2006-05-23

Publications (1)

Publication Number Publication Date
NZ602758A true NZ602758A (en) 2014-01-31

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Application Number Title Priority Date Filing Date
NZ602758A NZ602758A (en) 2005-05-23 2006-05-23 Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one lactic acid salts

Country Status (1)

Country Link
NZ (1) NZ602758A (en)

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Free format text: PATENT RENEWED FOR 6 YEARS UNTIL 23 MAY 2016 BY BALDWINS INTELLECTUAL PROPERTY

Effective date: 20140506

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Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 23 MAY 2017 BY CPA GLOBAL

Effective date: 20160409

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