NZ525368A - Novel aggrecanase molecules - Google Patents
Novel aggrecanase moleculesInfo
- Publication number
- NZ525368A NZ525368A NZ525368A NZ52536801A NZ525368A NZ 525368 A NZ525368 A NZ 525368A NZ 525368 A NZ525368 A NZ 525368A NZ 52536801 A NZ52536801 A NZ 52536801A NZ 525368 A NZ525368 A NZ 525368A
- Authority
- NZ
- New Zealand
- Prior art keywords
- aggrecanase
- antibodies
- enzymes
- inhibitors
- novel aggrecanase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The identification of aggrecanase protein molecules capable of cleaving aggrecanase, the nucleotide sequences which encode aggrecanase enzymes and the processes for the production of aggrecanases are disclosed. The composition comprises the aggrecanase enzymes, the antibodies and methods for developing inhibitors of the aggrecanase. The inhibitors and antibodies may be used in the treatment of conditions characterised by degradation of articular cartilage.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24231700P | 2000-10-20 | 2000-10-20 | |
PCT/US2001/032596 WO2002034895A2 (en) | 2000-10-20 | 2001-10-17 | Novel aggrecanase molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ525368A true NZ525368A (en) | 2006-03-31 |
Family
ID=22914296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ525368A NZ525368A (en) | 2000-10-20 | 2001-10-17 | Novel aggrecanase molecules |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1326967A2 (en) |
JP (2) | JP2004512043A (en) |
AU (1) | AU2002245758A1 (en) |
BR (1) | BR0114719A (en) |
CA (1) | CA2426463A1 (en) |
CZ (1) | CZ2003996A3 (en) |
MX (1) | MXPA03003425A (en) |
NO (1) | NO20031649L (en) |
NZ (1) | NZ525368A (en) |
PL (1) | PL362008A1 (en) |
SK (1) | SK4632003A3 (en) |
WO (1) | WO2002034895A2 (en) |
ZA (1) | ZA200303865B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018277343A1 (en) | 2017-06-02 | 2020-01-02 | Ablynx N.V. | Adamts binding immunoglobulins |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6391610B1 (en) * | 1999-08-06 | 2002-05-21 | The Cleveland Clinic Foundation | Nucleic acids encoding zinc metalloproteases |
AU7717800A (en) * | 1999-09-27 | 2001-04-30 | Curagen Corporation | Novel polynucleotides encoding proteins containing thrombospondin type 1 repeats |
-
2001
- 2001-10-17 EP EP01988767A patent/EP1326967A2/en not_active Ceased
- 2001-10-17 PL PL36200801A patent/PL362008A1/en unknown
- 2001-10-17 JP JP2002537866A patent/JP2004512043A/en not_active Withdrawn
- 2001-10-17 WO PCT/US2001/032596 patent/WO2002034895A2/en active Application Filing
- 2001-10-17 AU AU2002245758A patent/AU2002245758A1/en not_active Abandoned
- 2001-10-17 BR BR0114719-6A patent/BR0114719A/en not_active IP Right Cessation
- 2001-10-17 NZ NZ525368A patent/NZ525368A/en unknown
- 2001-10-17 SK SK463-2003A patent/SK4632003A3/en not_active Application Discontinuation
- 2001-10-17 CA CA002426463A patent/CA2426463A1/en not_active Abandoned
- 2001-10-17 MX MXPA03003425A patent/MXPA03003425A/en active IP Right Grant
- 2001-10-17 CZ CZ2003996A patent/CZ2003996A3/en unknown
-
2003
- 2003-04-10 NO NO20031649A patent/NO20031649L/en not_active Application Discontinuation
- 2003-05-19 ZA ZA200303865A patent/ZA200303865B/en unknown
-
2008
- 2008-05-07 JP JP2008121344A patent/JP2008301813A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CZ2003996A3 (en) | 2004-04-14 |
MXPA03003425A (en) | 2004-05-04 |
BR0114719A (en) | 2004-01-27 |
CA2426463A1 (en) | 2002-05-02 |
WO2002034895A3 (en) | 2002-10-10 |
PL362008A1 (en) | 2004-10-18 |
SK4632003A3 (en) | 2004-05-04 |
JP2008301813A (en) | 2008-12-18 |
WO2002034895A2 (en) | 2002-05-02 |
AU2002245758A1 (en) | 2002-05-06 |
NO20031649L (en) | 2003-06-11 |
NO20031649D0 (en) | 2003-04-10 |
ZA200303865B (en) | 2004-08-19 |
EP1326967A2 (en) | 2003-07-16 |
JP2004512043A (en) | 2004-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RENW | Renewal (renewal fees accepted) | ||
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |