NZ502473A - The preparation of encapsulated pancreatic beta islet cells treated with nicotinamide from piglets able to produce porcine insulin - Google Patents
The preparation of encapsulated pancreatic beta islet cells treated with nicotinamide from piglets able to produce porcine insulinInfo
- Publication number
- NZ502473A NZ502473A NZ50247300A NZ50247300A NZ502473A NZ 502473 A NZ502473 A NZ 502473A NZ 50247300 A NZ50247300 A NZ 50247300A NZ 50247300 A NZ50247300 A NZ 50247300A NZ 502473 A NZ502473 A NZ 502473A
- Authority
- NZ
- New Zealand
- Prior art keywords
- piglets
- islet cells
- nicotinamide
- preparation
- pancreas
- Prior art date
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Xenotransplantable porcine islet preparations capable of producing porcine insulin in a suitable mammal are prepared from the pancreas of piglets at or near full term gestation. The method comprises harvesting the pancreas of piglets that are from -7 to +10 days full term gestation. A culture of the pancreatic b islet cells is prepared from the harvested pancreas in a supportive mammalian albumin, free of non-human microbiological agents. Simultaneously or after the preparation of the culture pancreatic b islet cells are extracted from the culture of the harvested pancreas. The extraction is performed using a collagenase selected from purified human collagenase or purified porcine collagenase. At some stage of the method the islets are treated with nicotinamide. Further more after extraction the islets can be encapsulated with a biocompatible xenotransplantable material that is glucose and insulin porous.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ50247300A NZ502473A (en) | 2000-01-20 | 2000-01-20 | The preparation of encapsulated pancreatic beta islet cells treated with nicotinamide from piglets able to produce porcine insulin |
DK01942558T DK1248640T3 (en) | 2000-01-20 | 2001-01-19 | Xenotransplantation of pig islets and their production |
EP01942558A EP1248640B1 (en) | 2000-01-20 | 2001-01-19 | Preparation and xenotransplantation of porcine islets |
AU28930/01A AU780366B2 (en) | 2000-01-20 | 2001-01-19 | Preparation and xenotransplantation of porcine islets |
US09/857,325 US7122177B2 (en) | 2000-01-20 | 2001-01-19 | Preparation and xenotransplantation of porcine islets |
ES01942558T ES2272482T3 (en) | 2000-01-20 | 2001-01-19 | PREPARATION AND XENOTRANSPLANT OF SWINE ISLOTS. |
AT01942558T ATE341335T1 (en) | 2000-01-20 | 2001-01-19 | PREPARATION AND XENOTRANSPLANTATION OF ISLANDS FROM PIGS |
PCT/NZ2001/000006 WO2001052871A1 (en) | 2000-01-20 | 2001-01-19 | Preparation and xenotransplantation of porcine islets |
DE60123574T DE60123574T2 (en) | 2000-01-20 | 2001-01-19 | PREPARATION AND XENOTRANSPLANTATION OF PIG ISLANDS |
US10/443,344 US7323323B2 (en) | 2000-01-20 | 2003-05-22 | Preparation and xenotransplantation of porcine islets |
US11/932,538 US8142769B2 (en) | 2000-01-20 | 2007-10-31 | Preparation and xenotransplantation of porcine islets |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ50247300A NZ502473A (en) | 2000-01-20 | 2000-01-20 | The preparation of encapsulated pancreatic beta islet cells treated with nicotinamide from piglets able to produce porcine insulin |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ502473A true NZ502473A (en) | 2002-09-27 |
Family
ID=19927718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ50247300A NZ502473A (en) | 2000-01-20 | 2000-01-20 | The preparation of encapsulated pancreatic beta islet cells treated with nicotinamide from piglets able to produce porcine insulin |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ502473A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7122177B2 (en) | 2000-01-20 | 2006-10-17 | Diabcell Pty Ltd. | Preparation and xenotransplantation of porcine islets |
-
2000
- 2000-01-20 NZ NZ50247300A patent/NZ502473A/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7122177B2 (en) | 2000-01-20 | 2006-10-17 | Diabcell Pty Ltd. | Preparation and xenotransplantation of porcine islets |
US7323323B2 (en) | 2000-01-20 | 2008-01-29 | Diabell Pty Ltd. | Preparation and xenotransplantation of porcine islets |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
ASS | Change of ownership |
Owner name: DIABCELL PTY LIMITED, AU Free format text: OLD OWNER(S): DIATRANZ LIMITED |
|
RENW | Renewal (renewal fees accepted) | ||
RENW | Renewal (renewal fees accepted) | ||
RENW | Renewal (renewal fees accepted) | ||
ASS | Change of ownership |
Owner name: DIATRANZ OTSUKA LIMITED, NZ Free format text: OLD OWNER(S): DIABCELL PTY LTD |
|
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 7 YEARS UNTIL 31 JAN 2021 BY AJ PARK Effective date: 20140113 |
|
EXPY | Patent expired |