NZ334568A - Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof - Google Patents
Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereofInfo
- Publication number
- NZ334568A NZ334568A NZ334568A NZ33456897A NZ334568A NZ 334568 A NZ334568 A NZ 334568A NZ 334568 A NZ334568 A NZ 334568A NZ 33456897 A NZ33456897 A NZ 33456897A NZ 334568 A NZ334568 A NZ 334568A
- Authority
- NZ
- New Zealand
- Prior art keywords
- amino acid
- nucleic acid
- helicobacter pylori
- vaccine compositions
- acid sequences
- Prior art date
Links
- 125000003275 alpha amino acid group Chemical group 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 241000590002 Helicobacter pylori Species 0.000 title 1
- 229940037467 helicobacter pylori Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 206010019375 Helicobacter infections Diseases 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
An isolated nucleic acid comprising a nucleotide sequence encoding and H.pylori polypeptide comprising an amino acid sequence that has at least 60% homology with an amino acid sequence selected from the groups: Sequences 76, 98, 121, 83, 89, 118, 108, 110, 80, 112, 128, 91, 92, 101, 103, 125, 127, 129, 131, 74, 115, 87, 116, 84, 144, 90, 130, 78, 79, 81 and 94 as disclosed in the specification. Further claimed is a probe, recombinant expression vector, cell containing the vector, and method for producing an H.pylori polypeptide by culturing the cell containing the vector. Also claimed is a vaccine and use of the vaccine to treat Helicobacter pylori infection.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73915096A | 1996-10-28 | 1996-10-28 | |
| US75973996A | 1996-12-06 | 1996-12-06 | |
| US89192897A | 1997-07-14 | 1997-07-14 | |
| PCT/US1997/019575 WO1998018323A1 (en) | 1996-10-28 | 1997-10-28 | Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ334568A true NZ334568A (en) | 2000-04-28 |
Family
ID=27419246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ334568A NZ334568A (en) | 1996-10-28 | 1997-10-28 | Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0973394A4 (en) |
| JP (1) | JP2001504329A (en) |
| KR (1) | KR20000052831A (en) |
| CN (1) | CN1235513A (en) |
| AR (1) | AR009600A1 (en) |
| AU (1) | AU734052B2 (en) |
| BR (1) | BR9712587A (en) |
| CA (1) | CA2265523A1 (en) |
| EE (1) | EE9900176A (en) |
| ID (1) | ID22065A (en) |
| IL (1) | IL129397A0 (en) |
| IS (1) | IS5005A (en) |
| NO (1) | NO991995L (en) |
| NZ (1) | NZ334568A (en) |
| PL (1) | PL333169A1 (en) |
| SA (1) | SA98180918A (en) |
| SK (1) | SK34699A3 (en) |
| TR (1) | TR199900940T2 (en) |
| WO (1) | WO1998018323A1 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6406703B1 (en) | 1993-07-27 | 2002-06-18 | Csl Limited | Treatment of H. pylori associated gastroduodenal disease |
| CA2154063C (en) * | 1993-07-27 | 2006-11-21 | Christopher Vincent Doidge | Treatment of h. pylori associated gastroduodenal disease |
| DE19730425A1 (en) | 1997-07-16 | 1999-01-21 | Henkel Teroson Gmbh | Heat-curing laundry-resistant shell sealant |
| AU4793499A (en) * | 1998-07-27 | 2000-02-21 | Aventis Pasteur Limited | (chlamydia) antigens and corresponding dna fragments and uses thereof |
| SE9901548D0 (en) * | 1999-04-29 | 1999-04-29 | Astra Ab | Helicobacter pylori antigens |
| GB9914945D0 (en) * | 1999-06-25 | 1999-08-25 | Smithkline Beecham Biolog | Novel compounds |
| AUPQ347199A0 (en) * | 1999-10-15 | 1999-11-11 | Csl Limited | Novel polypeptide fragments |
| CN101532001A (en) * | 2000-03-08 | 2009-09-16 | 诺维信公司 | Variants with altered properties |
| GB0010371D0 (en) * | 2000-04-29 | 2000-06-14 | Astrazeneca Ab | Helicobacter pylori antigens |
| GB0010370D0 (en) * | 2000-04-29 | 2000-06-14 | Astrazeneca Ab | Helicobacter pylori antigens |
| EP2695938B1 (en) | 2011-03-17 | 2016-11-30 | National UniversityCorporation Mie University | Antibody production method |
| KR20180096643A (en) * | 2015-12-14 | 2018-08-29 | 테크니쉐 유니베르시테트 뮌헨 | Helicobacter pylori vaccine |
| CN115724922B (en) * | 2022-07-19 | 2023-08-22 | 四川大学华西医院 | Helicobacter pylori vaccine recombinant protein antigen TonB, preparation method and application thereof |
| CN115581201A (en) * | 2022-08-26 | 2023-01-10 | 云南省农业科学院花卉研究所 | Diploid rose F induced by stem segment as explant 1 -61 plant regeneration method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9300139L (en) * | 1993-01-19 | 1994-07-20 | Medicarb Ab | Preparation of a new drug |
-
1997
- 1997-10-28 NZ NZ334568A patent/NZ334568A/en unknown
- 1997-10-28 JP JP52071098A patent/JP2001504329A/en active Pending
- 1997-10-28 CN CN97199233A patent/CN1235513A/en active Pending
- 1997-10-28 AR ARP970105002A patent/AR009600A1/en not_active Application Discontinuation
- 1997-10-28 IL IL12939797A patent/IL129397A0/en unknown
- 1997-10-28 TR TR1999/00940T patent/TR199900940T2/en unknown
- 1997-10-28 ID IDW990160A patent/ID22065A/en unknown
- 1997-10-28 EE EEP199900176A patent/EE9900176A/en unknown
- 1997-10-28 AU AU50933/98A patent/AU734052B2/en not_active Ceased
- 1997-10-28 BR BR9712587-3A patent/BR9712587A/en not_active IP Right Cessation
- 1997-10-28 SK SK346-99A patent/SK34699A3/en unknown
- 1997-10-28 KR KR1019990703660A patent/KR20000052831A/en not_active Application Discontinuation
- 1997-10-28 EP EP97913847A patent/EP0973394A4/en not_active Withdrawn
- 1997-10-28 CA CA002265523A patent/CA2265523A1/en not_active Abandoned
- 1997-10-28 WO PCT/US1997/019575 patent/WO1998018323A1/en not_active Application Discontinuation
- 1997-10-28 PL PL97333169A patent/PL333169A1/en unknown
-
1998
- 1998-02-28 SA SA98180918A patent/SA98180918A/en unknown
-
1999
- 1999-03-18 IS IS5005A patent/IS5005A/en unknown
- 1999-04-27 NO NO991995A patent/NO991995L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EE9900176A (en) | 1999-12-15 |
| KR20000052831A (en) | 2000-08-25 |
| SK34699A3 (en) | 2000-04-10 |
| ID22065A (en) | 1999-08-26 |
| IS5005A (en) | 1999-03-18 |
| SA98180918A (en) | 2005-12-03 |
| JP2001504329A (en) | 2001-04-03 |
| BR9712587A (en) | 1999-10-26 |
| TR199900940T2 (en) | 1999-09-21 |
| AU734052B2 (en) | 2001-05-31 |
| CN1235513A (en) | 1999-11-17 |
| CA2265523A1 (en) | 1998-05-07 |
| NO991995L (en) | 1999-06-28 |
| AR009600A1 (en) | 2000-04-26 |
| IL129397A0 (en) | 2000-02-17 |
| NO991995D0 (en) | 1999-04-27 |
| EP0973394A4 (en) | 2005-03-30 |
| AU5093398A (en) | 1998-05-22 |
| WO1998018323A1 (en) | 1998-05-07 |
| PL333169A1 (en) | 1999-11-22 |
| EP0973394A1 (en) | 2000-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) | ||
| S38A | Application for proceedings under section 38 (amendment of specification with leave of commissioner) |
Free format text: AMENDMENT BY WAY OF DISCLAIMER BY DELETION OF CLAIMS 7 TO 9, 18 TO 25, 47 TO 53, 75, 79, 81 TO 82, AND BY WAY OF DELETION OF A CLAUSE |
|
| S38C | Proceedings under section 38 (amendment of specification with leave of commissioner): specification amended |