NZ202832A - Whey food product obtained from udder treated with antigen material - Google Patents
Whey food product obtained from udder treated with antigen materialInfo
- Publication number
- NZ202832A NZ202832A NZ20283282A NZ20283282A NZ202832A NZ 202832 A NZ202832 A NZ 202832A NZ 20283282 A NZ20283282 A NZ 20283282A NZ 20283282 A NZ20283282 A NZ 20283282A NZ 202832 A NZ202832 A NZ 202832A
- Authority
- NZ
- New Zealand
- Prior art keywords
- milk
- whey
- colostrum
- food product
- food
- Prior art date
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dairy Products (AREA)
Description
New Zealand Paient Spedficaiion for Paient Number £02832
2 02832
Priority Date(s):
Complete Specification Filed:
Clasis: . /9. ... 9rjJ.OO.
Publication Date: ... 2.4. JAW .law P.O. Journal, No: ./?. 7??!
NEW ZEALAND PATENTS ACT, 1953
No.:
Date:
COMPLETE SPECIFICATION WHEY PRODUCT AND METHOD FOR OBTAINING SAME
X/ We, IMPRO PRODUCTS, INC., a company incorporated in the State of Minnesota, U.S.A., of 3 Allamakee Street, Waukon, State of Iowa, U.S.A.
hereby declare the invention for which2*! / we pray that a patent may be granted to n53</us, and the method by which it is to be performed, to be particularly described in and by the following statement: - ;- 1 - ;(followed by page la) ;202832 ;-i? ;The present invention relates to the production of a novel food product. In particular, it relates to whey obtained from the colostrum and milk of ungulates. ;5 The process of the invention involves the pre- ;partum introduction of specific antigen-like material into the udder of an ungulate to enhance to an economic level the food factQr in whey and to extract, from colostrum and milk from ungulates so treated the ;10 whey portion possessing the new food product by a process which entails passage of such whey through a sterilizing filter without denaturing the molecules contained therein ;A variety of the antigen-like materials can be used to activate the udder - such as, but not limited 15 to, pollen, bacteria, virus, mold, allergens, blood from sick animals and sperm. ;More specifically, the food product of the invention is characterized by an active fraction having moiecular weight of less than 1200. 20 According to the present invention, there is provided the method of producing a food product, characterized by: introducing " into the udder of an ungulate a specific antigen-like material selected from the group consisting of pollen, bacteria, 25 virus, mold, allergens, blood from sick animals, sperm and toxins; removing secretory fluid from the udder of the ungulate thus treated; extracting whey from said fluid; and separating from said whey large molecules ;along with contaminants such as bacteria, to produce a purified whey containing a food factor having a molecular weight on the order of 1200 or less. ;In one method of practicing our invention, the 5 antigen-like material is introduced into the udder of an ungulate in an asceptic manner two or three times, at weekly intervals during the last month of gestation. ;This can be accomplished by using a sterile syringe and hypodermic needle, and injecting the material into the 10 side of the udder; or the material can be introduced through the teat canal using a sterile syringe and a blunt plastic needle inserted through the orifice of the teat into the cistern. ;At parturition, the ungulate is milked twice 15 daily during the .colostrum flow period, and the colostrum is collected in containers and refrigerated, allowing the fat to rise. The fat is then skimmed off. The skimmed colostrum is then frozen to allow storage thereof and to effect a separation of the suspended solids therein. 20 Milk produced following the colostrum is collected and has the fat removed by centrifugation, as by a cream separator. The resulting skim milk is most conveniently placed in five or ten gallon cans and frozen to effect a separation of the milk curd solids. These 25 solids precipitate better the longer the milk is frozen. The usual freeze period can be sixty days or more. The frozen skim milk can be saved until a suitable size batch is accumulated, usually about fifty to one-hundred (50-100) gallons. ;30 The skimmed colostrum is then removed from the freezer and allowed to thaw gradually at room temperature. The clear liquid is then siphoned off from the colostrum and put in a refrigerated first vat. The remaining slurry is put into a second vat. ;35 Next, the skim milk from the batch is removed from the freezer and allowed to thaw gradually, usually overnight at room temperature. The clear liquid is ;2028|/ ;'* I
siphoned off and added to the clear liquid in the first vat containing the clear liquid from the colostrum.
The remaining skim milk slurry is then added to the slurry from the colostrum in the second vat. The 5 temperature of the slurry from the colostrum and milk in the second vat is then raised to about 1Q3°F. to 110°?.,
which temperature has been found to be best suited for coagulation of the milk curd solids by acid.
Hydrochloric acid (37% USP), diluted 1:10 1Q with distilled water, is slowly added to the second vat while the combined slurries are stirred. The acidity of the batch thus formed is then monitored and enough acid added to bring the contents to the desired acidity,
which is approximately 4.5 pH. The milk curds (solids) 15 are removed by conventional filtering means so that only the whey portion remains. The whey thus separated from the slurry is then transferred to the refrigerated first vat containing the clear mixture of liquid previously siphoned off from the colostrum and milk. 2Q A preservative such as phenol, parabehs, etc.,
is next added to the refrigerated whey in the first vat.
It will be understood, of course, that no more than the maximum allowable quantities of such preservatives are used.
The whey thus produced is further processed through an ultrafiltration unit. Ultrafiltration units outfitted with filtration media of 0.2 micron and smaller have been successfully employed.
Ultrafiltration has been used in the industry 30 for the concentration of protein and lactose in whey, a process in which the filtrate (permeate) is discarded. Our process distinguishes from that previously used in the industry by being the reverse thereof. We use ultrafiltration to remove the protein, globulin, large 35 molecules and contaminants from the whey permeate, a portion of which consists of the desired specific food factors having a molecular weight of 1200, while the remainder contains other
-4- 2 023
present in milk and colostrum as it comes from the cow.
Thus, in our process, the filtrate (permeate) is saved and the concentrate or retinate is discarded.
At this point, the filtrate (permeate) con-5 taining the desired food factors constituting our new product is further processed by asceptically bott1Eirt§ for direct consumption or by freeze-drying to prdduce a product in powder form. Ideally, heat substantially abo\re that of the normal body temperature of an ungulate 10 should not be applied to the product for concentration, and the product should not be allowed to reach pasteuriz-ing temperature.
In addition to the specific food factor in the colostrum and milk of the ungulate treated in the manner 15 aforementioned, our new food product also contains numerable factors normally present in colostrum and^ milk, some of which are viable and all of which are benificial for animals. At the present time, we do not know the actual identity of our new food product, but its value 20 has been proven by extensive and conclusive tests at the Lobund Institute of the University of Notre Dame, U.S.A.
A preliminary report on these tests was made at a symposium entitled "Gnotobiology for the 80ls: Technical and Application" ^published by "The Association 25 for Gnotobiotics" at their 18th annual meeting held
July 10-13, 1980, at the Whitehall Hotel, Houston, Texas, U.S.A. That symposium was hosted by the University of Texas System Cancer Center M.Do Anderson Hospital■ "& Tumor Institute, Texas Medical Center, Houston, Texas, U.S.A., 30 and the program lists the following abstract:
. Anticaries Effect on Colostrum Whey from
Cows Treated Prepartum with a Streptococcus mutons Bacteria via Intramammary Infusxon.
Morris Wagner, University of Notre Dame, . 35 Notre Dame, Indiana, U.S.A.
However, it has been determined that the term
"specific unknown food factor", as used herein, designates a food factor having a molecular weight of less'than 1200.
2 028
To achieve the desired economic level of this unknown food factor in the colostrum and milk of an ungulate/
it is essential to introduce prepartum into the udder of the ungulate, a specific antigen-like material.
Such antigen-like material can comprise (for instance) pollen, bacteria, virus, mold, allergens, blood'Jfrom sick animals, sperm and toxins.
The presence and amount of this specific unknown food factor in our product has been established 1Q by the use of mouse protection studies at the WARF Institute of the University of Wisconsin, Madison, Wisconsin, U.S.A. The method of measurement - namely, "mouse unit" - is also that which has been established by WARF.
A mouse unit is the minimum amount of our food product obtained from a specific batch, required to protect for a predetermined time a mouse that has been challenged with a lethal dose of the same antigenlike material introduced prepartum into the udder of 2Q the donor ungulate used in the production of said batch. The accepted definition of a mouse unit is contained in the book entitled "Chemistry and Physiology of the Vitamins" by H.R. Rosenberg, SC.D, revised reprint 1945; Interscience Publishers, Inc., New York, New York 25 U.S.A. Page 24. j
We have established that if a mouse unit is lcc of our food product:
(A) lcc of our product reduced to a powder by freeze drying constitutes a mouse unit; and
(B) lcc of our product with all molecules over
1200 M.W. removed also constitutes a mouse unit.
In a more general sense, this invention can be said to reside in introducing prepartum into the udder of 35 an ungulate a specific antigen-like material, collecting the colostrum and milk after parturition, processing it by extracting the whey therefrom, and filtering the whey through a filter having a pore size preferably not greater
2 02
than 0.2 microns. The final filtrate contains the desired unknown food factor, along with all factors in whey processed from colostrum and milk as it comes from the treated ungulate.
In addition to the unknown food factor, enhanced to an economic level by the prepartum introduction of a specific antigen-like material into the udder of an ungulate, our new food product contains other beneficial factors on the order of B Lysin, Conglutinin, Interferon, 10 Lactoferrin, Lactoperoxidase, B Lymphocytes,
T Lymphocytes, Lysozyme, Macrophages, Polypeptides, Properdin and Thiocyanate that are in the colostrum and milk as it comes from the ungulate and which may be extracted along with the desired unknown specific food 15 factor.
Another satisfactory way of processing the colostrum and milk to extract therefrom the whey containing the specific food factor is to hold the same vuider refrigeration until the desired batch has been 20 collected, and then passing the colostrum and milk,
while at a temperature approximately that of the udder of an ungulate, through a filter that passes only food factors of the molecular weight of the class desired.
Again, experience has shown a filter not greater than 25 0.2 microns to be satisfactory.
In this manner, the food value of the factors is maintained while eliminating contaminants that may be in the milk and colostrum.
In^either process.described above, the antigen-30 like material can comprise a solution of lOcc per teat of the ungulate with each cc having in solution a count of 750 million of the material. This has been found to be most effective when the antigen-like material is comprised of bacteria or virus, but when it comprises the blood of 35 a sick animal, only 5cc of the blood is injected into each teat.
From the foregoing description, it will be
Claims (6)
1. A method of producing a food product, characterized by: introducing into the udder of an ungulate a specific antigen-like material selected from the group consisting of pollen, bacteria, virus, mold, allergens, blood from sick animals, sperm and toxins; removing secretory fluid from the udder of the ungulate thus treated; extracting whey from said fluid; and passing said whey through a filter having a pore size of 0.2 microns, to produce a purified whey containing a food factor having a molecular weight of 1200 or less.
2. A method of producing a food product according to claim 1, wherein said secretory fluid comprises'colostrum and milk. .
3. A method of producing a food product according to claim 2, including separating the fat from the colostrum and milk obtained from said udder; thereafter freezing the colostrum and milk to effect precipitation of the milk curd solids therein; gradually thawing said frozen colostrum and milk; siphoning off clear whey from the thawed colostrum and milk; heating the remaining slurry portion of the colostrum and milk to a temperature of approximately 103° to 110°F.; mixing a dilute acid with said remaining slurry portion to produce a pH that causes coagulation of the milk curd solids therein; separating said solids from the slurry so that only whey remains; blending such remaining whey with the whey portion previously siphoned off; and filtering said blend through a filter as claimed in claim 1, to produce a permeate comprising said purified whey containing a food factor having a molecular weight of 1200 or less.
4 . A method for preparing a food product according to claim 1, substantially as hereinbefore specifically described.
5. A food product whenever obtained by the process of any one of the preceding claims.
6. A food product obtained by the.; method of any one of claims 1 to 4 wherein the secretory fluid comprises colostrum and milk and said product comprises colostrum whey and milk whey containing a food ^^jTr^j^ctor having a molecular weight of 1200 or less. By authorised Agenes o •' ,-x ,A . .*•./ f:ifrnr» \ A. J. PARK & SON. f,r CD
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ20283282A NZ202832A (en) | 1982-12-17 | 1982-12-17 | Whey food product obtained from udder treated with antigen material |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ20283282A NZ202832A (en) | 1982-12-17 | 1982-12-17 | Whey food product obtained from udder treated with antigen material |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ202832A true NZ202832A (en) | 1986-01-24 |
Family
ID=19920206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ20283282A NZ202832A (en) | 1982-12-17 | 1982-12-17 | Whey food product obtained from udder treated with antigen material |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ202832A (en) |
-
1982
- 1982-12-17 NZ NZ20283282A patent/NZ202832A/en unknown
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