NZ187376A - N-cyano-n-(2-(4-methyl-5-imidazolyl)methylthio)ethyl)-n-alkynyl guanidines intermediates pharmaceutical compositions - Google Patents

N-cyano-n-(2-(4-methyl-5-imidazolyl)methylthio)ethyl)-n-alkynyl guanidines intermediates pharmaceutical compositions

Info

Publication number: NZ187376A
Authority: NZ; New Zealand
Prior art keywords: guanidines; methylthio; imidazolyl; intermediates; alkynyl
Prior art date: 1977-06-03

Application number

NZ187376A

Inventor

R R Crenshaw

G M Luke

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-06-03

Filing date

1978-05-25

Publication date

1981-05-29

1977-11-07 Priority claimed from US05/848,959 external-priority patent/US4112234A/en

1978-05-25 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1981-05-29 Publication of NZ187376A publication Critical patent/NZ187376A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NZ187376A 1977-06-03 1978-05-25 N-cyano-n-(2-(4-methyl-5-imidazolyl)methylthio)ethyl)-n-alkynyl guanidines intermediates pharmaceutical compositions NZ187376A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US80300977A	1977-06-03	1977-06-03
US82679677A	1977-08-22	1977-08-22
US05/848,959 US4112234A (en)	1977-08-22	1977-11-07	Imidazolylmethylthioethyl alkynyl guanidines

Publications (1)

Publication Number	Publication Date
NZ187376A true NZ187376A (en)	1981-05-29

Family

ID=27419995

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ187376A NZ187376A (en)	1977-06-03	1978-05-25	N-cyano-n-(2-(4-methyl-5-imidazolyl)methylthio)ethyl)-n-alkynyl guanidines intermediates pharmaceutical compositions

Country Status (26)

Country	Link
JP (1)	JPS543067A (en)
AR (2)	AR222797A1 (en)
CA (1)	CA1110251A (en)
CH (2)	CH641167A5 (en)
CY (3)	CY1230A (en)
DD (1)	DD140038A5 (en)
DE (1)	DE2824066A1 (en)
DK (1)	DK243178A (en)
ES (3)	ES470474A1 (en)
FI (1)	FI69069C (en)
FR (2)	FR2401143A1 (en)
GB (3)	GB1598630A (en)
GR (1)	GR73860B (en)
HK (3)	HK38184A (en)
HU (1)	HU186766B (en)
IE (1)	IE47543B1 (en)
IL (1)	IL54819A (en)
KE (1)	KE3373A (en)
LU (1)	LU79725A1 (en)
MY (3)	MY8500451A (en)
NL (1)	NL7805935A (en)
NO (3)	NO152214C (en)
NZ (1)	NZ187376A (en)
SE (3)	SE443784B (en)
SG (1)	SG8584G (en)
YU (4)	YU129778A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS568352A (en) *	1979-07-03	1981-01-28	Shionogi & Co Ltd	Aminoalkylvenzene derivative
US4339439A (en) *	1981-01-19	1982-07-13	Bristol-Myers Company	Pharmaceutical methods and compositions
JPS57134318A (en) *	1981-02-12	1982-08-19	Nissan Motor Co Ltd	Air mixing construction of air conditioner
JPS5848516U (en) *	1981-09-30	1983-04-01	日産車体株式会社	Vehicle air conditioner
JPS6018010U (en) *	1983-07-18	1985-02-07	日産自動車株式会社	Temperature adjustment mechanism of vehicle air conditioner
JPS60113211U (en) *	1984-01-06	1985-07-31	松下電器産業株式会社	Automotive air conditioner
ES2007948A6 (en) *	1988-07-06	1989-07-01	Vinas Lab	Propargylguanidine derivatives and process for the preparation thereof.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1338169A (en) *	1971-03-09	1973-11-21	Smith Kline French Lab	Ureas thioureas and guanidines
US4024271A (en) *	1971-03-09	1977-05-17	Smith Kline & French Laboratories Limited	Pharmacologically active guanidine compounds
GB1397436A (en) *	1972-09-05	1975-06-11	Smith Kline French Lab	Heterocyclic n-cyanoguinidines
GB1533380A (en) *	1974-09-02	1978-11-22	Smith Kline French Lab	Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) *	1974-09-02	1978-11-08	Smith Kline French Lab	Process for the production of cyanoguanidine derivatives
GB1531221A (en) *	1974-09-02	1978-11-08	Smith Kline French Lab	Process for preparing guanidine derivatives

1978
- 1978-05-25 NZ NZ187376A patent/NZ187376A/en unknown
- 1978-05-25 CA CA304,045A patent/CA1110251A/en not_active Expired
- 1978-05-26 GB GB18923/80A patent/GB1598630A/en not_active Expired
- 1978-05-26 CY CY1230A patent/CY1230A/en unknown
- 1978-05-26 CY CY1231A patent/CY1231A/en unknown
- 1978-05-26 GB GB27637/79A patent/GB1598629A/en not_active Expired
- 1978-05-26 CY CY1229A patent/CY1229A/en unknown
- 1978-05-26 GB GB23611/78A patent/GB1598628A/en not_active Expired
- 1978-05-29 GR GR56374A patent/GR73860B/el unknown
- 1978-05-29 LU LU79725A patent/LU79725A1/en unknown
- 1978-05-31 IL IL54819A patent/IL54819A/en unknown
- 1978-05-31 YU YU01297/78A patent/YU129778A/en unknown
- 1978-05-31 AR AR272401A patent/AR222797A1/en active
- 1978-05-31 FI FI781737A patent/FI69069C/en not_active IP Right Cessation
- 1978-05-31 DK DK243178A patent/DK243178A/en not_active Application Discontinuation
- 1978-05-31 NL NL7805935A patent/NL7805935A/en not_active Application Discontinuation
- 1978-06-01 DE DE19782824066 patent/DE2824066A1/en not_active Withdrawn
- 1978-06-02 CH CH609278A patent/CH641167A5/en not_active IP Right Cessation
- 1978-06-02 ES ES470474A patent/ES470474A1/en not_active Expired
- 1978-06-02 SE SE7806525A patent/SE443784B/en unknown
- 1978-06-02 JP JP6590078A patent/JPS543067A/en active Granted
- 1978-06-02 IE IE1112/78A patent/IE47543B1/en unknown
- 1978-06-02 FR FR7816601A patent/FR2401143A1/en active Granted
- 1978-06-02 NO NO781928A patent/NO152214C/en unknown
- 1978-06-02 HU HU811135A patent/HU186766B/en unknown
- 1978-06-05 DD DD78205794A patent/DD140038A5/en unknown
1979
- 1979-03-01 ES ES478202A patent/ES478202A1/en not_active Expired
- 1979-03-01 ES ES478203A patent/ES478203A1/en not_active Expired
- 1979-03-05 YU YU530/79A patent/YU41620B/en unknown
- 1979-05-16 NO NO791637A patent/NO791637L/en unknown
- 1979-10-26 AR AR278645A patent/AR222503A1/en active
- 1979-11-23 FR FR7928943A patent/FR2436138A1/en active Granted
1982
- 1982-09-27 YU YU2154/82A patent/YU40624B/en unknown
- 1982-09-27 YU YU2155/82A patent/YU40625B/en unknown
1983
- 1983-09-12 NO NO833255A patent/NO151824C/en unknown
- 1983-10-07 CH CH549283A patent/CH644591A5/en not_active IP Right Cessation
1984
- 1984-01-30 SG SG85/84A patent/SG8584G/en unknown
- 1984-02-10 KE KE3373A patent/KE3373A/en unknown
- 1984-03-16 SE SE8401492A patent/SE8401492D0/en not_active Application Discontinuation
- 1984-03-16 SE SE8401491A patent/SE8401491L/en not_active Application Discontinuation
- 1984-05-03 HK HK381/84A patent/HK38184A/en unknown
- 1984-05-03 HK HK380/84A patent/HK38084A/en unknown
- 1984-05-03 HK HK382/84A patent/HK38284A/en unknown
1985
- 1985-12-30 MY MY451/85A patent/MY8500451A/en unknown
- 1985-12-30 MY MY452/85A patent/MY8500452A/en unknown
- 1985-12-30 MY MY453/85A patent/MY8500453A/en unknown

Also Published As

Publication number	Publication date
NO781928L (en)	1978-12-05
FI69069B (en)	1985-08-30
IL54819A0 (en)	1978-07-31
MY8500453A (en)	1985-12-31
FR2401143B1 (en)	1981-12-11
NO151824C (en)	1985-06-12
GB1598629A (en)	1981-09-23
FI69069C (en)	1985-12-10
KE3373A (en)	1984-03-23
CA1110251A (en)	1981-10-06
CH641167A5 (en)	1984-02-15
SE7806525L (en)	1978-12-04
ES478202A1 (en)	1979-06-01
DK243178A (en)	1978-12-04
YU215482A (en)	1983-02-28
NL7805935A (en)	1978-12-05
NO151824B (en)	1985-03-04
HK38284A (en)	1984-05-11
IE781112L (en)	1978-12-03
FI781737A (en)	1978-12-04
SE8401491D0 (en)	1984-03-16
HK38184A (en)	1984-05-11
SE8401492L (en)	1984-03-16
ES470474A1 (en)	1979-09-01
JPS543067A (en)	1979-01-11
ES478203A1 (en)	1979-06-01
SG8584G (en)	1985-02-08
LU79725A1 (en)	1979-02-02
NO152214C (en)	1985-08-28
SE8401492D0 (en)	1984-03-16
HU186766B (en)	1985-09-30
NO152214B (en)	1985-05-13
AR222503A1 (en)	1981-05-29
NO833255L (en)	1978-12-05
CH644591A5 (en)	1984-08-15
YU41620B (en)	1987-12-31
YU53079A (en)	1983-09-30
YU40624B (en)	1986-02-28
FR2436138A1 (en)	1980-04-11
GB1598628A (en)	1981-09-23
GR73860B (en)	1984-05-08
JPS5639313B2 (en)	1981-09-11
IE47543B1 (en)	1984-04-18
YU40625B (en)	1986-02-28
DD140038A5 (en)	1980-02-06
NO791637L (en)	1978-12-05
SE8401491L (en)	1984-03-16
MY8500452A (en)	1985-12-31
GB1598630A (en)	1981-09-23
CY1231A (en)	1984-06-29
YU215582A (en)	1983-02-28
DE2824066A1 (en)	1978-12-14
FR2436138B1 (en)	1982-12-03
SE7806525A (en)	1978-12-04
MY8500451A (en)	1985-12-31
IL54819A (en)	1983-03-31
YU129778A (en)	1983-02-28
HK38084A (en)	1984-05-11
CY1230A (en)	1984-06-29
FR2401143A1 (en)	1979-03-23
SE443784B (en)	1986-03-10
CY1229A (en)	1984-06-29
AR222797A1 (en)	1981-06-30

Publication	Publication Date	Title
IT1197455B (en)	1988-11-30	COMPOSITION FOR COATINGS WHICH CONTAINS POLYVINYLETERE PERFLUORIDE COPOLYMERS
HK73785A (en)	1985-10-04	Pharmaceutical compositions
GB2003028B (en)	1982-02-03	Pharmaceutical compositions
SE7808336L (en)	1979-02-04	CATAPHORETIC VALUABLE COATING COMPOSITION
EP0002259A3 (en)	1979-06-27	Hydantoin derivatives and salts thereof, their synthesis and intermediates, and pharmaceutical formulations
AR223313A1 (en)	1981-08-14	HERBICIDAL COMPOSITION FOR HUMECTABLE POWDER FORMULATIONS
DE2862482D1 (en)	1987-01-08	Use of alpha-polyolefin compositions for extrusion
IT7869316A0 (en)	1978-10-05	PROCEDURE FOR THE PREPARATION OF IMIDAZOLE COMPOUNDS PARTICULARLY USEFUL AS PSYCHODRUGS
IT1107212B (en)	1985-11-25	COMPOSITIONS FOR ZOOTECHNICAL USE
NZ187376A (en)	1981-05-29	N-cyano-n-(2-(4-methyl-5-imidazolyl)methylthio)ethyl)-n-alkynyl guanidines intermediates pharmaceutical compositions
IT1095358B (en)	1985-08-10	THERMOINDURABLE COATING MIXTURE
GB2058818B (en)	1982-11-10	Spray adhesive compositions
GB2008403B (en)	1982-07-28	Pharmaceutical compositions
JPS5495571A (en)	1979-07-28	Hydantoin compound
NZ186334A (en)	1980-05-08	Oxadiazolopyrimidines:pharmaceutical compositions
NZ187852A (en)	1981-03-16	Acylamido-3-cephem -4-carboxylic acids pharmaceutical compositions intermediates
IT7825505A0 (en)	1978-07-10	PROCEDURE FOR MONOALKYLATION OF DI-HYDROXYBENZOLS
GB2008408B (en)	1982-03-17	Pharmaceutical compositions
IT1113111B (en)	1986-01-20	PROCESS PERFECTED FOR THE PREPARATION OF ALFA, DIAMMINE RANGE
NZ190862A (en)	1981-11-19	N-(3-phenylpropyl)-2-hydroxy-2-phenylethlamines pharmaceutical compositions intermediates
IT7849555A0 (en)	1978-05-25	PROCEDURE FOR THE PREPARATION OF MONOHYDROCARBILE TIN TRIAHALIDES
JPS5443237A (en)	1979-04-05	Composition for coating
HK31982A (en)	1982-07-16	Applicator for creasse-setting compositions
IL54687A0 (en)	1978-07-31	Pharmaceutical compositions comprising nitroimidazoles
IT1119282B (en)	1986-03-10	PROCEDURE FOR THE MANUFACTURE OF BETA ALKALINE ALUMINUM PARTS