NO985683L - Leptin (ob protein) fragments - Google Patents

Leptin (ob protein) fragments

Info

Publication number
NO985683L
NO985683L NO985683A NO985683A NO985683L NO 985683 L NO985683 L NO 985683L NO 985683 A NO985683 A NO 985683A NO 985683 A NO985683 A NO 985683A NO 985683 L NO985683 L NO 985683L
Authority
NO
Norway
Prior art keywords
leptin
fragments
protein
Prior art date
Application number
NO985683A
Other languages
Norwegian (no)
Other versions
NO985683D0 (en
Inventor
Kamal A Al-Barazanji
Jonathan Robert Sanders Arch
Patrick Camilleri
William Arthur Neville
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9611775.9A external-priority patent/GB9611775D0/en
Priority claimed from GBGB9618540.0A external-priority patent/GB9618540D0/en
Priority claimed from GBGB9703493.8A external-priority patent/GB9703493D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO985683L publication Critical patent/NO985683L/en
Publication of NO985683D0 publication Critical patent/NO985683D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO985683A 1996-06-06 1998-12-04 Leptin (ob protein) fragments NO985683D0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9611775.9A GB9611775D0 (en) 1996-06-06 1996-06-06 Novel compounds
GBGB9618540.0A GB9618540D0 (en) 1996-09-05 1996-09-05 Novel compounds
GBGB9703493.8A GB9703493D0 (en) 1997-02-20 1997-02-20 Novel compounds
PCT/EP1997/002968 WO1997046585A2 (en) 1996-06-06 1997-06-04 Fragments of leptin (ob protein)

Publications (2)

Publication Number Publication Date
NO985683L true NO985683L (en) 1998-12-04
NO985683D0 NO985683D0 (en) 1998-12-04

Family

ID=27268305

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985683A NO985683D0 (en) 1996-06-06 1998-12-04 Leptin (ob protein) fragments

Country Status (15)

Country Link
EP (1) EP0912609A2 (en)
JP (1) JP2000512137A (en)
KR (1) KR20000016402A (en)
CN (1) CN1221426A (en)
AR (1) AR008765A1 (en)
AU (1) AU3337297A (en)
BR (1) BR9709529A (en)
CA (1) CA2257240A1 (en)
CZ (1) CZ397898A3 (en)
IL (1) IL127153A0 (en)
NO (1) NO985683D0 (en)
NZ (1) NZ332879A (en)
PL (1) PL330361A1 (en)
TR (1) TR199802534T2 (en)
WO (1) WO1997046585A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE278952T1 (en) 1998-07-28 2004-10-15 Vlaams Interuniv Inst Biotech LEPTIN-MEDIATED GENE INDUCTION
US6777388B1 (en) 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
US7208572B2 (en) * 1998-08-21 2007-04-24 Albany Medical College Leptin-related peptides
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
CA2388417A1 (en) * 1999-09-22 2001-03-29 Genset Methods of screening for compounds that modulate the lsr-leptin interaction and their use in the prevention and treatment of obesity-related diseases
EP1612221A3 (en) 2000-05-22 2008-07-23 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Receptor-based interaction trap
PL214862B1 (en) 2001-10-22 2013-09-30 Amgen Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment
EP1663294B1 (en) 2003-09-08 2008-03-26 Laboratoires Serono SA Treatment of fibrotic disease
CN1961000B (en) 2004-02-11 2011-05-04 安米林药品公司 Hybrid polypeptides with selectable properties
US7575878B2 (en) 2004-11-18 2009-08-18 Vib Vzw Methods of inhibiting leptin-induced signaling with fibronectin III domain antibodies
CA2597649A1 (en) 2005-02-11 2006-08-17 Amylin Pharmaceuticals, Inc. Gip analog and hybrid polypeptides with selectable properties
US7629315B2 (en) 2005-03-09 2009-12-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Compositions for blocking the inhibitory effect of human CRP on human leptin
BRPI0614649A2 (en) 2005-08-11 2011-04-12 Amylin Pharmaceuticals Inc hybrid polypeptides with selectable properties
CA2617649A1 (en) 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
ES2319048B1 (en) * 2007-06-20 2010-02-10 Universitat De Les Illes Balears USE OF LEPTINE IN THE TREATMENT OF ALTERATIONS IN FOOD HABITS.
US8889622B2 (en) 2007-07-25 2014-11-18 Washington University Methods of inhibiting seizure in a subject
GB2451858A (en) * 2007-08-15 2009-02-18 Sergiy Konovchuk Methods of reducing body fat and treating obesity
ATE546441T1 (en) 2007-12-05 2012-03-15 Astrazeneca Ab PIPERAZINE DERIVATIVES AND THEIR USE AS MODULATORS OF THE LEPTIN RECEPTOR
CN102026975A (en) 2007-12-05 2011-04-20 阿斯利康(瑞典)有限公司 Piperazines as anti-obesity agents
MX2010013355A (en) * 2008-06-04 2010-12-21 Astrazeneca Ab New compounds v.
CN102143747A (en) * 2008-06-04 2011-08-03 阿斯利康(瑞典)有限公司 New pyridine derivatives as leptin receptor modulator mimetics
US20120071401A1 (en) 2009-04-10 2012-03-22 Amylin Pharamaceuticals, Inc. Amylin agonist compounds for estrogen-deficient mammals
ES2602436T3 (en) * 2010-05-11 2017-02-21 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Peptide-based inhibitor of the activation of interleukin 10 or STAT-3
DK3241558T3 (en) 2010-09-28 2021-04-26 Aegerion Pharmaceuticals Inc HIGH RESOLUTION LEPTINES
CN104829707B (en) * 2015-05-06 2017-12-19 广东省生物资源应用研究所 The leptin activity peptide and its encoding gene and application of one CD ring and E spiral region mutations
CN110183530A (en) * 2019-06-21 2019-08-30 深圳市亚辉龙生物科技股份有限公司 Leptin immunogene, hybridoma, monoclonal antibody, polyclonal antibody and application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
CA2211656A1 (en) * 1995-01-31 1996-08-08 Margret B. Basinski Anti-obesity proteins
WO1996023815A1 (en) * 1995-01-31 1996-08-08 Eli Lilly And Company Ob gene product antibodies
US5552523A (en) * 1995-01-31 1996-09-03 Eli Lilly And Company Anti-obesity proteins
AU5539596A (en) * 1995-04-06 1996-10-23 Amylin Pharmaceuticals, Inc. Anti-obesity agents
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
JP2000512137A (en) 2000-09-19
EP0912609A2 (en) 1999-05-06
KR20000016402A (en) 2000-03-25
TR199802534T2 (en) 1999-03-22
NO985683D0 (en) 1998-12-04
AU3337297A (en) 1998-01-05
WO1997046585A2 (en) 1997-12-11
CZ397898A3 (en) 1999-04-14
IL127153A0 (en) 1999-09-22
AR008765A1 (en) 2000-02-23
CN1221426A (en) 1999-06-30
BR9709529A (en) 1999-08-10
CA2257240A1 (en) 1997-12-11
PL330361A1 (en) 1999-05-10
WO1997046585A3 (en) 1998-04-23
NZ332879A (en) 2000-09-29

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application