NO983284D0 - Antikoagolante midler egnet i behandling av trombose - Google Patents

Antikoagolante midler egnet i behandling av trombose

Info

Publication number
NO983284D0
NO983284D0 NO983284A NO983284A NO983284D0 NO 983284 D0 NO983284 D0 NO 983284D0 NO 983284 A NO983284 A NO 983284A NO 983284 A NO983284 A NO 983284A NO 983284 D0 NO983284 D0 NO 983284D0
Authority
NO
Norway
Prior art keywords
thrombosis
treatment
anticoagulants suitable
anticoagulants
Prior art date
Application number
NO983284A
Other languages
English (en)
Other versions
NO983284L (no
Inventor
Michael Neal Blackburn
William Robert Church
Giora Zeev Feuerstein
Mitchell Stuart Gross
Andrew John Nichols
Eduardo Augustin Padlan
Arunbhai Haribhai Patel
Daniel Robert Sylvester
Original Assignee
Smithkline Beecham Corp
Univ Vermont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Univ Vermont filed Critical Smithkline Beecham Corp
Publication of NO983284D0 publication Critical patent/NO983284D0/no
Publication of NO983284L publication Critical patent/NO983284L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19983284A 1996-01-17 1998-07-16 Anvendelse av et anti-faktor 1X monoklonalt antistoff og en nukleinsyre som koder for et monoklonalt antistoff for fremstilling av et medikament for behandling av trombose- og emboli-assosierte lidelser. NO983284L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1010896P 1996-01-17 1996-01-17
US2911996P 1996-10-24 1996-10-24
PCT/US1997/000759 WO1997026010A1 (en) 1996-01-17 1997-01-17 Anticoagulant agents useful in treatment of thrombosis

Publications (2)

Publication Number Publication Date
NO983284D0 true NO983284D0 (no) 1998-07-16
NO983284L NO983284L (no) 1998-09-16

Family

ID=26680794

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19983284A NO983284L (no) 1996-01-17 1998-07-16 Anvendelse av et anti-faktor 1X monoklonalt antistoff og en nukleinsyre som koder for et monoklonalt antistoff for fremstilling av et medikament for behandling av trombose- og emboli-assosierte lidelser.

Country Status (26)

Country Link
US (5) US6005091A (no)
EP (2) EP1007089B1 (no)
JP (2) JP2000503210A (no)
KR (1) KR100553629B1 (no)
CN (1) CN1213312A (no)
AR (1) AR005658A1 (no)
AT (1) ATE330630T1 (no)
AU (1) AU706397B2 (no)
BR (1) BR9707049A (no)
CZ (1) CZ299452B6 (no)
DE (1) DE69736197T2 (no)
DK (1) DK1007089T3 (no)
ES (1) ES2267131T3 (no)
HK (1) HK1029513A1 (no)
HU (1) HU225903B1 (no)
ID (1) ID17156A (no)
IL (1) IL125380A0 (no)
MA (1) MA24512A1 (no)
MX (1) MX9805810A (no)
NO (1) NO983284L (no)
NZ (2) NZ331014A (no)
PL (1) PL187274B1 (no)
PT (1) PT1007089E (no)
SI (1) SI1007089T1 (no)
TR (1) TR199801390T2 (no)
WO (1) WO1997026010A1 (no)

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MA24512A1 (fr) * 1996-01-17 1998-12-31 Univ Vermont And State Agrienl Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
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US6818749B1 (en) 1998-10-31 2004-11-16 The United States Of America As Represented By The Department Of Health And Human Services Variants of humanized anti carcinoma monoclonal antibody cc49
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US7829085B2 (en) 1999-07-14 2010-11-09 Life Sciences Research Partners Vzw Methods of treating hemostasis disorders using antibodies binding the C1 domain of factor VIII
AT411997B (de) 1999-09-14 2004-08-26 Baxter Ag Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate
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EP1330544A4 (en) * 2000-09-26 2005-04-06 Univ Duke RNA APTAMERS AND METHOD OF IDENTIFYING SAID APTAMERS
DE60236386D1 (de) 2001-01-11 2010-07-01 D Collen Res Foundation Vzw Verfahren und pharmazeutische Zusammensetzung zur Vorbeugung und/oder Behandlung des Syndroms der systemischen entzündlichen Reaktion
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US20040052779A1 (en) * 2001-12-21 2004-03-18 Stinson Jeffrey R. Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria
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JP5620626B2 (ja) 2005-03-31 2014-11-05 中外製薬株式会社 会合制御によるポリペプチド製造方法
US9670269B2 (en) 2006-03-31 2017-06-06 Chugai Seiyaku Kabushiki Kaisha Methods of modifying antibodies for purification of bispecific antibodies
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JP5500730B2 (ja) 2007-09-13 2014-05-21 デレネックス セラピューティクス アーゲー β−アミロイドペプチドに対するヒト化抗体
DK2202245T3 (en) 2007-09-26 2016-11-21 Chugai Pharmaceutical Co Ltd A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR
US8187591B2 (en) * 2007-10-11 2012-05-29 The Regents Of The University Of California Methods of treating coagulopathy
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RU2758952C1 (ru) 2013-09-27 2021-11-03 Чугаи Сейяку Кабусики Кайся Способ получения полипептидного гетеромультимера
NZ728425A (en) 2014-08-07 2022-05-27 Novartis Ag Angiopoietin-like 4 antibodies and methods of use
US9988443B2 (en) 2014-08-07 2018-06-05 Novartis Ag Angiopoetin-like 4 (ANGPTL4) antibodies and methods of use
TWI701435B (zh) 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定ｆｖｉｉｉ的反應性之方法
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第ｖｉｉｉ凝血因子（ｆｖｉｉｉ）機能替代活性的物質之抗體
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KR20180091918A (ko) 2015-12-28 2018-08-16 추가이 세이야쿠 가부시키가이샤 Fc 영역 함유 폴리펩타이드의 정제를 효율화하기 위한 방법
JOP20170013B1 (ar) 2016-01-22 2021-08-17 Merck Sharp & Dohme أجسام xi مضادة لعامل مضاد للتجلط
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AU2017383537A1 (en) * 2016-12-23 2019-06-27 Novartis Ag Methods of treatment with anti-factor XI/XIa antibodies
US11168147B2 (en) 2016-12-23 2021-11-09 Novartis Ag Factor XI antibodies and methods of use
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GB201709970D0 (en) * 2017-06-22 2017-08-09 Kymab Ltd Bispecific antigen-binding molecules
CR20210381A (es) 2017-09-29 2021-09-09 Chugai Pharmaceutical Co Ltd MOLÉCULA DE UNIÓN AL ANTÍGENO MULTIESPECÍFICA QUE TIENE ACTIVIDAD DE SUSTITUCIÓN DE LA FUNCIÓN DE COFACTOR DEL FACTOR VIII DE COAGULACIÓN DE SANGRE (FVIII) Y FORMULACIÓN FARMACÉUTICA QUE CONTIENE TAL MOLÉCULA COMO INGREDIENTE (Divisional Exp. 2020-0158)
DK3723858T3 (da) 2018-12-21 2022-01-24 Kymab Ltd Fixaxfx bispecifik antistof med fælles let kæde

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MA24512A1 (fr) * 1996-01-17 1998-12-31 Univ Vermont And State Agrienl Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
US20070190059A1 (en) * 1996-01-17 2007-08-16 Smithkline Beecham Corporation Antithrombotic agents

Also Published As

Publication number Publication date
DK1007089T3 (da) 2006-10-09
PL327929A1 (en) 1999-01-04
TR199801390T2 (xx) 1998-12-21
CN1213312A (zh) 1999-04-07
WO1997026010A1 (en) 1997-07-24
KR19990077329A (ko) 1999-10-25
ES2267131T3 (es) 2007-03-01
EP1832297A1 (en) 2007-09-12
HUP9900396A3 (en) 2001-10-29
US6391299B1 (en) 2002-05-21
MA24512A1 (fr) 1998-12-31
KR100553629B1 (ko) 2006-10-04
US6005091A (en) 1999-12-21
US20070224198A1 (en) 2007-09-27
ATE330630T1 (de) 2006-07-15
AU706397B2 (en) 1999-06-17
CZ222598A3 (cs) 2000-01-12
HK1029513A1 (en) 2001-04-06
HU225903B1 (en) 2007-12-28
DE69736197T2 (de) 2007-06-21
US20070003553A1 (en) 2007-01-04
NZ501215A (en) 2001-04-27
MX9805810A (es) 1998-11-30
IL125380A0 (en) 1999-03-12
EP1007089A4 (en) 2003-04-16
EP1007089B1 (en) 2006-06-21
PL187274B1 (pl) 2004-06-30
HUP9900396A2 (hu) 1999-05-28
SI1007089T1 (sl) 2006-12-31
BR9707049A (pt) 2000-10-24
ID17156A (id) 1997-12-04
PT1007089E (pt) 2006-11-30
US20020146411A1 (en) 2002-10-10
JP2000503210A (ja) 2000-03-21
JP2007325602A (ja) 2007-12-20
AU1830897A (en) 1997-08-11
NO983284L (no) 1998-09-16
EP1007089A1 (en) 2000-06-14
NZ331014A (en) 2000-01-28
DE69736197D1 (de) 2006-08-03
CZ299452B6 (cs) 2008-07-30
AR005658A1 (es) 1999-07-14

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