NO982302L - Pharmaceutical composition - Google Patents

Pharmaceutical composition

Info

Publication number
NO982302L
NO982302L NO982302A NO982302A NO982302L NO 982302 L NO982302 L NO 982302L NO 982302 A NO982302 A NO 982302A NO 982302 A NO982302 A NO 982302A NO 982302 L NO982302 L NO 982302L
Authority
NO
Norway
Prior art keywords
pharmaceutical composition
essentially
optionally
molecular weight
low molecular
Prior art date
Application number
NO982302A
Other languages
Norwegian (no)
Other versions
NO982302D0 (en
Inventor
Rose James Macrae
Janet Sarah Smith
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of NO982302D0 publication Critical patent/NO982302D0/en
Publication of NO982302L publication Critical patent/NO982302L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates

Abstract

Det er beskrevet en farmasøytisk formulering for oral administrasjon med kontrollert frigjøring, og som omfatter i hovedsak: en aktiv forbindelse, lavmolekylvekts polyetylenoksyd; hydroksypropyl - metyl-cellulose; tabletterenede eksipienter samt eventuelt en eller flere enteriske polymere. Slike formuleringer gir en konstant frigjøringshastighet av medikament i in vitro-modeller av mage-tarm- kanalen.A pharmaceutical formulation for controlled-release oral administration is disclosed, comprising essentially: an active compound, low molecular weight polyethylene oxide; hydroxypropyl methyl cellulose; tableted excipients and optionally one or more enteric polymers. Such formulations provide a constant drug release rate in in vitro gastrointestinal tract models.

NO982302A 1995-11-21 1998-05-20 Pharmaceutical composition NO982302L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9523752.5A GB9523752D0 (en) 1995-11-21 1995-11-21 Pharmaceutical formulations
PCT/EP1996/005020 WO1997018814A1 (en) 1995-11-21 1996-11-11 Pharmaceutical formulations

Publications (2)

Publication Number Publication Date
NO982302D0 NO982302D0 (en) 1998-05-20
NO982302L true NO982302L (en) 1998-07-17

Family

ID=10784188

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982302A NO982302L (en) 1995-11-21 1998-05-20 Pharmaceutical composition

Country Status (29)

Country Link
EP (1) EP0862437A1 (en)
JP (1) JPH10513481A (en)
KR (1) KR19990071505A (en)
CN (1) CN1215993A (en)
AP (1) AP718A (en)
AR (1) AR004335A1 (en)
AU (1) AU709560B2 (en)
BG (1) BG102438A (en)
BR (1) BR9611626A (en)
CA (1) CA2232715A1 (en)
CO (1) CO4480020A1 (en)
CZ (1) CZ155498A3 (en)
GB (1) GB9523752D0 (en)
HR (1) HRP960554A2 (en)
HU (1) HUP9903734A3 (en)
IS (1) IS4706A (en)
MA (1) MA26410A1 (en)
MX (1) MX9804008A (en)
NO (1) NO982302L (en)
NZ (1) NZ322053A (en)
OA (1) OA10687A (en)
PE (1) PE22898A1 (en)
PL (1) PL326981A1 (en)
SK (1) SK63098A3 (en)
TN (1) TNSN96141A1 (en)
TR (1) TR199800902T2 (en)
WO (1) WO1997018814A1 (en)
YU (1) YU62096A (en)
ZA (1) ZA969722B (en)

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Also Published As

Publication number Publication date
TR199800902T2 (en) 1998-09-21
MX9804008A (en) 1998-09-30
HUP9903734A2 (en) 2000-03-28
CA2232715A1 (en) 1997-05-29
ZA969722B (en) 1998-05-20
KR19990071505A (en) 1999-09-27
AU709560B2 (en) 1999-09-02
HRP960554A2 (en) 1998-02-28
JPH10513481A (en) 1998-12-22
YU62096A (en) 1999-03-04
TNSN96141A1 (en) 2005-03-15
WO1997018814A1 (en) 1997-05-29
SK63098A3 (en) 1999-05-07
HUP9903734A3 (en) 2000-04-28
NO982302D0 (en) 1998-05-20
CN1215993A (en) 1999-05-05
MA26410A1 (en) 2004-12-20
IS4706A (en) 1998-03-31
BG102438A (en) 1999-01-29
AU7572196A (en) 1997-06-11
PL326981A1 (en) 1998-11-09
PE22898A1 (en) 1998-05-07
EP0862437A1 (en) 1998-09-09
CZ155498A3 (en) 1999-03-17
GB9523752D0 (en) 1996-01-24
BR9611626A (en) 1999-06-01
AP718A (en) 1999-01-06
OA10687A (en) 2002-11-27
CO4480020A1 (en) 1997-07-09
AR004335A1 (en) 1998-11-04
NZ322053A (en) 1999-11-29
AP9600883A0 (en) 1997-01-31

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