NO981748L - Nytt DNA, samt en fremgangsmÕte for fremstilling av protein ved anvendelse av dette - Google Patents

Nytt DNA, samt en fremgangsmÕte for fremstilling av protein ved anvendelse av dette

Info

Publication number
NO981748L
NO981748L NO981748A NO981748A NO981748L NO 981748 L NO981748 L NO 981748L NO 981748 A NO981748 A NO 981748A NO 981748 A NO981748 A NO 981748A NO 981748 L NO981748 L NO 981748L
Authority
NO
Norway
Prior art keywords
well
new dna
protein
producing protein
producing
Prior art date
Application number
NO981748A
Other languages
English (en)
Other versions
NO981748D0 (no
Inventor
Nobuaki Nakagawa
Hisataka Yasuda
Tomonori Morinaga
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Publication of NO981748D0 publication Critical patent/NO981748D0/no
Publication of NO981748L publication Critical patent/NO981748L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

DNA med nukleotidsekvenser ifølge SEKV.ID NR: l Og nr. 2 i sekvenstabellen og en fremgangsmåte for fremstilling av et protein som omfatter innføyelse av disse DNA i ekspresjons- vektorer for derved å produsere et protein med molekylvekter på ca. 60 kD (under reduserende betingelser) og ca. 60 kD og 120 kD (under ikke-reduserende betingelser), og som er i stand til å inhibere dannelse av osteoklaster. Disse proteiner er anvendelige ved be- handling av osteoporose og reumatisme.
NO981748A 1996-08-19 1998-04-17 Nytt DNA, samt en fremgangsmÕte for fremstilling av protein ved anvendelse av dette NO981748L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8235928A JPH1057071A (ja) 1996-08-19 1996-08-19 新規ｄｎａ及びそれを用いた蛋白質の製造方法
PCT/JP1997/002859 WO1998007840A1 (fr) 1996-08-19 1997-08-19 Nouveaux adn et procede de production de proteines a l'aide de ces derniers

Publications (2)

Publication Number Publication Date
NO981748D0 NO981748D0 (no) 1998-04-17
NO981748L true NO981748L (no) 1998-06-18

Family

ID=16993321

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981748A NO981748L (no) 1996-08-19 1998-04-17 Nytt DNA, samt en fremgangsmÕte for fremstilling av protein ved anvendelse av dette

Country Status (12)

Country Link
EP (1) EP0874045A1 (no)
JP (1) JPH1057071A (no)
KR (1) KR20000064276A (no)
CN (1) CN1198776A (no)
AU (1) AU718458B2 (no)
CA (1) CA2235148A1 (no)
FI (1) FI980853A (no)
HU (1) HUP0001837A3 (no)
NO (1) NO981748L (no)
NZ (1) NZ330400A (no)
WO (1) WO1998007840A1 (no)
ZA (1) ZA977402B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117175A (en) 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US6919434B1 (en) 1995-02-20 2005-07-19 Sankyo Co., Ltd. Monoclonal antibodies that bind OCIF
DK0951551T4 (da) 1996-12-23 2012-09-10 Immunex Corp Ligand for NF-kappa B-receptoraktivator, ligand er medlem af TNF-superfamilien
WO1999058674A2 (en) 1998-05-14 1999-11-18 Immunex Corporation Method of inhibiting osteoclast activity
HU229476B1 (en) * 1997-04-15 2014-01-28 Daiichi Sankyo Company Antibodies against obm
RO128635A2 (ro) 1997-04-16 2013-07-30 Amgen Inc. Anticorp sau fragment al acestuia care se leagă la opgbp şi utilizarea acestuia, utilizarea unei forme solubile de odar, şi metodă de identificare a unui compus care descreşte activitatea opgbp
US6316408B1 (en) 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
CN1183159C (zh) 1997-09-24 2005-01-05 三共株式会社 破骨细胞形成抑制因子单克隆抗体、其用途和试剂盒
CN1183961C (zh) 1998-10-28 2005-01-12 三共株式会社 骨代谢异常症治疗剂
AUPQ167599A0 (en) * 1999-07-19 1999-08-12 St. Vincent's Institute Of Medical Research Inhibitor of osteoclast precursor formation
WO2001023562A2 (en) * 1999-09-27 2001-04-05 Eli Lilly And Company Osteoprotegerin regulatory region
EP1377610A2 (en) 2001-04-03 2004-01-07 Société des Produits Nestlé S.A. Osteoprotegerin in milk
KR100942393B1 (ko) 2001-05-25 2010-02-17 휴먼 게놈 사이언시즈, 인코포레이티드 Ｔｒａｉｌ 수용체에 면역특이적으로 결합하는 항체
JP4761710B2 (ja) 2002-04-05 2011-08-31 アムジェン インコーポレイテッド 選択的ｏｐｇｌ経路インヒビターとしてのヒト抗ｏｐｇｌ中和抗体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117175A (en) * 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US6369027B1 (en) * 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin

Also Published As

Publication number Publication date
AU718458B2 (en) 2000-04-13
JPH1057071A (ja) 1998-03-03
MX9803086A (es) 1998-11-29
NO981748D0 (no) 1998-04-17
CN1198776A (zh) 1998-11-11
ZA977402B (en) 1999-02-18
HUP0001837A2 (hu) 2000-09-28
NZ330400A (en) 1999-05-28
FI980853A0 (fi) 1998-04-17
EP0874045A1 (en) 1998-10-28
EP0874045A4 (no) 1998-11-18
KR20000064276A (ko) 2000-11-06
FI980853A (fi) 1998-06-15
HUP0001837A3 (en) 2002-09-30
CA2235148A1 (en) 1998-02-26
AU3866197A (en) 1998-05-11
WO1998007840A1 (fr) 1998-02-26

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