NO980300L - Nye höymolekylære humane MP52 proteiner - Google Patents

Nye höymolekylære humane MP52 proteiner

Info

Publication number
NO980300L
NO980300L NO980300A NO980300A NO980300L NO 980300 L NO980300 L NO 980300L NO 980300 A NO980300 A NO 980300A NO 980300 A NO980300 A NO 980300A NO 980300 L NO980300 L NO 980300L
Authority
NO
Norway
Prior art keywords
proteins
molecular weight
high molecular
new high
hmw
Prior art date
Application number
NO980300A
Other languages
English (en)
Other versions
NO980300D0 (no
Inventor
Michio Kimura
Tomoaki Matsumoto
Mikiko Takahashi
Shinji Kawai
Yukio Fujino
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of NO980300L publication Critical patent/NO980300L/no
Publication of NO980300D0 publication Critical patent/NO980300D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Proteiner betegnet humane HMW MP52, som har aminosyresekvenser fra SEKV. ID NR:l i sekvenslisten, og som produseres av CHO celler, en fremgangsmåte for fremstilling av humane HMW MP52, og et medisinsk preparat inneholdende humane HMW MP52 som aktiv ingrediens. HMW MP52 kan anvendes ved behandling eller forebygging av bensykdommer etc., fordi de fremmer benmorfogenesen.
NO980300A 1995-07-24 1998-01-23 Nye höymolekylære humane MP52 proteiner NO980300D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7218022A JPH0931098A (ja) 1995-07-24 1995-07-24 新規なタンパク質ｈｍｗヒトｍｐ５２
PCT/JP1996/002065 WO1997004095A1 (fr) 1995-07-24 1996-07-24 Nouvelle proteine hmw humaine mp52

Publications (2)

Publication Number Publication Date
NO980300L true NO980300L (no) 1998-01-23
NO980300D0 NO980300D0 (no) 1998-01-23

Family

ID=16713410

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980300A NO980300D0 (no) 1995-07-24 1998-01-23 Nye höymolekylære humane MP52 proteiner

Country Status (10)

Country Link
EP (1) EP0866125A4 (no)
JP (1) JPH0931098A (no)
KR (1) KR19990035881A (no)
CN (1) CN1196087A (no)
AU (1) AU704364B2 (no)
CA (1) CA2224289A1 (no)
HU (1) HUP9901204A3 (no)
NO (1) NO980300D0 (no)
NZ (1) NZ313278A (no)
WO (1) WO1997004095A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11335398A (ja) 1998-05-22 1999-12-07 Hoechst Marion Roussel Kk 新規な骨誘導活性を有する単量体蛋白質およびそれらからなる軟骨・骨疾患の予防および治療薬
US7811793B2 (en) 1996-12-25 2010-10-12 Biopharma Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Process for preparing purified active monomer of bone-derived factor
TW562807B (en) * 1997-04-01 2003-11-21 Chugai Pharmaceutical Co Ltd Novel secretory membrane protein
JP2000004882A (ja) * 1998-06-18 2000-01-11 Hoechst Marion Roussel Kk ヒトｍｐ５２遺伝子プロモーターおよびこれを用いた有用物質の探索法
PL1948689T3 (pl) 2005-11-18 2012-09-28 Biopharm Ges Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Mutanty czynników wzrostu o wysokiej aktywności
EP2598177B1 (en) 2010-07-30 2015-06-17 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH Drug delivery devices and growth factor formulations for accelerated wound healing
EP2537538A1 (en) 2011-06-22 2012-12-26 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH Bioresorbable Wound Dressing
EP2602264A1 (en) 2011-12-05 2013-06-12 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH GDF-5 mutant for inducing cartilage formation
CN114786707A (zh) 2019-12-18 2022-07-22 默克专利股份公司 Gdf-5突变体用于治疗疼痛和软骨破坏的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2153654A1 (en) * 1993-01-12 1994-07-21 Se-Jin Lee Growth differentiation factor-5
IL110589A0 (en) * 1993-08-10 1994-11-11 Bioph Biotech Entw Pharm Gmbh Growth/differentiation factor of the TGF- beta family
WO1996014335A1 (en) * 1994-11-07 1996-05-17 The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Health And Human Services Cartilage-derived morphogenetic proteins

Also Published As

Publication number Publication date
JPH0931098A (ja) 1997-02-04
NZ313278A (en) 1999-09-29
HUP9901204A2 (hu) 1999-07-28
MX9800686A (es) 1998-10-31
AU704364B2 (en) 1999-04-22
HUP9901204A3 (en) 2000-06-28
WO1997004095A1 (fr) 1997-02-06
EP0866125A1 (en) 1998-09-23
AU6530496A (en) 1997-02-18
CA2224289A1 (en) 1997-02-06
CN1196087A (zh) 1998-10-14
KR19990035881A (ko) 1999-05-25
EP0866125A4 (en) 2001-10-10
NO980300D0 (no) 1998-01-23

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