NO974179L - Rekombinante viruser som uttrykker lecitin-kolesterol-acyltransferase, og anvendelse derav i genterapi - Google Patents
Rekombinante viruser som uttrykker lecitin-kolesterol-acyltransferase, og anvendelse derav i genterapiInfo
- Publication number
- NO974179L NO974179L NO974179A NO974179A NO974179L NO 974179 L NO974179 L NO 974179L NO 974179 A NO974179 A NO 974179A NO 974179 A NO974179 A NO 974179A NO 974179 L NO974179 L NO 974179L
- Authority
- NO
- Norway
- Prior art keywords
- gene therapy
- recombinant viruses
- cholesterol acyltransferase
- viruses expressing
- lecithin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9502943A FR2731710B1 (fr) | 1995-03-14 | 1995-03-14 | Virus recombinants exprimant la lecithine cholesterol acyltransferase et utilisations en therapie genique |
PCT/FR1996/000381 WO1996028553A1 (fr) | 1995-03-14 | 1996-03-12 | Virus recombinants exprimant la lecithine cholesterol acyltransferase et utilisation en therapie genique |
Publications (2)
Publication Number | Publication Date |
---|---|
NO974179D0 NO974179D0 (no) | 1997-09-10 |
NO974179L true NO974179L (no) | 1997-09-10 |
Family
ID=9477007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO974179A NO974179L (no) | 1995-03-14 | 1997-09-10 | Rekombinante viruser som uttrykker lecitin-kolesterol-acyltransferase, og anvendelse derav i genterapi |
Country Status (15)
Country | Link |
---|---|
US (1) | US20010014319A1 (no) |
EP (1) | EP0815239A1 (no) |
JP (1) | JPH11501518A (no) |
KR (1) | KR19980703008A (no) |
AU (1) | AU711381B2 (no) |
BR (1) | BR9607757A (no) |
CA (1) | CA2214010A1 (no) |
CZ (1) | CZ286897A3 (no) |
FR (1) | FR2731710B1 (no) |
HU (1) | HUP9801214A3 (no) |
IL (1) | IL117466A0 (no) |
NO (1) | NO974179L (no) |
SK (1) | SK124897A3 (no) |
WO (1) | WO1996028553A1 (no) |
ZA (1) | ZA961998B (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE353957T1 (de) * | 1995-11-09 | 2007-03-15 | Us Gov Health & Human Serv | Verwendung von lezithin-cholesterin- azetyltransferase für die behandlung von atherosklerose |
FR2755975B1 (fr) * | 1996-11-15 | 1999-05-07 | Rhone Poulenc Rorer Sa | Virus recombinants bicistroniques utiles pour le traitement de pathologies liees aux dyslipoproteinemies |
CA2284832A1 (en) | 1997-04-11 | 1998-10-22 | Takeda Chemical Industries, Ltd. | Proteins having lecithin-cholesterol acyltransferase-like activity, their production and use |
EP1428041A4 (en) * | 2001-06-19 | 2007-01-17 | Paxflow Holdings Pte Ltd | LOCATION, COMMUNICATION AND PURSUIT SYSTEMS |
MXPA04012859A (es) | 2002-06-18 | 2005-03-31 | Eisai Co Ltd | Adipocitos primariamente cultivados para terapia de gen. |
CA2654608A1 (en) * | 2006-06-07 | 2007-12-13 | Reddy Us Therapeutics, Inc. | Compositions and methods to enhance reverse cholesterol transport |
CA2654661C (en) | 2006-06-26 | 2012-10-23 | Amgen Inc. | Compositions comprising modified lcat and use thereof for treating atherosclerosis |
WO2008108344A1 (ja) * | 2007-03-02 | 2008-09-12 | Cellgentech, Inc. | Lcat欠損症の遺伝子治療用細胞並びにこれを産生するのに用いられる複製欠損性レトロウイルスベクター及びプラスミド |
JP6952112B2 (ja) | 2016-09-20 | 2021-10-20 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | 新規なehv挿入部位orf70 |
CN110072546B (zh) | 2016-09-20 | 2023-10-31 | 勃林格殷格翰动物保健有限公司 | 新的猪流感疫苗 |
TWI780070B (zh) | 2016-09-20 | 2022-10-11 | 德商百靈佳殷格翰維美迪加股份有限公司 | 新穎之啟動子 |
CA3036386A1 (en) | 2016-09-20 | 2018-03-29 | Boehringer Ingelheim Vetmedica Gmbh | Canine adenovirus vectors |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8424757D0 (en) * | 1984-10-01 | 1984-11-07 | Pasteur Institut | Retroviral vector |
US5049488A (en) * | 1985-11-08 | 1991-09-17 | Genentech, Inc. | Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase |
US5252479A (en) * | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
FR2705361B1 (fr) * | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
CN1115414C (zh) * | 1993-07-13 | 2003-07-23 | 罗纳-布朗克罗莱尔股份有限公司 | 用于基因治疗的病毒载体 |
-
1995
- 1995-03-14 FR FR9502943A patent/FR2731710B1/fr not_active Expired - Fee Related
-
1996
- 1996-03-12 AU AU50082/96A patent/AU711381B2/en not_active Ceased
- 1996-03-12 CA CA002214010A patent/CA2214010A1/fr not_active Abandoned
- 1996-03-12 WO PCT/FR1996/000381 patent/WO1996028553A1/fr not_active Application Discontinuation
- 1996-03-12 HU HU9801214A patent/HUP9801214A3/hu unknown
- 1996-03-12 US US08/913,699 patent/US20010014319A1/en not_active Abandoned
- 1996-03-12 KR KR1019970706416A patent/KR19980703008A/ko not_active Application Discontinuation
- 1996-03-12 CZ CZ972868A patent/CZ286897A3/cs unknown
- 1996-03-12 EP EP96906816A patent/EP0815239A1/fr not_active Withdrawn
- 1996-03-12 ZA ZA961998A patent/ZA961998B/xx unknown
- 1996-03-12 BR BR9607757A patent/BR9607757A/pt not_active Application Discontinuation
- 1996-03-12 JP JP8527333A patent/JPH11501518A/ja not_active Ceased
- 1996-03-12 SK SK1248-97A patent/SK124897A3/sk unknown
- 1996-03-13 IL IL11746696A patent/IL117466A0/xx unknown
-
1997
- 1997-09-10 NO NO974179A patent/NO974179L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUP9801214A2 (hu) | 1998-08-28 |
FR2731710B1 (fr) | 1997-04-30 |
CA2214010A1 (fr) | 1996-09-19 |
SK124897A3 (en) | 1998-02-04 |
US20010014319A1 (en) | 2001-08-16 |
NO974179D0 (no) | 1997-09-10 |
BR9607757A (pt) | 1999-01-26 |
FR2731710A1 (fr) | 1996-09-20 |
WO1996028553A1 (fr) | 1996-09-19 |
AU5008296A (en) | 1996-10-02 |
HUP9801214A3 (en) | 2000-08-28 |
JPH11501518A (ja) | 1999-02-09 |
MX9706569A (es) | 1997-11-29 |
CZ286897A3 (en) | 1997-12-17 |
EP0815239A1 (fr) | 1998-01-07 |
IL117466A0 (en) | 1996-07-23 |
AU711381B2 (en) | 1999-10-14 |
KR19980703008A (ko) | 1998-09-05 |
ZA961998B (en) | 1996-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |