NO965528L - Use of enantiomers of oxazophosphorins such as ifosfamide, in anti-cancer therapy to reduce side effects - Google Patents

Use of enantiomers of oxazophosphorins such as ifosfamide, in anti-cancer therapy to reduce side effects

Info

Publication number
NO965528L
NO965528L NO965528A NO965528A NO965528L NO 965528 L NO965528 L NO 965528L NO 965528 A NO965528 A NO 965528A NO 965528 A NO965528 A NO 965528A NO 965528 L NO965528 L NO 965528L
Authority
NO
Norway
Prior art keywords
ifosfamide
enantiomers
oxazophosphorins
side effects
cancer therapy
Prior art date
Application number
NO965528A
Other languages
Norwegian (no)
Other versions
NO965528D0 (en
Inventor
Helen Frances Baker
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB1994/002171 external-priority patent/WO1996000075A1/en
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Publication of NO965528D0 publication Critical patent/NO965528D0/en
Publication of NO965528L publication Critical patent/NO965528L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Et produkt som inneholder respektive enantiomerer av et oksazo- fosforin, hver av disse hovedsakelig fri fra den andre, som et kombinert preparat for separat simultan elier sekvensiell bruk i antikreft terapi. Den aktive komponent kan være ifosfamid. Levo-ifosfamid er foretrukket for monomedikamentell behandling, på grunn av denne antiomers raskere metabolisme.A product containing respective enantiomers of an oxazophosphorin, each substantially free of the other, as a combined preparation for separate simultaneous or sequential use in anticancer therapy. The active component may be ifosfamide. Levo-ifosfamide is preferred for mono-drug treatment, due to the faster metabolism of this antioem.

NO965528A 1994-06-23 1996-12-20 Use of enantiomers of oxazophosphorins such as ifosfamide, in anti-cancer therapy to reduce side effects NO965528L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9412618A GB9412618D0 (en) 1994-06-23 1994-06-23 Cytotoxic agent and its use
PCT/GB1994/002171 WO1996000075A1 (en) 1994-06-23 1994-10-05 Use of the enantiomers of ifosfamide in antitumor therapy for reducing side effects
PCT/GB1995/001475 WO1996000076A1 (en) 1994-06-23 1995-06-23 Use of the enantiomers of oxazophosphorines, e.g. ifosfamide, in anti-tumour therapy, for reducing side-effects

Publications (2)

Publication Number Publication Date
NO965528D0 NO965528D0 (en) 1996-12-20
NO965528L true NO965528L (en) 1997-02-19

Family

ID=10757213

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965528A NO965528L (en) 1994-06-23 1996-12-20 Use of enantiomers of oxazophosphorins such as ifosfamide, in anti-cancer therapy to reduce side effects

Country Status (6)

Country Link
EP (1) EP0772444A1 (en)
AU (1) AU2747495A (en)
FI (1) FI965171A0 (en)
GB (1) GB9412618D0 (en)
NO (1) NO965528L (en)
WO (1) WO1996000076A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1164597A (en) * 1995-12-19 1997-07-14 Darwin Discovery Limited Ifosfamide, analogues thereof and their preparation
US6153150A (en) 1998-01-12 2000-11-28 Advanced Technology Materials, Inc. Apparatus and method for controlled decomposition oxidation of gaseous pollutants
US6261524B1 (en) 1999-01-12 2001-07-17 Advanced Technology Materials, Inc. Advanced apparatus for abatement of gaseous pollutants

Also Published As

Publication number Publication date
NO965528D0 (en) 1996-12-20
EP0772444A1 (en) 1997-05-14
FI965171A (en) 1996-12-20
AU2747495A (en) 1996-01-19
GB9412618D0 (en) 1994-08-10
WO1996000076A1 (en) 1996-01-04
FI965171A0 (en) 1996-12-20

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