NO963331D0 - 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister - Google Patents

5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister

Info

Publication number
NO963331D0
NO963331D0 NO963331A NO963331A NO963331D0 NO 963331 D0 NO963331 D0 NO 963331D0 NO 963331 A NO963331 A NO 963331A NO 963331 A NO963331 A NO 963331A NO 963331 D0 NO963331 D0 NO 963331D0
Authority
NO
Norway
Prior art keywords
antagonists
receptor site
benzodiazepine receptor
site agonists
heteroarylindole
Prior art date
Application number
NO963331A
Other languages
English (en)
Other versions
NO963331L (no
Inventor
John E Macor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO963331D0 publication Critical patent/NO963331D0/no
Publication of NO963331L publication Critical patent/NO963331L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO963331A 1994-02-10 1996-08-09 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister NO963331L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19455394A 1994-02-10 1994-02-10
PCT/IB1994/000407 WO1995021836A1 (en) 1994-02-10 1994-12-08 5-heteroarylindole derivatives as benzodiazepine receptor site agonists and antagonists

Publications (2)

Publication Number Publication Date
NO963331D0 true NO963331D0 (no) 1996-08-09
NO963331L NO963331L (no) 1996-10-09

Family

ID=22718035

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963331A NO963331L (no) 1994-02-10 1996-08-09 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister

Country Status (12)

Country Link
US (1) US5688809A (no)
EP (1) EP0743942A1 (no)
JP (1) JP2829788B2 (no)
KR (1) KR970701182A (no)
CN (1) CN1067386C (no)
AU (1) AU685881B2 (no)
CA (1) CA2183084A1 (no)
FI (1) FI950568A (no)
IL (1) IL112519A0 (no)
NO (1) NO963331L (no)
NZ (1) NZ276172A (no)
WO (1) WO1995021836A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU746706B2 (en) 1997-07-03 2002-05-02 Du Pont Pharmaceuticals Company Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
BRPI0413785A (pt) 2003-08-21 2006-11-07 Osi Pharm Inc composto, composição, e, método de tratamento de distúrbio hiperproliferativo
US7442709B2 (en) * 2003-08-21 2008-10-28 Osi Pharmaceuticals, Inc. N3-substituted imidazopyridine c-Kit inhibitors
MXPA06002018A (es) * 2003-08-21 2006-05-31 Osi Pharm Inc Bencimidazolilo n-sustituidos inhibidores de c-kit.
ATE521604T1 (de) * 2004-12-01 2011-09-15 Osi Pharm Inc N-substituierte benzimidazolyl-c-kit-inhibitoren und kombinatorische benzimidazolbibliothek
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
CA2905242C (en) 2013-03-15 2016-11-29 Pfizer Inc. Indole compounds that activate ampk
TWI706952B (zh) 2015-04-29 2020-10-11 比商健生藥品公司 氮雜苯并咪唑類及其作為ａｍｐａ受體調控劑之用途
US10513523B2 (en) 2015-04-29 2019-12-24 Janssen Pharmaceutica Nv Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators
BR112017023200A2 (pt) 2015-04-29 2018-08-07 Janssen Pharmaceutica Nv compostos de indolona e seu uso como moduladores do receptor de ampa
WO2016176449A1 (en) 2015-04-29 2016-11-03 Janssen Pharmaceutica Nv Benzimidazolone and benzothiazolone compounds and their use as ampa receptor modulators
KR101831553B1 (ko) 2017-01-23 2018-02-22 계명대학교 산학협력단 전이성 유방암의 유용한 신규 화합물 및 이의 의학적 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066654A (en) * 1990-10-22 1991-11-19 A. H. Robins Company, Incorporated 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants
GB9210400D0 (en) * 1992-05-15 1992-07-01 Merck Sharp & Dohme Therapeutic agents
TW251284B (no) * 1992-11-02 1995-07-11 Pfizer

Also Published As

Publication number Publication date
JP2829788B2 (ja) 1998-12-02
IL112519A0 (en) 1995-05-26
FI950568A (fi) 1995-08-11
CN1067386C (zh) 2001-06-20
FI950568A0 (fi) 1995-02-09
CA2183084A1 (en) 1995-08-17
KR970701182A (ko) 1997-03-17
US5688809A (en) 1997-11-18
AU685881B2 (en) 1998-01-29
NZ276172A (en) 1998-02-26
AU1033995A (en) 1995-08-29
EP0743942A1 (en) 1996-11-27
NO963331L (no) 1996-10-09
WO1995021836A1 (en) 1995-08-17
JPH09501949A (ja) 1997-02-25
CN1142823A (zh) 1997-02-12

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