NO962841L - Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler - Google Patents

Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler

Info

Publication number: NO962841L
Authority: NO; Norway
Prior art keywords: colon cancer; hydroxy; chemopreventives; phenylazobenzoic acid; acid derivatives
Prior art date: 1994-01-07

Application number

NO962841A

Other languages

English (en)

Norwegian (no)

Other versions

NO962841D0 (no

Inventor

Lorin K Johnson

Marvin H Sleisenger

Original Assignee

Salix Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-07

Filing date

1996-07-05

Publication date

1996-08-29

1996-07-05 Application filed by Salix Pharmaceuticals Inc filed Critical Salix Pharmaceuticals Inc

1996-07-05 Publication of NO962841D0 publication Critical patent/NO962841D0/no

1996-08-29 Publication of NO962841L publication Critical patent/NO962841L/no

Links

206010009944 Colon cancer Diseases 0.000 title abstract 4
208000029742 colonic neoplasm Diseases 0.000 title abstract 4
JHDYSXXPQIFFJZ-UHFFFAOYSA-N chembl1834961 Chemical class C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC=CC=2)=C1 JHDYSXXPQIFFJZ-UHFFFAOYSA-N 0.000 title abstract 3
230000002113 chemopreventative effect Effects 0.000 title abstract 2
239000002246 antineoplastic agent Substances 0.000 title 1
229940127089 cytotoxic agent Drugs 0.000 title 1
239000002207 metabolite Substances 0.000 abstract 4
150000002148 esters Chemical class 0.000 abstract 2
230000003647 oxidation Effects 0.000 abstract 2
238000007254 oxidation reaction Methods 0.000 abstract 2
238000002512 chemotherapy Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO962841A 1994-01-07 1996-07-05 Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler NO962841L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/178,578 US5498608A (en)	1994-01-07	1994-01-07	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
PCT/US1995/000055 WO1995018622A1 (en)	1994-01-07	1995-01-06	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

Publications (2)

Publication Number	Publication Date
NO962841D0 NO962841D0 (no)	1996-07-05
NO962841L true NO962841L (no)	1996-08-29

Family

ID=22653104

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO962841A NO962841L (no)	1994-01-07	1996-07-05	Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler

Country Status (18)

Country	Link
US (1)	US5498608A (ro)
EP (1)	EP0738152B1 (ro)
JP (4)	JPH09510958A (ro)
CN (1)	CN1140994A (ro)
AT (1)	ATE308327T1 (ro)
AU (1)	AU691869B2 (ro)
CA (1)	CA2180571C (ro)
CZ (1)	CZ286460B6 (ro)
DE (1)	DE69534564T2 (ro)
DK (1)	DK0738152T3 (ro)
ES (1)	ES2248796T3 (ro)
FI (1)	FI962735A (ro)
HU (1)	HUT74512A (ro)
NO (1)	NO962841L (ro)
NZ (1)	NZ279062A (ro)
RO (1)	RO116525B1 (ro)
RU (1)	RU2161487C2 (ro)
WO (1)	WO1995018622A1 (ro)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5498608A (en) *	1994-01-07	1996-03-12	Salix Pharmaceuticals	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
US6166024A (en) *	1995-03-30	2000-12-26	Mayo Foundation For Medical Education And Research	Use of topical azathioprine and thioguanine to treat colorectal adenomas
US6231888B1 (en)	1996-01-18	2001-05-15	Perio Products Ltd.	Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
SE9700934D0 (sv) *	1997-03-14	1997-03-14	Astra Ab	New formulation
US5858694A (en) *	1997-05-30	1999-01-12	Cell Pathways, Inc.	Method for identifying compounds for inhibition of cancerous lesions
DE19732903A1 (de)	1997-07-30	1999-02-04	Falk Pharma Gmbh	Pellet-Formulierung zur Behandlung des Intestinaltraktes
EP1105141B1 (de)	1998-08-06	2003-11-05	Wolfgang Stremmel	Phosphatidylcholin als arzneimittel mit schleimhautschützender wirkung
US6531152B1 (en)	1998-09-30	2003-03-11	Dexcel Pharma Technologies Ltd.	Immediate release gastrointestinal drug delivery system
US6632451B2 (en)	1999-06-04	2003-10-14	Dexcel Pharma Technologies Ltd.	Delayed total release two pulse gastrointestinal drug delivery system
JPWO2002000621A1 (ja) *	2000-06-29	2004-04-22	塩野義製薬株式会社	Ｘ型ｓＰＬＡ２阻害作用を有する化合物
ES2254470T3 (es) *	2000-08-29	2006-06-16	Nobex Corporation	Compuestos inmunorreguladores, derivados de los mismos y su uso.
TWI314457B (ro) *	2001-03-19	2009-09-11	Shionogi & Co
US8048924B2 (en) *	2001-08-29	2011-11-01	Biocon Limited	Methods and compositions employing 4-aminophenylacetic acid compounds
US7825132B2 (en)	2002-08-23	2010-11-02	Novartis Vaccines And Diagnostics, Inc.	Inhibition of FGFR3 and treatment of multiple myeloma
JP2006511616A (ja) *	2002-11-13	2006-04-06	カイロンコーポレイション	癌の処置方法およびその関連方法
JP2007520495A (ja) *	2004-02-06	2007-07-26	ボロディートーマスユリウス	下痢型過敏性腸症候群におけるアミノサリチル酸の使用法
WO2005082340A2 (en)	2004-02-20	2005-09-09	Chiron Corporation	Modulation of inflammatory and metastatic processes
FR2867981B1 (fr)	2004-03-24	2008-10-31	Genevrier Sa Lab	Utilisation des chondroitine mono-et disulfates en therapeutique
KR20110121730A (ko) *	2004-05-28	2011-11-08	샐릭스 파마슈티컬스 인코포레이티드	방사선 유발성 장염의 예방, 치료 및 개선 방법
KR20130028807A (ko) *	2004-05-28	2013-03-19	샐릭스 파마슈티컬스 인코포레이티드	방사선 유발성 장염의 예방, 치료 및 개선 방법
HUE028158T2 (en)	2004-07-07	2016-12-28	Biocon Ltd	Synthesis of bound immunoregulatory compounds
SI1885187T1 (sl)	2005-05-13	2013-12-31	Novartis Ag	Postopki za zdravljenje raka, rezistentnega na zdravila
US8921344B2 (en) *	2006-11-03	2014-12-30	Salix Pharmaceuticals, Inc.	Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
EP1931354A4 (en) *	2005-08-24	2010-03-24	Salix Pharmaceuticals Inc	BALSAL ACID FORMULATIONS AND THEIR PREPARATION AND USE
US7452872B2 (en) *	2005-08-24	2008-11-18	Salix Pharmaceuticals, Inc.	Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
RU2354384C1 (ru) *	2007-12-28	2009-05-10	Михаил Владимирович Кутушов	Применение органических красителей в качестве средства для лечения онкологических заболеваний
US8569466B2 (en) *	2008-09-10	2013-10-29	Nnochiri Ekwuribe	Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers
EP2298321A1 (en)	2009-08-26	2011-03-23	Nordic Pharma	Novel pharmaceutical compositions for treating IBD
CA2797560A1 (en)	2010-04-26	2011-11-03	Salix Pharmaceuticals, Ltd.	Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives for the treatment of males
CN116173220A (zh) *	2022-03-02	2023-05-30	上海赛金生物医药有限公司	Ctla-4抑制剂和非类固醇抗炎药的抗癌联合治疗方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2080796B (en) *	1980-07-21	1983-10-12	Biorex Laboratories Ltd	2-hydroxy-5-phenylazobenzoic acid derivatives
US4412992A (en) *	1980-07-21	1983-11-01	Biorex Laboratories Limited	2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith
NZ212419A (en) *	1984-06-25	1988-08-30	Mucan Diagnostics Pty Ltd	In vitro diagnostic test for detecting cancer cells producing mucin antigens
US5162202A (en) *	1989-12-12	1992-11-10	Shamsuddin Abulkalam M	Rectal mucus test and kit for detecting cancerous and precancerous conditions
US5498608A (en) *	1994-01-07	1996-03-12	Salix Pharmaceuticals	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

1994
- 1994-01-07 US US08/178,578 patent/US5498608A/en not_active Expired - Lifetime
1995
- 1995-01-06 NZ NZ279062A patent/NZ279062A/xx unknown
- 1995-01-06 HU HU9601846A patent/HUT74512A/hu unknown
- 1995-01-06 RO RO96-01403A patent/RO116525B1/ro unknown
- 1995-01-06 EP EP95907293A patent/EP0738152B1/en not_active Expired - Lifetime
- 1995-01-06 JP JP7518558A patent/JPH09510958A/ja not_active Withdrawn
- 1995-01-06 CZ CZ19961967A patent/CZ286460B6/cs not_active IP Right Cessation
- 1995-01-06 AT AT95907293T patent/ATE308327T1/de active
- 1995-01-06 DK DK95907293T patent/DK0738152T3/da active
- 1995-01-06 AU AU15575/95A patent/AU691869B2/en not_active Expired
- 1995-01-06 WO PCT/US1995/000055 patent/WO1995018622A1/en active IP Right Grant
- 1995-01-06 CA CA002180571A patent/CA2180571C/en not_active Expired - Fee Related
- 1995-01-06 CN CN95191519A patent/CN1140994A/zh active Pending
- 1995-01-06 RU RU96117041/14A patent/RU2161487C2/ru active
- 1995-01-06 DE DE69534564T patent/DE69534564T2/de not_active Expired - Lifetime
- 1995-01-06 ES ES95907293T patent/ES2248796T3/es not_active Expired - Lifetime
1996
- 1996-07-03 FI FI962735A patent/FI962735A/fi unknown
- 1996-07-05 NO NO962841A patent/NO962841L/no unknown
2005
- 2005-03-14 JP JP2005115075A patent/JP2005320326A/ja not_active Withdrawn
- 2005-03-14 JP JP2005072111A patent/JP4601466B2/ja not_active Expired - Lifetime
2010
- 2010-07-12 JP JP2010157537A patent/JP2010235629A/ja active Pending

Also Published As

Publication number	Publication date
FI962735A (fi)	1996-08-26
DE69534564D1 (de)	2005-12-08
JP2005320326A (ja)	2005-11-17
DE69534564T2 (de)	2006-07-27
JP2006096738A (ja)	2006-04-13
CA2180571C (en)	2001-03-20
EP0738152A4 (en)	2000-12-13
CZ286460B6 (en)	2000-04-12
DK0738152T3 (da)	2006-01-30
US5498608A (en)	1996-03-12
WO1995018622A1 (en)	1995-07-13
JP2010235629A (ja)	2010-10-21
FI962735A0 (fi)	1996-07-03
AU691869B2 (en)	1998-05-28
CA2180571A1 (en)	1995-07-13
HU9601846D0 (en)	1996-09-30
CZ196796A3 (en)	1996-12-11
EP0738152A1 (en)	1996-10-23
RO116525B1 (ro)	2001-03-30
JPH09510958A (ja)	1997-11-04
CN1140994A (zh)	1997-01-22
EP0738152B1 (en)	2005-11-02
AU1557595A (en)	1995-08-01
RU2161487C2 (ru)	2001-01-10
JP4601466B2 (ja)	2010-12-22
ES2248796T3 (es)	2006-03-16
ATE308327T1 (de)	2005-11-15
NZ279062A (en)	1999-11-29
NO962841D0 (no)	1996-07-05
HUT74512A (en)	1997-01-28

Publication	Publication Date	Title
NO962841L (no)	1996-08-29	Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler
TW552137B (en)	2003-09-11	Pharmaceutical compositions for inhibiting oxidation of lipoproteins, scavenging free radicals and inhibiting metal ion chelation of lipoproteins
ATE424810T1 (de)	2009-03-15	Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung
DK0828724T3 (da)	2002-03-04	5-oxygenerede diaryl-2-(5H)-furanoner som COX-2-inhibitorer
NO973059D0 (no)	1997-07-01	Hydroxylaminderivater som er anvendbare for å höyne den molekylære chaperonproduksjon, og fremstilling derav
DK0787489T3 (da)	2003-08-18	Sammensætning, der indeholder propionyl-L-carnitin og hydroxycitronsyre eller pantothensyre
NO950774L (no)	1995-09-04	Fremgangsmåte for inhibering av bentap og nedsettelse av serumkolesterol
TR199900046T2 (xx)	1999-04-21	Se�ici siklooksijenaz-2 inhibit�rleri olarak ikameli piridinler.
UA44254C2 (uk)	2002-02-15	Похідні 4-(заміщеного феніламіно)хіназоліну, спосіб їх одержання, спосіб лікування і фармацевтична композиція
FR2416012A1 (fr)	1979-08-31	Derives de l'imidazole et medicament contenant ces substances
NO944928L (no)	1995-06-22	Fremgangsmåter for inhibering av Alzheimers sykdom
FI951454A (fi)	1995-03-27	1-(2-oksoasetyyli)piperidiini-2-karboksyylihappojohdannaiset monille lääkkeille resistenttien syöpäsolujen herkistäjinä
HUP9803044A2 (hu)	1999-09-28	Ibuprofentartalmú készítmény
DK0957899T3 (da)	2003-04-22	Doseringsform til tilvejebringelse af stigende dosis lægemiddel
FR2362833A1 (fr)	1978-03-24	Nouveaux derives 5 de prostaglandine, leur procede de preparation et medicament les contenant
NO871059D0 (no)	1987-03-13	Nye carboxylsyrederivater, fremgangsmaate for fremstilling av disse, anvendelse derav, saa vel som legemidler inneholdende disse forbindelser.
JPS56145298A (en)	1981-11-11	Aminophenyl derivative and physiologically active preparation containing the same
US7169813B2 (en)	2007-01-30	4-oxo-fenretinide, administered alone and in combination with fenretinide, as preventive and therapeutic agent for cancer
DE59610175D1 (de)	2003-04-03	Hydantoinderivate als zwischenprodukte für pharmazeutische wirkstoffe
JPH02223521A (ja)	1990-09-05	血清コレステロール低下剤
Abergel et al.	2006	Growth arrest and decrease of α-SMA and type I collagen expression by palmitic acid in the rat hepatic stellate cell line PAV-1
Cardini et al.	1968	Systematic application of gas chromatography to the analysis of pharmaceutical preparations
AP9801417A0 (en)	1998-12-31	Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders.
DK0712838T3 (da)	1999-07-19	Acylphenylglycinderivat og forebyggende middel og lægemiddel til sygdomme, der er forårsaget af en forøget kollagenaseaktiv
NO964497L (no)	1996-10-23	Middel for behandling av cor pulmonale