NO962841L - Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler - Google Patents

Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler

Info

Publication number: NO962841L
Authority: NO; Norway
Prior art keywords: colon cancer; hydroxy; chemopreventives; phenylazobenzoic acid; acid derivatives
Prior art date: 1994-01-07

Application number

NO962841A

Other languages

English (en)

Norwegian (no)

Other versions

NO962841D0 (no

Inventor

Lorin K Johnson

Marvin H Sleisenger

Original Assignee

Salix Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-07

Filing date

1996-07-05

Publication date

1996-08-29

1996-07-05 Application filed by Salix Pharmaceuticals Inc filed Critical Salix Pharmaceuticals Inc

1996-07-05 Publication of NO962841D0 publication Critical patent/NO962841D0/no

1996-08-29 Publication of NO962841L publication Critical patent/NO962841L/no

Links

206010009944 Colon cancer Diseases 0.000 title abstract 4
208000029742 colonic neoplasm Diseases 0.000 title abstract 4
JHDYSXXPQIFFJZ-UHFFFAOYSA-N chembl1834961 Chemical class C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC=CC=2)=C1 JHDYSXXPQIFFJZ-UHFFFAOYSA-N 0.000 title abstract 3
230000002113 chemopreventative effect Effects 0.000 title abstract 2
239000002246 antineoplastic agent Substances 0.000 title 1
229940127089 cytotoxic agent Drugs 0.000 title 1
239000002207 metabolite Substances 0.000 abstract 4
150000002148 esters Chemical class 0.000 abstract 2
230000003647 oxidation Effects 0.000 abstract 2
238000007254 oxidation reaction Methods 0.000 abstract 2
238000002512 chemotherapy Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO962841A 1994-01-07 1996-07-05 Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler NO962841L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/178,578 US5498608A (en)	1994-01-07	1994-01-07	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
PCT/US1995/000055 WO1995018622A1 (en)	1994-01-07	1995-01-06	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

Publications (2)

Publication Number	Publication Date
NO962841D0 NO962841D0 (no)	1996-07-05
NO962841L true NO962841L (no)	1996-08-29

Family

ID=22653104

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO962841A NO962841L (no)	1994-01-07	1996-07-05	Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler

Country Status (18)

Country	Link
US (1)	US5498608A (de)
EP (1)	EP0738152B1 (de)
JP (4)	JPH09510958A (de)
CN (1)	CN1140994A (de)
AT (1)	ATE308327T1 (de)
AU (1)	AU691869B2 (de)
CA (1)	CA2180571C (de)
CZ (1)	CZ286460B6 (de)
DE (1)	DE69534564T2 (de)
DK (1)	DK0738152T3 (de)
ES (1)	ES2248796T3 (de)
FI (1)	FI962735A (de)
HU (1)	HUT74512A (de)
NO (1)	NO962841L (de)
NZ (1)	NZ279062A (de)
RO (1)	RO116525B1 (de)
RU (1)	RU2161487C2 (de)
WO (1)	WO1995018622A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5498608A (en) *	1994-01-07	1996-03-12	Salix Pharmaceuticals	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
US6166024A (en) *	1995-03-30	2000-12-26	Mayo Foundation For Medical Education And Research	Use of topical azathioprine and thioguanine to treat colorectal adenomas
US6231888B1 (en)	1996-01-18	2001-05-15	Perio Products Ltd.	Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
SE9700934D0 (sv) *	1997-03-14	1997-03-14	Astra Ab	New formulation
US5858694A (en) *	1997-05-30	1999-01-12	Cell Pathways, Inc.	Method for identifying compounds for inhibition of cancerous lesions
DE19732903A1 (de)	1997-07-30	1999-02-04	Falk Pharma Gmbh	Pellet-Formulierung zur Behandlung des Intestinaltraktes
EP1105141B1 (de)	1998-08-06	2003-11-05	Wolfgang Stremmel	Phosphatidylcholin als arzneimittel mit schleimhautschützender wirkung
US6531152B1 (en)	1998-09-30	2003-03-11	Dexcel Pharma Technologies Ltd.	Immediate release gastrointestinal drug delivery system
US6632451B2 (en)	1999-06-04	2003-10-14	Dexcel Pharma Technologies Ltd.	Delayed total release two pulse gastrointestinal drug delivery system
JPWO2002000621A1 (ja) *	2000-06-29	2004-04-22	塩野義製薬株式会社	Ｘ型ｓＰＬＡ２阻害作用を有する化合物
AU8531101A (en) *	2000-08-29	2002-03-13	Nobex Corp	Immunoregulatory compounds and derivatives and methods of treating diseases therewith
TWI314457B (de) *	2001-03-19	2009-09-11	Shionogi & Co
US8048924B2 (en) *	2001-08-29	2011-11-01	Biocon Limited	Methods and compositions employing 4-aminophenylacetic acid compounds
US7825132B2 (en)	2002-08-23	2010-11-02	Novartis Vaccines And Diagnostics, Inc.	Inhibition of FGFR3 and treatment of multiple myeloma
WO2004043389A2 (en) *	2002-11-13	2004-05-27	Chiron Corporation	Methods of treating cancer and related methods
PL2361620T3 (pl)	2004-02-06	2016-12-30		Zastosowanie aminosalicylanów w zespole jelita drażliwego z dominującą postacią biegunkową
CN1960731B (zh)	2004-02-20	2011-12-07	诺华疫苗和诊断公司	调节炎性和转移过程的方法
FR2867981B1 (fr)	2004-03-24	2008-10-31	Genevrier Sa Lab	Utilisation des chondroitine mono-et disulfates en therapeutique
WO2005117851A1 (en) *	2004-05-28	2005-12-15	Salix Pharmaceuticals, Inc.	Prevention, treatment, and amelioration of radiation induced enteritis
JP5009152B2 (ja) *	2004-05-28	2012-08-22	サリックスファーマシューティカルズ，インコーポレイテッド	放射線誘発性腸炎の予防、処置、および回復
DK1773767T3 (en)	2004-07-07	2016-03-21	Biocon Ltd	Synthesis of azo bound in immune regulatory relations
JP5344910B2 (ja)	2005-05-13	2013-11-20	ノバルティスアーゲー	薬剤耐性癌の処置方法
US7452872B2 (en) *	2005-08-24	2008-11-18	Salix Pharmaceuticals, Inc.	Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
EP2529729A1 (de)	2005-08-24	2012-12-05	Salix Pharmaceuticals, Inc.	Balsazidformulierungen und Herstellung davon
US8921344B2 (en) *	2006-11-03	2014-12-30	Salix Pharmaceuticals, Inc.	Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
RU2354384C1 (ru) *	2007-12-28	2009-05-10	Михаил Владимирович Кутушов	Применение органических красителей в качестве средства для лечения онкологических заболеваний
WO2010030781A2 (en) *	2008-09-10	2010-03-18	Numed International, Inc.	Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancer
EP2298321A1 (de)	2009-08-26	2011-03-23	Nordic Pharma	Neuartige pharmazeutische Zusammensetzungen zur Behandlung von IBD
MX358142B (es)	2010-04-26	2018-08-06	Salix Pharmaceuticals Ltd	Formulaciones y usos del derivado del ácido 2 - hidroxi -5 - fenilazobenzóico para el tratamiento de varones.
CN116173220A (zh) *	2022-03-02	2023-05-30	上海赛金生物医药有限公司	Ctla-4抑制剂和非类固醇抗炎药的抗癌联合治疗方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4412992A (en) *	1980-07-21	1983-11-01	Biorex Laboratories Limited	2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith
GB2080796B (en) *	1980-07-21	1983-10-12	Biorex Laboratories Ltd	2-hydroxy-5-phenylazobenzoic acid derivatives
NZ212419A (en) *	1984-06-25	1988-08-30	Mucan Diagnostics Pty Ltd	In vitro diagnostic test for detecting cancer cells producing mucin antigens
US5162202A (en) *	1989-12-12	1992-11-10	Shamsuddin Abulkalam M	Rectal mucus test and kit for detecting cancerous and precancerous conditions
US5498608A (en) *	1994-01-07	1996-03-12	Salix Pharmaceuticals	Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

1994
- 1994-01-07 US US08/178,578 patent/US5498608A/en not_active Expired - Lifetime
1995
- 1995-01-06 JP JP7518558A patent/JPH09510958A/ja not_active Withdrawn
- 1995-01-06 RO RO96-01403A patent/RO116525B1/ro unknown
- 1995-01-06 CA CA002180571A patent/CA2180571C/en not_active Expired - Fee Related
- 1995-01-06 EP EP95907293A patent/EP0738152B1/de not_active Expired - Lifetime
- 1995-01-06 AT AT95907293T patent/ATE308327T1/de active
- 1995-01-06 NZ NZ279062A patent/NZ279062A/xx unknown
- 1995-01-06 CN CN95191519A patent/CN1140994A/zh active Pending
- 1995-01-06 DK DK95907293T patent/DK0738152T3/da active
- 1995-01-06 WO PCT/US1995/000055 patent/WO1995018622A1/en active IP Right Grant
- 1995-01-06 AU AU15575/95A patent/AU691869B2/en not_active Expired
- 1995-01-06 DE DE69534564T patent/DE69534564T2/de not_active Expired - Lifetime
- 1995-01-06 HU HU9601846A patent/HUT74512A/hu unknown
- 1995-01-06 RU RU96117041/14A patent/RU2161487C2/ru active
- 1995-01-06 CZ CZ19961967A patent/CZ286460B6/cs not_active IP Right Cessation
- 1995-01-06 ES ES95907293T patent/ES2248796T3/es not_active Expired - Lifetime
1996
- 1996-07-03 FI FI962735A patent/FI962735A/fi unknown
- 1996-07-05 NO NO962841A patent/NO962841L/no unknown
2005
- 2005-03-14 JP JP2005072111A patent/JP4601466B2/ja not_active Expired - Lifetime
- 2005-03-14 JP JP2005115075A patent/JP2005320326A/ja not_active Withdrawn
2010
- 2010-07-12 JP JP2010157537A patent/JP2010235629A/ja active Pending

Also Published As

Publication number	Publication date
FI962735A0 (fi)	1996-07-03
CA2180571C (en)	2001-03-20
WO1995018622A1 (en)	1995-07-13
ES2248796T3 (es)	2006-03-16
CN1140994A (zh)	1997-01-22
US5498608A (en)	1996-03-12
HUT74512A (en)	1997-01-28
NZ279062A (en)	1999-11-29
EP0738152A1 (de)	1996-10-23
JP2010235629A (ja)	2010-10-21
HU9601846D0 (en)	1996-09-30
DE69534564D1 (de)	2005-12-08
DE69534564T2 (de)	2006-07-27
CA2180571A1 (en)	1995-07-13
FI962735A (fi)	1996-08-26
JPH09510958A (ja)	1997-11-04
CZ286460B6 (en)	2000-04-12
EP0738152B1 (de)	2005-11-02
CZ196796A3 (en)	1996-12-11
NO962841D0 (no)	1996-07-05
AU1557595A (en)	1995-08-01
JP2006096738A (ja)	2006-04-13
RU2161487C2 (ru)	2001-01-10
DK0738152T3 (da)	2006-01-30
EP0738152A4 (de)	2000-12-13
AU691869B2 (en)	1998-05-28
JP4601466B2 (ja)	2010-12-22
RO116525B1 (ro)	2001-03-30
JP2005320326A (ja)	2005-11-17
ATE308327T1 (de)	2005-11-15

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