NO954878L - Pyrrolderivater - Google Patents
PyrrolderivaterInfo
- Publication number
- NO954878L NO954878L NO954878A NO954878A NO954878L NO 954878 L NO954878 L NO 954878L NO 954878 A NO954878 A NO 954878A NO 954878 A NO954878 A NO 954878A NO 954878 L NO954878 L NO 954878L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- pyrrole
- inflammation
- pain
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
Det beskrives pyrrolderivater. Disse forbindelsene er anvendelige som antiinflammatoriske midler ved behandlingen av inflammasjon og smerte. Fremstillingen av disse forbindelsene, deres farmasøytisk akseptable salter samt farmasøytiske blandinger hvor disse forbindelsene inngår, er også beskrevet.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/347,915 US5622948A (en) | 1994-12-01 | 1994-12-01 | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
Publications (2)
Publication Number | Publication Date |
---|---|
NO954878D0 NO954878D0 (no) | 1995-11-30 |
NO954878L true NO954878L (no) | 1996-06-03 |
Family
ID=23365840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO954878A NO954878L (no) | 1994-12-01 | 1995-11-30 | Pyrrolderivater |
Country Status (19)
Country | Link |
---|---|
US (1) | US5622948A (no) |
EP (1) | EP0714895A1 (no) |
JP (1) | JPH08208639A (no) |
KR (1) | KR960022506A (no) |
CN (1) | CN1066726C (no) |
AR (1) | AR001771A1 (no) |
AU (1) | AU3906295A (no) |
BR (1) | BR9505610A (no) |
CA (1) | CA2163490A1 (no) |
CO (1) | CO4650183A1 (no) |
CZ (1) | CZ316995A3 (no) |
FI (1) | FI955783A (no) |
HU (1) | HUT75117A (no) |
IL (1) | IL116139A0 (no) |
MA (1) | MA23735A1 (no) |
NO (1) | NO954878L (no) |
PL (1) | PL311536A1 (no) |
TR (1) | TR199501528A1 (no) |
ZA (1) | ZA9510027B (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622948A (en) * | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
US6231888B1 (en) | 1996-01-18 | 2001-05-15 | Perio Products Ltd. | Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps |
CA2205757C (en) * | 1996-05-30 | 2006-01-24 | F. Hoffmann-La Roche Ag | Pyridazinone derivatives and their use as inhibitors of prostaglandin g/h synthase i and ii(cox i and ii) |
AU717602B2 (en) * | 1996-05-30 | 2000-03-30 | F. Hoffmann-La Roche Ag | Novel pyrrole derivatives |
WO1999010331A1 (en) * | 1997-08-22 | 1999-03-04 | Abbott Laboratories | Arylpyridazinones as prostaglandin endoperoxide h synthase biosynthesis inhibitors |
SK286972B6 (sk) * | 1997-08-22 | 2009-08-06 | Abbott Laboratories | Arylpyridazinóny ako inhibítory biosyntézy prostaglandín endoperoxid H syntázy, ich použitie a farmaceutická kompozícia s ich obsahom |
US6307047B1 (en) | 1997-08-22 | 2001-10-23 | Abbott Laboratories | Prostaglandin endoperoxide H synthase biosynthesis inhibitors |
US6525053B1 (en) | 1997-08-22 | 2003-02-25 | Abbott Laboratories | Prostaglandin endoperoxide H synthase biosynthesis inhibitors |
US6054453A (en) * | 1997-10-27 | 2000-04-25 | Redd's Research Foundation | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them |
US6531152B1 (en) | 1998-09-30 | 2003-03-11 | Dexcel Pharma Technologies Ltd. | Immediate release gastrointestinal drug delivery system |
SK286806B6 (sk) * | 1998-10-27 | 2009-05-07 | Abbott Laboratories | Pyridazinónové zlúčeniny ako inhibítory cyklooxygenázy, farmaceutická kompozícia s ich obsahom a ich použitie |
US6632451B2 (en) | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
WO2004006836A2 (en) * | 2002-07-11 | 2004-01-22 | Merck & Co., Inc. | Treatment of neuropathic pain with 6h-pyrrolo[3,4-d]pyridazine compounds |
EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
GB0610680D0 (en) * | 2006-05-31 | 2006-07-12 | Istituto Di Ricerche D Biolog | Therapeutic compounds |
EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
CN101855221B (zh) * | 2007-11-15 | 2013-10-30 | P.安杰莱蒂分子生物学研究所 | 作为parp抑制剂的哒嗪酮衍生物 |
NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
EP2527335B1 (en) | 2011-04-26 | 2013-09-18 | King Saud University | Triazole compounds as anti-inflammatory agents |
KR102233456B1 (ko) | 2017-05-31 | 2021-03-29 | 주식회사 대웅제약 | 4-메톡시피롤 유도체의 중간체 제조 방법 |
KR102233455B1 (ko) | 2017-06-21 | 2021-03-29 | 주식회사 대웅제약 | 4-메톡시피롤 유도체의 중간체 제조 방법 |
WO2022159980A1 (en) * | 2021-01-25 | 2022-07-28 | Athos Therapeutics, Inc. | Pharmaceutical compounds and methods of making and using the same |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2316942A (en) * | 1937-12-27 | 1943-04-20 | Schlumberger Well Surv Corp | Apparatus for measuring temperatures in boreholes |
US3586681A (en) * | 1967-11-02 | 1971-06-22 | Sandoz Ag | 1,4,5,6-tetrahydropyridazines |
US3726978A (en) * | 1967-11-02 | 1973-04-10 | Sandoz Ag | Tetrahydropyridazines and pyridazinones as anti-inflammatory agents |
US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
US4048191A (en) * | 1975-06-27 | 1977-09-13 | Mcneil Laboratories, Incorporated | Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds |
US4089969A (en) * | 1976-07-14 | 1978-05-16 | Syntex (U.S.A.) Inc. | 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof |
JPS539788A (en) * | 1976-07-14 | 1978-01-28 | Syntex Inc | 55aloyll1*22dihydroo3hh pyroro *1*22a* pyroll11 carboxylic acid derivative |
US4247551A (en) * | 1979-09-17 | 1981-01-27 | Gruppo Lepetit S.P.A. | N-Pyrrolyl-pyridazineamines and their use as antihypertensive agents |
US4347187A (en) * | 1980-10-20 | 1982-08-31 | Syntex (U.S.A.) Inc. | Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein |
IT1150070B (it) * | 1980-12-22 | 1986-12-10 | Lepetit Spa | Procedimento per preparare derivati n-pirrolipiridazinamminici |
AU8509882A (en) * | 1981-06-30 | 1983-01-06 | Merck & Co., Inc. | Tricyclic derivatives of substituted pyrrole acids |
WO1983000863A1 (en) * | 1981-09-11 | 1983-03-17 | Diamond Shamrock Corp | Antiinflammatory and analgetic 4-pyridylpyridazin(2h)-3-ones |
US4816454A (en) * | 1984-09-21 | 1989-03-28 | Cassella Aktiengesellschaft | 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use |
GB8501372D0 (en) * | 1985-01-18 | 1985-02-20 | Smith Kline French Lab | Chemical compounds |
US5086052A (en) * | 1987-07-17 | 1992-02-04 | Abbott Laboratories | Substituted 1,4,5,6-tetrahydro-2H-pyridazin-3-one and -3-thione compounds having lipoxygenase inhibitory activity |
US4992441A (en) * | 1987-10-14 | 1991-02-12 | Mcneilab, Inc. | 1-[[5-[[4-substituted-1-piperazinyl]methyl]-pyrrol-2-yl or furan-2-yl]methyl-2-piperidinones useful in treating schizophrenia |
IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
WO1994006919A2 (en) * | 1992-09-22 | 1994-03-31 | University Of Rochester | Stably-transformed mammalian cells expressing a regulated, inflammatory cyclooxygenase |
US5543297A (en) * | 1992-12-22 | 1996-08-06 | Merck Frosst Canada, Inc. | Human cyclooxygenase-2 cDNA and assays for evaluating cyclooxygenase-2 activity |
US5332736A (en) * | 1993-11-01 | 1994-07-26 | Ortho Pharmaceutical Corporation | Anti-convulsant aroyl aminoacylpyrroles |
US5622948A (en) * | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
KR102081455B1 (ko) * | 2017-06-09 | 2020-04-28 | 선상규 | 다중브러시를 이용한 직류발전장치 |
-
1994
- 1994-12-01 US US08/347,915 patent/US5622948A/en not_active Expired - Fee Related
-
1995
- 1995-11-20 EP EP95118227A patent/EP0714895A1/en not_active Withdrawn
- 1995-11-22 CA CA002163490A patent/CA2163490A1/en not_active Abandoned
- 1995-11-24 ZA ZA9510027A patent/ZA9510027B/xx unknown
- 1995-11-24 AU AU39062/95A patent/AU3906295A/en not_active Abandoned
- 1995-11-27 IL IL11613995A patent/IL116139A0/xx unknown
- 1995-11-27 HU HU9503384A patent/HUT75117A/hu unknown
- 1995-11-29 CZ CZ953169A patent/CZ316995A3/cs unknown
- 1995-11-30 CN CN95120375A patent/CN1066726C/zh not_active Expired - Fee Related
- 1995-11-30 PL PL95311536A patent/PL311536A1/xx unknown
- 1995-11-30 NO NO954878A patent/NO954878L/no unknown
- 1995-11-30 CO CO95056926A patent/CO4650183A1/es unknown
- 1995-11-30 KR KR1019950045751A patent/KR960022506A/ko not_active Application Discontinuation
- 1995-11-30 AR AR33445395A patent/AR001771A1/es unknown
- 1995-12-01 MA MA24084A patent/MA23735A1/fr unknown
- 1995-12-01 JP JP7313916A patent/JPH08208639A/ja active Pending
- 1995-12-01 FI FI955783A patent/FI955783A/fi unknown
- 1995-12-01 TR TR95/01528A patent/TR199501528A1/xx unknown
- 1995-12-01 BR BR9505610A patent/BR9505610A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AR001771A1 (es) | 1997-12-10 |
HUT75117A (en) | 1997-04-28 |
CO4650183A1 (es) | 1998-09-03 |
US5622948A (en) | 1997-04-22 |
FI955783A (fi) | 1996-06-02 |
CA2163490A1 (en) | 1996-06-02 |
KR960022506A (ko) | 1996-07-18 |
EP0714895A1 (en) | 1996-06-05 |
IL116139A0 (en) | 1996-01-31 |
ZA9510027B (en) | 1996-06-03 |
HU9503384D0 (en) | 1996-01-29 |
NO954878D0 (no) | 1995-11-30 |
MA23735A1 (fr) | 1996-07-01 |
BR9505610A (pt) | 1997-09-16 |
TR199501528A1 (tr) | 1996-11-21 |
AU3906295A (en) | 1996-06-06 |
FI955783A0 (fi) | 1995-12-01 |
CN1066726C (zh) | 2001-06-06 |
PL311536A1 (en) | 1996-06-10 |
JPH08208639A (ja) | 1996-08-13 |
CZ316995A3 (en) | 1996-06-12 |
CN1132206A (zh) | 1996-10-02 |
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