NO952199D0 - Antiallergic imidazo [1,2-aÅ (pyrrolo, thieno or furano) - [2,3-dazazepine derivatives - Google Patents
Antiallergic imidazo [1,2-aÅ (pyrrolo, thieno or furano) - [2,3-dazazepine derivativesInfo
- Publication number
- NO952199D0 NO952199D0 NO952199A NO952199A NO952199D0 NO 952199 D0 NO952199 D0 NO 952199D0 NO 952199 A NO952199 A NO 952199A NO 952199 A NO952199 A NO 952199A NO 952199 D0 NO952199 D0 NO 952199D0
- Authority
- NO
- Norway
- Prior art keywords
- 4alkyl
- hydroxycarbonyl
- substituted
- pct
- represents hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PCT No. PCT/EP93/03321 Sec. 371 Date May 8, 1995 Sec. 102(e) Date May 8, 1995 PCT Filed Nov. 25, 1993 PCT Pub. No. WO94/13680 PCT Pub. Date Jun. 23, 1994Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepines of formula <IMAGE> (I) the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein each of the dotted lines independently represents an optional bond; R1 represents hydrogen, C1-4alkyl, halo, ethenyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, hydroxyC1-4alkyl, formyl, hydroxycarbonyl or hydroxycarbonylC1-4alkyl; R2 represents hydrogen, C1-4alkyl, ethenyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, C1-4alkyl substituted with hydroxycarbonyl or C1-4alkyloxycarbonyl, hydroxyC1-4alkyl, formyl or hydroxycarbonyl; R3 represents hydrogen, C1-4alkyl, hydroxyC1-4alkyl, phenyl or halo; X represents O, S or NR4; L represents hydrogen; C1-6alkyl; substituted C1-6alkyl; C3-6alkenyl; C3-6alkenyl substituted with aryl; or a radical of formula-Alk-Y-Het1 (a-1), -Alk-NH-CO-Het2 (a-2) or -Alk-Het3 (a-3). Compositions comprising said compounds, processes of preparing the same and intermediates in the preparation thereof.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92203778 | 1992-12-04 | ||
PCT/EP1993/003321 WO1994013680A1 (en) | 1992-12-04 | 1993-11-25 | ANTIALLERGIC IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[2,3-d]AZEPINE DERIVATIVES |
Publications (3)
Publication Number | Publication Date |
---|---|
NO952199D0 true NO952199D0 (en) | 1995-06-02 |
NO952199L NO952199L (en) | 1995-08-04 |
NO311523B1 NO311523B1 (en) | 2001-12-03 |
Family
ID=8211106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19952199A NO311523B1 (en) | 1992-12-04 | 1995-06-02 | Antiallergic imidazo [1,2-a] (pyrrolo, thieno or furano) - [2,3-d] azepine derivatives |
Country Status (16)
Country | Link |
---|---|
US (1) | US5629308A (en) |
EP (1) | EP0672047B1 (en) |
JP (1) | JP3503064B2 (en) |
KR (1) | KR100251295B1 (en) |
AT (1) | ATE239023T1 (en) |
AU (1) | AU676702B2 (en) |
CA (1) | CA2150805C (en) |
DE (1) | DE69332929T2 (en) |
ES (1) | ES2199224T3 (en) |
FI (1) | FI952723A0 (en) |
HU (1) | HU223466B1 (en) |
NO (1) | NO311523B1 (en) |
NZ (1) | NZ258552A (en) |
PL (1) | PL176235B1 (en) |
RU (1) | RU2134269C1 (en) |
WO (1) | WO1994013680A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69328976T2 (en) * | 1992-12-04 | 2001-02-15 | Janssen Pharmaceutica Nv | ANTIALLERGIC TRIAZOLO (PYRROLO, THIENO OR FURANO) AZEPINE DERIVATIVES |
NZ258551A (en) * | 1992-12-04 | 1996-06-25 | Janssen Pharmaceutica Nv | Triazolobenzazepine compounds; includes a process for preparing the compounds and pharmaceutical compositions containing such a compound |
FR2735474B1 (en) * | 1995-06-13 | 1997-08-08 | Roussel Uclaf | ZILPATEROL HYDROCHLORIDE IN A PARTICULAR CRYSTALLIZED FORM, ITS PREPARATION PROCESS AND THE INTERMEDIATE PRODUCTS USED |
TW527186B (en) | 1996-03-19 | 2003-04-11 | Janssen Pharmaceutica Nv | Fused imidazole derivatives as multidrug resistance modulators |
WO1999013871A2 (en) * | 1997-09-18 | 1999-03-25 | Janssen Pharmaceutica N.V. | Fused imidazole derivatives for improving oral bioavailability of pharmaceutical agents |
WO2002100862A2 (en) | 2001-06-12 | 2002-12-19 | Janssen Pharmaceutica N.V. | Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine |
WO2011082269A2 (en) * | 2009-12-30 | 2011-07-07 | Arqule, Inc. | Substituted benzo-pyrimido-tetrazolo-diazepine compounds |
MX2017002610A (en) | 2014-08-29 | 2017-10-11 | Tes Pharma S R L | INHIBITORS OF A-AMINO-ß-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69110685T2 (en) * | 1990-10-10 | 1995-11-09 | Schering Corp | SUBSTITUTED IMIDAZOBENZAZEPINE AND IMIDAZOPYRIDOAZEPINE. |
IL101851A (en) * | 1991-06-13 | 1996-05-14 | Janssen Pharmaceutica Nv | 10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor |
-
1993
- 1993-11-25 AU AU56279/94A patent/AU676702B2/en not_active Ceased
- 1993-11-25 JP JP51372194A patent/JP3503064B2/en not_active Expired - Fee Related
- 1993-11-25 CA CA002150805A patent/CA2150805C/en not_active Expired - Fee Related
- 1993-11-25 NZ NZ258552A patent/NZ258552A/en unknown
- 1993-11-25 ES ES94901887T patent/ES2199224T3/en not_active Expired - Lifetime
- 1993-11-25 PL PL93309254A patent/PL176235B1/en not_active IP Right Cessation
- 1993-11-25 EP EP94901887A patent/EP0672047B1/en not_active Expired - Lifetime
- 1993-11-25 DE DE69332929T patent/DE69332929T2/en not_active Expired - Fee Related
- 1993-11-25 HU HU9501620A patent/HU223466B1/en not_active IP Right Cessation
- 1993-11-25 RU RU95114527A patent/RU2134269C1/en not_active IP Right Cessation
- 1993-11-25 US US08/433,386 patent/US5629308A/en not_active Expired - Fee Related
- 1993-11-25 AT AT94901887T patent/ATE239023T1/en not_active IP Right Cessation
- 1993-11-25 KR KR1019950702171A patent/KR100251295B1/en not_active IP Right Cessation
- 1993-11-25 WO PCT/EP1993/003321 patent/WO1994013680A1/en active IP Right Grant
-
1995
- 1995-06-02 FI FI952723A patent/FI952723A0/en unknown
- 1995-06-02 NO NO19952199A patent/NO311523B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
US5629308A (en) | 1997-05-13 |
FI952723A (en) | 1995-06-02 |
FI952723A0 (en) | 1995-06-02 |
DE69332929T2 (en) | 2004-02-26 |
WO1994013680A1 (en) | 1994-06-23 |
CA2150805A1 (en) | 1994-06-23 |
JPH08503953A (en) | 1996-04-30 |
CA2150805C (en) | 2006-08-15 |
ATE239023T1 (en) | 2003-05-15 |
NO952199L (en) | 1995-08-04 |
EP0672047A1 (en) | 1995-09-20 |
PL309254A1 (en) | 1995-10-02 |
RU2134269C1 (en) | 1999-08-10 |
PL176235B1 (en) | 1999-05-31 |
JP3503064B2 (en) | 2004-03-02 |
ES2199224T3 (en) | 2004-02-16 |
DE69332929D1 (en) | 2003-06-05 |
EP0672047B1 (en) | 2003-05-02 |
NZ258552A (en) | 1996-07-26 |
AU5627994A (en) | 1994-07-04 |
AU676702B2 (en) | 1997-03-20 |
HUT71807A (en) | 1996-02-28 |
RU95114527A (en) | 1997-06-10 |
HU9501620D0 (en) | 1995-08-28 |
KR100251295B1 (en) | 2000-05-01 |
NO311523B1 (en) | 2001-12-03 |
HU223466B1 (en) | 2004-07-28 |
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