NO945020L - Self-stabilizing oligonucleotides as therapeutic agents - Google Patents
Self-stabilizing oligonucleotides as therapeutic agentsInfo
- Publication number
- NO945020L NO945020L NO945020A NO945020A NO945020L NO 945020 L NO945020 L NO 945020L NO 945020 A NO945020 A NO 945020A NO 945020 A NO945020 A NO 945020A NO 945020 L NO945020 L NO 945020L
- Authority
- NO
- Norway
- Prior art keywords
- self
- oligonucleotides
- therapeutic agents
- stabilizing oligonucleotides
- nucleic acid
- Prior art date
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Forbedrede antisens oligonukleotider som er reslstente for nukleolytlske degradering er beskrevet. Silke oligonukleotider blir betegnet som selv-stablllserende oligonukleotder og omfatter to regioner: en mål- hybrldlserende region som har en nukleotldsekvens som er komplementær med en nuklelnsyresekvens som er fra et virus, en patogen organisme eller et cellulært gen; og en selv-komplementær region som har en ollgonukleotld- sekvens som er komplementær med en nuklelnsyresekvens som er Innenfor det selv-stablllserte ollgonukleotldet.Enhanced antigen oligonucleotides that are resistant to nucleolytic degradation are described. Silk oligonucleotides are termed self-stabilizing oligonucleotides and comprise two regions: a target hybridizing region having a nucleotide sequence complementary to a nucleic acid sequence that is from a virus, a pathogenic organism, or a cellular gene; and a self-complementary region having an oligonucleotide sequence complementary to a nucleic acid sequence which is within the self-stabilized oligonucleotide.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90906992A | 1992-07-02 | 1992-07-02 | |
PCT/US1993/006326 WO1994001550A1 (en) | 1992-07-02 | 1993-07-02 | Self-stabilized oligonucleotides as therapeutic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
NO945020D0 NO945020D0 (en) | 1994-12-23 |
NO945020L true NO945020L (en) | 1995-02-28 |
Family
ID=26786853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO945020A NO945020L (en) | 1992-07-02 | 1994-12-23 | Self-stabilizing oligonucleotides as therapeutic agents |
Country Status (1)
Country | Link |
---|---|
NO (1) | NO945020L (en) |
-
1994
- 1994-12-23 NO NO945020A patent/NO945020L/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO945020D0 (en) | 1994-12-23 |
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