NO942551L - Humanproteaseinhibitorvariant av Kunitz-type - Google Patents
Humanproteaseinhibitorvariant av Kunitz-typeInfo
- Publication number
- NO942551L NO942551L NO942551A NO942551A NO942551L NO 942551 L NO942551 L NO 942551L NO 942551 A NO942551 A NO 942551A NO 942551 A NO942551 A NO 942551A NO 942551 L NO942551 L NO 942551L
- Authority
- NO
- Norway
- Prior art keywords
- amino acid
- protease inhibitor
- variant
- type human
- naturally occurring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8114—Kunitz type inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK9200004 | 1992-01-07 | ||
PCT/DK1993/000003 WO1993014120A1 (en) | 1992-01-07 | 1993-01-07 | A human kunitz-type protease inhibitor variant |
Publications (2)
Publication Number | Publication Date |
---|---|
NO942551D0 NO942551D0 (no) | 1994-07-06 |
NO942551L true NO942551L (no) | 1994-09-07 |
Family
ID=8153774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO942551A NO942551L (no) | 1992-01-07 | 1994-07-06 | Humanproteaseinhibitorvariant av Kunitz-type |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0621870B1 (ru) |
JP (1) | JPH07506241A (ru) |
AT (1) | ATE152735T1 (ru) |
AU (1) | AU675925B2 (ru) |
CA (1) | CA2127250A1 (ru) |
CZ (1) | CZ164594A3 (ru) |
DE (1) | DE69310499D1 (ru) |
FI (1) | FI943232A0 (ru) |
HU (1) | HUT70294A (ru) |
IL (1) | IL104326A0 (ru) |
NO (1) | NO942551L (ru) |
NZ (1) | NZ246568A (ru) |
RU (1) | RU94045952A (ru) |
WO (1) | WO1993014120A1 (ru) |
ZA (1) | ZA9397B (ru) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE529444T1 (de) | 1994-01-11 | 2011-11-15 | Dyax Corp | Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten |
ATE275583T1 (de) * | 1994-01-11 | 2004-09-15 | Dyax Corp | KALLIKREINHEMMENDE ßKUNITZ-DOMÄNEß-PROTEINE UND DERIVATEN DAVON |
US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
US5795954A (en) * | 1994-03-04 | 1998-08-18 | Genentech, Inc. | Factor VIIa inhibitors from Kunitz domain proteins |
US5589359A (en) | 1994-08-05 | 1996-12-31 | Chiron Corporation | Chimeric proteins |
ATE226249T1 (de) * | 1994-08-05 | 2002-11-15 | Chiron Corp | Herstellung des inhibitors fuer die komplexbildung des gewebefaktors |
ZA963619B (en) | 1995-05-08 | 1996-11-22 | Scios Inc | Protease inhibitor peptides |
CA2220497A1 (en) * | 1995-05-08 | 1996-11-14 | Scios, Inc. | Kunitz type protease inhibitors |
US5780265A (en) * | 1995-06-05 | 1998-07-14 | Genentech, Inc. | Kunitz type plasma kallikrein inhibitors |
US5786328A (en) * | 1995-06-05 | 1998-07-28 | Genentech, Inc. | Use of kunitz type plasma kallikrein inhibitors |
US6242414B1 (en) | 1995-06-07 | 2001-06-05 | Chiron Corporation | Regulation of cytokine synthesis and release |
BR9708021A (pt) | 1996-03-11 | 1999-07-27 | Bayer Ag | Proteína substancialmente purificada composição farmacêutica sequência de ácido nucleico isolada vetor de express o de protéina auto-replicante e processos para inibir a atividade de protéinas de serina tratar uma condição e preparar um medicamento de uma proteína |
US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
CA2488558C (en) | 2002-06-07 | 2013-08-20 | Dyax Corp. | Prevention and reduction of blood loss |
DK2386310T3 (en) * | 2002-08-28 | 2019-02-25 | Dyax Corp | Methods of preserving organs and tissues |
US6989369B2 (en) | 2003-02-07 | 2006-01-24 | Dyax Corp. | Kunitz domain peptides |
WO2005021557A2 (en) | 2003-08-29 | 2005-03-10 | Dyax Corp. | Poly-pegylated protease inhibitors |
US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
DK1976985T3 (da) * | 2005-12-29 | 2013-10-21 | Univ California | Fremgangsmåder og præparater relateret til mutant Kunitz-domæne I af TFPI-2 |
US7276480B1 (en) | 2005-12-30 | 2007-10-02 | Dyax Corp. | Prevention and reduction of blood loss |
AU2009327338B2 (en) | 2008-12-19 | 2015-07-02 | Takeda Pharmaceutical Company Limited | TFPI inhibitors and methods of use |
WO2010080833A1 (en) | 2009-01-06 | 2010-07-15 | Dyax Corp. | Treatment of mucositis with kallikrein inhibitors |
CN101798346B (zh) * | 2009-02-06 | 2013-05-29 | 复旦大学 | 一种酵母表达的长效重组人组织因子途径抑制物 |
SI2521568T1 (sl) | 2010-01-06 | 2019-01-31 | Dyax Corp. | Proteini, ki vežejo plazemski kalikrein |
NZ603028A (en) | 2010-03-19 | 2014-11-28 | Baxter Healthcare Sa | Tfpi inhibitors and methods of use |
IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | KALLIKREIN PLASMA BINDING PROTEINS |
NZ724133A (en) | 2012-03-21 | 2020-07-31 | Baxalta Inc | Tfpi inhibitors and methods of use |
JP7003354B2 (ja) | 2015-12-11 | 2022-03-04 | 武田薬品工業株式会社 | 遺伝性血管性浮腫の発作を治療するための血漿カリクレイン阻害薬およびその用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5106833A (en) * | 1987-07-23 | 1992-04-21 | Washington University | Coagulation inhibitors |
DK408089D0 (da) * | 1989-08-18 | 1989-08-18 | Novo Nordisk As | Proteiner |
-
1993
- 1993-01-06 IL IL104326A patent/IL104326A0/xx unknown
- 1993-01-07 CA CA002127250A patent/CA2127250A1/en not_active Abandoned
- 1993-01-07 JP JP5511991A patent/JPH07506241A/ja active Pending
- 1993-01-07 CZ CZ941645A patent/CZ164594A3/cs unknown
- 1993-01-07 AU AU33458/93A patent/AU675925B2/en not_active Ceased
- 1993-01-07 ZA ZA9397A patent/ZA9397B/xx unknown
- 1993-01-07 EP EP93902104A patent/EP0621870B1/en not_active Expired - Lifetime
- 1993-01-07 WO PCT/DK1993/000003 patent/WO1993014120A1/en not_active Application Discontinuation
- 1993-01-07 AT AT93902104T patent/ATE152735T1/de not_active IP Right Cessation
- 1993-01-07 HU HU9401992A patent/HUT70294A/hu unknown
- 1993-01-07 RU RU94045952/13A patent/RU94045952A/ru unknown
- 1993-01-07 NZ NZ246568A patent/NZ246568A/en unknown
- 1993-01-07 DE DE69310499T patent/DE69310499D1/de not_active Expired - Lifetime
-
1994
- 1994-07-06 NO NO942551A patent/NO942551L/no unknown
- 1994-07-06 FI FI943232A patent/FI943232A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2127250A1 (en) | 1993-07-22 |
JPH07506241A (ja) | 1995-07-13 |
AU675925B2 (en) | 1997-02-27 |
DE69310499D1 (de) | 1997-06-12 |
CZ164594A3 (en) | 1994-12-15 |
WO1993014120A1 (en) | 1993-07-22 |
FI943232A (fi) | 1994-07-06 |
EP0621870B1 (en) | 1997-05-07 |
HU9401992D0 (en) | 1994-09-28 |
HUT70294A (en) | 1995-09-28 |
FI943232A0 (fi) | 1994-07-06 |
RU94045952A (ru) | 1996-10-10 |
ZA9397B (en) | 1993-08-10 |
IL104326A0 (en) | 1993-05-13 |
EP0621870A1 (en) | 1994-11-02 |
AU3345893A (en) | 1993-08-03 |
NO942551D0 (no) | 1994-07-06 |
ATE152735T1 (de) | 1997-05-15 |
NZ246568A (en) | 1996-02-27 |
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