NO940736L - DNA sekvenser som koder for gelonin polypeptid - Google Patents

DNA sekvenser som koder for gelonin polypeptid

Info

Publication number
NO940736L
NO940736L NO940736A NO940736A NO940736L NO 940736 L NO940736 L NO 940736L NO 940736 A NO940736 A NO 940736A NO 940736 A NO940736 A NO 940736A NO 940736 L NO940736 L NO 940736L
Authority
NO
Norway
Prior art keywords
dna sequences
gelonin
sequences encoding
synthetic gene
encoding gelonin
Prior art date
Application number
NO940736A
Other languages
English (en)
Other versions
NO940736D0 (no
NO317659B1 (no
Inventor
Michael G Rosenblum
Kenneth L Beattie
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of NO940736D0 publication Critical patent/NO940736D0/no
Publication of NO940736L publication Critical patent/NO940736L/no
Publication of NO317659B1 publication Critical patent/NO317659B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A61K47/6819—Plant toxins
    • A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
NO19940736A 1991-09-06 1994-03-03 Syntetisk DNA som koder for gelonin-polypeptid, fremgangsmate for fremstilling av dette, samt en vertscelle som inneholder en ekspresjonsvektor omfattende nevnte syntetiske DNA NO317659B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75594991A 1991-09-06 1991-09-06
PCT/US1992/007066 WO1993005168A1 (en) 1991-09-06 1992-08-21 Dna sequences encoding gelonin polypeptide

Publications (3)

Publication Number Publication Date
NO940736D0 NO940736D0 (no) 1994-03-03
NO940736L true NO940736L (no) 1994-03-03
NO317659B1 NO317659B1 (no) 2004-11-29

Family

ID=25041367

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19940736A NO317659B1 (no) 1991-09-06 1994-03-03 Syntetisk DNA som koder for gelonin-polypeptid, fremgangsmate for fremstilling av dette, samt en vertscelle som inneholder en ekspresjonsvektor omfattende nevnte syntetiske DNA

Country Status (18)

Country Link
US (1) US5624827A (no)
EP (1) EP0602144B1 (no)
JP (1) JPH06510431A (no)
KR (1) KR100270195B1 (no)
CN (1) CN1047402C (no)
AT (1) ATE173023T1 (no)
AU (1) AU679427B2 (no)
CA (1) CA2115049C (no)
DE (1) DE69227519T2 (no)
DK (1) DK0602144T3 (no)
ES (1) ES2123008T3 (no)
FI (1) FI113547B (no)
IL (1) IL103057A (no)
NO (1) NO317659B1 (no)
NZ (1) NZ244220A (no)
RU (1) RU2142015C1 (no)
WO (1) WO1993005168A1 (no)
ZA (1) ZA926705B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5317009A (en) * 1991-08-26 1994-05-31 New York University Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof
US5837491A (en) * 1991-11-04 1998-11-17 Xoma Corporation Polynucleotides encoding gelonin sequences
US6146850A (en) * 1991-11-04 2000-11-14 Xoma Corporation Proteins encoding gelonin sequences
US5621083A (en) * 1991-11-04 1997-04-15 Xoma Corporation Immunotoxins comprising ribosome-inactivating proteins
US5869619A (en) * 1991-12-13 1999-02-09 Xoma Corporation Modified antibody variable domains
JP4157160B2 (ja) * 1991-12-13 2008-09-24 ゾーマ テクノロジー リミテッド 改変抗体可変領域の調製のための方法
CA2162689C (en) * 1993-05-12 2000-07-18 Marc D. Better Immunotoxins comprising gelonin and an antibody
US20030166169A1 (en) * 1998-01-16 2003-09-04 Padgett Hal S. Method for constructing viral nucleic acids in a cell-free manner
ZA200305980B (en) 2001-02-12 2007-01-31 Res Dev Foundation Modified proteins, designer toxins, and methods of making thereof
EP1414471B1 (en) * 2001-07-17 2012-06-13 Research Development Foundation Therapeutic agents comprising pro-apoptotic proteins
AU2003275985A1 (en) * 2002-06-12 2003-12-31 Research Development Foundation Immunotoxin as a therapeutic agent and uses thereof
CA2502367C (en) 2002-10-16 2013-12-10 Euro-Celtique S.A. Antibodies that bind cell-associated ca 125/o772p and methods of use thereof
RU2393874C2 (ru) * 2005-02-01 2010-07-10 Рисерч Дивелопмент Фаундейшн Полипептиды с направленным действием
KR101224828B1 (ko) * 2009-05-14 2013-01-22 (주)바이오니아 ｓｉＲＮＡ 접합체 및 그 제조방법
US8759036B2 (en) * 2011-03-21 2014-06-24 Affymetrix, Inc. Methods for synthesizing pools of probes
US20130109596A1 (en) 2011-09-26 2013-05-02 Life Technologies Corporation High efficiency, small volume nucleic acid synthesis
EP4029937A1 (en) 2012-10-04 2022-07-20 Research Development Foundation Serine protease molecules and therapies
US10563240B2 (en) 2013-03-14 2020-02-18 Life Technologies Corporation High efficiency, small volume nucleic acid synthesis
CA3147259A1 (en) 2014-12-09 2016-06-16 Life Technologies Corporation High efficiency, small volume nucleic acid synthesis
EP3359669B1 (en) 2015-10-06 2020-05-13 Pierce Biotechnology, Inc. Devices and methods for producing proteins
US20210147830A1 (en) 2018-06-29 2021-05-20 Thermo Fisher Scientific Geneart Gmbh High throughput assembly of nucleic acid molecules
GB201905303D0 (en) 2019-04-15 2019-05-29 Thermo Fisher Scient Geneart Gmbh Multiplex assembly of nucleic acid molecules
US20240025939A1 (en) 2020-03-06 2024-01-25 Life Technologies Corporation High sequence fidelity nucleic acid synthesis and assembly
WO2024132094A1 (en) 2022-12-19 2024-06-27 Thermo Fisher Scientific Geneart Gmbh Retrieval of sequence-verified nucleic acid molecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888415A (en) * 1985-03-04 1989-12-19 Dana-Farber Cancer Institute, Inc. Gelonin immunotoxin
US5024947A (en) * 1987-07-24 1991-06-18 Cetus Corporation Serum free media for the growth on insect cells and expression of products thereby
US5290914A (en) * 1988-04-28 1994-03-01 Mycogen Corporation Hybrid diphtheria-B.t. pesticidal toxins
IE912716A1 (en) * 1990-08-14 1992-02-26 Res Dev Foundation Protein Structure of the Plant Toxin Gelonin

Also Published As

Publication number Publication date
EP0602144A4 (en) 1995-03-15
ES2123008T3 (es) 1999-01-01
KR100270195B1 (ko) 2001-03-02
CA2115049A1 (en) 1993-03-18
RU2142015C1 (ru) 1999-11-27
DE69227519T2 (de) 1999-06-02
CN1070227A (zh) 1993-03-24
JPH06510431A (ja) 1994-11-24
US5624827A (en) 1997-04-29
RU94034733A (ru) 1996-06-10
FI113547B (fi) 2004-05-14
DE69227519D1 (de) 1998-12-10
NZ244220A (en) 1994-12-22
FI941048A0 (fi) 1994-03-04
NO940736D0 (no) 1994-03-03
FI941048A (fi) 1994-03-04
CN1047402C (zh) 1999-12-15
CA2115049C (en) 2003-10-21
DK0602144T3 (da) 1999-07-19
WO1993005168A1 (en) 1993-03-18
ZA926705B (en) 1993-04-28
ATE173023T1 (de) 1998-11-15
EP0602144A1 (en) 1994-06-22
NO317659B1 (no) 2004-11-29
EP0602144B1 (en) 1998-11-04
IL103057A (en) 1999-09-22
IL103057A0 (en) 1993-02-21
AU2547692A (en) 1993-04-05
AU679427B2 (en) 1997-07-03

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