NO923533D0 - NEW 5-AMINO-4-HYDROXYE HEXIC ACID DERIVATIVES AS THERAPEUTICS - Google Patents

NEW 5-AMINO-4-HYDROXYE HEXIC ACID DERIVATIVES AS THERAPEUTICS

Info

Publication number
NO923533D0
NO923533D0 NO923533A NO923533A NO923533D0 NO 923533 D0 NO923533 D0 NO 923533D0 NO 923533 A NO923533 A NO 923533A NO 923533 A NO923533 A NO 923533A NO 923533 D0 NO923533 D0 NO 923533D0
Authority
NO
Norway
Prior art keywords
hydroxye
therapeutics
amino
new
acid derivatives
Prior art date
Application number
NO923533A
Other languages
Norwegian (no)
Other versions
NO923533L (en
Inventor
Marc Lang
Guido Bold
Alexander Faessler
Peter Schneider
Peter Van Hoogevest
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO923533D0 publication Critical patent/NO923533D0/en
Publication of NO923533L publication Critical patent/NO923533L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO92923533A 1991-09-12 1992-09-11 NEW 5-AMINO-4-HYDROXYE HEXIC ACID DERIVATIVES AS THERAPEUTICS NO923533L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH268991 1991-09-12
CH98092 1992-03-27
CH200792 1992-06-25

Publications (2)

Publication Number Publication Date
NO923533D0 true NO923533D0 (en) 1992-09-11
NO923533L NO923533L (en) 1993-03-15

Family

ID=27172572

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923533A NO923533L (en) 1991-09-12 1992-09-11 NEW 5-AMINO-4-HYDROXYE HEXIC ACID DERIVATIVES AS THERAPEUTICS

Country Status (15)

Country Link
EP (1) EP0532466A3 (en)
JP (1) JPH05230095A (en)
KR (1) KR930006050A (en)
AU (1) AU661018B2 (en)
CA (1) CA2077948A1 (en)
CZ (1) CZ280292A3 (en)
FI (1) FI924035A (en)
HU (1) HUT63632A (en)
IL (1) IL103126A (en)
MX (1) MX9205208A (en)
NO (1) NO923533L (en)
NZ (1) NZ244288A (en)
PL (1) PL169969B1 (en)
RU (1) RU2067585C1 (en)
SK (1) SK280292A3 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643878A (en) * 1991-09-12 1997-07-01 Ciba-Geigy Corporation 5-amino-4-hydroxyhexanoic acid derivatives
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
WO1993018006A1 (en) * 1992-03-11 1993-09-16 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
DE69333270T2 (en) 1992-03-11 2004-08-05 Narhex Ltd. AMINE DERIVATIVES OF OXO AND HYDROXY SUBSTITUTED CARBON HYDROGEN
TW217410B (en) * 1992-04-01 1993-12-11 Ciba Geigy
DE59303870D1 (en) 1992-12-23 1996-10-24 Ciba Geigy Ag Antiretroviral hydrazine derivatives
EP0618222A3 (en) * 1993-03-11 1997-01-02 Ciba Geigy Ag Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid.
EP0626178A1 (en) * 1993-05-17 1994-11-30 Ciba-Geigy Ag Use of inhibitors of HIV-protease for the treatment of tumorous diseases
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) * 1993-10-01 1996-09-24 Abbott Laboratories Pharmaceutical composition
IL111991A (en) * 1994-01-28 2000-07-26 Abbott Lab Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
WO1996016980A1 (en) * 1994-11-29 1996-06-06 Novartis Ag Morpholinoethylamide derivatives
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
US5840835A (en) * 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
US5817757A (en) * 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
WO1997016188A1 (en) * 1995-10-30 1997-05-09 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US6232333B1 (en) 1996-11-21 2001-05-15 Abbott Laboratories Pharmaceutical composition
WO2000044770A1 (en) * 1999-01-28 2000-08-03 Chugai Seiyaku Kabushiki Kaisha Substituted phenethylamine derivatives
US6455734B1 (en) * 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
KR100708221B1 (en) 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 Method for producing epoxide crystal
SI1248600T1 (en) 2000-01-19 2008-08-31 Abbott Lab Improved hiv protease inhibitors pharmaceutical formulations
US6506786B2 (en) 2001-02-13 2003-01-14 Pharmacor Inc. HIV protease inhibitors based on amino acid derivatives
NZ539727A (en) * 2002-11-01 2008-01-31 Viropharma Inc Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
ES2452718T3 (en) 2005-11-30 2014-04-02 Taimed Biologics, Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
CA2640435C (en) 2006-01-27 2011-11-01 Fibrogen, Inc. Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif)
BRPI0710527B8 (en) 2006-04-04 2021-05-25 Fibrogen Inc pyrrolo- and thiazolo-pyridine compounds and pharmaceutical composition comprising them
WO2008078200A2 (en) 2006-09-21 2008-07-03 Ambrilia Biopharma Inc. Protease inhibitors
US8927591B2 (en) 2008-11-14 2015-01-06 Fibrogen, Inc. Thiochromene derivatives as HIF hydroxylase inhibitors
JP6437456B2 (en) 2013-01-24 2018-12-12 フィブロジェン インコーポレイテッド Crystalline form of {[1-cyano-5- (4-chlorophenoxy) -4-hydroxy-isoquinoline-3-carbonyl] -amino} -acetic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126326A (en) * 1989-06-06 1992-06-30 Bio-Mega, Inc. Enzyme inhibiting peptide derivatives

Also Published As

Publication number Publication date
EP0532466A2 (en) 1993-03-17
CA2077948A1 (en) 1993-03-13
IL103126A (en) 1997-09-30
AU2288992A (en) 1993-03-18
NO923533L (en) 1993-03-15
NZ244288A (en) 1995-03-28
PL295905A1 (en) 1993-05-17
IL103126A0 (en) 1993-02-21
MX9205208A (en) 1993-03-01
FI924035A0 (en) 1992-09-09
HU9202925D0 (en) 1992-11-30
PL169969B1 (en) 1996-09-30
HUT63632A (en) 1993-09-28
CZ280292A3 (en) 1994-01-19
EP0532466A3 (en) 1993-06-16
RU2067585C1 (en) 1996-10-10
FI924035A (en) 1993-03-13
SK280292A3 (en) 1995-02-08
KR930006050A (en) 1993-04-20
JPH05230095A (en) 1993-09-07
AU661018B2 (en) 1995-07-13

Similar Documents

Publication Publication Date Title
NO923533D0 (en) NEW 5-AMINO-4-HYDROXYE HEXIC ACID DERIVATIVES AS THERAPEUTICS
MX9205145A (en) NEW DERIVATIVES HETEROCICLICOS.
ATE212630T1 (en) CRYSTALLINE OXATHIOLAND DERIVATIVES
DK0533268T3 (en) Benzanilide derivatives as 5HT-1D antagonists
NO941179D0 (en) Heteroberlamines as novel acetylcholinesterase inhibitors
ATE118767T1 (en) 3-SUBSTITUTED-2-OXINDOLE DERIVATIVES AS ANTI-INFLAMMATORY.
FI921994A (en) REDUCERING AV KLIBBIGA FOERORENINGAR I PAPPERSFRAMSTAELLNINGSPROCESSER, VID VILKA ANVAENDS RETURPAPPER
FI922973A (en) TOCOFEROLBLANDNING FOER ANVAENDNING SOM ANTIOXIDANT FOER KRUSMYNTOLJA I TUGGUMMI
FI940469A (en) Quinoline derivatives as immunostimulants
NO940144L (en) 2- (4-hydroxypiperidino) 1-alkanol derivatives as anti-chemical agents
NO930156L (en) NEW OKSAZOLYL DERIVATIVES
DK0509974T3 (en) New active compounds
NO921840D0 (en) SUBSTITUTED CARBOXYLIC ACID DERIVATIVES
FI925284A0 (en) INKAPSLADE PARTIKLAR ANVAENDBARA SOM KONTRASTMEDEL I KOMPOSITIONER OCH METODER, SOM ANVAENDS VID ULTRALJUD- OCH ROENTGENAVBILDNING
DE68913137D1 (en) Carboxylic acid derivatives.
NO923382D0 (en) NEW, THERAPEUTICALLY EFFECTIVE BENZOPYRAND DERIVATIVES
NO923508D0 (en) BICYCLIC CARBOXYLIC ACID DERIVATIVES
NO881535D0 (en) NEW SUBSTITUTED ANILIDE DERIVATIVES.
DK10190A (en) 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES
DE69122555D1 (en) 2,4-Dihydroxyadipic acid derivatives
ATE121078T1 (en) PROPENEIC ACID DERIVATIVES.
DK670589A (en) carboxylic acid derivatives
NO881899D0 (en) NEW 2-AMINOALKYL-4-BENZYL-1- (2H) -PHTHALAZION DERIVATIVES.
BG97094A (en) AMINO ACID DERIVATIVES
DE59105006D1 (en) Cyclohexane derivatives containing carboxyl groups.