NO903564D0 - Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropylamino)androst-5-en-3beta-ol-derivater. - Google Patents
Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropylamino)androst-5-en-3beta-ol-derivater.Info
- Publication number
- NO903564D0 NO903564D0 NO903564A NO903564A NO903564D0 NO 903564 D0 NO903564 D0 NO 903564D0 NO 903564 A NO903564 A NO 903564A NO 903564 A NO903564 A NO 903564A NO 903564 D0 NO903564 D0 NO 903564D0
- Authority
- NO
- Norway
- Prior art keywords
- androst
- cyclopropylamino
- substituted
- 17beta
- 3beta
- Prior art date
Links
- -1 CYCLOPROPYLAMINO Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- LYFPAZBMEUSVNA-UHFFFAOYSA-N (10R)-3c-Hydroxy-10r.13c-dimethyl-(8cH.9tH.14tH)-Delta5-tetradecahydro-1H-cyclopenta[a]phenanthren Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCCC1(C)CC2 LYFPAZBMEUSVNA-UHFFFAOYSA-N 0.000 abstract 1
- LYFPAZBMEUSVNA-DYKIIFRCSA-N (3s,8s,9s,10r,13s,14s)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-ol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 LYFPAZBMEUSVNA-DYKIIFRCSA-N 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 150000002466 imines Chemical class 0.000 abstract 1
- 230000003637 steroidlike Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/394,025 US4966898A (en) | 1989-08-15 | 1989-08-15 | 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO903564D0 true NO903564D0 (no) | 1990-08-14 |
| NO903564L NO903564L (no) | 1991-02-18 |
Family
ID=23557240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO90903564A NO903564L (no) | 1989-08-15 | 1990-08-14 | Fremgangsmaate for fremstilling av 4-substituerte 17beta-(cyklopropylamino)androst-5-en-3beta-ol-derivater. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4966898A (no) |
| EP (1) | EP0413270B1 (no) |
| JP (1) | JP2879703B2 (no) |
| KR (1) | KR910004649A (no) |
| CN (1) | CN1050196A (no) |
| AT (1) | ATE137761T1 (no) |
| AU (1) | AU628209B2 (no) |
| CA (1) | CA2023012C (no) |
| DD (1) | DD299650A5 (no) |
| DE (1) | DE69026881T2 (no) |
| ES (1) | ES2088928T3 (no) |
| FI (1) | FI95804C (no) |
| HU (1) | HUT55029A (no) |
| IE (1) | IE72516B1 (no) |
| IL (1) | IL95358A (no) |
| NO (1) | NO903564L (no) |
| NZ (1) | NZ234856A (no) |
| PH (1) | PH27098A (no) |
| PT (1) | PT94993B (no) |
| ZA (1) | ZA906308B (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4966897A (en) * | 1989-08-15 | 1990-10-30 | Merrell Dow Pharmaceuticals Inc. | 4-substituted 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
| JP2742331B2 (ja) * | 1992-03-31 | 1998-04-22 | ブリテイツシユ・テクノロジー・グループ・リミテツド | 癌治療に有用な１７位置換ステロイド |
| US5604213A (en) * | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
| TW369521B (en) * | 1993-09-17 | 1999-09-11 | Smithkline Beecham Corp | Androstenone derivative |
| US5541322A (en) * | 1994-10-14 | 1996-07-30 | Glaxo Wellcome Inc. | Synthesis of 6-azaandrostenones |
| US6365597B1 (en) | 1996-02-14 | 2002-04-02 | Aventis Pharmaceuticals Inc. | 4-aza steroids |
| AU2001276370B2 (en) * | 2000-06-09 | 2006-08-03 | Merial Limited | Process for the preparation of pesticidal compounds |
| MY134929A (en) | 2000-11-17 | 2008-01-31 | Takeda Pharmaceutical | Novel imidazole derivatives, production method thereof and use thereof |
| ATE502030T1 (de) | 2000-11-20 | 2011-04-15 | Takeda Pharmaceutical | Imidazolderivate, verfahren zu deren herstellung und deren verwendung |
| DE60139639D1 (de) | 2000-12-08 | 2009-10-01 | Takeda Pharmaceutical | Substituierte thiazolderivate mit 3-pyridylgruppen, verfahren zu deren herstellung und deren verwendung |
| US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
| UA105794C2 (uk) | 2009-06-26 | 2014-06-25 | Новартіс Аг | 1,3-ДИЗАМІЩЕНІ ПОХІДНІ ІМІДАЗОЛІДИН-2-ОНУ ЯК ІНГІБІТОРИ Cyp17 |
| JP2011098893A (ja) * | 2009-11-04 | 2011-05-19 | Sumitomo Chemical Co Ltd | テストステロンの生合成を抑制するための化合物の使用およびその化合物 |
| WO2012018948A2 (en) | 2010-08-04 | 2012-02-09 | Pellficure Pharmaceuticals, Inc. | Novel treatment of prostate carcinoma |
| JP2013537210A (ja) | 2010-09-16 | 2013-09-30 | ノバルティス アーゲー | １７α−ヒドロキシラーゼ／Ｃ１７，２０−リアーゼ阻害剤 |
| JP6002210B2 (ja) | 2011-04-28 | 2016-10-05 | ノバルティス アーゲー | １７α−ヒドロキシラーゼ／Ｃ１７，２０−リアーゼ阻害剤 |
| EP2968219B1 (en) | 2013-03-14 | 2019-04-24 | Pellficure Pharmaceuticals, Inc. | Novel therapy for prostate carcinoma |
| US10093620B2 (en) | 2014-09-12 | 2018-10-09 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
| BR112019001398A2 (pt) | 2016-07-29 | 2019-05-07 | Janssen Pharmaceutica Nv | métodos para tratamento de câncer de próstata |
| AU2017350690A1 (en) | 2016-10-24 | 2019-06-13 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3107254A (en) * | 1960-10-05 | 1963-10-15 | Upjohn Co | 17beta-dialkylamino-17-cyanosteroids and their 17alpha-alkyl, alkylene and alkyne derivatives |
| US3097200A (en) * | 1962-01-03 | 1963-07-09 | Syntex Corp | 17-aminoandrostanes |
| NL302932A (no) * | 1962-12-31 | |||
| ZA882717B (en) * | 1987-04-22 | 1988-10-17 | Merrell Dow Pharmaceuticals Inc. | 17beta-(cyclopropylamino)-androst-5-eb-3beta-ol and related compounds useful as c17-20 lyase inhibitors |
| US4966897A (en) * | 1989-08-15 | 1990-10-30 | Merrell Dow Pharmaceuticals Inc. | 4-substituted 17β-(cyclopropyloxy)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
-
1989
- 1989-08-15 US US07/394,025 patent/US4966898A/en not_active Expired - Fee Related
-
1990
- 1990-08-09 JP JP2209389A patent/JP2879703B2/ja not_active Expired - Fee Related
- 1990-08-09 AU AU60877/90A patent/AU628209B2/en not_active Ceased
- 1990-08-09 ZA ZA906308A patent/ZA906308B/xx unknown
- 1990-08-09 CA CA002023012A patent/CA2023012C/en not_active Expired - Fee Related
- 1990-08-10 AT AT90115391T patent/ATE137761T1/de not_active IP Right Cessation
- 1990-08-10 EP EP90115391A patent/EP0413270B1/en not_active Expired - Lifetime
- 1990-08-10 DE DE69026881T patent/DE69026881T2/de not_active Expired - Fee Related
- 1990-08-10 NZ NZ234856A patent/NZ234856A/en unknown
- 1990-08-10 ES ES90115391T patent/ES2088928T3/es not_active Expired - Lifetime
- 1990-08-13 IL IL9535890A patent/IL95358A/en not_active IP Right Cessation
- 1990-08-14 NO NO90903564A patent/NO903564L/no unknown
- 1990-08-14 PT PT94993A patent/PT94993B/pt not_active IP Right Cessation
- 1990-08-14 HU HU905004A patent/HUT55029A/hu unknown
- 1990-08-14 IE IE294290A patent/IE72516B1/en not_active IP Right Cessation
- 1990-08-14 KR KR1019900012533A patent/KR910004649A/ko not_active Application Discontinuation
- 1990-08-15 PH PH41034A patent/PH27098A/en unknown
- 1990-08-15 FI FI904035A patent/FI95804C/fi not_active IP Right Cessation
- 1990-08-15 DD DD90343476A patent/DD299650A5/de unknown
- 1990-08-15 CN CN90107580A patent/CN1050196A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU628209B2 (en) | 1992-09-10 |
| EP0413270B1 (en) | 1996-05-08 |
| FI95804C (fi) | 1996-03-25 |
| JP2879703B2 (ja) | 1999-04-05 |
| JPH0383998A (ja) | 1991-04-09 |
| PT94993B (pt) | 1997-07-31 |
| FI95804B (fi) | 1995-12-15 |
| HUT55029A (en) | 1991-04-29 |
| CA2023012C (en) | 2001-07-03 |
| HU905004D0 (en) | 1991-01-28 |
| EP0413270A3 (en) | 1992-05-20 |
| IE902942A1 (en) | 1991-02-27 |
| CA2023012A1 (en) | 1991-02-16 |
| PH27098A (en) | 1993-02-26 |
| US4966898A (en) | 1990-10-30 |
| ES2088928T3 (es) | 1996-10-01 |
| DE69026881D1 (de) | 1996-06-13 |
| NZ234856A (en) | 1992-08-26 |
| IL95358A0 (en) | 1991-06-30 |
| DE69026881T2 (de) | 1996-09-12 |
| NO903564L (no) | 1991-02-18 |
| FI904035A0 (fi) | 1990-08-15 |
| KR910004649A (ko) | 1991-03-29 |
| IL95358A (en) | 1995-03-30 |
| IE72516B1 (en) | 1997-04-23 |
| DD299650A5 (de) | 1992-04-30 |
| ZA906308B (en) | 1991-06-26 |
| EP0413270A2 (en) | 1991-02-20 |
| ATE137761T1 (de) | 1996-05-15 |
| AU6087790A (en) | 1991-02-21 |
| CN1050196A (zh) | 1991-03-27 |
| PT94993A (pt) | 1991-04-18 |
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