NO902099L - Analogifremgangsmaate for fremstilling av terapeutisk aktive arylsulfonamider. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive arylsulfonamider.

Info

Publication number
NO902099L
NO902099L NO90902099A NO902099A NO902099L NO 902099 L NO902099 L NO 902099L NO 90902099 A NO90902099 A NO 90902099A NO 902099 A NO902099 A NO 902099A NO 902099 L NO902099 L NO 902099L
Authority
NO
Norway
Prior art keywords
arylsulphonamides
thromboxane
preparation
therapeutic active
addition salts
Prior art date
Application number
NO90902099A
Other languages
English (en)
Other versions
NO902099D0 (no
NO176176B (no
NO176176C (no
Inventor
Armin Heckel
Josef Nickl
Rainer Soyka
Wolfgang Eisert
Thomas Mueller
Johannes Weisenberger
Christopher Meade
Gojko Muacevic
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3915506A external-priority patent/DE3915506A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO902099D0 publication Critical patent/NO902099D0/no
Publication of NO902099L publication Critical patent/NO902099L/no
Publication of NO176176B publication Critical patent/NO176176B/no
Publication of NO176176C publication Critical patent/NO176176C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO902099A 1989-05-12 1990-05-11 Analogifremgangsmåte for fremstilling av terapeutisk aktive arylsulfonamider NO176176C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3915506A DE3915506A1 (de) 1989-05-12 1989-05-12 Neue arylsulfonamide, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3932403A DE3932403A1 (de) 1989-05-12 1989-09-28 Neue arylsulfonamide, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
NO902099D0 NO902099D0 (no) 1990-05-11
NO902099L true NO902099L (no) 1990-11-13
NO176176B NO176176B (no) 1994-11-07
NO176176C NO176176C (no) 1995-02-15

Family

ID=25880794

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902099A NO176176C (no) 1989-05-12 1990-05-11 Analogifremgangsmåte for fremstilling av terapeutisk aktive arylsulfonamider

Country Status (21)

Country Link
US (3) US5294626A (no)
EP (1) EP0397044B1 (no)
JP (1) JP2868283B2 (no)
KR (1) KR0153527B1 (no)
AT (1) ATE132138T1 (no)
AU (1) AU627024B2 (no)
CA (1) CA2016646C (no)
DE (2) DE3932403A1 (no)
DK (1) DK0397044T3 (no)
ES (1) ES2083394T3 (no)
FI (1) FI95372C (no)
GR (1) GR3019044T3 (no)
HU (1) HU214586B (no)
IE (1) IE74207B1 (no)
IL (1) IL94347A0 (no)
MX (1) MX9202816A (no)
NO (1) NO176176C (no)
NZ (1) NZ233638A (no)
PT (1) PT93994B (no)
RU (1) RU2096405C1 (no)
UA (1) UA26136C2 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153214A (en) * 1989-06-28 1992-10-06 Ciba-Geigy Corporation Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
DE4025818A1 (de) * 1990-08-16 1992-02-20 Bayer Ag Phenylsulfonamid substituierte pyridinalken- und -aminooxyalkancarbonsaeure-derivate
US5286736A (en) * 1990-11-22 1994-02-15 Dr. Karl Thomae Gmbh Pyridyl compounds and pharmaceutical compositions containing these compounds
DE4037112A1 (de) * 1990-11-22 1992-05-27 Thomae Gmbh Dr K Neue pyridylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US5374641A (en) * 1991-02-25 1994-12-20 Terumo Kabushiki Kaisha N-(3-pyridylalkyl)sulfonamide compounds which have useful pharmaceutical activity
GB9107043D0 (en) * 1991-04-04 1991-05-22 Pfizer Ltd Therapeutic agents
DE4216364A1 (de) * 1991-12-14 1993-11-25 Thomae Gmbh Dr K Neue Pyridylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
FR2686339B1 (fr) * 1992-01-22 1994-03-11 Adir Cie Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DE4213919A1 (de) * 1992-04-28 1993-11-04 Thomae Gmbh Dr K Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CA2347939C (en) 1998-10-23 2006-10-10 Akira Matsumori Composition for the treatment of rheumatism, hepatitis or pancreatitis
US8633237B2 (en) 2009-04-09 2014-01-21 Merck Sharp & Dohme B.V. Indane derivatives
KR101701943B1 (ko) 2009-11-13 2017-02-02 도레이 카부시키가이샤 당뇨병의 치료 또는 예방약
US9955802B2 (en) 2015-04-08 2018-05-01 Fasteners For Retail, Inc. Divider with selectively securable track assembly

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1134828A (en) * 1978-12-28 1982-11-02 Tadao Tanouchi Pyridine derivatives
EP0098690B1 (en) * 1982-06-14 1987-09-09 Takeda Chemical Industries, Ltd. Vinyl carboxylic acid derivatives, their production and use
US4518602A (en) * 1982-10-07 1985-05-21 Takeda Chemical Industries, Ltd. Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
US4563446A (en) * 1983-07-27 1986-01-07 Takeda Chemical Industries, Ltd. Thromboxane synthetase inhibiting 3-(1-alkenyl) pyridines
DE3689506D1 (de) * 1985-10-09 1994-02-17 Shell Int Research Neue Acrylsäureamide.
DE3623944A1 (de) * 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
WO1989001330A2 (en) * 1987-08-20 1989-02-23 Smith Kline & French Laboratories Limited W-arylsulphonamidoalkanoic acids for treatment of thromboxane mediated diseases

Also Published As

Publication number Publication date
IE901708L (en) 1990-11-12
EP0397044A3 (de) 1991-10-16
US5426119A (en) 1995-06-20
HU214586B (hu) 1998-04-28
JP2868283B2 (ja) 1999-03-10
KR0153527B1 (ko) 1998-11-16
US5294626A (en) 1994-03-15
EP0397044B1 (de) 1995-12-27
CA2016646A1 (en) 1990-11-12
FI95372B (fi) 1995-10-13
NO902099D0 (no) 1990-05-11
JPH035457A (ja) 1991-01-11
CA2016646C (en) 1999-09-07
NZ233638A (en) 1992-03-26
NO176176B (no) 1994-11-07
AU5492490A (en) 1990-11-15
GR3019044T3 (en) 1996-05-31
PT93994A (pt) 1991-01-08
IE901708A1 (en) 1991-06-19
FI902358A0 (fi) 1990-05-11
FI95372C (fi) 1996-01-25
RU2096405C1 (ru) 1997-11-20
EP0397044A2 (de) 1990-11-14
IE74207B1 (en) 1997-07-16
MX9202816A (es) 1992-06-30
DE3932403A1 (de) 1991-04-11
HU903013D0 (en) 1990-09-28
ATE132138T1 (de) 1996-01-15
US5681961A (en) 1997-10-28
DE59009994D1 (de) 1996-02-08
UA26136C2 (uk) 1999-06-07
ES2083394T3 (es) 1996-04-16
HUT54649A (en) 1991-03-28
PT93994B (pt) 1997-04-30
KR900018031A (ko) 1990-12-20
AU627024B2 (en) 1992-08-13
NO176176C (no) 1995-02-15
DK0397044T3 (da) 1996-05-13
IL94347A0 (en) 1991-03-10

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Free format text: LAPSED IN NOVEMBER 2000