NO893101L - Fremgangsmaate for fremstilling av laktamderivater. - Google Patents

Fremgangsmaate for fremstilling av laktamderivater.

Info

Publication number
NO893101L
NO893101L NO89893101A NO893101A NO893101L NO 893101 L NO893101 L NO 893101L NO 89893101 A NO89893101 A NO 89893101A NO 893101 A NO893101 A NO 893101A NO 893101 L NO893101 L NO 893101L
Authority
NO
Norway
Prior art keywords
group
4alkyl
hydrogen atom
6alkyl
phenyl
Prior art date
Application number
NO89893101A
Other languages
English (en)
Other versions
NO893101D0 (no
NO169714B (no
NO169714C (no
Inventor
Ian Harold Coates
Alexander William Oxford
Peter Charles North
Barry John Price
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888818393A external-priority patent/GB8818393D0/en
Priority claimed from GB898904195A external-priority patent/GB8904195D0/en
Priority claimed from GB898904550A external-priority patent/GB8904550D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO893101D0 publication Critical patent/NO893101D0/no
Priority claimed from HU90608A external-priority patent/HU207078B/hu
Publication of NO893101L publication Critical patent/NO893101L/no
Publication of NO169714B publication Critical patent/NO169714B/no
Publication of NO169714C publication Critical patent/NO169714C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
NO893101A 1988-08-02 1989-08-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive laktamderivater NO169714C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB888818393A GB8818393D0 (en) 1988-08-02 1988-08-02 Chemical compounds
GB898904195A GB8904195D0 (en) 1989-02-23 1989-02-23 Chemical compounds
GB898904550A GB8904550D0 (en) 1989-02-28 1989-02-28 Chemical compounds
HU90608A HU207078B (en) 1988-08-02 1990-01-31 Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds

Publications (4)

Publication Number Publication Date
NO893101D0 NO893101D0 (no) 1989-08-01
NO893101L true NO893101L (no) 1990-02-05
NO169714B NO169714B (no) 1992-04-21
NO169714C NO169714C (no) 1992-07-29

Family

ID=27450153

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893101A NO169714C (no) 1988-08-02 1989-08-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive laktamderivater

Country Status (14)

Country Link
EP (1) EP0353983B1 (no)
JP (1) JPH02160786A (no)
AT (1) ATE138659T1 (no)
AU (1) AU631131B2 (no)
CA (1) CA1336906C (no)
DE (1) DE68926553T2 (no)
DK (1) DK169922B1 (no)
ES (1) ES2088389T3 (no)
FI (1) FI92067C (no)
GR (1) GR3020349T3 (no)
IL (1) IL91167A (no)
NO (1) NO169714C (no)
NZ (1) NZ230154A (no)
PT (1) PT91336B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87658A (en) * 1987-09-03 1994-06-24 Glaxo Group Ltd Tetrahydro-H-) -12-imidazolylmethyl (pyrido-) and azapino- (] B) -4,3 ([indole-1-ointments, their preparation and pharmaceutical preparations containing them
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
GB9011469D0 (en) * 1990-05-23 1990-07-11 Glaxo Group Ltd Chemical process
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
EP0581388A1 (en) * 1992-07-30 1994-02-02 Glaxo Group Limited Pyridoindolone Methansulphonate as 5HT and 5HT3 receptor antagonists
GB9216154D0 (en) * 1992-07-30 1992-09-09 Glaxo Group Ltd Chemical compounds
CA2212092A1 (en) * 1995-12-01 1997-06-12 Makoto Shibata Pyrroloazepine derivatives
JP2004502642A (ja) * 2000-02-11 2004-01-29 ブリストル−マイヤーズ　スクイブ　カンパニー カンナビノイドレセプターモジュレーター、それらの製造方法、および呼吸系および非呼吸系疾患の処置のためのカンナビノイドレセプターモジュレーターの使用
US6849640B2 (en) 2001-08-08 2005-02-01 Pharmacia & Upjohn Company Therapeutic 1H-pyrido [4,3-b] indoles
US6770655B2 (en) 2002-01-18 2004-08-03 Aryx Therapeutics 5-HT3 receptor antagonists and methods of use
GB0305553D0 (en) * 2003-03-11 2003-04-16 Glaxo Group Ltd Compounds
DE602006013688D1 (de) 2005-11-16 2010-05-27 Hoffmann La Roche Neues verfahren zur herstellung von thoc
RU2007139634A (ru) 2007-10-25 2009-04-27 Сергей Олегович Бачурин (RU) Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения
CN102480956B (zh) 2009-04-29 2015-04-08 梅迪维新技术公司 吡啶并[4,3-b]吲哚类和使用方法
WO2010127177A1 (en) 2009-04-29 2010-11-04 Medivation Technologies, Inc. Pyrido [4,3-b] indoles and methods of use
EP2253316B1 (en) 2009-05-20 2013-08-14 INSERM (Institut National de la Santé et de la Recherche Médicale) Serotonin 5-HT3 receptor antagonists for use in the treatment or prevention of an inner ear pathology with vestibular deficits
SI2432467T1 (en) 2009-05-20 2018-06-29 Inserm (Institut National De La Sante Et De La Recherche Medicale) ANTAGONIST RECEPTOR SEROTONINA 5-HT3 FOR THE USE IN THE TREATMENT OF LEASE VESTIBULAR DISEASES
US8815843B2 (en) 2011-02-18 2014-08-26 Medivation Technologies, Inc. Compounds and methods of treating diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
IL87658A (en) * 1987-09-03 1994-06-24 Glaxo Group Ltd Tetrahydro-H-) -12-imidazolylmethyl (pyrido-) and azapino- (] B) -4,3 ([indole-1-ointments, their preparation and pharmaceutical preparations containing them
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
IL91167A (en) 1993-06-10
IL91167A0 (en) 1990-03-19
FI92067B (fi) 1994-06-15
EP0353983B1 (en) 1996-05-29
AU631131B2 (en) 1992-11-19
JPH02160786A (ja) 1990-06-20
DK169922B1 (da) 1995-04-03
EP0353983A2 (en) 1990-02-07
FI92067C (fi) 1994-09-26
ATE138659T1 (de) 1996-06-15
EP0353983A3 (en) 1990-07-25
CA1336906C (en) 1995-09-05
FI893634A (fi) 1990-02-03
PT91336B (pt) 1995-05-04
NZ230154A (en) 1991-10-25
GR3020349T3 (en) 1996-09-30
NO893101D0 (no) 1989-08-01
DK377889D0 (da) 1989-08-01
DE68926553D1 (de) 1996-07-04
DK377889A (da) 1990-02-03
ES2088389T3 (es) 1996-08-16
PT91336A (pt) 1990-03-08
DE68926553T2 (de) 1996-10-17
AU3918689A (en) 1990-02-08
NO169714B (no) 1992-04-21
NO169714C (no) 1992-07-29
FI893634A0 (fi) 1989-08-01

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