NO892986D0 - SELECTIVE O-ACYLATED GYCLOSAM COLLECTION. - Google Patents

SELECTIVE O-ACYLATED GYCLOSAM COLLECTION.

Info

Publication number
NO892986D0
NO892986D0 NO892986A NO892986A NO892986D0 NO 892986 D0 NO892986 D0 NO 892986D0 NO 892986 A NO892986 A NO 892986A NO 892986 A NO892986 A NO 892986A NO 892986 D0 NO892986 D0 NO 892986D0
Authority
NO
Norway
Prior art keywords
acylated
gyclosam
selective
collection
groups
Prior art date
Application number
NO892986A
Other languages
Norwegian (no)
Other versions
NO892986L (en
Inventor
Maurice Petitou
Jean-Claude Lormeau
Jean Choay
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO892986D0 publication Critical patent/NO892986D0/en
Publication of NO892986L publication Critical patent/NO892986L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The glycosaminoglycans of the invention are selectively O-acylated in a controllable manner on their free -OH groups, the carboxylic or amino functional groups being unaltered. These compounds have a pharmacological activity of very long duration.
NO89892986A 1988-07-21 1989-07-20 SELECTIVE O-ACYLATED GYCLOSAM COLLECTION. NO892986L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8809885A FR2634485B1 (en) 1988-07-21 1988-07-21 SELECTIVELY O-ACYLATED GLYCOSAMINOGLYCANS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
NO892986D0 true NO892986D0 (en) 1989-07-20
NO892986L NO892986L (en) 1990-01-22

Family

ID=9368648

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89892986A NO892986L (en) 1988-07-21 1989-07-20 SELECTIVE O-ACYLATED GYCLOSAM COLLECTION.

Country Status (23)

Country Link
EP (1) EP0356275B1 (en)
JP (1) JPH0273801A (en)
KR (1) KR910002889A (en)
AT (1) ATE108804T1 (en)
AU (1) AU620632B2 (en)
DD (1) DD285606A5 (en)
DE (1) DE68916878T2 (en)
DK (1) DK362789A (en)
ES (1) ES2056239T3 (en)
FI (1) FI893518A (en)
FR (1) FR2634485B1 (en)
HU (1) HU206222B (en)
IE (1) IE892367L (en)
IL (1) IL91058A0 (en)
MA (1) MA21602A1 (en)
NO (1) NO892986L (en)
NZ (1) NZ230041A (en)
OA (1) OA09125A (en)
PT (1) PT91249B (en)
RU (1) RU1831487C (en)
TN (1) TNSN89082A1 (en)
YU (1) YU172789A (en)
ZA (1) ZA895581B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2669932B1 (en) * 1990-12-03 1994-07-01 Sanofi Sa NOVEL HEPAROSANE-N, O-SULFATE, ITS PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING IT.
US5990095A (en) 1991-07-03 1999-11-23 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
US5834444A (en) * 1991-07-03 1998-11-10 Hyal Pharmaceutical Corporation Hyaluronic acid and salts thereof inhibit arterial restenosis
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them
US5498775A (en) * 1994-11-07 1996-03-12 American Home Products Corporation Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
US5565432A (en) * 1994-11-07 1996-10-15 American Home Products Corporation Smooth muscle cell proliferation inhibitors
IT1286510B1 (en) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po BUTYRIC ESTERS WITH ANTI-PROLIFERATIVE ACTIVITY AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
CA2317305A1 (en) 2000-08-29 2002-02-28 Tassos P. Anastassiades Method of enhancing chondrocyte cell growth and glycosaminoglycan production
KR20030057040A (en) * 2001-12-28 2003-07-04 주식회사 효성 D-Glucosamine derivatives and Method for Preparing Thereof
KR100790007B1 (en) * 2006-12-28 2008-01-02 경상대학교산학협력단 A method for purification glycosaminoglycans from ascidian tunic
CA3020369C (en) * 2010-09-14 2019-11-26 University Of Miyazaki High purity heparin and production method therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3066M (en) * 1963-08-07 1965-01-18 Roussel Uclaf New drug, in particular for the treatment of postprandial or chronic hyperlipemia.
JPS469327B1 (en) * 1966-03-31 1971-03-09
JPS52111983A (en) * 1976-03-18 1977-09-20 Teijin Ltd Preparation of heparin derivatives
US4331697A (en) * 1980-09-02 1982-05-25 Teijin Limited Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative
FR2584728B1 (en) * 1985-07-12 1987-11-20 Choay Sa PROCESS FOR THE SULFATION OF GLYCOSAMINOGLYCANS AND THEIR FRAGMENTS
JP5410580B1 (en) * 2012-08-09 2014-02-05 日本特殊陶業株式会社 Wiring board

Also Published As

Publication number Publication date
DE68916878D1 (en) 1994-08-25
IE892367L (en) 1990-01-21
MA21602A1 (en) 1990-04-01
DD285606A5 (en) 1990-12-19
AU3885689A (en) 1990-01-25
TNSN89082A1 (en) 1991-02-04
PT91249A (en) 1990-02-08
FR2634485A1 (en) 1990-01-26
NZ230041A (en) 1991-09-25
RU1831487C (en) 1993-07-30
DK362789A (en) 1990-01-22
HUT50489A (en) 1990-02-28
ATE108804T1 (en) 1994-08-15
YU172789A (en) 1991-08-31
DE68916878T2 (en) 1995-03-16
JPH0273801A (en) 1990-03-13
FR2634485B1 (en) 1992-02-28
NO892986L (en) 1990-01-22
AU620632B2 (en) 1992-02-20
PT91249B (en) 1995-05-04
ES2056239T3 (en) 1994-10-01
DK362789D0 (en) 1989-07-21
HU206222B (en) 1992-09-28
OA09125A (en) 1991-10-31
FI893518A (en) 1990-01-22
IL91058A0 (en) 1990-02-09
KR910002889A (en) 1991-02-26
FI893518A0 (en) 1989-07-21
EP0356275B1 (en) 1994-07-20
EP0356275A1 (en) 1990-02-28
ZA895581B (en) 1990-04-25

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